Biofabrication

Biofabrication is a practical guide to the novel, inherently cross-disciplinary scientific field that focuses on biomanufacturing processes and a related range of emerging technologies. These processes and technologies ultimately further the development of products that may involve living (cells and/or tissues) and nonliving (bio-supportive proteins, scaffolds) components. The book introduces readers to cell printing, patterning, assembling, 3D scaffold fabrication, cell/tissue-on-chips as a coherent micro-/nano-fabrication toolkit. Real-world examples illustrate how to apply biofabrication techniques in areas such as regenerative medicine, pharmaceuticals and tissue engineering. In addition to being a vital reference for scientists, engineers and technicians seeking to apply biofabrication techniques, this book also provides an insight into future developments in the field, and potential new applications. Discover the multi-disciplinary toolkit provided by biofabrication and apply it to develop new products, techniques and therapies Covers a range of important emerging technologies in a coherent manner: cell printing, patterning, assembling, 3D scaffold fabrication, cell/tissue-on-chips... Readers develop the ability to apply biofabrication technologies through practical examples

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  • Author : Gabor Forgacs
  • Publisher : William Andrew
  • Pages : 288 pages
  • ISBN : 1455730041
  • Rating : 4/5 from 21 reviews
CLICK HERE TO GET THIS BOOKBiofabrication

Biofabrication

Biofabrication
  • Author : Gabor Forgacs,Wei Sun
  • Publisher : William Andrew
  • Release : 18 March 2013
GET THIS BOOKBiofabrication

Biofabrication is a practical guide to the novel, inherently cross-disciplinary scientific field that focuses on biomanufacturing processes and a related range of emerging technologies. These processes and technologies ultimately further the development of products that may involve living (cells and/or tissues) and nonliving (bio-supportive proteins, scaffolds) components. The book introduces readers to cell printing, patterning, assembling, 3D scaffold fabrication, cell/tissue-on-chips as a coherent micro-/nano-fabrication toolkit. Real-world examples illustrate how to apply biofabrication techniques in areas such as

Kenzan Method for Scaffold-Free Biofabrication

Kenzan Method for Scaffold-Free Biofabrication
  • Author : Koichi Nakayama
  • Publisher : Springer Nature
  • Release : 22 January 2021
GET THIS BOOKKenzan Method for Scaffold-Free Biofabrication

This is the first book about the “Kenzan” method for scaffold-free biofabrication, which does not rely on biomaterials as scaffolds to ensure correct multicellular spheroid positioning for building three dimensional construct only made from cells. The book explains the basic principles and concepts of the microneedle-based (“Kenzan”) method of building surgically-implantable tissue constructs using robotic cell spheroid-based three-dimensional bioprinting, a novel technology that opens up unique opportunities for the bioengineering of tissues and organs. First book on the novel Kenzan

Biofabrication

Biofabrication
  • Author : Joydip Kundu,Falguni Pati,Young Hun Jeong,Dong-Woo Cho
  • Publisher : Elsevier Inc. Chapters
  • Release : 18 March 2013
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Biomaterials have advanced from merely interacting with the body to controlling biological processes toward the goal of tissue regeneration. In order to reconstitute a new tissue or repair a damaged/diseased tissue, three components are critical for regenerative medicine or tissue engineering: cells, biomaterials as scaffold substrates, and growth factors. Thus, the design and selection of materials and the methods used for scaffold fabrication play a very important role in tissue engineering and regenerative medicine. Recent developments in biofabrication strategies

Biofabrication

Biofabrication
  • Author : Andrew M. Blakely,Jacquelyn Y. Schell,Adam P. Rago,Peter R. Chai,Anthony P. Napolitano,Jeffrey R. Morgan
  • Publisher : Elsevier Inc. Chapters
  • Release : 18 March 2013
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Scaffold-free tissue engineering approaches take advantage of cell–cell interactions, specifically the phenomena of self-assembly and self-sorting. By using micro-molded nonadhesive hydrogels, mono-dispersed cells can be seeded and directed to form spheroids as well as more complex shapes. These complex structures, including toroids, honeycombs, and loop-ended dogbones, bypass the critical diffusion distance required to maintain cell viability in culture over time. In addition, the formed microtissues are amenable to assays that analyze the self-assembly dynamics, the sorting of two different

