Alpha glucosidase Inhibitors

Alpha-glucosidase Inhibitors: Clinically Promising Candidates for Anti-diabetic Drug Discovery presents information that researchers can use to address a whole host of promising leads for the development of novel, oral, anti-diabetic drugs with improved efficacy and fewer side effects. Beginning with a discussion of the huge potential of α -glucosidase inhibitor leads and adaptations, and highlighting their importance within the field of anti-diabetic drug discovery, the book provides chemical structures, detailed background information and in vivo and in vitro biological activity data, and more economical adaptations of these structures. Drawing on the author’s expert research in the field, this book highlights promising leads for development and helps researchers select the most appropriate inhibitors for their own work. It is a useful tool not only for anti-diabetic drug development researchers, but also for those whose research may be enhanced by an understanding of α -glucosidase inhibitor chemistry and activity. Identifies and presents promising α-glucosidase inhibitors of natural and synthetic origin that belong to a variety of chemical classes Compiles chemical structures and detailed in vivo and in vitro biological activity data that will help researchers select inhibitors for further work Discusses promising avenues and potential challenges in the development of new α-glucosidase inhibitors based on their activity data

Produk Detail:

  • Author : Usman Ghani
  • Publisher : Elsevier
  • Pages : 242 pages
  • ISBN : 0081026285
  • Rating : 4/5 from 21 reviews
CLICK HERE TO GET THIS BOOKAlpha glucosidase Inhibitors

Alpha-glucosidase Inhibitors

Alpha-glucosidase Inhibitors
  • Author : Usman Ghani
  • Publisher : Elsevier
  • Release : 19 November 2019
GET THIS BOOKAlpha-glucosidase Inhibitors

Alpha-glucosidase Inhibitors: Clinically Promising Candidates for Anti-diabetic Drug Discovery presents information that researchers can use to address a whole host of promising leads for the development of novel, oral, anti-diabetic drugs with improved efficacy and fewer side effects. Beginning with a discussion of the huge potential of α -glucosidase inhibitor leads and adaptations, and highlighting their importance within the field of anti-diabetic drug discovery, the book provides chemical structures, detailed background information and in vivo and in vitro biological activity data,

Oral Antidiabetics

Oral Antidiabetics
  • Author : Jochen Kuhlmann,Walter Puls
  • Publisher : Springer Science & Business Media
  • Release : 11 November 2013
GET THIS BOOKOral Antidiabetics

Diabetes continues to spread worldwide. Traditionally diabetes in adults has not been considered a serious life-threatening disease. This attitude needs to be changed, however, since the complications associated with the adult form of diabetes affect almost every organ system. The high morbidity and mortality of Non-Insulin-Dependent Diabetes Mellitus (NIDDM) suggest that current treatment strategies are unsatisfactory, pointing to an urgent need for new therapeutic approaches. This volume provides a comprehensive description and evaluation of recently obtained and previously unpublished data

Systematic Reviews in Health Care

Systematic Reviews in Health Care
  • Author : Matthias Egger,George Davey-Smith,Douglas Altman
  • Publisher : John Wiley & Sons
  • Release : 01 July 2013
GET THIS BOOKSystematic Reviews in Health Care

The second edition of this best-selling book has been thoroughly revised and expanded to reflect the significant changes and advances made in systematic reviewing. New features include discussion on the rationale, meta-analyses of prognostic and diagnostic studies and software, and the use of systematic reviews in practice.

Nutritional and Therapeutic Interventions for Diabetes and Metabolic Syndrome

Nutritional and Therapeutic Interventions for Diabetes and Metabolic Syndrome
  • Author : Debasis Bagchi,Sreejayan Nair
  • Publisher : Academic Press
  • Release : 25 January 2012
GET THIS BOOKNutritional and Therapeutic Interventions for Diabetes and Metabolic Syndrome

