Antifungal Compounds Discovery

Fungi are both the cause of many major health problems and an incredible source of compounds for developing new medicinal treatments, and with the increasing emergence of multidrug resistance, the need for new antimicrobial agents is greater than ever. Antifungal Compound Discovery provides researchers with a detailed study of both natural and synthetic compounds that can be effective against a variety of fungal species, supporting and encouraging the design of innovative, potent new drug candidates for the treatment of fungal infections. Beginning with an introduction to both the history and latest developments in this field, the book goes on to provide helpful background information on key fungal species before outlining current antifungal therapies and reasons further development is needed. Detailed chapters then follow reviewing a broad range of natural and synthetic antifungal agents, and discussing the synergistic effect of working with both simultaneously. Finally, the book concludes by considering potential future developments in this important field. Supported with detailed schemes and key information on the biological activity of all selected compounds, Antifungal Compound Discovery is a comprehensive guide helping researchers understand the relationship between specific chemicals structures and their antifungal potency, and a key tool for all those involved in the identification and development of antimicrobial compounds. Provides an overview of the most specific mycotic infections and fungal species as background for compound development Presents the chemical formulas of all natural and synthetic compounds reviewed Combines detailed information about origin, isolation and possible therapeutic uses of all indexed compounds, including biological activity, mechanism of action and SAR information

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  • Author : Marina Sokovic
  • Publisher : Elsevier
  • Pages : 290 pages
  • ISBN : 0128158255
  • Rating : 4/5 from 21 reviews
CLICK HERE TO GET THIS BOOKAntifungal Compounds Discovery

Antifungal Compounds Discovery

Antifungal Compounds Discovery
  • Author : Marina Sokovic,Konstantinos Liaras
  • Publisher : Elsevier
  • Release : 30 September 2020
GET THIS BOOKAntifungal Compounds Discovery

Fungi are both the cause of many major health problems and an incredible source of compounds for developing new medicinal treatments, and with the increasing emergence of multidrug resistance, the need for new antimicrobial agents is greater than ever. Antifungal Compound Discovery provides researchers with a detailed study of both natural and synthetic compounds that can be effective against a variety of fungal species, supporting and encouraging the design of innovative, potent new drug candidates for the treatment of fungal

Antifungal Agents

Antifungal Agents
  • Author : G. K. Dixon,Leonard G. Copping,Derek W. Hollomon
  • Publisher : Bios Scientific Pub Limited
  • Release : 16 April 1995
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Explores how new molecular technologies are interfacing with chemistry and biology in the search for new fungicide targets.

Antifungal Drug Discovery: New Theories and New Therapies

Antifungal Drug Discovery: New Theories and New Therapies
  • Author : Chaminda Jayampath Seneviratne,Edvaldo Antonio Ribeiro Rosa
  • Publisher : Frontiers Media SA
  • Release : 13 September 2016
GET THIS BOOKAntifungal Drug Discovery: New Theories and New Therapies

Fungal infections such as candidoses can range from superficial mucous membrane infection to life-threatening systemic mycoses. Candida infections are a significant clinical problem globally due to rapid rise in compromised host populations including HIV/AIDS, organ transplant recipients and patients on chemotherapy. In addition, sharp increase in aging populations which are susceptible to fungal infections is expected in next few decades. Antifungal drugs are relatively difficult to develop compared to the antibacterial drugs owing to the eukaryotic nature of the

Antifungal Therapy

Antifungal Therapy
  • Author : Mahmoud A. Ghannoum, PhD, EMBA,Mahmoud A. Ghannoum,John R. Perfect,John R. Perfect, MD
  • Publisher : CRC Press
  • Release : 19 April 2016
GET THIS BOOKAntifungal Therapy

A concise one-stop-practical reference for the various physicians dealing with fungal infections, Antifungal Therapy appeals to infectious disease physicians, transplant surgeons, dermatologists, and intensivists, as well as basic scientists and pharmaceutical company researchers interested in the state of antifungal therapy. This book provides a comprehensive, up-to-date overview of the pertinent issues pertaining to antifungal treatment. Divided into four interrelated sections for a cohesive discussion covers: history of antifungals from the discovery of the polyenes to the echinocandins antifungal susceptibility methods

Antimicrobial Drug Discovery

Antimicrobial Drug Discovery
  • Author : George Tegos,Eleftherios Mylonakis
  • Publisher : CABI
  • Release : 16 April 2021
GET THIS BOOKAntimicrobial Drug Discovery

Resistance is on the rise among a variety of human pathogenic microorganisms associated with common and potentially life-threatening infections, including penicillin-resistant Streptococcus pneumonia and Methicillin-resistant Staphylococcus aureus (MRSA). There is increasing demand to approach the threat of multidrug resistance incorporating novel multidisciplinary methodologies and technological platforms. This book documents the latest research, covering current and promising activities in four key areas: computational chemistry and chemoinformatics, High Throughput Screening (HTS), non-vertebrate model hosts and light and nano-based technologies. It is essential

