Antimicrobial Peptides in Gastrointestinal Diseases

Antimicrobial peptides (AMPs), including cathelicidins and defensins are host defence peptides that carry out multiple roles in the gastrointestinal (GI) tract. Antimicrobial Peptides in Gastrointestinal Diseases presents knowledge about the physiological functions and pharmacological actions of AMPs in inflammation, cancer, and further infection of the GI tract. The book provides coverage from the basic research to clinical application for GI diseases. Current research and development of AMPs is presented, opening the way for further work on these peptides, not only in the context of GI diseases, but also for similar pathologies in other organs. AMPs are key to the regulation of human microbiome and second line defence in the GI mucosa, prevent colonization of pathogens and modulation of innate response to invading pathogens, and modify immunological reactions during inflammatory processes and oncogenic development in the GI mucosa. More importantly, AMPs possess diversified anti-microbial actions against various infectious diseases in the GI tract. With these physiological functions and pharmacological actions, AMPs have significant potential as therapeutic agents for the treatment of inflammation, cancer and further infection in the GI tract. Provides an overview of AMPs, particularly cathelicidin and defensin, in different diseases Covers inflammation and ulcer repair in the stomach and colon and carcinogenesis in the GI tract Presents AMP information and knowledge in a concise manner Gives useful information on all aspects of AMPs Promotes research on AMPs and their development as drugs, from bench, to clinical application

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  • Author : Chi Hin Cho
  • Publisher : Academic Press
  • Pages : 186 pages
  • ISBN : 0128143207
  • Rating : 4/5 from 21 reviews
CLICK HERE TO GET THIS BOOKAntimicrobial Peptides in Gastrointestinal Diseases

Antimicrobial Peptides in Gastrointestinal Diseases

Antimicrobial Peptides in Gastrointestinal Diseases
  • Author : Chi Hin Cho
  • Publisher : Academic Press
  • Release : 06 June 2018
GET THIS BOOKAntimicrobial Peptides in Gastrointestinal Diseases

Antimicrobial peptides (AMPs), including cathelicidins and defensins are host defence peptides that carry out multiple roles in the gastrointestinal (GI) tract. Antimicrobial Peptides in Gastrointestinal Diseases presents knowledge about the physiological functions and pharmacological actions of AMPs in inflammation, cancer, and further infection of the GI tract. The book provides coverage from the basic research to clinical application for GI diseases. Current research and development of AMPs is presented, opening the way for further work on these peptides, not only

Antimicrobial Peptides

Antimicrobial Peptides
  • Author : Jürgen Harder,Jens-M. Schröder
  • Publisher : Springer
  • Release : 24 December 2015
GET THIS BOOKAntimicrobial Peptides

This book focuses on the importance of human antimicrobial peptides (AMP) in keeping the host healthy and preventing infectious diseases. The first chapters deal with several examples of the role of AMP in different epithelial organs (skin and wound healing, eye, lung, genito-urinary tract, gut), which are exposed to different kinds of infectious microorganisms and as a result produce different patterns of AMP. Examples of the dysregulation of AMP expression and function promoting infections are discussed. The capacity of AMP

Antimicrobial Peptides

Antimicrobial Peptides
  • Author : Jürgen Harder,Jens-M. Schröder
  • Publisher : Springer
  • Release : 24 December 2015
GET THIS BOOKAntimicrobial Peptides

This book focuses on the importance of human antimicrobial peptides (AMP) in keeping the host healthy and preventing infectious diseases. The first chapters deal with several examples of the role of AMP in different epithelial organs (skin and wound healing, eye, lung, genito-urinary tract, gut), which are exposed to different kinds of infectious microorganisms and as a result produce different patterns of AMP. Examples of the dysregulation of AMP expression and function promoting infections are discussed. The capacity of AMP

Antimicrobial Peptides and Innate Immunity

Antimicrobial Peptides and Innate Immunity
  • Author : Pieter S. Hiemstra,Sebastian A. J. Zaat
  • Publisher : Springer Science & Business Media
  • Release : 01 February 2013
GET THIS BOOKAntimicrobial Peptides and Innate Immunity

