Biological Chirality

Biological Chirality describes this occurrence, its history, and early research around the topic. The work covers analytical methods for observing the phenomenon, providing current techniques and practice and discussing the asymmetric morphology of certain living organisms, such as the position of the heart and liver in humans and the exceptions to biological homochirality seen in D-Amino Acids. In addition, it explores the requirement of enantioselectivity prepared pharmaceuticals to address enantioselectivities biomolecules, a major challenge in today's organic chemistry. Finally, the work considers the possible origin of biological homochirality, as well as the outlook for future research in this area. Describes the history of biological chirality research, its possible origins, and future exploration areas Discusses asymmetric exceptions in morphology and D-Amino Acids Explores the critical implications of enantioselective biomolecules for preparative organic chemistry with a goal of developing effective pharmaceuticals

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  • Author : Gyula Palyi
  • Publisher : Academic Press
  • Pages : 268 pages
  • ISBN : 0128123389
  • Rating : 4/5 from 21 reviews
CLICK HERE TO GET THIS BOOKBiological Chirality

Biological Chirality

Biological Chirality
  • Author : Gyula Palyi
  • Publisher : Academic Press
  • Release : 06 November 2019
GET THIS BOOKBiological Chirality

Biological Chirality describes this occurrence, its history, and early research around the topic. The work covers analytical methods for observing the phenomenon, providing current techniques and practice and discussing the asymmetric morphology of certain living organisms, such as the position of the heart and liver in humans and the exceptions to biological homochirality seen in D-Amino Acids. In addition, it explores the requirement of enantioselectivity prepared pharmaceuticals to address enantioselectivities biomolecules, a major challenge in today's organic chemistry. Finally, the

Progress in Biological Chirality

Progress in Biological Chirality
  • Author : Gyula Palyi,Claudia Zucchi,Luciano Caglioti
  • Publisher : Elsevier
  • Release : 13 December 2004
GET THIS BOOKProgress in Biological Chirality

Following on from Advances in BioChirality, Progress in Biological Chirality provides a unique summary and review of the most recent developments in the field of biochirality. Living organisms use only one enantiomer of chiral molecules in the majority of biologically important processes. The exact origin and mechanisms for this surprising selectivity are not yet known. This book discusses current research aimed at identifying the scientific reasons that may contribute to this phenomenon. Progress in Biological Chirality takes an interdisciplinary approach

Chirality in Biological Nanospaces

Chirality in Biological Nanospaces
  • Author : Nilashis Nandi
  • Publisher : CRC Press
  • Release : 27 July 2011
GET THIS BOOKChirality in Biological Nanospaces

Chirality is widely studied and omnipresent in biological molecules. However, how the retention of enantiomeric forms persists in many life processes without racemization is still unclear, and the molecular understanding of the stringent chiral specificity in enzymatic reactions is sparse. An overview of the influence of chirality in driving reactions within enzymatic cavities, Chirality in Biological Nanospaces: Reactions in Active Sites covers: Influences of molecular chirality on the structure of the active site and network of interactions to drive reactions

Chiral Drugs

Chiral Drugs
  • Author : Guo-Qiang Lin,Qi-Dong You,Jie-Fei Cheng
  • Publisher : John Wiley & Sons
  • Release : 08 August 2011
GET THIS BOOKChiral Drugs

An integrated view of chiral drugs—from concept and synthesisto pharmaceutical properties Chirality greatly influences a drug's biological and pharmacological properties. In an effort to achieve more predictable results from chiral drugs, the Food and Drug Administration now requires that these medicines be as pure as possible, which places great demands on drug synthesis, purification, analysis, and testing. To assist researchers in acquiring the essential knowledge to meet these rigid guidelines, Chiral Drugs focuses on three vital chiral technologies—asymmetric

Advances in BioChirality

Advances in BioChirality
  • Author : C. Zucchi,L. Caglioti,Gyula Palyi
  • Publisher : Elsevier
  • Release : 08 September 1999
GET THIS BOOKAdvances in BioChirality

Chirality is a fundamental, persistent, but often overlooked feature of all living organisms on the molecular level as well as on the macroscopic scale. The high degree of preference for only one of two possible mirror image forms in Nature, often called biological homochirality is a puzzling, and not yet fully understood, phenomenon. This book covers biological homochirality from an interdisciplinary approach - contributions range from synthetic chemists, theoretical topologists and physicists, from palaeontologists and biologists to space scientists and

