Antifungal Compounds Discovery

Fungi are both the cause of many major health problems and an incredible source of compounds for developing new medicinal treatments, and with the increasing emergence of multidrug resistance, the need for new antimicrobial agents is greater than ever. Antifungal Compounds Discovery provides researchers with a detailed study of both natural and synthetic compounds that can be effective against a variety of fungal species, supporting and encouraging the design of innovative, potent new drug candidates for the treatment of fungal infections. Beginning with an introduction to both the history and latest developments in this field, the book goes on to provide helpful background information on key fungal species before outlining current antifungal therapies and reasons further development is needed. Detailed chapters then follow reviewing a broad range of natural and synthetic antifungal agents, and discussing the synergistic effect of working with both simultaneously. Finally, the book concludes by considering potential future developments in this important field. Supported with detailed schemes and key information on the biological activity of all selected compounds, Antifungal Compounds Discovery is a comprehensive guide helping researchers understand the relationship between specific chemical structures and their antifungal potency, and a key tool for all those involved in the identification and development of antimicrobial compounds. Provides an overview of the most specific mycotic infections and fungal species as background for compound development Presents the chemical formulas of all natural and synthetic compounds reviewed Combines detailed information about origin, isolation and possible therapeutic uses of all indexed compounds, including biological activity, mechanism of action and SAR information

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  • Author : Marina Sokovic
  • Publisher : Elsevier
  • Pages : 290 pages
  • ISBN : 0128158255
  • Rating : 4/5 from 21 reviews
CLICK HERE TO GET THIS BOOKAntifungal Compounds Discovery

Antifungal Compounds Discovery

Antifungal Compounds Discovery
  • Author : Marina Sokovic,Konstantinos Liaras
  • Publisher : Elsevier
  • Release : 18 September 2020
GET THIS BOOKAntifungal Compounds Discovery

Fungi are both the cause of many major health problems and an incredible source of compounds for developing new medicinal treatments, and with the increasing emergence of multidrug resistance, the need for new antimicrobial agents is greater than ever. Antifungal Compounds Discovery provides researchers with a detailed study of both natural and synthetic compounds that can be effective against a variety of fungal species, supporting and encouraging the design of innovative, potent new drug candidates for the treatment of fungal

Antifungal Drug Discovery: New Theories and New Therapies

Antifungal Drug Discovery: New Theories and New Therapies
  • Author : Chaminda Jayampath Seneviratne,Edvaldo Antonio Ribeiro Rosa
  • Publisher : Frontiers Media SA
  • Release : 13 September 2016
GET THIS BOOKAntifungal Drug Discovery: New Theories and New Therapies

Fungal infections such as candidoses can range from superficial mucous membrane infection to life-threatening systemic mycoses. Candida infections are a significant clinical problem globally due to rapid rise in compromised host populations including HIV/AIDS, organ transplant recipients and patients on chemotherapy. In addition, sharp increase in aging populations which are susceptible to fungal infections is expected in next few decades. Antifungal drugs are relatively difficult to develop compared to the antibacterial drugs owing to the eukaryotic nature of the

Antifungal Agents

Antifungal Agents
  • Author : G. K. Dixon,Leonard G. Copping,Derek W. Hollomon
  • Publisher : Bios Scientific Pub Limited
  • Release : 28 November 1995
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Explores how new molecular technologies are interfacing with chemistry and biology in the search for new fungicide targets.

Plant Bioactives and Drug Discovery

Plant Bioactives and Drug Discovery
  • Author : Valdir Cechinel-Filho
  • Publisher : John Wiley & Sons
  • Release : 11 April 2012
GET THIS BOOKPlant Bioactives and Drug Discovery

An in-depth exploration of the applications of plant bioactive metabolites in drug research and development Highlighting the complexity and applications of plant bioactive metabolites in organic and medicinal chemistry, Plant Bioactives and Drug Discovery: Principles, Practice, and Perspectives provides an in-depth overview of the ways in which plants can inform drug research and development. An edited volume featuring multidisciplinary international contributions from acclaimed scientists researching bioactive natural products, the book provides an incisive overview of one of the most important

Antifungal Therapy

Antifungal Therapy
  • Author : Mahmoud A. Ghannoum, PhD, EMBA,Mahmoud A. Ghannoum,John R. Perfect,John R. Perfect, MD
  • Publisher : CRC Press
  • Release : 19 April 2016
GET THIS BOOKAntifungal Therapy

A concise one-stop-practical reference for the various physicians dealing with fungal infections, Antifungal Therapy appeals to infectious disease physicians, transplant surgeons, dermatologists, and intensivists, as well as basic scientists and pharmaceutical company researchers interested in the state of antifungal therapy. This book provides a comprehensive, up-to-date overview of the pertinent issues pertaining to antifungal treatment. Divided into four interrelated sections for a cohesive discussion covers: history of antifungals from the discovery of the polyenes to the echinocandins antifungal susceptibility methods

Antimicrobial Drug Discovery

Antimicrobial Drug Discovery
  • Author : George Tegos,Eleftherios Mylonakis
  • Publisher : CABI
  • Release : 28 November 2021
GET THIS BOOKAntimicrobial Drug Discovery

Resistance is on the rise among a variety of human pathogenic microorganisms associated with common and potentially life-threatening infections, including penicillin-resistant Streptococcus pneumonia and Methicillin-resistant Staphylococcus aureus (MRSA). There is increasing demand to approach the threat of multidrug resistance incorporating novel multidisciplinary methodologies and technological platforms. This book documents the latest research, covering current and promising activities in four key areas: computational chemistry and chemoinformatics, High Throughput Screening (HTS), non-vertebrate model hosts and light and nano-based technologies. It is essential

Plant Bioactives and Drug Discovery

Plant Bioactives and Drug Discovery
  • Author : Valdir Cechinel-Filho
  • Publisher : John Wiley & Sons
  • Release : 22 May 2012
GET THIS BOOKPlant Bioactives and Drug Discovery

An in-depth exploration of the applications of plant bioactive metabolites in drug research and development Highlighting the complexity and applications of plant bioactive metabolites in organic and medicinal chemistry, Plant Bioactives and Drug Discovery: Principles, Practice, and Perspectives provides an in-depth overview of the ways in which plants can inform drug research and development. An edited volume featuring multidisciplinary international contributions from acclaimed scientists researching bioactive natural products, the book provides an incisive overview of one of the most important

Medicinal Plants

Medicinal Plants
  • Author : Bassam Hassan
  • Publisher : BoD – Books on Demand
  • Release : 25 March 2020
GET THIS BOOKMedicinal Plants

This book is focused on clarifying the anticancer effects (i.e., apoptotic, antiproliferative, antimetastatic, antiangiogenic) and mechanisms of most of the medicinal plants found in the world against solid and/or hematological cancers.

Validamycin and Its Derivatives

Validamycin and Its Derivatives
  • Author : Xiaolong Chen,Yuele Lu,Yongxian Fan,Yinchu Shen
  • Publisher : Elsevier
  • Release : 31 March 2017
GET THIS BOOKValidamycin and Its Derivatives

Validamycin and Its Derivatives: Discovery, Chemical Synthesis and Biological Activity presents, for the first time, a complete review of the underlying chemistry, synthesis, behavior and application of these compounds. Beginning with an introduction to validamycin, the book then outlines the key elements of its discovery and production, including details of its structures, isolation, analysis, and issues relating to its large scale production. Biological activities are then explored in more detail, followed by details of biosynthesis. Further to this, the chemical