A Paradigm Shift to Prevent and Treat Alzheimer s Disease

A Paradigm Shift to Prevent and Treat Alzheimer’s Disease: From Monotargeting Pharmaceuticals to Pleiotropic Plant Polyphenols is the first book to systematically exhibit the powerful pleiotropic pharmacological effects on Alzheimer’s disease of plant-based compounds from ancient foods that humans have been consuming safely with substantial health benefits for thousands of years. These plant-based compounds include curcuminoids from turmeric, resveratrol from red wine and grape seed extract from other grape products, epigallocatechin-gallate (EGCG) from green tea, and oleocanthal and oleuropein from olive oil, in addition to a special extract, EGb 761, from the leaves of Ginkgo biloba, the oldest living species of tree on earth. This book also presents a new analytical framework that convincingly favors a multi-targeting ("pleiotropic") approach to the prevention and treatment of complex chronic diseases, in contrast to the mono-targeting of the pharmaceutical model. A Paradigm Shift to Prevent and Treat Alzheimer’s Disease is a unique and exciting resource for pharmaceutical scientists, pharmacologists, neurologists, general practitioners, research scientists in various medical and life sciences, healthcare professionals in clinical and executive positions, conventional medical schools, schools of naturopathic medicine, healthcare and medical journalists, executives in both national public healthcare systems and private insurers, and informed general readers. Presents carefully compiled evidence supporting the need to shift from pharmaceutical-based mono-targeting to plant polyphenol-based pleiotropic targeting for the prevention and treatment of Alzheimer’s disease Includes valuable tables that aggregate pleiotropic pharmacological effects of the plant polyphenols on Alzheimer’s disease-related pathogenic hallmarks Highlights regulatory aspects and discusses the challenges and potential solutions with respect to bioavailability of certain plant polyphenols

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  • Author : Howard Friel
  • Publisher : Academic Press
  • Pages : 290 pages
  • ISBN : 012812279X
  • Rating : 4/5 from 21 reviews
CLICK HERE TO GET THIS BOOKA Paradigm Shift to Prevent and Treat Alzheimer s Disease

A Paradigm Shift to Prevent and Treat Alzheimer's Disease

A Paradigm Shift to Prevent and Treat Alzheimer's Disease
  • Author : Howard Friel,Sally A. Frautschy
  • Publisher : Academic Press
  • Release : 18 July 2017
GET THIS BOOKA Paradigm Shift to Prevent and Treat Alzheimer's Disease

A Paradigm Shift to Prevent and Treat Alzheimer’s Disease: From Monotargeting Pharmaceuticals to Pleiotropic Plant Polyphenols is the first book to systematically exhibit the powerful pleiotropic pharmacological effects on Alzheimer’s disease of plant-based compounds from ancient foods that humans have been consuming safely with substantial health benefits for thousands of years. These plant-based compounds include curcuminoids from turmeric, resveratrol from red wine and grape seed extract from other grape products, epigallocatechin-gallate (EGCG) from green tea, and oleocanthal and

The End of Alzheimer's

The End of Alzheimer's
  • Author : Dale Bredesen
  • Publisher : Penguin
  • Release : 22 August 2017
GET THIS BOOKThe End of Alzheimer's

The instant New York Times and Wall Street Journal bestseller A groundbreaking plan to prevent and reverse Alzheimer’s Disease that fundamentally changes how we understand cognitive decline. Everyone knows someone who has survived cancer, but until now no one knows anyone who has survived Alzheimer's Disease. In this paradigm shifting book, Dale Bredesen, MD, offers real hope to anyone looking to prevent and even reverse Alzheimer's Disease and cognitive decline. Revealing that AD is not one condition, as it

The Alzheimer Conundrum

The Alzheimer Conundrum
  • Author : Margaret Lock
  • Publisher : Princeton University Press
  • Release : 20 October 2015
GET THIS BOOKThe Alzheimer Conundrum

Due to rapidly aging populations, the number of people worldwide experiencing dementia is increasing, and the projections are grim. Despite billions of dollars invested in medical research, no effective treatment has been discovered for Alzheimer's disease, the most common form of dementia. The Alzheimer Conundrum exposes the predicaments embedded in current efforts to slow down or halt Alzheimer’s disease through early detection of pre-symptomatic biological changes in healthy individuals. Based on a meticulous account of the history of Alzheimer’

