Atlas of Histology of the Juvenile Rat

Atlas of Histology of the Juvenile Rat should be of interest to toxicologic pathologists, toxicologists, and other biological scientists who are interested in the histomorphology of juvenile rats. For several decades the laboratory rat has been used extensively in nonclinical toxicology studies designed to detect potential human toxicity of drugs, agrochemicals, industrial chemicals, and environmental hazards. These studies traditionally have involved young adult rats that are 8-10 weeks of age as studies are started. It is becoming increasingly apparent that children and young animals may have different responses to drug/chemical exposures, therefore, regulatory agencies are emphasizing toxicology studies in juvenile animals. While the histologic features of organs from young adult and aged laboratory rats are well known, less is known about the histologic features of organs from juvenile rats. Final histologic maturity of many organs is achieved postnatally, thus immature histologic features must be distinguished from chemical- or drug-related effects. While this postnatal organ development is known to exist as a general concept, detailed information regarding postnatal histologic development is not readily available. The Atlas includes organs that are typically sampled in nonclinical toxicology studies and presents the histologic features at weekly intervals, starting at birth and extending through postnatal day 42. Written and edited by highly experienced, board-certified toxicologic pathologists Includes more than 700 high-resolution microscopic images from organs that are typically examined in safety assessment toxicology studies Detailed figure legends and chapter narratives present the salient features of each organ at each time interval Figures are available for further study via Elsevier’s Virtual Microscope, which allows viewing of microscopic images at higher magnification Valuable resource for toxicologic pathologists who are confronted with interpretation of lesions in juvenile rats in situations where age-matched concurrent controls are not available for comparison, e.g., with unscheduled decedents Figures are available for further study on ScienceDirect with Virtual Microscope, which allows viewing of microscopic images at higher magnification

Produk Detail:

  • Author : George A Parker
  • Publisher : Academic Press
  • Pages : 462 pages
  • ISBN : 0128026960
  • Rating : 5/5 from 1 reviews
CLICK HERE TO GET THIS BOOKAtlas of Histology of the Juvenile Rat

Atlas of Histology of the Juvenile Rat

Atlas of Histology of the Juvenile Rat
  • Author : George A Parker,Catherine A. Picut
  • Publisher : Academic Press
  • Release : 04 May 2016
GET THIS BOOKAtlas of Histology of the Juvenile Rat

Atlas of Histology of the Juvenile Rat should be of interest to toxicologic pathologists, toxicologists, and other biological scientists who are interested in the histomorphology of juvenile rats. For several decades the laboratory rat has been used extensively in nonclinical toxicology studies designed to detect potential human toxicity of drugs, agrochemicals, industrial chemicals, and environmental hazards. These studies traditionally have involved young adult rats that are 8-10 weeks of age as studies are started. It is becoming increasingly apparent that

Anatomy and Histology of the Laboratory Rat in Toxicology and Biomedical Research

Anatomy and Histology of the Laboratory Rat in Toxicology and Biomedical Research
  • Author : Robert L. Maynard,Noel Downes
  • Publisher : Academic Press
  • Release : 08 February 2019
GET THIS BOOKAnatomy and Histology of the Laboratory Rat in Toxicology and Biomedical Research

Anatomy and Histology of the Laboratory Rat in Toxicology and Biomedical Research presents the detailed systematic anatomy of the rat, with a focus on toxicological needs. Most large works dealing with the laboratory rat provide a chapter on anatomy, but fall far short of the detailed account in this book which also focuses on the needs of toxicologists and others who use the rat as a laboratory animal. The book includes detailed guides on dissection methods and the location of

The Laboratory Rat

The Laboratory Rat
  • Author : Mark A. Suckow,F. Claire Hankenson,Ronald P. Wilson,Patricia L. Foley
  • Publisher : Academic Press
  • Release : 10 November 2019
GET THIS BOOKThe Laboratory Rat

The third edition of The Laboratory Rat features updated information on a variety of topics, including rats as research models for basic and translational research in areas such as genomics, alcoholism, diabetes, metabolic syndrome, obesity, neuroscience, spinal cord injury, traumatic brain injury, regenerative medicine, and infectious disease. New information related to the husbandry and veterinary care of rats is provided including topics related to nutrition, reproduction, anesthesia and surgery, infectious and noninfectious disease, and the care of surgical and other

Boorman's Pathology of the Rat

Boorman's Pathology of the Rat
  • Author : Andrew W. Suttie,Joel R. Leininger,Alys E. Bradley
  • Publisher : Academic Press
  • Release : 18 December 2017
GET THIS BOOKBoorman's Pathology of the Rat

