100 Years of Human Chorionic Gonadotropin

100 years of Human Chorionic Gonadotropin: Reviews and New Perspectives is a collection of articles written by some of the world’s leading experts on the pregnancy hormone and cancer marker hCG. In 2019 it is difficult to ignore the effect that our understanding of hCG has had on the lives of millions of people worldwide. The hCG immunoassay, in one form or another, is now one of the most common medical tests conducted and is often the first indication that a mother-to-be is pregnant. Not only a marker of pregnancy, hCG is utilized in the diagnosis and monitoring in oncology and presents a potential target for novel cancer therapeutics. 100 years ago, in 1919, Hirose was demonstrating gonadotropic functions which resulted from a chorionic factor. Over the last century this factor has become defined as hCG and more recently explored as not one molecule but a group of molecules with variable structure and variable functions in both pregnancy and cancer. hCG is a multi-faceted molecule that has clinical and therapeutic implications but can be a challenging topic for researchers and physicians alike. This text covers the different structures and functions of hCG exploring the genes and evolution of the molecule, the different protein and glycosylation structures which can exist and their effect on structure, detection and quantification. 100 Years of hCG is not an attempt to recount the history of every publication on hCG, but rather a collection of reviews and new perspectives by "hCG-ologists", the term used by Hussa to describe biochemists working on HCG in the first book written on the topic over 30 years ago. Some of the authors have been around a while, some not so long, but others are just beginning their journey with a most beguiling molecule. Provides updated information on a complex and changing subject in five sections Reviews historical perspectives and developments over the last 100 years Includes novel insights into the structure, function and detection of hCG in pregnancy and cancer Includes chapters on the use of mass spectrometry to detect and quantify hCG as well as traditional immunoassays and over the counter pregnancy tests Describes the role of hCG in pregnancy, endometrial receptivity and embryo implantation and the use in fertility treatment Addresses the specific hyperglycosylated hCG test that can distinguish a normal term from a failing pregnancy and also screen for preeclampsia and gestational hypertension in pregnancy as well as its use as a marker and treatment target in cancer. Includes chapters on the development and use of hCG vaccines Includes a section on hCG and in subunits in cancer

Produk Detail:

  • Author : Laurence A. Cole
  • Publisher : Elsevier
  • Pages : 358 pages
  • ISBN : 0128216093
  • Rating : 4/5 from 21 reviews
CLICK HERE TO GET THIS BOOK100 Years of Human Chorionic Gonadotropin

100 Years of Human Chorionic Gonadotropin

100 Years of Human Chorionic Gonadotropin
  • Author : Laurence A. Cole,Stephen A. Butler
  • Publisher : Elsevier
  • Release : 07 February 2020
GET THIS BOOK100 Years of Human Chorionic Gonadotropin

100 years of Human Chorionic Gonadotropin: Reviews and New Perspectives is a collection of articles written by some of the world’s leading experts on the pregnancy hormone and cancer marker hCG. In 2019 it is difficult to ignore the effect that our understanding of hCG has had on the lives of millions of people worldwide. The hCG immunoassay, in one form or another, is now one of the most common medical tests conducted and is often the first indication that a

Animal Models in Eye Research

Animal Models in Eye Research
  • Author : Anonim
  • Publisher : Academic Press
  • Release : 28 April 2011
GET THIS BOOKAnimal Models in Eye Research

The eye is a complex sensory organ, which enables visual perception of the world. Thus the eye has several tissues that do different tasks. One of the most basic aspects of eye function is the sensitivity of cells to light and its transduction though the optic nerve to the brain. Different organisms use different ways to achieve these tasks. In this sense, eye function becomes a very important evolutionary aspect as well. This book presents the different animal models that

Human Chorionic Gonadotropin (hCG)

Human Chorionic Gonadotropin (hCG)
  • Author : Laurence A. Cole,Stephen A. Butler
  • Publisher : Elsevier
  • Release : 20 January 2021
GET THIS BOOKHuman Chorionic Gonadotropin (hCG)

This resource describes the detailed biology, clinical chemistry, and clinical perspectives of HCG and associated molecules and examines HCG, hyperglycosylated HCG, and HCG free-subunit, three separate and independent molecules with totally sovereign physiological functions.

In-Vitro Fertilization

In-Vitro Fertilization
  • Author : Gabor Kovacs,Peter Brinsden,Alan DeCherney
  • Publisher : Unknown Publisher
  • Release : 14 June 2018
GET THIS BOOKIn-Vitro Fertilization

A stimulating record chartering the history and pioneers of in-vitro fertilization, forty years after the birth of the first baby.

