Approaches to the Purification Analysis and Characterization of Antibody Based Therapeutics

Approaches to the Purification, Analysis and Characterization of Antibody-Based Therapeutics provides the interested and informed reader with an overview of current approaches, strategies and considerations relating to the purification, analytics and characterization of therapeutic antibodies and related molecules. While there are obviously other books published in and around this subject area, they seem to be either older (c.a. year 2000 publication date) or are more limited in scope. The book will include an extensive bibliography of the published literature in the respective areas covered. It is not, however, intended to be a how-to methods book. Covers the vital new area of R&D on therapeutic antibodies Written by leading scientists and researchers Up-to-date coverage and includes a detailed bibliography

Produk Detail:

  • Author : Allan Matte
  • Publisher : Elsevier
  • Pages : 222 pages
  • ISBN : 0081030193
  • Rating : 4/5 from 21 reviews
CLICK HERE TO GET THIS BOOKApproaches to the Purification Analysis and Characterization of Antibody Based Therapeutics

Approaches to the Purification, Analysis and Characterization of Antibody-Based Therapeutics

Approaches to the Purification, Analysis and Characterization of Antibody-Based Therapeutics
  • Author : Allan Matte
  • Publisher : Elsevier
  • Release : 07 September 2020
GET THIS BOOKApproaches to the Purification, Analysis and Characterization of Antibody-Based Therapeutics

Approaches to the Purification, Analysis and Characterization of Antibody-Based Therapeutics provides the interested and informed reader with an overview of current approaches, strategies and considerations relating to the purification, analytics and characterization of therapeutic antibodies and related molecules. While there are obviously other books published in and around this subject area, they seem to be either older (c.a. year 2000 publication date) or are more limited in scope. The book will include an extensive bibliography of the published literature in

Protein and Peptide Mass Spectrometry in Drug Discovery

Protein and Peptide Mass Spectrometry in Drug Discovery
  • Author : Michael L. Gross,Guodong Chen,Birendra Pramanik
  • Publisher : John Wiley & Sons
  • Release : 26 September 2011
GET THIS BOOKProtein and Peptide Mass Spectrometry in Drug Discovery

The book that highlights mass spectrometry and its application in characterizing proteins and peptides in drug discovery An instrumental analytical method for quantifying the mass and characterization of various samples from small molecules to large proteins, mass spectrometry (MS) has become one of the most widely used techniques for studying proteins and peptides over the last decade. Bringing together the work of experts in academia and industry, Protein and Peptide Mass Spectrometry in Drug Discovery highlights current analytical approaches, industry

Development of Antibody-Based Therapeutics

Development of Antibody-Based Therapeutics
  • Author : Mohammad A. Tabrizi,Gadi G. Bornstein,Scott L. Klakamp
  • Publisher : Springer Science & Business Media
  • Release : 24 April 2012
GET THIS BOOKDevelopment of Antibody-Based Therapeutics

Translational strategies for development of antibody-based therapeutics should allow understanding of the relationship between the ‘unit dose’ and ‘unit effect’ with respect to both beneficial and deleterious effects from early stages of development. The flow of information from later to earlier stages of development should provide opportunities to facilitate selection of more effective novel and next-generation drug candidates. Selection and evaluation of relevant biomarkers in early preclinical development in "relevant" animal models should allow for identifying potential risks to humans

Process Scale Purification of Antibodies

Process Scale Purification of Antibodies
  • Author : Uwe Gottschalk
  • Publisher : John Wiley & Sons
  • Release : 03 April 2017
GET THIS BOOKProcess Scale Purification of Antibodies

Promoting a continued and much-needed renaissance in biopharmaceutical manufacturing, this book covers the different strategies and assembles top-tier technology experts to address the challenges of antibody purification. • Updates existing topics and adds new ones that include purification of antibodies produced in novel production systems, novel separation technologies, novel antibody formats and alternative scaffolds, and strategies for ton-scale manufacturing • Presents new and updated discussions of different purification technologies, focusing on how they can address the capacity crunch in antibody purification • Emphasizes