Boorman’s Pathology of the Rat: Reference and Atlas, Second Edition, continues its history as the most comprehensive pathology reference on rat strains for researchers across science and medicine using rat models in the laboratory. It offers readers an added emphasis on the Sprague-Dawley and Wistar rat strains that is consistent with current research across academia, government, and industry. In addition, the book provides standard diagnostic criteria, basic content on histology, histological changes that result from drug toxicity and neoplasm,

Toxicologic Pathology for Non-Pathologists

Toxicologic Pathology for Non-Pathologists
  • Author : Thomas J. Steinbach,Daniel J. Patrick,Mary Ellen Cosenza
  • Publisher : Springer Nature
  • Release : 31 October 2019
GET THIS BOOKToxicologic Pathology for Non-Pathologists

This extensive volume began as a short course primarily geared toward toxicologists who want to expand their understanding of toxicologic pathology in order to be better study directors while also proving to be of great interest to other drug development scientists and regulatory reviewers. The overall goal is to help non-pathologists understand, contextualize, and communicate the pathology data and interpretations from the study pathologist in a practical and usable format. Within the book, readers will find an overview of general

Haschek and Rousseaux's Handbook of Toxicologic Pathology

Haschek and Rousseaux's Handbook of Toxicologic Pathology
  • Author : Wanda M. Haschek,Colin G. Rousseaux,Matthew A. Wallig,Brad Bolon
  • Publisher : Academic Press
  • Release : 20 October 2021
GET THIS BOOKHaschek and Rousseaux's Handbook of Toxicologic Pathology

Haschek and Rousseaux's Handbook of Toxicologic Pathology: Volume 1: Principles and Practice of Toxicologic Pathology is a key reference on the integration of structure and functional changes in tissues associated with the response to pharmaceuticals, chemicals and biologics. Volume 1 of the Fourth Edition covers the practice of toxicologic pathology in three parts: Principles of Toxicologic Pathology, Methods in Toxicologic Pathology, and the Practice of Toxicologic Pathology. Completely revised with a number of new chapters, Volume 1 of the Handbook of Toxicologic Pathology

Comprehensive Toxicology

Comprehensive Toxicology
  • Author : Anonim
  • Publisher : Elsevier
  • Release : 01 December 2017
GET THIS BOOKComprehensive Toxicology

Comprehensive Toxicology, Third Edition, discusses chemical effects on biological systems, with a focus on understanding the mechanisms by which chemicals induce adverse health effects. Organized by organ system, this comprehensive reference work addresses the toxicological effects of chemicals on the immune system, the hematopoietic system, cardiovascular system, respiratory system, hepatic toxicology, renal toxicology, gastrointestinal toxicology, reproductive and endocrine toxicology, neuro and behavioral toxicology, developmental toxicology and carcinogenesis, also including critical sections that cover the general principles of toxicology, cellular and

Reproductive and Developmental Toxicology

Reproductive and Developmental Toxicology
  • Author : Ramesh C. Gupta
  • Publisher : Academic Press
  • Release : 31 March 2022
GET THIS BOOKReproductive and Developmental Toxicology

Reproductive and Developmental Toxicology, Third Edition is a comprehensive and authoritative resource, providing the latest literature on this complex subject by focusing on three core components - parent, placenta and fetus - and the continuous changes that occur in each. Enriched with relevant references describing every aspect of reproductive toxicology, this revised and updated resource addresses the totality of the subject, discussing a broad range of topics including nanoparticles and radiation, gases and solvents, smoking, alcohol and drugs of abuse,

Immunopathology in Toxicology and Drug Development

Immunopathology in Toxicology and Drug Development
  • Author : George A. Parker
  • Publisher : Springer
  • Release : 28 March 2017
GET THIS BOOKImmunopathology in Toxicology and Drug Development

This book provides a fundamental understanding of immunopathology and immunopathologic processes, with particular attention to nonclinical toxicology studies. Chapters provide an overview of general immunobiology, cells of the immune system, signaling and effector molecules, and immunopathology assays. A companion volume, Immunopathology in Toxicology and Drug Development: Volume 2, Organ Systems, offers summaries of organ-specific immunobiology and immunopathology as well as common responses to xenobiotics. These informative and strategic books were created in response to the large segment of drug development that

Clinical Laboratory Animal Medicine

Clinical Laboratory Animal Medicine
  • Author : Lesley A. Colby,Megan H. Nowland,Lucy H. Kennedy
  • Publisher : John Wiley & Sons
  • Release : 11 October 2019
GET THIS BOOKClinical Laboratory Animal Medicine

