Artemisinin Based and Other Antimalarials

Artemisinin-Based and Other Antimalarials: Detailed Account of Studies by Chinese Scientists Who Discovered and Developed Them provides a historical and scientific background of the discovery and development of artemisinin, artemisinin derivatives, combination drugs and related chemicals. It is a historical document, a scientific treatise, and a fascinating description of innovative research on new drug development that is carried out under extremely difficult conditions. The book also includes detailed experiments, physical-chemical procedures, practical methodologies and clinical trials. It is a valuable reference for students and researchers in the fields of scientific history, medicine, pharmaceutical science, chemistry, pharmacology and toxicology. Presents details of all stages of drug development, including in vitro experiment, animal exploratory studies, animal tests for toxicity, safety and efficacy followed by stages I, II, III and IV, safety and efficacy in human volunteers and patients with malaria Provides many physical-chemical laboratory procedures, such as NMR, MS, HPLC and X-ray diffraction used in drug development Includes practical methodology of clinical trials from many research centers and countries to demonstrate the importance of this discovery

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  • Author : Guoqiao Li
  • Publisher : Academic Press
  • Pages : 736 pages
  • ISBN : 0128132116
  • Rating : 4/5 from 21 reviews
CLICK HERE TO GET THIS BOOKArtemisinin Based and Other Antimalarials

Artemisinin-Based and Other Antimalarials

Artemisinin-Based and Other Antimalarials
  • Author : Guoqiao Li,Ying Li,Zelin Li,Meiyi Zeng
  • Publisher : Academic Press
  • Release : 28 November 2017
GET THIS BOOKArtemisinin-Based and Other Antimalarials

Artemisinin-Based and Other Antimalarials: Detailed Account of Studies by Chinese Scientists Who Discovered and Developed Them provides a historical and scientific background of the discovery and development of artemisinin, artemisinin derivatives, combination drugs and related chemicals. It is a historical document, a scientific treatise, and a fascinating description of innovative research on new drug development that is carried out under extremely difficult conditions. The book also includes detailed experiments, physical-chemical procedures, practical methodologies and clinical trials. It is a valuable

Saving Lives, Buying Time

Saving Lives, Buying Time
  • Author : Institute of Medicine,Board on Global Health,Committee on the Economics of Antimalarial Drugs
  • Publisher : National Academies Press
  • Release : 09 October 2004
GET THIS BOOKSaving Lives, Buying Time

For more than 50 years, low-cost antimalarial drugs silently saved millions of lives and cured billions of debilitating infections. Today, however, these drugs no longer work against the deadliest form of malaria that exists throughout the world. Malaria deaths in sub-Saharan Africaâ€"currently just over one million per yearâ€"are rising because of increased resistance to the old, inexpensive drugs. Although effective new drugs called “artemisinins†are available, they are unaffordable for the majority of the affected population, even at a

Guidelines for the Treatment of Malaria

Guidelines for the Treatment of Malaria
  • Author : World Health Organization
  • Publisher : World Health Organization
  • Release : 25 January 2021
GET THIS BOOKGuidelines for the Treatment of Malaria

"The purpose of this document is to provide comprehensible, global, evidence-based guidelines to help formulate policies and protocols for the treatment of malaria. Information is presented on the treatment of uncomplicated malaria, including disease in special groups (young children, pregnant women, people who are HIV positive, travellers from non-malaria endemic regions) and in complex emergency situations and severe malaria."--Publisher's description.

Treatment and Prevention of Malaria

Treatment and Prevention of Malaria
  • Author : Henry M. Staines,Sanjeev Krishna
  • Publisher : Springer Science & Business Media
  • Release : 06 January 2012
GET THIS BOOKTreatment and Prevention of Malaria

Malaria has defeated previous efforts at eradication and remains a massive global public health problem despite being readily preventable and treatable. It is a devastating disease that also extracts huge economic costs from the poorest countries in endemic regions. Starting with an overview of the disease and its current political, financial and technical context, this Milestones in Drug Therapy volume describes the history, chemistry, mechanisms of action and resistance, preclinical and clinical use, pharmacokinetics and safety and tolerability of the

Towards Malaria Elimination

Towards Malaria Elimination
  • Author : Sylvie Manguin,Vas Dev
  • Publisher : BoD – Books on Demand
  • Release : 18 July 2018
GET THIS BOOKTowards Malaria Elimination

Towards Malaria Elimination - A Leap Forward was started to mark the occasion for renewed commitment to end malaria transmission for good (the WHO's call for "Malaria Free World" by 2030). This book is dedicated for the benefit of researchers, scientists, program and policy managers, students and anyone interested in malaria and other mosquito-borne diseases with the goal of sharing recent information on success stories, innovative control approaches and challenges in different regions of the world. Some main issues that emerged

A Detailed Chronological Record of Project 523 and the Discovery and Development of Qinghaosu (Artemisinin)

