Big Mechanisms in Systems Biology

Big Mechanisms in Systems Biology: Big Data Mining, Network Modeling, and Genome-Wide Data Identification explains big mechanisms of systems biology by system identification and big data mining methods using models of biological systems. Systems biology is currently undergoing revolutionary changes in response to the integration of powerful technologies. Faced with a large volume of available literature, complicated mechanisms, small prior knowledge, few classes on the topics, and causal and mechanistic language, this is an ideal resource. This book addresses system immunity, regulation, infection, aging, evolution, and carcinogenesis, which are complicated biological systems with inconsistent findings in existing resources. These inconsistencies may reflect the underlying biology time-varying systems and signal transduction events that are often context-dependent, which raises a significant problem for mechanistic modeling since it is not clear which genes/proteins to include in models or experimental measurements. The book is a valuable resource for bioinformaticians and members of several areas of the biomedical field who are interested in an in-depth understanding on how to process and apply great amounts of biological data to improve research. Written in a didactic manner in order to explain how to investigate Big Mechanisms by big data mining and system identification Provides more than 140 diagrams to illustrate Big Mechanism in systems biology Presents worked examples in each chapter

Produk Detail:

  • Author : Bor-Sen Chen
  • Publisher : Academic Press
  • Pages : 878 pages
  • ISBN : 0128097078
  • Rating : 4/5 from 21 reviews
CLICK HERE TO GET THIS BOOKBig Mechanisms in Systems Biology

Big Mechanisms in Systems Biology

Big Mechanisms in Systems Biology
  • Author : Bor-Sen Chen,Cheng-Wei Li
  • Publisher : Academic Press
  • Release : 25 October 2016
GET THIS BOOKBig Mechanisms in Systems Biology

Big Mechanisms in Systems Biology: Big Data Mining, Network Modeling, and Genome-Wide Data Identification explains big mechanisms of systems biology by system identification and big data mining methods using models of biological systems. Systems biology is currently undergoing revolutionary changes in response to the integration of powerful technologies. Faced with a large volume of available literature, complicated mechanisms, small prior knowledge, few classes on the topics, and causal and mechanistic language, this is an ideal resource. This book addresses system

Molecular Mechanisms of Autonomy in Biological Systems

Molecular Mechanisms of Autonomy in Biological Systems
  • Author : Tara Karimi
  • Publisher : Springer
  • Release : 28 July 2018
GET THIS BOOKMolecular Mechanisms of Autonomy in Biological Systems

This book presents a novel molecular description for understanding the regulatory mechanisms behind the autonomy and self-organization in biological systems. Chapters focus on defining and explaining the regulatory molecular mechanisms behind different aspects of autonomy and self-organization in the sense of autonomous coding, data processing, structure (mass) formation and energy production in a biological system. Subsequent chapters discuss the cross-talk among mechanisms of energy, and mass and information, transformation in biological systems. Other chapters focus on applications regarding therapeutic approaches

Globalization, Biosecurity, and the Future of the Life Sciences

Globalization, Biosecurity, and the Future of the Life Sciences
  • Author : National Research Council,Institute of Medicine,Board on Global Health,Policy and Global Affairs,Development, Security, and Cooperation,Committee on Advances in Technology and the Prevention of Their Application to Next Generation Biowarfare Threats
  • Publisher : National Academies Press
  • Release : 07 June 2006
GET THIS BOOKGlobalization, Biosecurity, and the Future of the Life Sciences

Biomedical advances have made it possible to identify and manipulate features of living organisms in useful ways--leading to improvements in public health, agriculture, and other areas. The globalization of scientific and technical expertise also means that many scientists and other individuals around the world are generating breakthroughs in the life sciences and related technologies. The risks posed by bioterrorism and the proliferation of biological weapons capabilities have increased concern about how the rapid advances in genetic engineering and biotechnology could

Systems Cancer Biology

Systems Cancer Biology
  • Author : Bor-Sen Chen
  • Publisher : Cambridge Scholars Publishing
  • Release : 13 July 2021
GET THIS BOOKSystems Cancer Biology

Cancer is a complex and heterogeneous (systematic) disease that exhibits high levels of robustness against various therapeutic interventions. Due to the complex, heterogeneous, and evolving nature of cancer, it is essential for a system-oriented view to be adopted in order to understand the pathogenic mechanism of cancer which will eventually lead to the drug discovery and treatment of patients. This book not only provides new insights from system modeling and large scale experimental data, but also will allow the reader

Systems Biology

Systems Biology
  • Author : Dimitrios Vlachakis
  • Publisher : BoD – Books on Demand
  • Release : 19 June 2019
GET THIS BOOKSystems Biology

Systems biology is the inevitable outcome of long years of knowledge acquisition and data accumulation. The aim of systems biology is to integrate in a seamless way all existing knowledge in interconnected disciplines, stretching from modern biomedical research to physics, chemistry, and mathematics. The main integration tool of such complex biomedical systems is via computational and mathematical modeling. In this direction, a series of state-of-the-art computer science techniques are used, namely, data mining and fusion, machine learning, and deep learning

