Antimicrobial Peptides in Gastrointestinal Diseases

Antimicrobial peptides (AMPs), including cathelicidins and defensins are host defence peptides that carry out multiple roles in the gastrointestinal (GI) tract. Antimicrobial Peptides in Gastrointestinal Diseases presents knowledge about the physiological functions and pharmacological actions of AMPs in inflammation, cancer, and further infection of the GI tract. The book provides coverage from the basic research to clinical application for GI diseases. Current research and development of AMPs is presented, opening the way for further work on these peptides, not only in the context of GI diseases, but also for similar pathologies in other organs. AMPs are key to the regulation of human microbiome and second line defence in the GI mucosa, prevent colonization of pathogens and modulation of innate response to invading pathogens, and modify immunological reactions during inflammatory processes and oncogenic development in the GI mucosa. More importantly, AMPs possess diversified anti-microbial actions against various infectious diseases in the GI tract. With these physiological functions and pharmacological actions, AMPs have significant potential as therapeutic agents for the treatment of inflammation, cancer and further infection in the GI tract. Provides an overview of AMPs, particularly cathelicidin and defensin, in different diseases Covers inflammation and ulcer repair in the stomach and colon and carcinogenesis in the GI tract Presents AMP information and knowledge in a concise manner Gives useful information on all aspects of AMPs Promotes research on AMPs and their development as drugs, from bench, to clinical application

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  • Author : Chi Hin Cho
  • Publisher : Academic Press
  • Pages : 186 pages
  • ISBN : 0128143207
  • Rating : 4/5 from 21 reviews
CLICK HERE TO GET THIS BOOKAntimicrobial Peptides in Gastrointestinal Diseases

Antimicrobial Peptides in Gastrointestinal Diseases

Antimicrobial Peptides in Gastrointestinal Diseases
  • Author : Chi Hin Cho
  • Publisher : Academic Press
  • Release : 06 June 2018
GET THIS BOOKAntimicrobial Peptides in Gastrointestinal Diseases

Antimicrobial peptides (AMPs), including cathelicidins and defensins are host defence peptides that carry out multiple roles in the gastrointestinal (GI) tract. Antimicrobial Peptides in Gastrointestinal Diseases presents knowledge about the physiological functions and pharmacological actions of AMPs in inflammation, cancer, and further infection of the GI tract. The book provides coverage from the basic research to clinical application for GI diseases. Current research and development of AMPs is presented, opening the way for further work on these peptides, not only

Intestinal Immune System

Intestinal Immune System
  • Author : Soichiro Miura,Ryota Hokari
  • Publisher : Biota Publishing
  • Release : 01 August 2011
GET THIS BOOKIntestinal Immune System

In the intestine, a unique immunological system that is different from the systemic immune system exists to provide adaptive immunity in response to luminal bacteria and dietary antigens. There are many lymphoid cell aggregates called gut-associated lymphoid tissue (GALT) including Peyer’s patches (PPs), which function as important induction sites for the mucosal immune response. M-cells are present in the epithelium of PPs, having a specialized structure for uptake of macromolecules such as bacteria. In addition to GALT, there are

Nutraceutical Proteins and Peptides in Health and Disease

Nutraceutical Proteins and Peptides in Health and Disease
  • Author : Yoshinori Mine,Fereidoon Shahidi
  • Publisher : CRC Press
  • Release : 29 September 2005
GET THIS BOOKNutraceutical Proteins and Peptides in Health and Disease

Reports of the beneficial health effects of some peptides have begun to make their way into the scientific literature. Peptides can act as immunomodulators, and have been shown to have a positive influence on calcium absorption, and on regulation of serum cholesterol. A number of peptides may also possess antimicrobial properties that enhance the body's defense mechanisms, and others may produce inhibitory effects for angiotensin-I-converting enzyme (ACE), leading to novel treatments for blood pressure conditions, heart failure, and diabetes. Modern

Crohn's Disease and Ulcerative Colitis

Crohn's Disease and Ulcerative Colitis
  • Author : Daniel C. Baumgart
  • Publisher : Springer
  • Release : 01 March 2017
GET THIS BOOKCrohn's Disease and Ulcerative Colitis

