Adenosine Receptors in Neurodegenerative Diseases

Adenosine Receptors in Neurodegenerative Diseases covers the role of adenosine receptors in brain function, also focusing on related methodologies and perspectives in therapeutics. The book provides an up-to-date overview by the best specialists in the field, helping readers consider the importance of adenosine and expand the global impact and visibility of adenosine research in the CNS field. Chapters include adenosine biology and signaling, gene regulation, control of motor function, and novel adenosine-based therapies in the CNS. It is an ideal resource for researchers, advanced graduate students, clinicians, and industry scientists working in the fields of clinical neuroscience and molecular and cellular neuroscience. Comprehensive reference that details adenosine receptors in neurodegenerative disorders, with details on brain function and possible therapeutics Gives insights on how these receptors modulate the neurodegenerative outcomes in different disorders Edited by two of the leading researchers in the field regarding adenosine role in the brain in aging and neurodegenerative conditions

Produk Detail:

  • Author : David Blum
  • Publisher : Academic Press
  • Pages : 280 pages
  • ISBN : 0128037458
  • Rating : 4/5 from 21 reviews
CLICK HERE TO GET THIS BOOKAdenosine Receptors in Neurodegenerative Diseases

Adenosine Receptors in Neurodegenerative Diseases

Adenosine Receptors in Neurodegenerative Diseases
  • Author : David Blum,Luisa V. Lopes
  • Publisher : Academic Press
  • Release : 10 March 2017
GET THIS BOOKAdenosine Receptors in Neurodegenerative Diseases

Adenosine Receptors in Neurodegenerative Diseases covers the role of adenosine receptors in brain function, also focusing on related methodologies and perspectives in therapeutics. The book provides an up-to-date overview by the best specialists in the field, helping readers consider the importance of adenosine and expand the global impact and visibility of adenosine research in the CNS field. Chapters include adenosine biology and signaling, gene regulation, control of motor function, and novel adenosine-based therapies in the CNS. It is an ideal

Adenosine Receptors in Health and Disease

Adenosine Receptors in Health and Disease
  • Author : Constance N. Wilson,S. Jamal Mustafa
  • Publisher : Springer Science & Business Media
  • Release : 28 July 2009
GET THIS BOOKAdenosine Receptors in Health and Disease

Since their discovery approximately 25 years ago, adenosine receptors have now emerged as important novel molecular targets in disease and drug discovery. These proteins play important roles in the entire spectrum of disease from inflammation to immune suppression. Because of their expression on a number of different cell types and in a number of different organ systems they play important roles in specific diseases, including asthma, rheumatoid arthritis, Parkinson’s disease, multiple sclerosis, Alzheimer’s disease, heart disease, stroke, cancer, sepsis,

Adenosine Receptors and Parkinson's Disease

Adenosine Receptors and Parkinson's Disease
  • Author : Hiroshi Kase,Peter J. Richardson,Peter Jenner
  • Publisher : Elsevier
  • Release : 27 October 1999
GET THIS BOOKAdenosine Receptors and Parkinson's Disease

This book is the first definitive overview on adenosine receptor antagonists and their application to the treatment of Parkinson's Disease. The effect of these novel non-dopamine drugs on vitro and in vivo systems clearly shows their potential for the treatment of this debilitating disease. This book covers how the Parkinson's disease antagonist drug, A2A, has been researched, developed, and tested. It is an essential book for researchers interested in the basal ganglia, purine biology, and Parkinson's Disease. Discusses the

The Adenosine Receptors

The Adenosine Receptors
  • Author : Pier Andrea Borea,Katia Varani,Stefania Gessi,Stefania Merighi,Fabrizio Vincenzi
  • Publisher : Humana Press
  • Release : 28 July 2018
GET THIS BOOKThe Adenosine Receptors

This book traces the history of adenosine receptor research from molecular biology to medicinal chemistry to behavior, including their implications in disease and potential strategies as therapeutic targets. It provides the reader with a comprehensive overview of the adenosine receptors that includes information on all subtypes - A1, A2A, A2B and A3. Aspects addressed include the most up to date information on their functional distribution in the nervous and peripheral systems, behavioral roles in inflammation, cancer, pain and

Adenosine Receptors

Adenosine Receptors
  • Author : Gyorgy Hasko,Bruce N. Cronstein,Csaba Szabo
  • Publisher : CRC Press
  • Release : 20 July 2006
GET THIS BOOKAdenosine Receptors

After a century of research, several lines of evidence now indicate that the ability of adenosine to directly control inflammatory cells has a major impact on the functions of the inflammatory and immune systems. Consequently, many promising therapeutic approaches are beginning to emerge that focus on the modulation of adenosine, including the development of compounds that interfere with the breakdown of adenosine, as well as specific agonists and antagonists of various adenosine subtypes. Some of these compounds have already entered

The Adenosinergic System

The Adenosinergic System
  • Author : Micaela Morelli,Nicola Simola,Jadwiga Wardas
  • Publisher : Springer
  • Release : 01 October 2015
GET THIS BOOKThe Adenosinergic System

Adenosine A2A receptor antagonists have shown great promise in the treatment of Parkinson's Disease and alleviation of symptoms. This book addresses various aspects of this class of drugs from their chemical development to their clinical use. Among the many insightful chapters contained in this book, there are three unique reviews that have not previously been published in any format: (1) a history of istradefylline, the first A2A antagonist approved for treatment of Parkinson's Disease, (2) an overview of neuroimaging studies

Adenosine

Adenosine
  • Author : Susan Masino,Detlev Boison
  • Publisher : Springer Science & Business Media
  • Release : 30 August 2012
GET THIS BOOKAdenosine