The End of Alzheimer's Program

The End of Alzheimer's Program
  • Author : Dale Bredesen
  • Publisher : Penguin
  • Release : 18 August 2020
GET THIS BOOKThe End of Alzheimer's Program

The instant New York Times bestseller The New York Times Best Selling author of The End of Alzheimer's lays out a specific plan to help everyone prevent and reverse cognitive decline or simply maximize brainpower. In The End of Alzheimer's Dale Bredesen laid out the science behind his revolutionary new program that is the first to both prevent and reverse symptoms of Alzheimer's disease. Now he lays out the detailed program he uses with his own patients. Accessible and detailed,

Animal Experimentation

Animal Experimentation
  • Author : Kathrin Herrmann,Kimberley Jayne
  • Publisher : Human-Animal Studies
  • Release : 17 April 2021
GET THIS BOOKAnimal Experimentation

Animal Experimentation: Working Towards a Paradigm Change critically appraises current animal use in science and discusses ways in which we can contribute to a paradigm change towards human-biology based approaches.

The Biology of Alzheimer Disease

The Biology of Alzheimer Disease
  • Author : Dennis J. Selkoe,David Michael Holtzman,Eckhard Mandelkow
  • Publisher : Unknown Publisher
  • Release : 17 April 2021
GET THIS BOOKThe Biology of Alzheimer Disease

Alzheimer Disease represents an important area of research in neurobiology, cell biology, developmental biology and pathology. Understanding the nature of the changes that occur in neurons as the disease progresses — accumulation of amyloid beta and neurofibrillary tangles — is obviously important as we try to develop therapeutic approaches. Moreover, the normal physiological roles of proteins such as APP and tau, whose processing appears to be altered in Alzheimer Disease, is also an intense area of research.

The Best American Essays 2002

The Best American Essays 2002
  • Author : Stephen Jay Gould,Robert Atwan
  • Publisher : Houghton Mifflin Harcourt
  • Release : 17 April 2021
GET THIS BOOKThe Best American Essays 2002

Edited by the award-winning late author of The Mismeasure of Man a new collection of the finest nonfiction essays published over the past year incorporates the work of distinguished masters of the essay genre on topics ranging from pathology to the boxing arena to growing up.

Brain Fables

Brain Fables
  • Author : Alberto Espay,Benjamin Stecher
  • Publisher : Cambridge University Press
  • Release : 30 June 2020
GET THIS BOOKBrain Fables

"In Sapiens, Yuval Noah Harari argues that humankind's greatest invention is our ability to create and believe fictions. While all other animals communicate realities with which they interact, humans create a separate layer of subjective, interpretative realities. The fiction most universally embraced today is money. "Dollar bills have absolutely no value except in our collective imagination, but everybody believes in the dollar bill," says Harari. Harari goes on to state that humans have been living in a dual reality. "On

Chemistry and Molecular Aspects of Drug Design and Action

Chemistry and Molecular Aspects of Drug Design and Action
  • Author : E. A. Rekka,P. N. Kourounakis
  • Publisher : CRC Press
  • Release : 28 April 2008
GET THIS BOOKChemistry and Molecular Aspects of Drug Design and Action

An ever-increasing demand for better drugs, elevated safety standards, and economic considerations have all led to a dramatic paradigm shift in the way that drugs are being discovered and developed. Known as rational drug design, this contemporary process is defined by three main steps: the discovery of lead compounds, surgical manipulation to deve

The Oxford Handbook of Medical Ethnomusicology

The Oxford Handbook of Medical Ethnomusicology
  • Author : Benjamin Koen,Jacqueline Lloyd,Gregory Barz,Karen Brummel-Smith
  • Publisher : OUP USA
  • Release : 27 April 2011
GET THIS BOOKThe Oxford Handbook of Medical Ethnomusicology

The Oxford Handbook of Medical Ethnomusicology defines a new field of holistic research and applied practice that approaches music, health, and healing across traditional cultures worldwide and the disciplinary boundaries of ethnomusicology, music therapy, the health sciences, and alternative medicine.