Biofabrication

Biofabrication
  • Author : Bertrand Guillotin,Muhammad Ali,Alexandre Ducom,Sylvain Catros,Virginie Keriquel,Agnès Souquet,Murielle Remy,Jean-Christophe Fricain,Fabien Guillemot
  • Publisher : Elsevier Inc. Chapters
  • Release : 18 March 2013
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Laser-assisted bioprinting (LAB) is an emerging technology in the field of tissue engineering. Its physical mechanism makes it possible to print cells and liquid materials with a cell-level resolution. By giving tissue engineers control over cell density and organization of 3D tissue constructs, LAB holds much promise for fabricating living tissues with physiological functionality. After introducing the rationale of applying LAB to tissue engineering, we present exhaustively the physical parameters related to the laser-induced forward transfer technique (LIFT), which is

Biofabrication

Biofabrication
  • Author : Antonietta Messina,Loredana De Bartolo
  • Publisher : Elsevier Inc. Chapters
  • Release : 18 March 2013
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In tissue engineering the formation of organized and functional tissues is a very complex task: the cellular environment requires suitable physiological conditions that, presently, can be achieved and maintained by using properly designed biomaterials that can support the viability and all specific functions of cells. The creation of the biomimetic environment can be realized by using polymeric membranes with specific physico-chemical, morphological, and transport properties on the basis of the targeted tissue or organ. Membrane can act as an instructive

Biofabrication

Biofabrication
  • Author : Koichi Nakayama
  • Publisher : Elsevier Inc. Chapters
  • Release : 18 March 2013
GET THIS BOOKBiofabrication

In vitro fabrication of tissues and the regeneration of internal organs are no longer regarded as science fiction but as potential remedies for individuals suffering from chronic degenerative diseases. Tissue engineering has generated much interest from researchers in many fields, including cell and molecular biology, biomedical engineering, transplant medicine, and organic chemistry. Attempts to build tissues or organs in vitro have utilized both scaffold and scaffold-free approaches. Despite considerable progress, fabrication of three-dimensional tissue constructs in vitro remains a challenge.

Biofabrication

Biofabrication
  • Author : Qudus Hamid,Chengyang Wang,Jessica Snyder,Yu Zhao,Wei Sun
  • Publisher : Elsevier Inc. Chapters
  • Release : 18 March 2013
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Micro-electro-mechanical systems (MEMS) have revolutionized computation power due to their capabilities to develop advanced micro-architectures. MEMS technologies illustrate the potential for many applications in the field of tissue engineering, regenerative medicine, and life sciences. The fabrication of tissue models integrates the multidisciplinary field of life sciences and engineering. Presently, monolayer cell cultures are frequently used to investigate potential anticancer agents. These monolayer cultures give limited feedback on the effects of the microenvironment on chemotherapeutic and the heterogeneity of the tumor.

Biofabrication

Biofabrication
  • Author : Mohit P. Chhaya,Ferry P.W. Melchels,Paul S. Wiggenhauser,Jan T. Schantz,Dietmar W. Hutmacher
  • Publisher : Elsevier Inc. Chapters
  • Release : 18 March 2013
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Breast cancer is a major cause of illness for Australian women. Following tumour resection, breast reconstruction is undertaken for cosmetic and psychological reasons. Reconstruction using silicone-based implants leads to complications such as formation of a rigid fibrous tissue surrounding the implant giving a spherical and unnatural appearance to the breast. Reconstruction using autologous tissue is associated with donor site morbidity, tissue resorption and necrosis. Cell-based tissue engineering is an emerging approach to overcome these problems. Fully vascularised adipose tissue can