Diabetes mellitus affects approximately 20 million people in the US, or nearly 7% of the population. It is expected to increase by 70% within the next 25 years, and numerous epidemiologic studies have demonstrated that type 2 diabetes increases the risk of cardiovascular morbidity and mortality. It is estimated to cost over $92 billion in health care costs and lost productivity. The increased risk is due to the detrimental vascular effects of prolonged exposure to a hyperglycemic, oxidant-rich environment yielding associated cardiovascular risk factors: atherosclerosis, hypertension

Novelties in Diabetes

Novelties in Diabetes
  • Author : C. Stettler,E. Christ,P. Diem
  • Publisher : Karger Medical and Scientific Publishers
  • Release : 27 January 2016
GET THIS BOOKNovelties in Diabetes

The field of diabetes mellitus research is currently characterized by rapid and remarkable growth that has led to the development of significant diagnostic and therapeutic advances. This is very important given the fact that the frequency of the disease continues to increase at alarming rates worldwide. This new volume is a comprehensive overview of the contemporary state of the art in the field. Experts shed light on a broad range of relevant aspects, from genetic background to topics related to

Medicinal Foods as Potential Therapies for Type-2 Diabetes and Associated Diseases

Medicinal Foods as Potential Therapies for Type-2 Diabetes and Associated Diseases
  • Author : Solomon Habtemariam
  • Publisher : Academic Press
  • Release : 08 June 2019
GET THIS BOOKMedicinal Foods as Potential Therapies for Type-2 Diabetes and Associated Diseases

Medicinal Foods as Potential Therapies for Type-2 Diabetes and Associated Diseases: The Chemical and Pharmacological Basis of their Action focuses on active pharmacological principles that modulate diabetes, associated risk factors, complications and the mechanism of action of widely used anti-diabetic herbal plants—rather than just the nutritional composition of certain foods. The book provides up-to-date information on acclaimed antidiabetic super fruits, spices and other food ingredients. Sections cover diabetes and obesity at the global level, the physiological control of carbohydrate

Drug Concentration Monitoring Microbial Alpha-Glucosidase Inhibitors Plasminogen Activators

Drug Concentration Monitoring Microbial Alpha-Glucosidase Inhibitors Plasminogen Activators
  • Author : Anonim
  • Publisher : Springer Science & Business Media
  • Release : 06 December 2012
GET THIS BOOKDrug Concentration Monitoring Microbial Alpha-Glucosidase Inhibitors Plasminogen Activators

Das Buch enthlt Kapitel ber: M.B. Bottorff, W.E. Evans, Memphis, TN, USA: berwachung der Medikament-KonzentrationE. Truscheit, I. Hillebrand, B. Junge, L. Mller, W. Puls, D.D. Schmidt, Wuppertal, FRG: Inhibitoren der mikrobiellen alpha-Glucosidase: Chemie, Biochemie und potentielle therapeutische AnwendungenH. Will, Berlin-Buch, GDR: Plasminogen-Aktivatoren: Molekleigenschaften, biologische Zellfunktion und klinische Anwendung.

The Diabetes Textbook

The Diabetes Textbook
  • Author : Joel Rodriguez-Saldana
  • Publisher : Springer
  • Release : 27 June 2019
GET THIS BOOKThe Diabetes Textbook

Diabetes has become a worldwide health problem, the global estimated prevalence approaches ten percent and the burden of this disease in terms of morbidity and mortality is unprecedented. The advances acquired through the knowledge of the mechanisms of the disease and the variety of therapeutic approaches contrast with the inability of private and public health systems in underdeveloped and even developed countries to achieve the goals of treatment. This paradox has been described in many sources: the surge of scientific

Pharmacotherapy of Diabetes: New Developments

Pharmacotherapy of Diabetes: New Developments
  • Author : Carl Erik Mogensen
  • Publisher : Springer Science & Business Media
  • Release : 23 October 2007
GET THIS BOOKPharmacotherapy of Diabetes: New Developments

Diabetes is a huge and growing healthcare worry, especially in Western countries. The treatment of both types – 1 and 2 – of this disease has changed radically over the past few years. This work provides an overview of all the changes that will come to be implemented in clinical practice. Summarizing all aspects of treatment, this book delineates the large amount of research work that has been completed over the last few years into the relief of complications in diabetes and vascular medicine

