Antifungal Compounds Discovery

Fungi are both the cause of many major health problems and an incredible source of compounds for developing new medicinal treatments, and with the increasing emergence of multidrug resistance, the need for new antimicrobial agents is greater than ever. Antifungal Compound Discovery provides researchers with a detailed study of both natural and synthetic compounds that can be effective against a variety of fungal species, supporting and encouraging the design of innovative, potent new drug candidates for the treatment of fungal infections. Beginning with an introduction to both the history and latest developments in this field, the book goes on to provide helpful background information on key fungal species before outlining current antifungal therapies and reasons further development is needed. Detailed chapters then follow reviewing a broad range of natural and synthetic antifungal agents, and discussing the synergistic effect of working with both simultaneously. Finally, the book concludes by considering potential future developments in this important field. Supported with detailed schemes and key information on the biological activity of all selected compounds, Antifungal Compound Discovery is a comprehensive guide helping researchers understand the relationship between specific chemicals structures and their antifungal potency, and a key tool for all those involved in the identification and development of antimicrobial compounds. Provides an overview of the most specific mycotic infections and fungal species as background for compound development Presents the chemical formulas of all natural and synthetic compounds reviewed Combines detailed information about origin, isolation and possible therapeutic uses of all indexed compounds, including biological activity, mechanism of action and SAR information

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  • Author : Marina Sokovic
  • Publisher : Elsevier
  • Pages : 290 pages
  • ISBN : 0128158255
  • Rating : 4/5 from 21 reviews
CLICK HERE TO GET THIS BOOKAntifungal Compounds Discovery

Antifungal Compounds Discovery

Antifungal Compounds Discovery
  • Author : Marina Sokovic,Konstantinos Liaras
  • Publisher : Elsevier
  • Release : 30 September 2020
GET THIS BOOKAntifungal Compounds Discovery

Fungi are both the cause of many major health problems and an incredible source of compounds for developing new medicinal treatments, and with the increasing emergence of multidrug resistance, the need for new antimicrobial agents is greater than ever. Antifungal Compound Discovery provides researchers with a detailed study of both natural and synthetic compounds that can be effective against a variety of fungal species, supporting and encouraging the design of innovative, potent new drug candidates for the treatment of fungal

Antifungal Drug Discovery: New Theories and New Therapies

Antifungal Drug Discovery: New Theories and New Therapies
  • Author : Chaminda Jayampath Seneviratne,Edvaldo Antonio Ribeiro Rosa
  • Publisher : Frontiers Media SA
  • Release : 13 September 2016
GET THIS BOOKAntifungal Drug Discovery: New Theories and New Therapies

Fungal infections such as candidoses can range from superficial mucous membrane infection to life-threatening systemic mycoses. Candida infections are a significant clinical problem globally due to rapid rise in compromised host populations including HIV/AIDS, organ transplant recipients and patients on chemotherapy. In addition, sharp increase in aging populations which are susceptible to fungal infections is expected in next few decades. Antifungal drugs are relatively difficult to develop compared to the antibacterial drugs owing to the eukaryotic nature of the

Antifungal Agents

Antifungal Agents
  • Author : G. K. Dixon,Leonard G. Copping,Derek W. Hollomon
  • Publisher : Bios Scientific Pub Limited
  • Release : 25 January 1995
GET THIS BOOKAntifungal Agents

Explores how new molecular technologies are interfacing with chemistry and biology in the search for new fungicide targets.

Antifungal Agents

Antifungal Agents
  • Author : Erika J. Ernst,P. David Rogers
  • Publisher : Springer Science & Business Media
  • Release : 25 January 2021
GET THIS BOOKAntifungal Agents

A collection of state-of-the-art molecular methods for studying antifungal resistance, for discovering and evaluating both new and existing antifungal drugs, and for understanding the host response and immunotherapy of such agents. The protocols follow the successful Methods in Molecular MedicineTM series format, each offering step-by-step laboratory instructions, an introduction outlining the principle behind the technique, lists of the necessary equipment and reagents, and tips on troubleshooting and avoiding known pitfalls.

Clinical Mycology

Clinical Mycology
  • Author : Elias J. Anaissie,Michael R. McGinnis,Michael A. Pfaller
  • Publisher : Elsevier Health Sciences
  • Release : 25 January 2021
GET THIS BOOKClinical Mycology

The first book of its kind to focus on the diagnosis, prevention, and treatment of patients with fungal infections, this definitive reference returns in a completely revised, full-color new edition. It presents specific recommendations for understanding, controlling, and preventing fungal infections based upon underlying principles of epidemiology and infection control policy, pathogenesis, immunology, histopathology, and laboratory diagnosis and antifungal therapy. More than 560 photographs, illustrations, and tables depict conditions as they appear in real life and equip you to identify clinical

Antimicrobial Drug Discovery

Antimicrobial Drug Discovery
  • Author : George Tegos,Eleftherios Mylonakis
  • Publisher : CABI
  • Release : 25 January 2021
GET THIS BOOKAntimicrobial Drug Discovery

Resistance is on the rise among a variety of human pathogenic microorganisms associated with common and potentially life-threatening infections, including penicillin-resistant Streptococcus pneumonia and Methicillin-resistant Staphylococcus aureus (MRSA). There is increasing demand to approach the threat of multidrug resistance incorporating novel multidisciplinary methodologies and technological platforms. This book documents the latest research, covering current and promising activities in four key areas: computational chemistry and chemoinformatics, High Throughput Screening (HTS), non-vertebrate model hosts and light and nano-based technologies. It is essential

Drug Discovery and Design

Drug Discovery and Design
  • Author : Anonim
  • Publisher : Elsevier
  • Release : 18 April 2001
GET THIS BOOKDrug Discovery and Design

Strategies to reduce medical uncertainty and build evidence have become critical to the advancement of medical knowledge and modern medical practice. As new techniques and strategies have arisen, so has the need for a current reference work. Drug Discovery and Design examines the latest research in the development of these new strategies. Some of the topics covered include angiotensin converting enzyme inhibitors, HIV protease inhibitors, PPAR agonists for diabetes, and glucan synthase antifungal agents.