On Chirality and the Universal Asymmetry

On Chirality and the Universal Asymmetry
  • Author : Georges H. Wagnière
  • Publisher : John Wiley & Sons
  • Release : 26 September 2008
GET THIS BOOKOn Chirality and the Universal Asymmetry

Until half a century ago, it was assumed that the forces of nature were symmetric and that they did not distinguish between right and left, between image and mirror image. The discovery of the violation of parity in 1956 was more than a sensation, for some it was a shock. It implied that the universe displays handedness, or chirality, and that it is fundamentally asymmetric. Remarkably, a most striking asymmetry is encountered in the realm of biology. Living organisms contain proteins

Aerospace Medicine and Biology

Aerospace Medicine and Biology
  • Author : Anonim
  • Publisher : Unknown Publisher
  • Release : 17 May 1984
GET THIS BOOKAerospace Medicine and Biology

A selection of annotated references to unclassified reports and journal articles that were introduced into the NASA scientific and technical information system and announced in Scientific and technical aerospace reports (STAR) and International aerospace abstracts (IAA).

Biochirality

Biochirality
  • Author : Pedro Cintas
  • Publisher : Springer
  • Release : 08 July 2014
GET THIS BOOKBiochirality

Early History of the Recognition of Molecular Biochirality, by Joseph Gal, Pedro Cintas Synthesis and Chirality of Amino Acids Under Interstellar Conditions, by Chaitanya Giri, Fred Goesmann, Cornelia Meinert, Amanda C. Evans, Uwe J. Meierhenrich Chemical and Physical Models for the Emergence of Biological Homochirality, by son E. Hein, Dragos Gherase, Donna G. Blackmond Biomolecules at Interfaces: Chiral, Naturally, by Arántzazu González-Campo and David B. Amabilino Stochastic Mirror Symmetry Breaking: Theoretical Models and Simulation of Experiments, by Celia

Chirality in Drug Design and Development

Chirality in Drug Design and Development
  • Author : Indra K. Reddy,Reza Mehvar
  • Publisher : CRC Press
  • Release : 15 March 2004
GET THIS BOOKChirality in Drug Design and Development

Covering every essential element in the development of chiral products, this reference provides a solid overview of the formulation, biopharmaceutical characteristics, and regulatory issues impacting the production of these pharmaceuticals. It supports researchers as they evaluate the pharmacodynamic, pharmacokinetic, and toxicological characteristics of specific enantiomers and chiral drug compounds and addresses in one convenient reference all the major challenges pertaining to drug chirality that have been neglected in the literature. Chirality in Drug Design and Development collects the latest studies

The Physical Origin of Homochirality in Life

The Physical Origin of Homochirality in Life
  • Author : David Cline
  • Publisher : American Institute of Physics
  • Release : 17 May 1996
GET THIS BOOKThe Physical Origin of Homochirality in Life

Annotation Papers from the February 1995 conference explore questions of the necessity of homochiral structure, the homochiral prebiotic medium hypothesis, the potential of homochirality to be used as a signature for existing or previous living systems beyond Earth, and experiments seeking to clarify the origin of homochirality. Contains sections on historical perspective, homochirality and life, models of physical chiral symmetry breaking, and future tests. For chemists, chemical physicists, and astrophysicists. No index. Annotation c. by Book News, Inc., Portland, Or.

Handbook of Chiral Chemicals, Second Edition

Handbook of Chiral Chemicals, Second Edition
  • Author : David Ager
  • Publisher : CRC Press
  • Release : 21 October 2005
GET THIS BOOKHandbook of Chiral Chemicals, Second Edition

As pharmaceutical companies look to develop single enantiomers as drug candidates, chemists are increasingly faced with the problems associated with this subclass of organic synthesis. "The Handbook of Chiral Chemicals, Second Edition" highlights the problems associated with the production of chiral compounds on a commercial scale. The handbook first elaborates upon starting materials obtained from a 'chiral pool', which can be derived from natural products. Then it explains methods and reactions that can introduce or influence stereogenic centers, particularly asymmetric