Fungicides

Fungicides
  • Author : Mizuho Nita
  • Publisher : BoD – Books on Demand
  • Release : 15 May 2013
GET THIS BOOKFungicides

This book comprised of three sections that focus various aspects of fungicide usages and its consequences. In the eight-chapter first section, authors discuss implementation of Integrated Plant Disease Management on a wide array of crops grown in different parts of the world: wheat productions in Argentina and in the US; corn, cotton and Eucalyptus productions in Brazil; rice productions in India; peanut productions in the southern US; and pine seedling nurseries in Serbia. The second section is composed of two

Anticandidal Agents

Anticandidal Agents
  • Author : Awanish Kumar
  • Publisher : Academic Press
  • Release : 12 September 2016
GET THIS BOOKAnticandidal Agents

Anticandidal Agents provides the latest information on candida drug resistance and its remedial implications. In this compilation, users will find a comprehensive view on overcoming resistance in anticandidal drugs, along with information on novel molecules. Candida albicans is an opportunistic pathogenic fungus responsible for life threating invasive and nosocomial infections across the globe. Candidiasis is a major cause of morbidity among immunocompromised patients. Infections caused by non-albicans candida like C. glabrata, C. parapsilosis, and C. tropicalis have also imposed a

Discovery of Novel Natural Products with Therapeutic Potential

Discovery of Novel Natural Products with Therapeutic Potential
  • Author : Vincent P. Gullo
  • Publisher : Newnes
  • Release : 22 October 2013
GET THIS BOOKDiscovery of Novel Natural Products with Therapeutic Potential

Although science has discovered effective drugs for many of the diseases that afflict mankind, many human health problems remain untreatable. The search for novel therapeutic agents is always ongoing. This book will describe some of the diverse sources of natural products, such as terrestrial and marine environments; and will review how research has increased knowledge of biological systems and human disease, leading to the design of targeted asssays, amenable to high volume screening.

Biologically Active Natural Products

Biologically Active Natural Products
  • Author : Stephen J. Cutler,Horace G. Cutler
  • Publisher : CRC Press
  • Release : 27 July 1999
GET THIS BOOKBiologically Active Natural Products

Biologically Active Natural Products: Pharmaceuticals demonstrates the connections between agrochemicals and pharmaceuticals and explores the use of plants and plant products in the formulation and development of pharmaceuticals. Experts from around the world examine a multitude of topics, including evaluation of extracts from tropical plants for p

Antifungal Agents

Antifungal Agents
  • Author : Erika J. Ernst,P. David Rogers
  • Publisher : Springer Science & Business Media
  • Release : 16 April 2021
GET THIS BOOKAntifungal Agents

A collection of state-of-the-art molecular methods for studying antifungal resistance, for discovering and evaluating both new and existing antifungal drugs, and for understanding the host response and immunotherapy of such agents. The protocols follow the successful Methods in Molecular MedicineTM series format, each offering step-by-step laboratory instructions, an introduction outlining the principle behind the technique, lists of the necessary equipment and reagents, and tips on troubleshooting and avoiding known pitfalls.

Plant Bioactives and Drug Discovery

Plant Bioactives and Drug Discovery
  • Author : Valdir Cechinel-Filho
  • Publisher : John Wiley & Sons
  • Release : 11 April 2012
GET THIS BOOKPlant Bioactives and Drug Discovery

An in-depth exploration of the applications of plant bioactive metabolites in drug research and development Highlighting the complexity and applications of plant bioactive metabolites in organic and medicinal chemistry, Plant Bioactives and Drug Discovery: Principles, Practice, and Perspectives provides an in-depth overview of the ways in which plants can inform drug research and development. An edited volume featuring multidisciplinary international contributions from acclaimed scientists researching bioactive natural products, the book provides an incisive overview of one of the most important

Phytochemicals as Lead Compounds for New Drug Discovery

Phytochemicals as Lead Compounds for New Drug Discovery
  • Author : Chukwuebuka Egbuna,Shashank Kumar,Jonathan C. Ifemeje,Shahira M. Ezzat,Saravanan Kaliyaperumal
  • Publisher : Elsevier
  • Release : 07 September 2019
GET THIS BOOKPhytochemicals as Lead Compounds for New Drug Discovery

Phytochemicals as Lead Compounds for New Drug Discovery presents complete coverage of the recent advances in the discovery of phytochemicals from medicinal plants as models to the development of new drugs and chemical entities. Functional bioactive compounds of plant origin have been an invaluable source for many human therapeutic drugs and have played a major role in the treatment of diseases around the world. These compounds possess enormous structural and chemical diversity and have led to many important discoveries. This