Cancer Immunology: Innovative Approaches to Therapy

Cancer Immunology: Innovative Approaches to Therapy
  • Author : Ronald B. Herberman
  • Publisher : Springer Science & Business Media
  • Release : 06 December 2012
GET THIS BOOKCancer Immunology: Innovative Approaches to Therapy

This volume is the second in the 'Cancer Treatment and Research' series focussing on basic and clinical tumor immunology. It has a rather different focus or emphasis from that of the first volume, published two years ago. That work (Basic and Clinical Tumor Immunology, R.B. Herberman, ed., Martinus Nijhoff Publishers, 1983) devoted considerable attention to up dated summaries in various areas of classical tumor immunology: specific antitumor immunity, the immunologic competence of cancer patietns, char acterization of human tumor-associated antigens,

Therapeutic Monoclonal Antibodies

Therapeutic Monoclonal Antibodies
  • Author : Zhiqiang An
  • Publisher : John Wiley & Sons
  • Release : 20 September 2011
GET THIS BOOKTherapeutic Monoclonal Antibodies

70-chapter authoritative reference that covers therapeutic monoclonal antibody discovery, development, and clinical applications while incorporating principles, experimental data, and methodologies. First book to address the discovery and development of antibody therapeutics in their entirety. Most chapters contain experimental data to illustrate the principles described in them. Authors provide detailed methodologies that readers can take away with them and use in their own laboratories.

Developability of Biotherapeutics

Developability of Biotherapeutics
  • Author : Sandeep Kumar,Satish Kumar Singh
  • Publisher : CRC Press
  • Release : 18 November 2015
GET THIS BOOKDevelopability of Biotherapeutics

Biopharmaceuticals are emerging as frontline medicines to combat several life-threatening and chronic diseases. However, such medicines are expensive to develop and produce on a commercial scale, contributing to rising healthcare costs. Developability of Biotherapeutics: Computational Approaches describes applications of computational and molecular modeling techniques that improve the overall process of discovery and development by removing empiricism. The concept of developability involves making rational choices at the pre-clinical stages of biopharmaceutical drug development that could positively impact clinical outcomes. The book

HPLC of Peptides and Proteins

HPLC of Peptides and Proteins
  • Author : Marie-Isabel Aguilar
  • Publisher : Springer Science & Business Media
  • Release : 25 January 2021
GET THIS BOOKHPLC of Peptides and Proteins

Hands-on experts from academia and industry comprehensively describe how to successfully perform all the critical HPLC techniques needed for the analysis of peptides and proteins. The methods range from commonly used techniques to those for capillary to large-scale preparative isolation. The authors have also presented a number of specific applications as case studies to illustrate the analytical approaches to a particular separation or assay challenge, with examples drawn from contemporary fields in biochemistry and biotechnology. Follow step-by-step instructions that ensure

Monoclonal Antibodies

Monoclonal Antibodies
  • Author : Philip Shepherd,Christopher J. Dean
  • Publisher : Practical Approach (Paperback)
  • Release : 25 January 2021
GET THIS BOOKMonoclonal Antibodies

Monoclonal Antibodies: A Practical Approach covers the preparation, testing, derivation, and applications of monoclonal antibodies. New immunological techniques incorporating tried and tested methodologies are described, making the book of interest to established and inexperienced immunologists. Both the standard somatic hybridization technique and recombinant techniques, including the use of phage libraries, for the preparation of rodent and human monoclonal antibodies are described. Protocols for both the small and large scale production are detailed, as well as purification and labelling (with both

Development of Antibody-Based Therapeutics

Development of Antibody-Based Therapeutics
  • Author : Mohammad A. Tabrizi,Gadi G. Bornstein,Scott L. Klakamp
  • Publisher : Springer
  • Release : 11 September 2018
GET THIS BOOKDevelopment of Antibody-Based Therapeutics

With a key focus on recent developments and advances in the field, this book provides in-depth coverage of topics fundamental to the development of targeted therapeutics. The expansion of targeted modalities in rapidly evolving therapeutic areas, such as immune-oncology, and developments with respect to combination therapies, novel technologies, and the therapeutic application of antibody-drug conjugates, are presented. Additionally, the book builds upon topics discussed in the first edition (2012) where recent innovations warrant elaboration. This, the second edition of Development of