Biofabrication

Biofabrication
  • Author : Gulden Camci-Unal,Pinar Zorlutuna,Ali Khademhosseini
  • Publisher : Elsevier Inc. Chapters
  • Release : 18 March 2013
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Microscale hydrogels are potentially useful materials for controlling cellular behavior to mimic native microenvironments for tissue engineering applications. In this chapter, various fabrication techniques to generate microscale hydrogels and their applications in tissue engineering have been outlined. In addition, we provide examples of microscale hydrogels with different physical and chemical properties for generation of tissue constructs. Finally, we discuss potential future directions in fabrication of hydrogels to address challenges in tissue engineering. It is expected that these techniques will enable

Biofabrication

Biofabrication
  • Author : Yi Cheng,Yi Liu,Benjamin D. Liba,Reza Ghodssi,Gary W. Rubloff,William E. Bentley,Gregory F. Payne
  • Publisher : Elsevier Inc. Chapters
  • Release : 18 March 2013
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Integrated circuits transformed our lives, and the potential for integrating biology with devices promises even greater transformations. A key question is how to effectively interface biological and microfabricated systems. Our approach is to “biofabricate” the biology-device interface using biological materials and mechanisms. Here, we review recent progress on three biofabrication approaches: the use of stimuli-responsive materials to recognize device-imposed electrical inputs to direct the assembly (i.e., to electrodeposit) of hydrogels; the use of enzymes to build structure by conjugating

Biofabrication

Biofabrication
  • Author : U Kei Cheang,Min Jun Kim
  • Publisher : Elsevier Inc. Chapters
  • Release : 18 March 2013
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Recent developments in microrobotics demonstrate the potential to integrate microrobotic principles into drug delivery systems. Existing drug delivery technology is practically applicable for administrating pharmaceutical agents to targeted areas, but direct administration to targeted tissues and organs is still a great challenge. It is envisioned that the propulsive capability of microrobotic swimmers can enhance the targeting capability of current systems by providing specificity and minimizing side effects and complications for patients. The examination of the effective navigation of microorganisms in

Biofabrication

Biofabrication
  • Author : Pranav Soman,Shaochen Chen
  • Publisher : Elsevier Inc. Chapters
  • Release : 18 March 2013
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Natural tissues have complex structural hierarchy and biological heterogeneity. Tissue engineering utilizes biomaterial scaffolds to mimic various natural properties in order to augment regeneration therapies. Current tissue engineering techniques typically incorporate imprecise scaffold geometries with random cell placement. As a result, little can be known about the specific influences of controlled changes in 3D scaffold properties on cell behavior and therefore making the results less predictive of how cell behaves in a 3D environment. Digital micromirror-assisted projection printing (DMD-PP) technology

Essentials of 3D Biofabrication and Translation

Essentials of 3D Biofabrication and Translation
  • Author : Anthony Atala,James J Yoo
  • Publisher : Academic Press
  • Release : 17 July 2015
GET THIS BOOKEssentials of 3D Biofabrication and Translation

Essentials of 3D Biofabrication and Translation discusses the techniques that are making bioprinting a viable alternative in regenerative medicine. The book runs the gamut of topics related to the subject, including hydrogels and polymers, nanotechnology, toxicity testing, and drug screening platforms, also introducing current applications in the cardiac, skeletal, and nervous systems, and organ construction. Leaders in clinical medicine and translational science provide a global perspective of the transformative nature of this field, including the use of cells, biomaterials, and

Biofabrication and 3D Tissue Modeling

Biofabrication and 3D Tissue Modeling
  • Author : Dong-Woo Cho
  • Publisher : Royal Society of Chemistry
  • Release : 02 January 2019
GET THIS BOOKBiofabrication and 3D Tissue Modeling

3D tissue modelling is an emerging field used for the investigation of disease mechanisms and drug development. The two key drivers of this upsurge in research lie in its potential to offer a way to reduce animal testing with respect to biotoxicity analysis, preferably on physiology recapitulated human tissues and, additionally, provides an alternative approach to regenerative medicine. Integrating physics, chemistry, materials science, and stem cell and biomedical engineering, this book provides a complete foundation to this exciting, and interdisciplinary