Antimicrobial peptides have been the subject of intense research in the past decades, and are now considered as an essential part of the defense system in bacteria, plants, animals and humans. his book provides an update on these effector molecules of the innate immune system both for researchers who are already actively involved in the area, and for those with a general interest in the topic. The book starts with an overview of the evolution of cysteine-containing antimicrobial peptides (including

Crohn's Disease and Ulcerative Colitis

Crohn's Disease and Ulcerative Colitis
  • Author : Daniel C. Baumgart
  • Publisher : Springer
  • Release : 01 March 2017
GET THIS BOOKCrohn's Disease and Ulcerative Colitis

This new edition is a unique combined resource for physicians and scientists addressing the needs of both groups. In addition to stimulating exchange and collaboration and shortening the path between discovery and application of new knowledge, the book helps clinicians understand new therapeutic concepts from their origins. The volume serves as a comprehensive guide to the current diagnostic modalities, including enhanced imaging techniques such as MRI and CT enterography, virtual colonoscopy, ultrasound, and endomicroscopy, as well as conventional and complex

Nutraceutical Proteins and Peptides in Health and Disease

Nutraceutical Proteins and Peptides in Health and Disease
  • Author : Yoshinori Mine,Fereidoon Shahidi
  • Publisher : CRC Press
  • Release : 29 September 2005
GET THIS BOOKNutraceutical Proteins and Peptides in Health and Disease

Reports of the beneficial health effects of some peptides have begun to make their way into the scientific literature. Peptides can act as immunomodulators, and have been shown to have a positive influence on calcium absorption, and on regulation of serum cholesterol. A number of peptides may also possess antimicrobial properties that enhance the body's defense mechanisms, and others may produce inhibitory effects for angiotensin-I-converting enzyme (ACE), leading to novel treatments for blood pressure conditions, heart failure, and diabetes. Modern

Dietary Interventions in Gastrointestinal Diseases

Dietary Interventions in Gastrointestinal Diseases
  • Author : Ronald Ross Watson,Victor R. Preedy
  • Publisher : Academic Press
  • Release : 10 January 2019
GET THIS BOOKDietary Interventions in Gastrointestinal Diseases

Dietary Interventions in Gastrointestinal Diseases: Foods, Nutrients and Dietary Supplements provides valuable insights into the agents that affect metabolism and other health-related conditions in the gastrointestinal system. It provides nutritional treatment options for those suffering from gastrointestinal diseases including Crohn’s Disease, Inflammatory Bowel Disease, Ulcerative Colitis and Allergies, among others. Information is presented on a variety of foods, including herbs, fruits, soy and olive oil, thus showing that changes in intake can change antioxidant and disease preventing non-nutrients and

Peptide Drug Discovery and Development

Peptide Drug Discovery and Development
  • Author : Miguel Castanho,Nuno Santos
  • Publisher : John Wiley & Sons
  • Release : 24 October 2011
GET THIS BOOKPeptide Drug Discovery and Development

Filling a real knowledge gap, this handbook and ready reference is both modern and forward-looking in its emphasis on the "bench to bedside" translational approach to drug development. Clearly structured into three major parts, the book stakes out the boundaries of peptide drug development in the preclinical as well as clinical stages. The first part provides a general background and focuses on the characteristic strengths and weaknesses of peptide drugs. The second section contains five cases studies of peptides from

Handbook of Biologically Active Peptides

Handbook of Biologically Active Peptides
  • Author : Abba Kastin
  • Publisher : Academic Press
  • Release : 26 January 2013
GET THIS BOOKHandbook of Biologically Active Peptides

