Biomarkers in Bipolar Disorders

Nearly 5.7 million adult Americans are affected by bipolar disorder according to the National Institute of Mental Health. Bipolar disorder (BD) is a recurrent chronic disorder characterized by fluctuations in mood. Those suffering from bipolar disorder are at crossroads, suffering a major personal, social and economic burden. Currently, there lacks of definitive diagnostic tools for psychiatric disorders. Psychiatry continues to rely on a non-biologically based, diagnostic classification. Identification of biologically relevant markers could improve the quality of life of patients with bipolar disorder and revolutionize public health. Biomarkers in Bipolar Disorders summarizes the cutting-edge findings in biomarkers research in Bipolar Disorders, emphasizing the most promising findings, tools and technologies relevant to drug development and personalized medicine. Key findings emphasizing different levels of evidence such as genes, molecules, cells, systems, brain and behavior related to diagnosis (state and trait/endophenotypes), prediction of treatment response and follow-up outcomes with as well as the most promising perspectives in each area are included in the book. Each section includes a comprehensive and focused overview on the state of the art and perspectives. The book concludes with a section on practical applications, encompassing diagnostics development (genetic testing, biomarkers), and new drug development. Edited by Dr. Rodrigo Machado-Vieira and Dr. Jair C. Soares, and contributed by leading experts in the field of biomarker research, this book will be become the leading tool for all researchers and clinicians in Bipolar Disorder. Describes strategies for biomarker discovery of relevant proteins differentially expressed in Bipolar Disorder Presents techniques and main findings in transcriptome research related to CNS synaptic function Provides an overview on the current behavioral strategies and their validity in drug development in Bipolar Disorder Discusses current genetic findings integrating tests for treatments leading to personalized treatments in the management of Bipolar Disorder

Produk Detail:

  • Author : Rodrigo Machado-Vieira
  • Publisher : Academic Press
  • Pages : 400 pages
  • ISBN : 9780128213988
  • Rating : 4/5 from 21 reviews
CLICK HERE TO GET THIS BOOKBiomarkers in Bipolar Disorders

Biomarkers in Bipolar Disorders

Biomarkers in Bipolar Disorders
  • Author : Rodrigo Machado-Vieira,Jair Soares
  • Publisher : Academic Press
  • Release : 15 October 2021
GET THIS BOOKBiomarkers in Bipolar Disorders

Nearly 5.7 million adult Americans are affected by bipolar disorder according to the National Institute of Mental Health. Bipolar disorder (BD) is a recurrent chronic disorder characterized by fluctuations in mood. Those suffering from bipolar disorder are at crossroads, suffering a major personal, social and economic burden. Currently, there lacks of definitive diagnostic tools for psychiatric disorders. Psychiatry continues to rely on a non-biologically based, diagnostic classification. Identification of biologically relevant markers could improve the quality of life of patients with

Biomarkers in Psychiatry

Biomarkers in Psychiatry
  • Author : Judith Pratt,Jeremy Hall
  • Publisher : Springer
  • Release : 05 January 2019
GET THIS BOOKBiomarkers in Psychiatry

This volume addresses one of the Holy Grails in Psychiatry, namely the evidence for and potential to adopt ‘Biomarkers’ for prevention, diagnosis, and treatment responses in mental health conditions. It meshes together state of the art research from international renowned pre-clinical and clinical scientists to illustrate how the fields of anxiety disorders, depression, psychotic disorders, and autism spectrum disorder have advanced in recent years.

