Artemisinin Based and Other Antimalarials

Artemisinin-Based and Other Antimalarials: Detailed Account of Studies by Chinese Scientists Who Discovered and Developed Them provides a historical and scientific background of the discovery and development of artemisinin, artemisinin derivatives, combination drugs and related chemicals. It is a historical document, a scientific treatise, and a fascinating description of innovative research on new drug development that is carried out under extremely difficult conditions. The book also includes detailed experiments, physical-chemical procedures, practical methodologies and clinical trials. It is a valuable reference for students and researchers in the fields of scientific history, medicine, pharmaceutical science, chemistry, pharmacology and toxicology. Presents details of all stages of drug development, including in vitro experiment, animal exploratory studies, animal tests for toxicity, safety and efficacy followed by stages I, II, III and IV, safety and efficacy in human volunteers and patients with malaria Provides many physical-chemical laboratory procedures, such as NMR, MS, HPLC and X-ray diffraction used in drug development Includes practical methodology of clinical trials from many research centers and countries to demonstrate the importance of this discovery

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  • Author : Guoqiao Li
  • Publisher : Academic Press
  • Pages : 736 pages
  • ISBN : 0128132116
  • Rating : 4/5 from 21 reviews
CLICK HERE TO GET THIS BOOKArtemisinin Based and Other Antimalarials

Artemisinin-Based and Other Antimalarials

Artemisinin-Based and Other Antimalarials
  • Author : Guoqiao Li,Ying Li,Zelin Li,Meiyi Zeng
  • Publisher : Academic Press
  • Release : 28 November 2017
GET THIS BOOKArtemisinin-Based and Other Antimalarials

Artemisinin-Based and Other Antimalarials: Detailed Account of Studies by Chinese Scientists Who Discovered and Developed Them provides a historical and scientific background of the discovery and development of artemisinin, artemisinin derivatives, combination drugs and related chemicals. It is a historical document, a scientific treatise, and a fascinating description of innovative research on new drug development that is carried out under extremely difficult conditions. The book also includes detailed experiments, physical-chemical procedures, practical methodologies and clinical trials. It is a valuable

Saving Lives, Buying Time

Saving Lives, Buying Time
  • Author : Institute of Medicine,Board on Global Health,Committee on the Economics of Antimalarial Drugs
  • Publisher : National Academies Press
  • Release : 09 September 2004
GET THIS BOOKSaving Lives, Buying Time

For more than 50 years, low-cost antimalarial drugs silently saved millions of lives and cured billions of debilitating infections. Today, however, these drugs no longer work against the deadliest form of malaria that exists throughout the world. Malaria deaths in sub-Saharan Africaâ€"currently just over one million per yearâ€"are rising because of increased resistance to the old, inexpensive drugs. Although effective new drugs called “artemisinins†are available, they are unaffordable for the majority of the affected population, even at a

Examining USAID's Anti-malaria Policies

Examining USAID's Anti-malaria Policies
  • Author : Heather Adamson,United States. Congress. Senate. Committee on Homeland Security and Governmental Affairs. Subcommittee on Federal Financial Management, Government Information, and International Security
  • Publisher : Amicus
  • Release : 13 April 2021
GET THIS BOOKExamining USAID's Anti-malaria Policies

Amicus Readers at level 1 include: a picture glossary, a table of contents, index, websites, and literacy notes located in the back of each book. Additionally, content words are introduced within the text supported by a variety of photo labels. In particular, this title describes a shopping trip to the grocery store, including various departments such as the bakery and deli. Includes visual literacy activity.

Antimalarial Chemotherapy

Antimalarial Chemotherapy
  • Author : Philip J. Rosenthal
  • Publisher : Springer Science & Business Media
  • Release : 01 April 2001
GET THIS BOOKAntimalarial Chemotherapy

Philip Rosenthal, MD, and a panel of leading malaria experts drawn from academia, the military, and international health organizations survey the latest scientific understanding of antimalarial chemotherapy, emphasizing the molecular mechanisms of resistance and the description of important new targets. Their survey covers the current status of malarial and antimalarial chemotherapy, the relevant biology and biochemistry of malaria parasites, the antimalarial drugs currently available, new chemical approaches to chemotherapy, and possible new targets for chemotherapy. Comprehensive and cutting-edge, Antimalarial Chemotherapy:

Guidelines for the Treatment of Malaria

Guidelines for the Treatment of Malaria
  • Author : World Health Organization
  • Publisher : World Health Organization
  • Release : 13 April 2021
GET THIS BOOKGuidelines for the Treatment of Malaria

"The purpose of this document is to provide comprehensible, global, evidence-based guidelines to help formulate policies and protocols for the treatment of malaria. Information is presented on the treatment of uncomplicated malaria, including disease in special groups (young children, pregnant women, people who are HIV positive, travellers from non-malaria endemic regions) and in complex emergency situations and severe malaria."--Publisher's description.

