Biochemistry of Collagens Laminins and Elastin

Biochemistry of Collagens, Laminins, and Elastin: Structure, Function, and Biomarkers provides a comprehensive introduction to collagen and structural proteins. Type I collagen is one of the most abundant molecules in the body, playing essential roles in different tissues, particularly bone and skin. A key aspect of type I collagen is its post-translational modifications which are essential for correct synthesis and structural integrity of collagens, for tissue-specific functionality, as well as for application as biomarkers of different pathologies. This volume summarizes current data on key structural proteins (collagens, laminins and elastin), reviews how these molecules affect pathologies, and describes selected modifications of proteins that result in altered signaling properties of the original extracellular matrix component. Further, it discusses the novel concept that an increasing number of components of the ECM harbor cryptic signaling functions that may be viewed as endocrine functions. Additionally, it highlights how this knowledge can be exploited to modulate fibrotic disease. Provides a comprehensive introduction to collagen and structural proteins Provides insight into emerging analytical technologies that can detect biomarkers of extracellular matrix degradation Includes a chapter dedicated to the biomarkers of structural proteins Contains insights into the biochemical interactions and changes to structural composition of proteins in disease states

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  • Author : Morten Karsdal
  • Publisher : Academic Press
  • Pages : 272 pages
  • ISBN : 0128098996
  • Rating : 5/5 from 1 reviews
CLICK HERE TO GET THIS BOOKBiochemistry of Collagens Laminins and Elastin

Biochemistry of Collagens, Laminins and Elastin

Biochemistry of Collagens, Laminins and Elastin
  • Author : Morten Karsdal
  • Publisher : Academic Press
  • Release : 29 July 2016
GET THIS BOOKBiochemistry of Collagens, Laminins and Elastin

Biochemistry of Collagens, Laminins, and Elastin: Structure, Function, and Biomarkers provides a comprehensive introduction to collagen and structural proteins. Type I collagen is one of the most abundant molecules in the body, playing essential roles in different tissues, particularly bone and skin. A key aspect of type I collagen is its post-translational modifications which are essential for correct synthesis and structural integrity of collagens, for tissue-specific functionality, as well as for application as biomarkers of different pathologies. This volume summarizes

Biochemistry of Collagens, Laminins and Elastin

Biochemistry of Collagens, Laminins and Elastin
  • Author : Morten Karsdal
  • Publisher : Academic Press
  • Release : 28 May 2019
GET THIS BOOKBiochemistry of Collagens, Laminins and Elastin

There are 28 different collagens, with 46 unique chains, which allows for a collagen for each time and place. Some collagens are specialized for basement membrane, whereas others are the central structural component of the interstitial matrix. There are eight collagens among the 20 most abundant proteins in the body, which makes these molecules essential building blocks of tissues. In addition, lessons learned from monogenomic mutations in these proteins result in grave pathologies, exemplifying their importance in development. These molecules, and their post-translationally

The Extracellular Matrix: an Overview

The Extracellular Matrix: an Overview
  • Author : Robert Mecham
  • Publisher : Springer Science & Business Media
  • Release : 16 February 2011
GET THIS BOOKThe Extracellular Matrix: an Overview

Knowledge of the extracellular matrix (ECM) is essential to understand cellular differentiation, tissue development, and tissue remodeling. This volume of the series “Biology of Extracellular Matrix” provides a timely overview of the structure, regulation, and function of the major macromolecules that make up the extracellular matrix. It covers topics such as collagen types and assembly of collagen-containing suprastructures, basement membrane, fibronectin and other cell-adhesive glycoproteins, proteoglycans, microfibrils, elastin, fibulins and matricellular proteins, such as thrombospondin. It also explores the concept

Progress in Heritable Soft Connective Tissue Diseases

Progress in Heritable Soft Connective Tissue Diseases
  • Author : Jaroslava Halper
  • Publisher : Springer Science & Business Media
  • Release : 18 January 2014
GET THIS BOOKProgress in Heritable Soft Connective Tissue Diseases

This volume is a reference handbook focusing on diseases like Marfan syndrome, Ehlers-Danlos syndrome, Loeys-Dietz syndrome and other heritable soft connective tissue diseases. The book presents detailed information for both basic scientists and for clinicians seeing patients. It is also a stepping stone for new investigations and studies that goes beyond the facts about the composition and biochemistry of the connective tissue and extracellular matrix, as the authors connect individual components to specific aspects of various soft tissue disorders and

Methods in Extracellular Matrix Biology

Methods in Extracellular Matrix Biology
  • Author : Anonim
  • Publisher : Academic Press
  • Release : 05 January 2018
GET THIS BOOKMethods in Extracellular Matrix Biology

Methods in Extra Cellular Matrix, Volume 142, a new volume in the Methods in Cell Biology series, continues the legacy of this premier serial with quality chapters authored by leaders in the field. Unique to this updated volume are sections devoted to Elastin, Quantification of collagen and elastin, Fibrillins, Lysyl oxidase, Fibulins, Matrilins, Hyaluronic Acid, Small leucine-rich proteoglycans, Syndecans, Fibronectin, SPARC, Thrombospondins, Tenascins, Collagen IV, Multi-photon analysis of ECM, Cell-derived extracellular matrices, Laminins, Fibrillar Collagens, Imaging ECM in developing embryos, Analysis