Handbook of Biologically Active Peptides, Second Edition, is the definitive, indispensable reference for peptide researchers, biochemists, cell and molecular biologists, neuroscientists, pharmacologists, and endocrinologists. Its chapters are designed to be a source for workers in the field and enable researchers working in a specific area to examine related areas outside their expertise. Peptides play a crucial role in many physiological processes, including actions as neurotransmitters, hormones, and antibiotics. Research has shown their importance in such fields as neuroscience, immunology, pharmacology,

Milk Proteins

Milk Proteins
  • Author : Isabel Gigli
  • Publisher : BoD – Books on Demand
  • Release : 07 September 2016
GET THIS BOOKMilk Proteins

Milk proteins have nutritional value and extraordinary biological properties. Research over the last decades has provided new insight into the structure and the function of milk bioactive peptides. Some of these peptides are delivered directly into milk, and some are encrypted in major proteins such as caseins and lactoglobulins. These peptides have antimicrobial functions modulating the gut microflora. Even when milk is undisputedly the first food for mammals, milk proteins sometimes can be a health threat, either because of allergic

Sleisenger and Fordtran's Gastrointestinal and Liver Disease E-Book

Sleisenger and Fordtran's Gastrointestinal and Liver Disease E-Book
  • Author : Mark Feldman,Lawrence S. Friedman,Lawrence J. Brandt
  • Publisher : Elsevier Health Sciences
  • Release : 03 May 2010
GET THIS BOOKSleisenger and Fordtran's Gastrointestinal and Liver Disease E-Book

Make optimal use of the newest techniques, technologies, and treatments with Sleisenger and Fordtran's Gastrointestinal and Liver Disease - the indispensable information source in this broad field! Edited by Mark Feldman, MD, Lawrence S. Friedman, MD, and Lawrence J. Brandt, MD, this 9th Edition equips you with the amassed knowledge of hundreds of respected authorities from around the world, helping you to overcome all of your most complex clinical challenges and make the most effective use of the newest techniques,

Antimicrobial Peptides

Antimicrobial Peptides
  • Author : David A. Phoenix,Sarah R. Dennison,Frederick Harris
  • Publisher : John Wiley & Sons
  • Release : 27 December 2012
GET THIS BOOKAntimicrobial Peptides

In this text, the small team of expert authors presents the field in a comprehensive and accessible manner that is well suited for students and junior researchers. The result is a highly readable and systematically structured introduction to antimicrobial peptides, their structure, biological function and mode of action. The authors point the way towards a rational design of this potentially highly effective new class of clinical antibiotics on the brink of industrial application. They do this by discussing their design

Infectious Diseases of the Fetus and Newborn E-Book

Infectious Diseases of the Fetus and Newborn E-Book
  • Author : Jack S. Remington,Christopher B. Wilson,Victor Nizet,Jerome O. Klein,Yvonne Maldonado
  • Publisher : Elsevier Health Sciences
  • Release : 27 August 2010
GET THIS BOOKInfectious Diseases of the Fetus and Newborn E-Book

Infectious Diseases of the Fetus and Newborn Infant, written and edited by Drs. Remington, Klein, Wilson, Nizet, and Maldonado, remains the definitive source of information in this field. The 7th edition of this authoritative reference provides the most up-to-date and complete guidance on infections found in utero, during delivery, and in the neonatal period in both premature and term infants. Special attention is given to the prevention and treatment of these diseases found in developing countries as well as the

New Weapons to Control Bacterial Growth

New Weapons to Control Bacterial Growth
  • Author : Tomas G. Villa,Miguel Vinas
  • Publisher : Springer
  • Release : 24 March 2016
GET THIS BOOKNew Weapons to Control Bacterial Growth

Written by specialists in the different fields, this book presents new perspectives and insights into strategies and weapons to fight microbial infections. It also reviews the “state of the art” of alternative treatment approaches and new therapeutic agents to deal with infections caused by multidrug-resistant microorganisms. In an era of accumulated resistance to current antibiotics, it is vital that this is undertaken without further delay. Aspects discussed include the control of RNA synthesis, the use of bacteriocins or enzybiotics (bacteriophages