This new edition is a unique combined resource for physicians and scientists addressing the needs of both groups. In addition to stimulating exchange and collaboration and shortening the path between discovery and application of new knowledge, the book helps clinicians understand new therapeutic concepts from their origins. The volume serves as a comprehensive guide to the current diagnostic modalities, including enhanced imaging techniques such as MRI and CT enterography, virtual colonoscopy, ultrasound, and endomicroscopy, as well as conventional and complex

Antimicrobial Peptides

Antimicrobial Peptides
  • Author : David A. Phoenix,Sarah R. Dennison,Frederick Harris
  • Publisher : John Wiley & Sons
  • Release : 27 December 2012
GET THIS BOOKAntimicrobial Peptides

In this text, the small team of expert authors presents the field in a comprehensive and accessible manner that is well suited for students and junior researchers. The result is a highly readable and systematically structured introduction to antimicrobial peptides, their structure, biological function and mode of action. The authors point the way towards a rational design of this potentially highly effective new class of clinical antibiotics on the brink of industrial application. They do this by discussing their design

Milk Proteins

Milk Proteins
  • Author : Isabel Gigli
  • Publisher : BoD – Books on Demand
  • Release : 07 September 2016
GET THIS BOOKMilk Proteins

Milk proteins have nutritional value and extraordinary biological properties. Research over the last decades has provided new insight into the structure and the function of milk bioactive peptides. Some of these peptides are delivered directly into milk, and some are encrypted in major proteins such as caseins and lactoglobulins. These peptides have antimicrobial functions modulating the gut microflora. Even when milk is undisputedly the first food for mammals, milk proteins sometimes can be a health threat, either because of allergic

Antimicrobial Cationic Peptides—Advances in Research and Application: 2012 Edition

Antimicrobial Cationic Peptides—Advances in Research and Application: 2012 Edition
  • Author : Anonim
  • Publisher : ScholarlyEditions
  • Release : 26 December 2012
GET THIS BOOKAntimicrobial Cationic Peptides—Advances in Research and Application: 2012 Edition

Antimicrobial Cationic Peptides—Advances in Research and Application: 2012 Edition is a ScholarlyEditions™ eBook that delivers timely, authoritative, and comprehensive information about Antimicrobial Cationic Peptides. The editors have built Antimicrobial Cationic Peptides—Advances in Research and Application: 2012 Edition on the vast information databases of ScholarlyNews.™ You can expect the information about Antimicrobial Cationic Peptides in this eBook to be deeper than what you can access anywhere else, as well as consistently reliable, authoritative, informed, and relevant. The content of Antimicrobial Cationic

Nanostructures for Antimicrobial Therapy

Nanostructures for Antimicrobial Therapy
  • Author : Anton Ficai,Alexandru Mihai Grumezescu
  • Publisher : Elsevier
  • Release : 29 May 2017
GET THIS BOOKNanostructures for Antimicrobial Therapy

Nanostructures for Antimicrobial Therapy discusses the pros and cons of the use of nanostructured materials in the prevention and eradication of infections, highlighting the efficient microbicidal effect of nanoparticles against antibiotic-resistant pathogens and biofilms. Conventional antibiotics are becoming ineffective towards microorganisms due to their widespread and often inappropriate use. As a result, the development of antibiotic resistance in microorganisms is increasingly being reported. New approaches are needed to confront the rising issues related to infectious diseases. The merging of biomaterials,

Antimicrobial Resistance

Antimicrobial Resistance
  • Author : Yashwant Kumar
  • Publisher : BoD – Books on Demand
  • Release : 02 May 2019
GET THIS BOOKAntimicrobial Resistance

The discovery of antibiotics was considered a milestone in health sciences and became the mainstay of antimicrobial therapy to treat and control bacterial infections. However, its utility has subsequently become limited, due to the emergence and spread of antimicrobial resistance among different bacterial species, which has emerged as a global threat. The development and spread of antimicrobial resistance have been attributed to many factors, including indiscriminate use of antibiotics in the healthcare and livestock industries. The present scenario of antibiotic