The revised fifth edition of Clinical Laboratory Animal Medicine: An Introduction is an accessible guide to basic information for conducting animal research safely and responsibly. It includes a review of the unique anatomic and physiologic characteristics of laboratory animals, husbandry practices, and veterinary care of many animals frequently used in research, including rodents, rabbits, ferrets, zebrafish, nonhuman primates, and agricultural animals. The updated fifth edition adds two new chapters on zebrafish and large animals, new information on transgenic models and

Toxicologic Pathology

Toxicologic Pathology
  • Author : Pritam S. Sahota,James A. Popp,Jerry F. Hardisty,Chirukandath Gopinath,Page Bouchard
  • Publisher : CRC Press
  • Release : 31 August 2018
GET THIS BOOKToxicologic Pathology

Following the success of the first edition, this book is designed to provide practical and timely information for toxicologic pathologists working in pharmaceutical drug discovery and development. The majority of the book (Organ Systems) will provide detailed descriptions of histopathological lesions observed in drug development. In addition, it will provide information to assist the pathologist in making determinations of the origin of lesions as well as its relevance to human risk. Toxicologic Pathology: Nonclinical Safety Assessment, Second Edition includes 2 new

Medical and Surgical Management of Ocular Surface Disease in Exotic Animals, An Issue of Veterinary Clinics of North America: Exotic Animal Practice, Ebook

Medical and Surgical Management of Ocular Surface Disease in Exotic Animals, An Issue of Veterinary Clinics of North America: Exotic Animal Practice, Ebook
  • Author : Sarah L. Czerwinski
  • Publisher : Elsevier Health Sciences
  • Release : 21 November 2018
GET THIS BOOKMedical and Surgical Management of Ocular Surface Disease in Exotic Animals, An Issue of Veterinary Clinics of North America: Exotic Animal Practice, Ebook

This issue of Veterinary Clinics: Exotic Animal Practice, Guest Edited by Dr. Sarah Czerwinski, is devoted to the Medical and Surgical Management of Ocular Surface Disease in Exotic Animals. Dr. Czerwinski has assembled a list of articles that covers ocular surface disease in a wide range of animals, including: Rabbits; Rodents (Guinea pigs, mice, rats, and chinchillas); Ferrets; Marine mammals; Birds; New world camelids; Fish; Amphibians; and Reptiles (crocodilians, lizards, chelonians, and snakes).

Comparative Anatomy and Histology

Comparative Anatomy and Histology
  • Author : Piper M. Treuting,Suzanne M. Dintzis,Kathleen S. Montine
  • Publisher : Academic Press
  • Release : 29 August 2017
GET THIS BOOKComparative Anatomy and Histology

The second edition of Comparative Anatomy and Histology is aimed at the new rodent investigator as well as medical and veterinary pathologists who need to expand their knowledge base into comparative anatomy and histology. It guides the reader through normal mouse and rat anatomy and histology using direct comparison to the human. The side by side comparison of mouse, rat, and human tissues highlight the unique biology of the rodents, which has great impact on the validation of rodent models

Pathology of Genetically Engineered and Other Mutant Mice

Pathology of Genetically Engineered and Other Mutant Mice
  • Author : John P. Sundberg,Peter Vogel,Jerrold M. Ward
  • Publisher : John Wiley & Sons
  • Release : 26 January 2022
GET THIS BOOKPathology of Genetically Engineered and Other Mutant Mice

An updated and comprehensive reference to pathology in every organ system in genetically modified mice The newly revised and thoroughly updated Second Edition of Pathology of Genetically Engineered and Other Mutant Mice delivers a comprehensive resource for pathologists and biomedical scientists tasked with identifying and understanding pathologic changes in genetically modified mice. The book is organized by body system, includes descriptions and explanations of a wide range of findings, as well as hundreds of color photographs illustrating both common and

The Mouse Brain in Stereotaxic Coordinates

The Mouse Brain in Stereotaxic Coordinates
  • Author : George Paxinos,Keith B. J. Franklin
  • Publisher : Gulf Professional Publishing
  • Release : 19 August 2022
GET THIS BOOKThe Mouse Brain in Stereotaxic Coordinates

The Mouse Brain in Stereotaxic Coordinates, Second Edition has been the acknowledged reference in this field since the publication of the first edition, and is now available in a Compact Edition. This will provide a more affordable option for students, as well as researchers needing an additional lab atlas. This version includes the coronal diagrams delineating the entire brain as well as the introductory text from the Deluxe edition. It is an essential reference for anyone studying the mouse brain