Advances in Nanomedicine for the Delivery of Therapeutic Nucleic Acids

Advances in Nanomedicine for the Delivery of Therapeutic Nucleic Acids addresses several issues related to safe and effective delivery of nucleic acids (NAs) using nanoparticles. A further emphasis would be laid on the mechanism of delivery of NAs, the barriers encountered and the strategies adapted to combat them. An exhaustive account of the advantages as well shortcomings of all the delivery vectors being employed in delivery of various NAs will be provided. On final note the regulatory aspects of nanoparticles mediated NA would be discussed, with focus on their clinical relevance. The design and development of nucleic acid-based therapeutics for the treatment of diseases arising from genetic abnormalities has made significant progress over the past few years. NAs have been widely explored for the treatment of cancer and infectious diseases or to block cell proliferation and thereby caused diseases. Advances in synthetic oligonucleotide chemistry resulted in synthesis of NAs that are relatively stable in in vivo environments. However, cellular targeting and intracellular delivery of NAs still remains a challenge. Further development of NA-based therapeutics depends on the progress of safe and effective carriers for systemic administration. Nanomedicine has facilitated availability of vectors with diminished cytotoxicity and enhanced efficacy which are rapidly emerging as systems of choice. These vectors protect NAs from enzymatic degradation by forming condensed complexes along with targeted tissue and cellular delivery. During the past few years, a myriad reports have appeared reporting delivery of NAs mediated by nanoparticles. This book will provide an overview of nanoparticles being employed in the in vitro and in vivo delivery of therapeutically relevant NAs like DNA, siRNA, LNA, PNA, etc. Provides a complete overview of the applicatiosn of nanomedicine in the delivery of nucleic acids, from characterization of nanoparticles, to in vitro and in vivo studies Discusses delivery issues of less well explored nucleic acids, like PNAs, Ribozymes, DNAzymes, etc. Summarizes the current state of research in nucleic acid delivery and underscores the future of nanomedicine in this field

Produk Detail:

  • Author : Surendra Nimesh
  • Publisher : Woodhead Publishing
  • Pages : 256 pages
  • ISBN : 0081005636
  • Rating : 4/5 from 21 reviews
CLICK HERE TO GET THIS BOOKAdvances in Nanomedicine for the Delivery of Therapeutic Nucleic Acids

Advances in Nanomedicine for the Delivery of Therapeutic Nucleic Acids

Advances in Nanomedicine for the Delivery of Therapeutic Nucleic Acids
  • Author : Surendra Nimesh,Ramesh Chandra,Nidhi Gupta
  • Publisher : Woodhead Publishing
  • Release : 04 April 2017
GET THIS BOOKAdvances in Nanomedicine for the Delivery of Therapeutic Nucleic Acids

Advances in Nanomedicine for the Delivery of Therapeutic Nucleic Acids addresses several issues related to safe and effective delivery of nucleic acids (NAs) using nanoparticles. A further emphasis would be laid on the mechanism of delivery of NAs, the barriers encountered and the strategies adapted to combat them. An exhaustive account of the advantages as well shortcomings of all the delivery vectors being employed in delivery of various NAs will be provided. On final note the regulatory aspects of nanoparticles

Nucleic Acids as Gene Anticancer Drug Delivery Therapy

Nucleic Acids as Gene Anticancer Drug Delivery Therapy
  • Author : Loutfy H. Madkour
  • Publisher : Academic Press
  • Release : 27 August 2019
GET THIS BOOKNucleic Acids as Gene Anticancer Drug Delivery Therapy

Nucleic Acids as Gene Anticancer Drug Delivery Therapy highlights the most recent developments in cancer treatment using nucleic acids, nanoparticles and polymer nanoparticles for genomic nanocarriers as drug delivery, including promising opportunities for targeted and combination therapy. The development of a wide spectrum of nanoscale technologies is beginning to change the scientific landscape in terms of disease diagnosis, treatment, and prevention. This book presents the use of nanotechnology for medical applications, focusing on its use for anticancer drug delivery. Various

Nucleic Acid Nanotheranostics

Nucleic Acid Nanotheranostics
  • Author : Marco Filice,Jesús Ruiz-Cabello
  • Publisher : Elsevier
  • Release : 26 February 2019
GET THIS BOOKNucleic Acid Nanotheranostics