Discovery and Development of Antidiabetic Agents from Natural Products

Discovery and Development of Antidiabetic Agents from Natural Products
  • Author : Goutam Brahmachari
  • Publisher : Elsevier
  • Release : 11 October 2016
GET THIS BOOKDiscovery and Development of Antidiabetic Agents from Natural Products

Discovery and Development of Antidiabetic Agents from Natural Products brings together global research on the medicinal chemistry of active agents from natural sources for the prevention and treatment of diabetes and associated disorders. From the identification of promising leads, to the extraction and synthesis of bioactive molecules, this book explores a range of important topics to support chemists in the discovery and development of safer, more economical therapeutics that are desperately needed in response to this emerging global epidemic. Beginning

Davis's Drug Guide for Rehabilitation Professionals

Davis's Drug Guide for Rehabilitation Professionals
  • Author : Charles D Ciccone
  • Publisher : F.A. Davis
  • Release : 21 March 2013
GET THIS BOOKDavis's Drug Guide for Rehabilitation Professionals

A one-of-a-kind guide specifically for rehabilitation specialists! A leader in pharmacology and rehabilitation, Charles Ciccone, PT, PhD offers a concise, easy-to-access resource that delivers the drug information rehabilitation specialists need to know. Organized alphabetically by generic name, over 800 drug monographs offer the most up-to-date information on drug indications, therapeutic effects, potential adverse reactions, and much more! A list of implications for physical therapy at the end of each monograph helps you provide the best possible care for your patients. It’

Treatment of Type 2 Diabetes

Treatment of Type 2 Diabetes
  • Author : Colleen Croniger
  • Publisher : BoD – Books on Demand
  • Release : 01 April 2015
GET THIS BOOKTreatment of Type 2 Diabetes

Obesity and type 2 diabetes are increasing worldwide problems. In this book we reviewed factors that contribute to glucose homeostasis and the pathogenesis of Type 2 diabetes. In addition the book addresses current strategies for treatment of Type 2 Diabetes.

Churchill's Pocketbook of Diabetes E-Book

Churchill's Pocketbook of Diabetes E-Book
  • Author : Sujoy Ghosh,Andrew Collier
  • Publisher : Elsevier Health Sciences
  • Release : 16 July 2012
GET THIS BOOKChurchill's Pocketbook of Diabetes E-Book

The incidence of diabetes is increasing at epidemic proportions worldwide, presenting a huge challenge to modern medicine. In response, scientific advances in the understanding of diabetes and its complications are being translated into improved clinical practice at ever faster rates. Greater understanding of aetiopathogenesis of the different types of diabetes, the emerging roles of novel pharmacological agents and the importance placed on multidisciplinary team working and multi-risk-factor treatment all contribute to this. Now in a fully revised second edition, this

Iminosugars with Endoplasmic Reticulum Alpha-glucosidase Inhibitor Activity are Potent Inhibitors of Zika Virus Replication in Vitro

Iminosugars with Endoplasmic Reticulum Alpha-glucosidase Inhibitor Activity are Potent Inhibitors of Zika Virus Replication in Vitro
  • Author : Gitanjali L Bhushan
  • Publisher : Unknown Publisher
  • Release : 16 April 2021
GET THIS BOOKIminosugars with Endoplasmic Reticulum Alpha-glucosidase Inhibitor Activity are Potent Inhibitors of Zika Virus Replication in Vitro

Zika virus (ZIKV) is a vector-borne virus of the family Flaviviridae, which continues to spread and remains a major global public health threat. Currently, there are no approved vaccines or antivirals against ZIKV. In this study, the anti-ZIKV ability of four iminosugars with endoplasmic reticulum - glucosidase inhibitor (ER-AGI) activity namely, deoxynojirimycin (DNJ), N-nonyl deoxynojirimycin (NN-DNJ), castanospermine and celgosivir were investigated. None of the four ER-AGIs showed any significant (p>0.05) cytotoxicity in Vero and human microglia (CHME-3) cells from 0.01 M