Homeostasis of key metabolites and metabolic health affects all bodily systems. Not surprisingly, altered metabolic function is associated with a wide spectrum of dysfunctions in the central nervous system – including developmental disorders, acute nervous system injury, and neurodegenerative disorders. Accordingly, metabolism-based therapies offer significant promise as new category of treatment options designed to limit, delay or reverse the disease process by reconstructing homeostatic functions. Increasingly it is appreciated that restoring metabolic health could promote normal nervous system activity, and improve

Adenosine Receptors in Neurology and Psychiatry

Adenosine Receptors in Neurology and Psychiatry
  • Author : Anonim
  • Publisher : Academic Press
  • Release : 28 August 2014
GET THIS BOOKAdenosine Receptors in Neurology and Psychiatry

This well-established international series examines major areas of basic and clinical research within neuroscience, as well as emerging and promising subfields. This volume concentrates on adenosine receptor science, providing insights useful for actual drug discovery/development in neurology and psychiatry areas. Expertise of contributors Subject including practical drug development from basic science, as translational research taste Structure of contents focusing on two CNS areas for diseases (neurology and psychiatry)

Hypoxia and Human Diseases

Hypoxia and Human Diseases
  • Author : Jing Zheng,Chi Zhou
  • Publisher : BoD – Books on Demand
  • Release : 01 February 2017
GET THIS BOOKHypoxia and Human Diseases

This book contains a total of 21 chapters, each of which was written by experts in the corresponding field. The objective of this book is to provide a comprehensive and updated overview of cellular and molecular mechanisms underlying hypoxia's impacts on human health, as well as current advances and future directions in the detection, recognition, and management of hypoxia-related disorders. This collection of articles provides a clear update in the area of hypoxia research for biomedical researchers, medical students, nurse practitioners,

A Synopsis of Parkinson's Disease

A Synopsis of Parkinson's Disease
  • Author : Md, Frcpc, Frcp (hon), Abdul Qayyum Rana
  • Publisher : BoD – Books on Demand
  • Release : 26 March 2014
GET THIS BOOKA Synopsis of Parkinson's Disease

Parkinsons disease is a disabling neurological condition with both motor and non-motor symptoms for which no cure is available at this stage. This book is unique in covering the most important topics related to Parkinsons disease. Current research and updates about some non-motor symptoms, as well as surgical treatment of Parkinsons disease, in addition to the long term complications of pharmacological treatments have been presented. This book can be used by physicians, researchers and neuroscientists who want to learn new

Adenosine Receptors in Neurology and Psychiatry

Adenosine Receptors in Neurology and Psychiatry
  • Author : Anonim
  • Publisher : Academic Press
  • Release : 28 August 2014
GET THIS BOOKAdenosine Receptors in Neurology and Psychiatry

This well-established international series examines major areas of basic and clinical research within neuroscience, as well as emerging and promising subfields. This volume concentrates on adenosine receptor science, providing insights useful for actual drug discovery/development in neurology and psychiatry areas. Expertise of contributors Subject including practical drug development from basic science, as translational research taste Structure of contents focusing on two CNS areas for diseases (neurology and psychiatry)

Interaction Between Neurons and Glia in Aging and Disease

Interaction Between Neurons and Glia in Aging and Disease
  • Author : Joao Malva
  • Publisher : Springer Science & Business Media
  • Release : 09 August 2007
GET THIS BOOKInteraction Between Neurons and Glia in Aging and Disease

A superb source of reference reviews as well as a concise overview of the functional cross-talk between neurons and glial cells, this book also focuses on microglia and inflammation in the aging brain and in neurological disorders. The scientific spectrum covered by this book is of key interest, and is recognized by the scientific community as a major competitive area with critical implications for human health.

RNA Metabolism in Neurodegenerative Diseases

RNA Metabolism in Neurodegenerative Diseases
  • Author : Rita Sattler,Christopher J. Donnelly
  • Publisher : Springer
  • Release : 18 June 2018
GET THIS BOOKRNA Metabolism in Neurodegenerative Diseases

It has become evident over the last years that abnormalities in RNA processing play a fundamental part in the pathogenesis of neurodegenerative diseases. Cellular viability depends on proper regulation of RNA metabolism and subsequent protein synthesis, which requires the interplay of many processes including transcription, pre--‐mRNA splicing, mRNA editing as well as mRNA stability, transport and translation. Dysfunction in any of these processes, often caused by mutations in the coding and non--‐ coding RNAs, can be very destructive to

Purinergic Signalling and the Nervous System

Purinergic Signalling and the Nervous System
  • Author : Geoffrey Burnstock,Verkhratsky Alexei
  • Publisher : Springer Science & Business Media
  • Release : 05 June 2012
GET THIS BOOKPurinergic Signalling and the Nervous System

In the first 20 years that followed the purinergic signalling hypothesis in 1972, most scientists were sceptical about its validity, largely because ATP was so well established as an intracellular molecule involved in cell biochemistry and it seemed unlikely that such a ubiquitous molecule would act as an extracellular signalling molecule. However, after the receptors for ATP and adenosine were cloned and characterized in the early 1990s and ATP was established as a synaptic transmitter in the brain and sympathetic ganglia, the

Methylxanthines

Methylxanthines
  • Author : Bertil B. Fredholm
  • Publisher : Springer Science & Business Media
  • Release : 22 September 2010
GET THIS BOOKMethylxanthines

In the present volume of the Handbook of Experimental Pharmacology well known experts describe the actions of different xanthines with a focus on caffeine and theophylline. A special chapter is devoted to theobromine, an active component of chocolate, the actions of which are less well characterized. This book also presents the pharmacology of one xanthine derivative, propentofylline, as an example of a xanthine that has gone through extensive development for a novel therapeutic area.