Nucleic Acid Nanotheranostics: Biomedical Applications offers a comprehensive overview of improvements and new trends in fabrication of nanostructures as theranostic multifunctional carriers in gene therapy. With a strong focus on medical applications (comprising diagnosis, therapy and imaging), the book also examines gene therapy in an individual patient’s cells or tissues to treat genetic diseases. Sections cover Biomedical and Diagnostic applications of Nucleic Acids, Biologic and Synthetic Advanced Nanostructures for nucleic acid delivery, and important considerations of nanomedicine. This book

Nanostructures for the Engineering of Cells, Tissues and Organs

Nanostructures for the Engineering of Cells, Tissues and Organs
  • Author : Alexandru Mihai Grumezescu
  • Publisher : William Andrew
  • Release : 14 February 2018
GET THIS BOOKNanostructures for the Engineering of Cells, Tissues and Organs

Nanostructures for the Engineering of Cells: Tissues and Organs showcases recent advances in pharmaceutical nanotechnology, with particular emphasis on tissue engineering, organ and cell applications. The book provides an up-to-date overview of organ targeting and cell targeting using nanotechnology. In addition, tissue engineering applications, such as skin regeneration are also discussed. Written by a diverse range of international academics, this book is a valuable research resource for researchers working in the biomaterials, medical and pharmaceutical industries. Explains how nanomaterials regulate

Advanced Drug Delivery Systems in the Management of Cancer

Advanced Drug Delivery Systems in the Management of Cancer
  • Author : Kamal Dua,Meenu Mehta,Terezinha de Jesus Andreoli Pinto,Lisa G. Pont,Kylie A. Williams,Michael Rathbone
  • Publisher : Elsevier
  • Release : 24 June 2021
GET THIS BOOKAdvanced Drug Delivery Systems in the Management of Cancer

Advanced Drug Delivery Systems in the Management of Cancer discusses recent developments in nanomedicine and nano-based drug delivery systems used in the treatment of cancers affecting the blood, lungs, brain, and kidneys. The research presented in this book includes international collaborations in the area of novel drug delivery for the treatment of cancer. Cancer therapy remains one of the greatest challenges in modern medicine, as successful treatment requires the elimination of malignant cells that are closely related to normal cells

Nanotechnology in Biology and Medicine

Nanotechnology in Biology and Medicine
  • Author : Pradipta Ranjan Rauta,Yugal Kishore Mohanta,Debasis Nayak
  • Publisher : CRC Press
  • Release : 10 October 2019
GET THIS BOOKNanotechnology in Biology and Medicine

Nanotechnology in biology and medicine: Research advancements & future perspectives is focused to provide an interdisciplinary, integrative overview on the developments made in nanotechnology till date along with the ongoing trends and the future prospects. It presents the basics, fundamental results/current applications and latest achievements on nanobiotechnological researches worldwide scientific era. One of the major goals of this book is to highlight the multifaceted issues on or surrounding of nanotechnology on the basis of case studies, academic and theoretical articles,

RNA Nanotechnology

RNA Nanotechnology
  • Author : Bin Wang
  • Publisher : CRC Press
  • Release : 02 April 2014
GET THIS BOOKRNA Nanotechnology

In the past few decades there has been incredible growth in "bionano"-related research, which has been accompanied by numerous publications in this field. Although various compilations address topics related to deoxyribonucleic acid (DNA) and protein, there are few books that focus on determining the structure of ribonucleic acid (RNA) and using RNA as building blocks to construct nanoarchitectures for biomedical and healthcare applications. RNA Nanotechnology is a comprehensive volume that details both the traditional approaches and the latest developments

Nanotechnology Applications for Cancer Chemotherapy

Nanotechnology Applications for Cancer Chemotherapy
  • Author : Sanyog Jain,Kaisar Raza,Ashish Kumar Agrawal,Ankur Vaidya
  • Publisher : Elsevier
  • Release : 01 October 2020
GET THIS BOOKNanotechnology Applications for Cancer Chemotherapy

Applications of Nanotechnology in Cancer Chemotherapy offers a complete and concise summary of nanotechnological interventions for cancer management. It highlights the basics of oncology, the cancer microenvironment, targets for active drug delivery, the underlying mechanisms and molecular pathways to enhance the drug delivery to the cancer site. The book discusses the principles of basic and innovative nanocarrier-based therapeutic approaches to modulate the progression of the disease. In addition, this book also explores the evolving targeting approaches specific to the cancer

Role of Plant Growth Promoting Microorganisms in Sustainable Agriculture and Nanotechnology