A Detailed Chronological Record of Project 523 and the Discovery and Development of Qinghaosu (Artemisinin)
  • Author : Zhang Jianfang
  • Publisher : Strategic Book Publishing
  • Release : 01 February 2013
GET THIS BOOKA Detailed Chronological Record of Project 523 and the Discovery and Development of Qinghaosu (Artemisinin)

This is an account of a project in China carried out in secrecy from the Chinese people and the Western World during the tumultuous years of the Cultural Revolution. Project 523, as it was called, resulted in one of the most significant advances in the treatment of malaria since the discovery and first use of quinine over 300 years ago. The origin of the project was a request from the North Vietnamese Government to Mao Zedong in China, for assistance in managing

Guidelines for the Treatment of Malaria. Third Edition

Guidelines for the Treatment of Malaria. Third Edition
  • Author : World Health Organization
  • Publisher : World Health Organization
  • Release : 13 August 2015
GET THIS BOOKGuidelines for the Treatment of Malaria. Third Edition

Malaria remains an important cause of illness and death in children and adults in countries in which it is endemic. Malaria control requires an integrated approach including prevention (primarily vector control) and prompt treatment with effective antimalarial agents. Malaria case management consisting of prompt diagnosis and effective treatment remains a vital component of malaria control and elimination strategies. Since the publication of the first edition of the Guidelines for the treatment of malaria in 2006 and the second edition in 2010 all

Pharmacokinetics and Pharmacodynamics of Antimalarial Drugs Used in Combination Therapy

Pharmacokinetics and Pharmacodynamics of Antimalarial Drugs Used in Combination Therapy
  • Author : Qigui Li,Mark R. Hickman
  • Publisher : Bentham Science Publishers
  • Release : 04 June 2015
GET THIS BOOKPharmacokinetics and Pharmacodynamics of Antimalarial Drugs Used in Combination Therapy

Malaria takes a great toll on human health and well-being, particularly in tropical regions including Sub-Saharan Africa, Southeast Asia, Oceania and parts of the Americas. In recent years, some Plasmodium strains have become increasingly resistant to all classes of conventional antimalarial drugs currently in use. Researchers have, therefore, stepped up efforts to revise atimalarial drug policies, develop new drugs, and implement new strategies to combat this disease. In order to prevent widespread resistance, antimalarial combination therapies (ACTs) have been deployed

Malaria: Drugs, Disease and Post-genomic Biology

Malaria: Drugs, Disease and Post-genomic Biology
  • Author : David Sullivan,Sanjeev Krishna
  • Publisher : Springer Science & Business Media
  • Release : 14 January 2006
GET THIS BOOKMalaria: Drugs, Disease and Post-genomic Biology

Despite rapid increases in knowledge, malaria continues to kill more than a million people each year and causes symptomatic disease in a further 300 million individuals. This volume brings some of the world's best investigators to describe recent advances in both the scientific and clinical aspects of malaria, and bridges between the two.

Antimalarial Chemotherapy

Antimalarial Chemotherapy
  • Author : Philip J. Rosenthal
  • Publisher : Springer Science & Business Media
  • Release : 01 April 2001
GET THIS BOOKAntimalarial Chemotherapy

Philip Rosenthal, MD, and a panel of leading malaria experts drawn from academia, the military, and international health organizations survey the latest scientific understanding of antimalarial chemotherapy, emphasizing the molecular mechanisms of resistance and the description of important new targets. Their survey covers the current status of malarial and antimalarial chemotherapy, the relevant biology and biochemistry of malaria parasites, the antimalarial drugs currently available, new chemical approaches to chemotherapy, and possible new targets for chemotherapy. Comprehensive and cutting-edge, Antimalarial Chemotherapy:

An Overview of Tropical Diseases

An Overview of Tropical Diseases
  • Author : Amidou Samie
  • Publisher : BoD – Books on Demand
  • Release : 02 December 2015
GET THIS BOOKAn Overview of Tropical Diseases

Tropical diseases affect millions of people throughout the world and particularly in the developing countries. The millennium development goals had specifically targeted HIV/AIDS and Malaria for substantial reduction as well as Tuberculosis while many other tropical diseases have been neglected. The new sustainable development goals have not made such distinction and have targeted all diseases for elimination for the improvement of the quality of life of human beings on earth. The present book was developed to provide an update

Psychiatry in Communist Europe

Psychiatry in Communist Europe
  • Author : Sarah Marks,Mat Savelli
  • Publisher : Palgrave Macmillan
  • Release : 15 July 2015
GET THIS BOOKPsychiatry in Communist Europe

This is the first book to address the history of psychiatry under Communism in Central and Eastern Europe, from the Soviet Union to East Germany. It brings together new research addressing understandings of mental health and disorder, treatments and therapies, and the interplay between politics, ideology and psychiatry. It challenges assumptions about the extent of political control, exploring beyond the instances of punitive abuse of psychiatry, and recognizing the international exchanges which informed the development of research and practice in