Annotating New Genes

In recent years, a number of academic and commercial software packages and databases have been developed for the analysis and screening of biological data; however, the usability of these data is compromised by so-called novel genes to which no biological function is assigned. Annotating new genes outlines an approach to the analysis of evolutionary-conserved, heart-enriched genes with unknown functions, offering a step-by-step description of the procedure from screening to validation. The book begins by offering an introduction to the databases and software available, before moving on to cover programming guidelines, including a specific case study on the use of C-It for in silico screening. The second half of the book offers a step-by-step guide to experimental validation concepts and procedures, as well as an overview of additional potential applications of this approach in the field of stem cells and tissue regeneration, before a concluding chapter summarises the concepts and theories presented. Focuses not only on screening but also on biological validations Provides details of databases and software (web interface) products for biologists with minimal computation skills Offers a step-by-step outline of the procedure involved

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  • Author : Shizuka Uchida
  • Publisher : Elsevier
  • Pages : 196 pages
  • ISBN : 1908818123
  • Rating : 4/5 from 21 reviews
CLICK HERE TO GET THIS BOOKAnnotating New Genes

Annotating New Genes

Annotating New Genes
  • Author : Shizuka Uchida
  • Publisher : Elsevier
  • Release : 06 August 2012
GET THIS BOOKAnnotating New Genes

In recent years, a number of academic and commercial software packages and databases have been developed for the analysis and screening of biological data; however, the usability of these data is compromised by so-called novel genes to which no biological function is assigned. Annotating new genes outlines an approach to the analysis of evolutionary-conserved, heart-enriched genes with unknown functions, offering a step-by-step description of the procedure from screening to validation. The book begins by offering an introduction to the databases

Genome Annotation

Genome Annotation
  • Author : Jung Soh,Paul M.K. Gordon,Christoph W. Sensen
  • Publisher : CRC Press
  • Release : 19 April 2016
GET THIS BOOKGenome Annotation

The success of individualized medicine, advanced crops, and new and sustainable energy sources requires thoroughly annotated genomic information and the integration of this information into a coherent model. A thorough overview of this field, Genome Annotation explores automated genome analysis and annotation from its origins to the challenges of next-generation sequencing data analysis. The book initially takes you through the last 16 years since the sequencing of the first complete microbial genome. It explains how current analysis strategies were developed, including

Modern Genome Annotation

Modern Genome Annotation
  • Author : D. Frishman,Alfonso Valencia
  • Publisher : Springer Science & Business Media
  • Release : 02 October 2009
GET THIS BOOKModern Genome Annotation

An accurate description of current scientific developments in the field of bioinformatics and computational implementation is presented by research of the BioSapiens Network of Excellence. Bioinformatics is essential for annotating the structure and function of genes, proteins and the analysis of complete genomes and to molecular biology and biochemistry. Included is an overview of bioinformatics, the full spectrum of genome annotation approaches including; genome analysis and gene prediction, gene regulation analysis and expression, genome variation and QTL analysis, large scale

Bioinformatics and Functional Genomics

Bioinformatics and Functional Genomics
  • Author : Jonathan Pevsner
  • Publisher : John Wiley & Sons
  • Release : 04 March 2005
GET THIS BOOKBioinformatics and Functional Genomics

Wiley is proud to announce the publication of the first ever broad-based textbook introduction to Bioinformatics and Functional Genomics by a trained biologist, experienced researcher, and award-winning instructor. In this new text, author Jonathan Pevsner, winner of the 2001 Johns Hopkins University "Teacher of the Year" award, explains problem-solving using bioinformatic approaches using real examples such as breast cancer, HIV-1, and retinal-binding protein throughout. His book includes 375 figures and over 170 tables. Each chapter includes: Problems, discussion of Pitfalls, Boxes explaining key

Gene Prediction

Gene Prediction
  • Author : Martin Kollmar
  • Publisher : Humana Press
  • Release : 19 May 2019
GET THIS BOOKGene Prediction

This volume introduces software used for gene prediction with focus on eukaryotic genomes. The chapters in this book describe software and web server usage as applied in common use-cases, and explain ways to simplify re-annotation of long available genome assemblies. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary computational requirements, step-by-step, readily reproducible computational protocols, and tips on troubleshooting and avoiding known pitfalls. Cutting-edge and thorough,

Modern Genome Annotation

Modern Genome Annotation
  • Author : D. Frishman,Alfonso Valencia
  • Publisher : Springer Science & Business Media
  • Release : 02 October 2009
GET THIS BOOKModern Genome Annotation

An accurate description of current scientific developments in the field of bioinformatics and computational implementation is presented by research of the BioSapiens Network of Excellence. Bioinformatics is essential for annotating the structure and function of genes, proteins and the analysis of complete genomes and to molecular biology and biochemistry. Included is an overview of bioinformatics, the full spectrum of genome annotation approaches including; genome analysis and gene prediction, gene regulation analysis and expression, genome variation and QTL analysis, large scale

Genome Annotation

Genome Annotation
  • Author : Jung Soh,Paul M.K. Gordon,Christoph W. Sensen
  • Publisher : CRC Press
  • Release : 19 April 2016
GET THIS BOOKGenome Annotation