New Weapons to Control Bacterial Growth

New Weapons to Control Bacterial Growth
  • Author : Tomas G. Villa,Miguel Vinas
  • Publisher : Springer
  • Release : 24 March 2016
GET THIS BOOKNew Weapons to Control Bacterial Growth

Written by specialists in the different fields, this book presents new perspectives and insights into strategies and weapons to fight microbial infections. It also reviews the “state of the art” of alternative treatment approaches and new therapeutic agents to deal with infections caused by multidrug-resistant microorganisms. In an era of accumulated resistance to current antibiotics, it is vital that this is undertaken without further delay. Aspects discussed include the control of RNA synthesis, the use of bacteriocins or enzybiotics (bacteriophages

Pathogenesis of Periodontal Diseases

Pathogenesis of Periodontal Diseases
  • Author : Nagihan Bostanci,Georgios N. Belibasakis
  • Publisher : Springer
  • Release : 25 September 2017
GET THIS BOOKPathogenesis of Periodontal Diseases

This book aims to provide clinicians with a refined understanding of the biology that underlies periodontal diseases, thereby offering a sound basis for improved clinical decision making with regard to prevention strategies, diagnosis, and therapy. All significant aspects of periodontal pathogenesis are covered, including the roles played by the oral microbiome and biofilms, bacterial virulence factors, cells of the immune system, matrix metalloproteinases, proinflammatory and osteolytic cytokines, genetic factors, and antimicrobial peptides. Periodontal diseases are among the most common infectious

Host Defense Peptides and Their Potential as Therapeutic Agents

Host Defense Peptides and Their Potential as Therapeutic Agents
  • Author : Richard M. Epand
  • Publisher : Springer
  • Release : 06 May 2016
GET THIS BOOKHost Defense Peptides and Their Potential as Therapeutic Agents

This book offers an overview of our current understanding of host defense peptides and their potential for clinical applications as well as some of the obstacles to this. The chapters, written by leading experts in the field, detail the number and diversity of host defense peptides, and discuss the therapeutic potential not only of antibacterial, but also of antifungal, antiviral, plant antimicrobial and anticancer host defense peptides. The authors provide new insights into their mechanisms of action and their immunomodulatory

Emerging Nanotechnologies in Immunology

Emerging Nanotechnologies in Immunology
  • Author : Ranjita Shegokar,Eliana B. Souto
  • Publisher : William Andrew
  • Release : 17 May 2018
GET THIS BOOKEmerging Nanotechnologies in Immunology

Emerging Nanotechnologies in Immunology: The Design, Applications and Toxicology of Nanopharmaceuticals and Nanovaccines aims to deliver a systematic and comprehensive review of data concerning the nature of interaction and nano-related risks between the nanopharmaceuticals currently in the pipeline of S&T development for skin, ocular and nasal drug delivery, including absorption, toxicity, and the ability to distribute after systemic exposure. The book's contributors address a representative set of the broad spectrum of nanopharmaceutics presently being used, including cationic lipid nanoparticles,

Prebiotics and Probiotics

Prebiotics and Probiotics
  • Author : Anonim
  • Publisher : BoD – Books on Demand
  • Release : 04 March 2020
GET THIS BOOKPrebiotics and Probiotics

Probiotic bacteria are found in the intestinal microbiota of the host and favor multiple metabolic reactions. Prebiotics provide food for probiotic bacteria and have an effect on their own performance in favor of host health. Numerous metabolic and immunological mechanisms are involved in its effects. Probiotics have been studied for several decades and their use for human consumption is still unclear. However, new types of molecules with prebiotic functions and components of probiotic bacteria with therapeutic potential are still being

Glucocorticoids

Glucocorticoids
  • Author : Xiaoxiao Qian
  • Publisher : BoD – Books on Demand
  • Release : 28 November 2012
GET THIS BOOKGlucocorticoids

As one class of the most important steroid hormones, glucocorticoids have long been recognised and their therapeutic benefits have been widely used in clinical treatment, especially in anti-inflammation cases. Glucocorticoids regulate various processes in the body including the mobilization of energy stores, immune functions, gene expression, and maintenance of the homeostasis as well as the stress response, this is not surprising that the concept of "glucocorticoids" is mentioned in almost all medical text books that focus on specific organs or