Antimalarial Agents

Antimalarial Agents
  • Author : Graham L. Patrick
  • Publisher : Elsevier
  • Release : 16 June 2020
GET THIS BOOKAntimalarial Agents

Antimalarial Agents: Design and Mechanism of Action seeks to support medicinal chemists in their work toward antimalarial solutions, providing practical guidance on past and current developments and highlighting promising leads for the future. Malaria is a deadly disease which threatens half of the world's population. Advances over several decades have seen vast improvements in the eff ectiveness of both preventative measures and treatments, but the rapid adaptability of the disease means that the ongoing search for improved and novel antimalarial

Treatment and Prevention of Malaria

Treatment and Prevention of Malaria
  • Author : Henry M. Staines,Sanjeev Krishna
  • Publisher : Springer Science & Business Media
  • Release : 06 January 2012
GET THIS BOOKTreatment and Prevention of Malaria

Malaria has defeated previous efforts at eradication and remains a massive global public health problem despite being readily preventable and treatable. It is a devastating disease that also extracts huge economic costs from the poorest countries in endemic regions. Starting with an overview of the disease and its current political, financial and technical context, this Milestones in Drug Therapy volume describes the history, chemistry, mechanisms of action and resistance, preclinical and clinical use, pharmacokinetics and safety and tolerability of the

An Overview of Tropical Diseases

An Overview of Tropical Diseases
  • Author : Amidou Samie
  • Publisher : BoD – Books on Demand
  • Release : 02 December 2015
GET THIS BOOKAn Overview of Tropical Diseases

Tropical diseases affect millions of people throughout the world and particularly in the developing countries. The millennium development goals had specifically targeted HIV/AIDS and Malaria for substantial reduction as well as Tuberculosis while many other tropical diseases have been neglected. The new sustainable development goals have not made such distinction and have targeted all diseases for elimination for the improvement of the quality of life of human beings on earth. The present book was developed to provide an update

Towards Malaria Elimination

Towards Malaria Elimination
  • Author : Sylvie Manguin,Vas Dev
  • Publisher : BoD – Books on Demand
  • Release : 18 July 2018
GET THIS BOOKTowards Malaria Elimination

Towards Malaria Elimination - A Leap Forward was started to mark the occasion for renewed commitment to end malaria transmission for good (the WHO's call for "Malaria Free World" by 2030). This book is dedicated for the benefit of researchers, scientists, program and policy managers, students and anyone interested in malaria and other mosquito-borne diseases with the goal of sharing recent information on success stories, innovative control approaches and challenges in different regions of the world. Some main issues that emerged

Approaches to Design and Synthesis of Antiparasitic Drugs

Approaches to Design and Synthesis of Antiparasitic Drugs
  • Author : N. Anand,S. Sharma†
  • Publisher : Elsevier
  • Release : 10 July 1997
GET THIS BOOKApproaches to Design and Synthesis of Antiparasitic Drugs

This book presents a comprehensive and up to date account of the chemotherapy of parasitic diseases, both human and veterinary. The book starts with an overview of parasitic diseases. The body of the book is divided into two parts: antihelminthic drugs, and antiprotozoal drugs. Both parts start with chapters highlighting the 'biochemical targets' available for chemotherapeutic interference. Individual chapters deal with one chemical class of compounds and describe their origin, structure-activity relationship, mode of action, and methods of synthesis and

Assessment of Long-Term Health Effects of Antimalarial Drugs When Used for Prophylaxis

Assessment of Long-Term Health Effects of Antimalarial Drugs When Used for Prophylaxis
  • Author : National Academies of Sciences, Engineering, and Medicine,Health and Medicine Division,Board on Population Health and Public Health Practice
  • Publisher : National Academies Press
  • Release : 24 April 2020
GET THIS BOOKAssessment of Long-Term Health Effects of Antimalarial Drugs When Used for Prophylaxis

Among the many who serve in the United States Armed Forces and who are deployed to distant locations around the world, myriad health threats are encountered. In addition to those associated with the disruption of their home life and potential for combat, they may face distinctive disease threats that are specific to the locations to which they are deployed. U.S. forces have been deployed many times over the years to areas in which malaria is endemic, including in parts

Artemisia annua - Pharmacology and Biotechnology

Artemisia annua - Pharmacology and Biotechnology
  • Author : Tariq Aftab,Jorge F.S. Ferreira,M. Masroor A. Khan,M. Naeem
  • Publisher : Springer Science & Business Media
  • Release : 26 November 2013
GET THIS BOOKArtemisia annua - Pharmacology and Biotechnology

Artemisinin, a sesquiterpene lactone originally extracted from the medicinal plant Artemisia annua L., is an effective antimalarial agent, particularly for multi-drug resistant and cerebral malaria. However, the concentration of artemisinin in the plant is very low. Because the chemical synthesis of artemisinin is complicated and not economically feasible in view of the poor yield of the drug, the intact plant remains the only viable source of artemisinin production. Therefore, it is necessary to increase the concentration of artemisinin in A.

CDC Yellow Book 2018: Health Information for International Travel

CDC Yellow Book 2018: Health Information for International Travel
  • Author : Centers for Disease Control and Prevention CDC
  • Publisher : Oxford University Press
  • Release : 17 April 2017
GET THIS BOOKCDC Yellow Book 2018: Health Information for International Travel

THE ESSENTIAL WORK IN TRAVEL MEDICINE -- NOW COMPLETELY UPDATED FOR 2018 As unprecedented numbers of travelers cross international borders each day, the need for up-to-date, practical information about the health challenges posed by travel has never been greater. For both international travelers and the health professionals who care for them, the CDC Yellow Book 2018: Health Information for International Travel is the definitive guide to staying safe and healthy anywhere in the world. The fully revised and updated 2018 edition codifies the