The success of individualized medicine, advanced crops, and new and sustainable energy sources requires thoroughly annotated genomic information and the integration of this information into a coherent model. A thorough overview of this field, Genome Annotation explores automated genome analysis and annotation from its origins to the challenges of next-generation sequencing data analysis. The book initially takes you through the last 16 years since the sequencing of the first complete microbial genome. It explains how current analysis strategies were developed, including

The Grape Genome

The Grape Genome
  • Author : Dario Cantu,M. Andrew Walker
  • Publisher : Springer Nature
  • Release : 13 November 2019
GET THIS BOOKThe Grape Genome

This book describes the current state of international grape genomics, with a focus on the latest findings, tools and strategies employed in genome sequencing and analysis, and genetic mapping of important agronomic traits. It also discusses how these are having a direct impact on outcomes for grape breeders and the international grape research community. While V. vinifera is a model species, it is not always appreciated that its cultivation usually requires the use of other Vitis species as rootstocks. The

Pacific Symposium on Biocomputing 2007

Pacific Symposium on Biocomputing 2007
  • Author : Russ Altman
  • Publisher : World Scientific
  • Release : 22 January 2021
GET THIS BOOKPacific Symposium on Biocomputing 2007

The Pacific Symposium on Biocomputing (PSB) 2007 is an international, multidisciplinary conference for the presentation and discussion of current research in the theory and application of computational methods in problems of biological significance. Presentations are rigorously peer reviewed and are published in an archival proceedings volume. PSB 2007 will be held January 3OCo7, 2007 at the Grand Wailea, Maui. Tutorials will be offered prior to the start of the conference. PSB 2007 will bring together top researchers from the US, the Asian Pacific nations,

Sequence — Evolution — Function

Sequence — Evolution — Function
  • Author : Eugene V. Koonin,Michael Galperin
  • Publisher : Springer Science & Business Media
  • Release : 29 June 2013
GET THIS BOOKSequence — Evolution — Function

Sequence - Evolution - Function is an introduction to the computational approaches that play a critical role in the emerging new branch of biology known as functional genomics. The book provides the reader with an understanding of the principles and approaches of functional genomics and of the potential and limitations of computational and experimental approaches to genome analysis. Sequence - Evolution - Function should help bridge the "digital divide" between biologists and computer scientists, allowing biologists to better grasp the

Assessing Rare Variation in Complex Traits

Assessing Rare Variation in Complex Traits
  • Author : Eleftheria Zeggini,Andrew Morris
  • Publisher : Springer
  • Release : 13 August 2015
GET THIS BOOKAssessing Rare Variation in Complex Traits

This book is unique in covering a wide range of design and analysis issues in genetic studies of rare variants, taking advantage of collaboration of the editors with many experts in the field through large-scale international consortia including the UK10K Project, GO-T2D and T2D-GENES. Chapters provide details of state-of-the-art methodology for rare variant detection and calling, imputation and analysis in samples of unrelated individuals and families. The book also covers analytical issues associated with the study of

Bioinformatics in Aquaculture

Bioinformatics in Aquaculture
  • Author : Zhanjiang (John) Liu
  • Publisher : John Wiley & Sons
  • Release : 17 April 2017
GET THIS BOOKBioinformatics in Aquaculture

Bioinformatics derives knowledge from computer analysis of biological data. In particular, genomic and transcriptomic datasets are processed, analysed and, whenever possible, associated with experimental results from various sources, to draw structural, organizational, and functional information relevant to biology. Research in bioinformatics includes method development for storage, retrieval, and analysis of the data. Bioinformatics in Aquaculture provides the most up to date reviews of next generation sequencing technologies, their applications in aquaculture, and principles and methodologies for the analysis of genomic

The Gene Ontology Handbook

The Gene Ontology Handbook
  • Author : Christophe Dessimoz,Nives Skunca
  • Publisher : Unknown Publisher
  • Release : 08 October 2020
GET THIS BOOKThe Gene Ontology Handbook

This book provides a practical and self-contained overview of the Gene Ontology (GO), the leading project to organize biological knowledge on genes and their products across genomic resources. Written for biologists and bioinformaticians, it covers the state-of-the-art of how GO annotations are made, how they are evaluated, and what sort of analyses can and cannot be done with the GO. In the spirit of the Methods in Molecular Biology book series, there is an emphasis throughout the chapters on providing

Rice Biology in the Genomics Era

Rice Biology in the Genomics Era
  • Author : Hiro-Yuki Hirano,Atshushi Hirai,Yoshio Sano,Takuji Sasaki
  • Publisher : Springer Science & Business Media
  • Release : 08 January 2008
GET THIS BOOKRice Biology in the Genomics Era

There are few more emotive, or important, crops in the world than rice – the staple food for a huge proportion of the world’s population. This volume presents the latest results of research in crop improvement as well as in molecular and cellular activities in rice. It consists of 26 chapters and is divided into the following four sections: Genome-wide and genome-based research; Signal transduction and development; Evolution and ecology; Improvement of rice.