Composition and Function of the Extracellular Matrix in the Human Body

Composition and Function of the Extracellular Matrix in the Human Body
  • Author : Francesco Travascio
  • Publisher : BoD – Books on Demand
  • Release : 15 June 2016
GET THIS BOOKComposition and Function of the Extracellular Matrix in the Human Body

The extracellular matrix (ECM) is an ensemble of non-cellular components present within all tissues and organs of the human body. The ECM provides structural support for scaffolding cellular constituents and biochemical and biomechanical support for those events leading to tissue morphogenesis, differentiation and homeostasis. Essential components of all ECMs are water, proteins and polysaccharides. However, their composition, architecture and bioactivity greatly vary from tissue to tissue in relation to the specific role the ECM is required to assume. This book

Calcific Aortic Valve Disease

Calcific Aortic Valve Disease
  • Author : Elena Aikawa
  • Publisher : BoD – Books on Demand
  • Release : 12 June 2013
GET THIS BOOKCalcific Aortic Valve Disease

Due to population aging, calcific aortic valve disease (CAVD) has become the most common heart valve disease in Western countries. No therapies exist to slow this disease progression, and surgical valve replacement is the only effective treatment. Calcific Aortic Valve Disease covers the contemporary understanding of basic valve biology and the mechanisms of CAVD, provides novel insights into the genetics, proteomics, and metabolomics of CAVD, depicts new strategies in heart valve tissue engineering and regenerative medicine, and explores current treatment

The Extracellular Matrix Factsbook

The Extracellular Matrix Factsbook
  • Author : Shirley Ayad,Ray Boot-Handford,Martin Humphries,Karl Kadler,Adrian Shuttleworth
  • Publisher : Elsevier
  • Release : 27 March 1998
GET THIS BOOKThe Extracellular Matrix Factsbook

The Second Edition of The Extracellular Matrix FactsBook has been completely revised, updated and expanded by over 50 percent. It contains over 85 entries on the diverse group of macromolecules that assemble toform the extracellular matrix. Entries provide information on molecular structure, isolation, primary structure, structural and functional sites, gene structure, database accession numbers, and key references. Key Features * Compiled by members of one of the foremost centers of matrix biochemistry in the world * Contains over 30 new entries, with all previous entries

Tissue Regeneration

Tissue Regeneration
  • Author : Hussein Abdelhay Essayed Kaoud
  • Publisher : BoD – Books on Demand
  • Release : 06 June 2018
GET THIS BOOKTissue Regeneration

Tissue regeneration is a vast subject, with many different important aspects to consider. Regenerative medicine is a new branch of medicine that tries to change the course of chronic diseases and, in many cases, regenerates the organ systems that fail due to age, disease, damage, or genetic defects. The main purpose of this book is to point out the interest of some important topics of tissue regeneration and the progress in this field as well as the variety of different

Decellularized Extracellular Matrix

Decellularized Extracellular Matrix
  • Author : Takashi Hoshiba,Tetsuji Yamaoka
  • Publisher : Royal Society of Chemistry
  • Release : 05 December 2019
GET THIS BOOKDecellularized Extracellular Matrix

Takashi Hoshiba and Tetsuji Yamaoka have brought together, for the first time, leading contributors to provide a fundamental guide to the decellularized extracelluar matrix. Focussing on the sources of dECM, preparation, characterization and applications of dECM in regenerative medicine and biological systems, this is a must-have resource for those working in regenerative medicine and tissue engineering.

Cardiac Extracellular Matrix

Cardiac Extracellular Matrix
  • Author : Eric G. Schmuck,Peiman Hematti,Amish N. Raval
  • Publisher : Unknown Publisher
  • Release : 24 July 2021
GET THIS BOOKCardiac Extracellular Matrix

This book on cardiac extracellular matrix (ECM) features three sections, Fundamental Science, Pre-Clinical and Translational Science, and Clinical Applications. In the Fundamental Science section, we will cover the spectrum of basic ECM science from ECM's role in development, biomechanical properties, cardiac ECM influence of cardiomyocyte biology, pathophysiology of ECM in heart disease, and ECM in tissue engineering. Section two, Preclinical and Translational Science, will discuss cardiac ECM technologies in the clinical pipeline including approaches to ECM as a therapeutic, animal

Muscle and Meat Biochemistry

Muscle and Meat Biochemistry
  • Author : A.M. Pearson
  • Publisher : Elsevier
  • Release : 02 December 2012
GET THIS BOOKMuscle and Meat Biochemistry

Muscle and Meat Biochemistry teaches the different concepts and topics under the eponymous subject. The book covers the gross and detailed composition and structure of muscles and the relationship of the nervous system with the muscular system; muscle cell differentiation and growth; proteins of the thick filament; and the molecular structure and enzymatic activity of myosin. The text also discusses the proteins found in the thin filament - actin, troponin, and myosin; skeletal muscle growth; protein metabolism; and fiber types.