Antifungal Therapy

Antifungal Therapy
  • Author : Mahmoud A. Ghannoum, PhD, EMBA,Mahmoud A. Ghannoum,John R. Perfect,John R. Perfect, MD
  • Publisher : CRC Press
  • Release : 19 April 2016
GET THIS BOOKAntifungal Therapy

A concise one-stop-practical reference for the various physicians dealing with fungal infections, Antifungal Therapy appeals to infectious disease physicians, transplant surgeons, dermatologists, and intensivists, as well as basic scientists and pharmaceutical company researchers interested in the state of antifungal therapy. This book provides a comprehensive, up-to-date overview of the pertinent issues pertaining to antifungal treatment. Divided into four interrelated sections for a cohesive discussion covers: history of antifungals from the discovery of the polyenes to the echinocandins antifungal susceptibility methods

Nitrogen, Phosphorus and Sulphur Utilisation by Fungi

Nitrogen, Phosphorus and Sulphur Utilisation by Fungi
  • Author : British Mycological Society. Symposium,R. Marchant
  • Publisher : Cambridge University Press
  • Release : 11 May 1989
GET THIS BOOKNitrogen, Phosphorus and Sulphur Utilisation by Fungi

The only up-to-date and detailed analysis of nitrogen, phosphorus and sulphur utilization by fungi is presented in this book. Based on the 1988 British Mycological Society symposium, it is broadly based, covering four basic areas: physiology and metabolism of nitrogen, phosphorus and sulphur by fungi; role of these minerals in pathogenic relationships with plants; their role in mutualistic relationships with plants; and the role of saprotrophic fungi in cycling of the elements through ecosystems. This is a useful reference for research

Drug Discovery from Nature

Drug Discovery from Nature
  • Author : S. Grabley,R. Thiericke
  • Publisher : Springer Science & Business Media
  • Release : 26 November 1998
GET THIS BOOKDrug Discovery from Nature

This book is unique in covering the present status and future potential of natural products in drug discovery. It provides readers with recent information regarding the impact on drug discovery, development and strategies, technical and automation aspects, and methods based on biochemistry as well as molecular biology, highlighting compounds from natural sources. Special emphasis is placed on the various strategies to gain access to natural compounds and combinatorial approaches by making use of both synthetic and biological methods.

Anticandidal Agents

Anticandidal Agents
  • Author : Awanish Kumar
  • Publisher : Academic Press
  • Release : 12 September 2016
GET THIS BOOKAnticandidal Agents

Anticandidal Agents provides the latest information on candida drug resistance and its remedial implications. In this compilation, users will find a comprehensive view on overcoming resistance in anticandidal drugs, along with information on novel molecules. Candida albicans is an opportunistic pathogenic fungus responsible for life threating invasive and nosocomial infections across the globe. Candidiasis is a major cause of morbidity among immunocompromised patients. Infections caused by non-albicans candida like C. glabrata, C. parapsilosis, and C. tropicalis have also imposed a

Plant Bioactives and Drug Discovery

Plant Bioactives and Drug Discovery
  • Author : Valdir Cechinel-Filho
  • Publisher : John Wiley & Sons
  • Release : 22 May 2012
GET THIS BOOKPlant Bioactives and Drug Discovery

An in-depth exploration of the applications of plant bioactive metabolites in drug research and development Highlighting the complexity and applications of plant bioactive metabolites in organic and medicinal chemistry, Plant Bioactives and Drug Discovery: Principles, Practice, and Perspectives provides an in-depth overview of the ways in which plants can inform drug research and development. An edited volume featuring multidisciplinary international contributions from acclaimed scientists researching bioactive natural products, the book provides an incisive overview of one of the most important

Bioactive Natural Products

Bioactive Natural Products
  • Author : Goutam Brahmachari
  • Publisher : John Wiley & Sons
  • Release : 20 January 2015
GET THIS BOOKBioactive Natural Products

Natural compounds, which have evolved their function over millions of years, are often more efficient than man-made compounds if a specific biological activity is needed, e.g. as an enzyme inhibitor or as a toxin to kill a cancer cell. This book comprising of sixteen technical chapters, highlights the chemical and biological aspects of potential natural products with an intention of unravelling their pharmaceutical applicability in modern drug discovery processes. Key features: Covers the synthesis, semi-synthesis and also biosynthesis of

Drug Discovery and Evaluation: Pharmacological Assays

Drug Discovery and Evaluation: Pharmacological Assays
  • Author : Hans Vogel
  • Publisher : Springer Science & Business Media
  • Release : 30 October 2007
GET THIS BOOKDrug Discovery and Evaluation: Pharmacological Assays

The new edition of this successful reference offers both cutting-edge and classic pharmacological methods. Thoroughly revised and expanded to two volumes, it offers an updated selection of the most frequently used assays for reliably detecting the pharmacological effects of potential drugs. Every chapter has been updated, and numerous assays have been added. Each of the more than 1,000 assays comprises a detailed protocol outlining purpose and rationale, and a critical assessment of the results and their pharmacological and clinical relevance.