Philosophy of Systems Biology

Philosophy of Systems Biology
  • Author : Sara Green
  • Publisher : Springer
  • Release : 15 December 2016
GET THIS BOOKPhilosophy of Systems Biology

The emergence of systems biology raises many fascinating questions: What does it mean to take a systems approach to problems in biology? To what extent is the use of mathematical and computational modelling changing the life sciences? How does the availability of big data influence research practices? What are the major challenges for biomedical research in the years to come? This book addresses such questions of relevance not only to philosophers and biologists but also to readers interested in the

Emerging Trends in Computational Biology, Bioinformatics, and Systems Biology

Emerging Trends in Computational Biology, Bioinformatics, and Systems Biology
  • Author : Hamid R Arabnia,Quoc Nam Tran
  • Publisher : Morgan Kaufmann
  • Release : 11 August 2015
GET THIS BOOKEmerging Trends in Computational Biology, Bioinformatics, and Systems Biology

Emerging Trends in Computational Biology, Bioinformatics, and Systems Biology discusses the latest developments in all aspects of computational biology, bioinformatics, and systems biology and the application of data-analytics and algorithms, mathematical modeling, and simu- lation techniques. • Discusses the development and application of data-analytical and theoretical methods, mathematical modeling, and computational simulation techniques to the study of biological and behavioral systems, including applications in cancer research, computational intelligence and drug design, high-performance computing, and biology, as well as cloud and grid

Computational Methods in Systems Biology

Computational Methods in Systems Biology
  • Author : Jérôme Feret,Heinz Koeppl
  • Publisher : Springer
  • Release : 06 October 2017
GET THIS BOOKComputational Methods in Systems Biology

This book constitutes the refereed proceedings of the 15th International Conference on Computational Methods in Systems Biology, CMSB 2017, held in Darmstadt, Germany, in September 2017. The 15 full papers, 4 tool papers and 4 posters presented together with 1 invited talk were carefully reviewed and selected from 41 regular paper submissions. Topics of interest include formalisms for modeling biological processes; models and their biological applications; frameworks for model verication, validation, analysis, and simulation of biological systems; high-performance computational systems biology and parallel implementations; model inference from

Systems Immunology and Infection Microbiology

Systems Immunology and Infection Microbiology
  • Author : Bor-Sen Chen
  • Publisher : Academic Press
  • Release : 15 March 2021
GET THIS BOOKSystems Immunology and Infection Microbiology

Systems Immunology and Infection Microbiology provides a large amount of biological system models, diagrams and flowcharts to illustrate the development procedure to understand the results of the systems immunology and infection microbiology. The results are not only remarkable, but also revolutionary in immunology and infection microbiology and can be also applied to systems drug design in infectious diseases.The book is divided into six parts. The first one discusses systems immunology; the second, systems infection microbiology; the third, systematic inflammation

Metabolome Analyses:

Metabolome Analyses:
  • Author : Seetharaman Vaidyanathan,George G. Harrigan,Royston Goodacre
  • Publisher : Springer Science & Business Media
  • Release : 28 April 2005
GET THIS BOOKMetabolome Analyses:

Metabolome analysis is now recognized as a crucial component of functional genomic and systems biology investigations. Innovative approaches to the study of metabolic regulation in microbial, plant and animal systems are increasingly facilitating the emergence of systems approaches in biology. This book highlights analytical and bioinformatics strategies now available for investigating metabolic networks in microbial, plant and animal systems. The contributing authors are world leaders in this field and they present an unambiguous case for pursuing metabolome analysis as a

Case Studies in Systems Biology

Case Studies in Systems Biology
  • Author : Pavel Kraikivski
  • Publisher : Springer
  • Release : 26 March 2021
GET THIS BOOKCase Studies in Systems Biology

This book provides case studies that can be used in Systems Biology related classes. Each case study has the same structure which answers the following questions: What is the biological problem and why is it interesting? What are the relevant details with regard to cell physiology and molecular mechanisms? How are the details put together into a mathematical model? How is the model analyzed and simulated? What are the results of the model? How do they compare to the known

Bioinformatics in the Era of Post Genomics and Big Data

Bioinformatics in the Era of Post Genomics and Big Data
  • Author : Ibrokhim Y. Abdurakhmonov
  • Publisher : BoD – Books on Demand
  • Release : 20 June 2018
GET THIS BOOKBioinformatics in the Era of Post Genomics and Big Data

Bioinformatics has evolved significantly in the era of post genomics and big data. Huge advancements were made toward storing, handling, mining, comparing, extracting, clustering and analysis as well as visualization of big macromolecular data using novel computational approaches, machine and deep learning methods, and web-based server tools. There are extensively ongoing world-wide efforts to build the resources for regional hosting, organized and structured access and improving the pre-existing bioinformatics tools to efficiently and meaningfully analyze day-to-day increasing big data. This