Role of Plant Growth Promoting Microorganisms in Sustainable Agriculture and Nanotechnology
  • Author : Ajay Kumar,Amit Kishore Singh,Krishna Kumar Choudhary
  • Publisher : Woodhead Publishing
  • Release : 20 June 2019
GET THIS BOOKRole of Plant Growth Promoting Microorganisms in Sustainable Agriculture and Nanotechnology

Role of Plant Growth Promoting Microorganisms in Sustainable Agriculture and Nanotechnology explores PGPMs (actinomycetes, bacteria, fungi and cyanobacteria) and their multidimensional roles in agriculture, including their increasing applications in sustainable agriculture. In addition to their traditional understanding and applications in agriculture, PGPMs are increasingly known as a source of nano-particles production that are gaining significant interest in their ability to provide more economically, environmentally friendly and safe technologies to crop growers. The book considers new concepts and current developments in

Selected Papers from the 3rd European Congress on Imaging Infection and Inflammation

Selected Papers from the 3rd European Congress on Imaging Infection and Inflammation
  • Author : Alberto Signore,Luca Maria Sconfienza
  • Publisher : MDPI
  • Release : 07 December 2020
GET THIS BOOKSelected Papers from the 3rd European Congress on Imaging Infection and Inflammation

This Special Issue is a collection of selected papers from the 3rd European Congress on Imaging Infection and Inflammation (www.nuclearmedicinediscovery.org/events.asp) and results of consensus sessions by major experts in the field including Nuclear Medicine physicians, Radiologists, Clinicians and microbiologists. The Journal of Clinical Medicine (JCM) provides an opportunity to publish data that were presented and discussed at the meeting in Rome in December 2019. One of the extremely important missions of this meeting was to present the

Nano-Pharmacokinetics and Theranostics

Nano-Pharmacokinetics and Theranostics
  • Author : Nanasaheb D. Thorat,Nitesh Kumar
  • Publisher : Academic Press
  • Release : 09 August 2021
GET THIS BOOKNano-Pharmacokinetics and Theranostics

Nano-Pharmacokinetics and Theranostics: Advancing Cancer Therapy addresses from a comprehensive and multidisciplinary approach the translational aspects and clinical perspectives of nano-pharmacokinetics using cancer as a model disease. Nano-pharmacokinetics is emerging as an important sub discipline of nanoscience and medical sciences because of the increasing safety issues of nanosystems on living organisms. This book reports the dynamics of nanosystems in living organisms for better understanding of nanotoxicity, pharmacology, biochemistry, physiology and medicine perspectives. It further examines current progress of state-of-the art

Nucleic Acids Chemistry

Nucleic Acids Chemistry
  • Author : Ramon Eritja
  • Publisher : Walter de Gruyter GmbH & Co KG
  • Release : 18 January 2021
GET THIS BOOKNucleic Acids Chemistry

This book compiles recent research on the modification of nucleic acids. It covers backbone modifications and conjugation of lipids, peptides and proteins to oligonucleotides and their therapeutic use. Synthesis and application in biomedicine and nanotechnology of aptamers, fluorescent and xeno nucleic acids, DNA repair and artificial DNA are discussed as well.

Polymer Science and Nanotechnology

Polymer Science and Nanotechnology
  • Author : Ravin Narain
  • Publisher : Elsevier
  • Release : 16 June 2020
GET THIS BOOKPolymer Science and Nanotechnology

Polymer Science and Nanotechnology: Fundamentals and Applications brings together the latest advances in polymer science and nanoscience. Sections explain the fundamentals of polymer science, including key aspects and methods in terms of molecular structure, synthesis, characterization, microstructure, phase structure and processing and properties before discussing the materials of particular interest and utility for novel applications, such as hydrogels, natural polymers, smart polymers and polymeric biomaterials. The second part of the book examines essential techniques in nanotechnology, with an emphasis on

Nanocatalysis

Nanocatalysis
  • Author : Vanesa Calvino-Casilda,Antonio José López-Peinado,Rosa María Martín-Aranda,Elena Pérez Mayoral
  • Publisher : CRC Press
  • Release : 14 February 2019
GET THIS BOOKNanocatalysis

Synthesis and design of new nanocatalysts is an important area of research that aims to introduce multiple types of useful applications in a greener market. The necessity of nanostructuring the active sites has emerged as the key point in a successful design of the catalysts. The book covers the progress in this research area done in the last ten years. It includes the classification of catalysts and structure of active sites at the nanoscale. The book covers examples to present