Perinatal Programming

Perinatal Programming
  • Author : Andreas Plagemann
  • Publisher : Walter de Gruyter
  • Release : 01 January 2012
GET THIS BOOKPerinatal Programming

Perinatal Programming addresses the environment-dependent setting of fundamental life functions and dispositions for diseases in developmental periods during pregnancy and in early infancy. It provides a new view of the origins of health and diseases. To realize these associations may enable us to prevent diseases for the long term. This book reviews actual state-of-the-art knowledge in the perinatal programming field. The authors are internationally known scientists of this research area.

Tietz Textbook of Clinical Chemistry and Molecular Diagnostics - E-Book

Tietz Textbook of Clinical Chemistry and Molecular Diagnostics - E-Book
  • Author : Carl A. Burtis,Edward R. Ashwood,David E. Bruns
  • Publisher : Elsevier Health Sciences
  • Release : 14 October 2012
GET THIS BOOKTietz Textbook of Clinical Chemistry and Molecular Diagnostics - E-Book

As the definitive reference for clinical chemistry, Tietz Textbook of Clinical Chemistry and Molecular Diagnostics, 5th Edition offers the most current and authoritative guidance on selecting, performing, and evaluating results of new and established laboratory tests. Up-to-date encyclopedic coverage details everything you need to know, including: analytical criteria for the medical usefulness of laboratory procedures; new approaches for establishing reference ranges; variables that affect tests and results; the impact of modern analytical tools on lab management and costs; and applications

Diagnostic Gynecologic and Obstetric Pathology E-Book

Diagnostic Gynecologic and Obstetric Pathology E-Book
  • Author : Christopher P. Crum,Kenneth R. Lee,Marisa R. Nucci
  • Publisher : Elsevier Health Sciences
  • Release : 16 February 2011
GET THIS BOOKDiagnostic Gynecologic and Obstetric Pathology E-Book

Drs. Christopher P. Crum, Marisa R. Nucci, and Kenneth R. Lee help you diagnose neoplastic and non-neoplastic lesions of the female reproductive tract with their comprehensive update of Diagnostic Gynecologic and Obstetric Pathology. This 2nd Edition provides all of the latest guidance needed to accurately evaluate pathologic features and morphologic patterns. With 650+ new color images, an appendix with algorithms for the use of biomarkers, key points, diagnostic pearls, and more... this title is a must-have for today’s pathologist. Find

Thyroid Disorders and Diseases, An Issue of Medical Clinics - E-Book

Thyroid Disorders and Diseases, An Issue of Medical Clinics - E-Book
  • Author : Kenneth Burman
  • Publisher : Elsevier Health Sciences
  • Release : 11 April 2012
GET THIS BOOKThyroid Disorders and Diseases, An Issue of Medical Clinics - E-Book

This issue of Medical Clinics of North America provides the latest essential updates on thyroid disorders and diseases. Topics covered include the following: thyroid synthesis and physiology; hyperthyroidism; hypothyroidism; thyroid nodules; goiter; differentiated thyroid cancer; subacute, silent, and postpartum thyroiditis; thyroid and pregnancy; thyroid and the elderly; medications and thyroid hormones; thyroid and the heart; thyroid and lipids; and Graves’ ophthalmology.

Clinical Management of Thyroid Disease E-Book

Clinical Management of Thyroid Disease E-Book
  • Author : Fredric E. Wondisford,Sally Radovick
  • Publisher : Elsevier Health Sciences
  • Release : 26 June 2009
GET THIS BOOKClinical Management of Thyroid Disease E-Book

Clinical Management of Thyroid Disease is an exciting new book edited by Fredric Wondisford, MD—developer of the revolutionary new drug, Thyrotropin—and Sally Radovick, MD, with contributions from experts in the field. It fulfills the niche of a succinct, clinical resource to help you translate research into practice. This full-color volume offers valuable information on thyroid cancer and non-cancerous lesions, the effect of drugs on thyroid function, genetic disorders, and more in an accessible, easy-to-read consistent format. Presents the

Knobil and Neill's Physiology of Reproduction

Knobil and Neill's Physiology of Reproduction
  • Author : Tony M. Plant,Anthony J. Zeleznik
  • Publisher : Academic Press
  • Release : 15 November 2014
GET THIS BOOKKnobil and Neill's Physiology of Reproduction

The Fourth Edition of Knobil & Neill continues to serve as a reference aid for research, to provide the historical context to current research, and most importantly as an aid for graduate teaching on a broad range of topics in human and comparative reproduction. In the decade since the publication of the last edition, the study of reproductive physiology has undergone monumental changes. Chief among these advances are in the areas of stem cell development, signaling pathways, the role of inflammation