Neurobiology of Bipolar Disorder

Neurobiology of Bipolar Disorder
  • Author : Joao Quevedo,Andre Ferrer Carvalho,Eduard Vieta
  • Publisher : Academic Press
  • Release : 25 November 2020
GET THIS BOOKNeurobiology of Bipolar Disorder

The Neurobiology of Bipolar Disorder: Road to Novel Therapeutics combines the basic neurobiology of bipolar disorder with discussions of the most recent advances in research, including the interacting pathways implicated in the pathophysiology of bipolar disorder, genetic approaches and the pharmacogenomics of bipolar disorder. The basic foundational understanding of the neurobiology underlying the disorder, along with a comprehensive summary of the most recent advances in research combine to aid advanced students and researchers in their understanding of bipolar disorder management

Biomarkers of Neurological and Psychiatric Disease

Biomarkers of Neurological and Psychiatric Disease
  • Author : Sabine Bahn,Paul Guest
  • Publisher : Academic Press
  • Release : 23 November 2011
GET THIS BOOKBiomarkers of Neurological and Psychiatric Disease

Published since 1959, International Review of Neurobiology is a well-known series appealing to neuroscientists, clinicians, psychologists, physiologists, and pharmacologists. Led by an internationally renowned editorial board, this important serial publishes both eclectic volumes made up of timely reviews and thematic volumes that focus on recent progress in a specific area of neurobiology research. This volume reviews existing theories and current research surrounding the movement disorder Dyskinesia. Leading authors review state-of-the-art in their field of investigation and provide their views and perspectives

Neuroprogression in Psychiatry

Neuroprogression in Psychiatry
  • Author : Flávio Kapczinski,Michael Berk,Pedro Vieira da Silva Magalhães
  • Publisher : Oxford University Press
  • Release : 05 March 2019
GET THIS BOOKNeuroprogression in Psychiatry

Recent studies regarding the neuropathology of specific neurological disorders suggest that both neurodevelopmental and neurodegenerative processes may play a role. However, in contrast to the neurodegeneration seen in neurological disorders such as Parkinson's and Alzheimer's disease, the term "neuroprogression" has been used to describe the neurodevelopmental aspect of pathological brain re-wiring that takes place in the context of severe psychiatric disorders, such as schizophrenia or bipolar disorder. Within psychiatry, patients with severe psychopathology, such as those depressed patients who eventually

Biomarkers of Postpartum Psychiatric Disorders

Biomarkers of Postpartum Psychiatric Disorders
  • Author : Jennifer L. Payne,Lauren M. Osborne
  • Publisher : Academic Press
  • Release : 28 September 2019
GET THIS BOOKBiomarkers of Postpartum Psychiatric Disorders

Biomarkers of Postpartum Psychiatric Disorders provides an up-to-date reference on the current research relating to biomarkers in psychiatric disorders, including major depressive disorder, OCD and bipolar disorder in the immediate postpartum time-period. It is the only reference on the market that synthesizes and interprets available data and reviews clinical phenotypes. Topics cover hormonal contributions, immunology, epigenetics and neuroimaging. While the risk of psychiatric illness during pregnancy appears to be equivalent to the risk at any other time in a woman’

Peripheral Brain-Derived Neurotrophic Factor (BDNF) As a Biomarker in Bipolar Disorder: a Meta-analysis of 52 Studies

Peripheral Brain-Derived Neurotrophic Factor (BDNF) As a Biomarker in Bipolar Disorder: a Meta-analysis of 52 Studies
  • Author : Vancouver Vancouver Press
  • Publisher : Unknown Publisher
  • Release : 20 December 2015
GET THIS BOOKPeripheral Brain-Derived Neurotrophic Factor (BDNF) As a Biomarker in Bipolar Disorder: a Meta-analysis of 52 Studies

The neurotrophic hypothesis postulates that mood disorders such as bipolar disorder (BD) are associated with a lower expression of brain-derived neurotrophic factor (BDNF). However, its role in peripheral blood as a biomarker of disease activity and of stage for BD, transcending pathophysiology, is still disputed. In the last few years an increasing number of clinical studies assessing BDNF in serum and plasma have been published. Therefore, it is now possible to analyse the association between BDNF levels and the severity

Biological Markers in Psychiatry and Neurology

Biological Markers in Psychiatry and Neurology
  • Author : Earl Usdin,Israel Hanin
  • Publisher : Elsevier
  • Release : 22 October 2013
GET THIS BOOKBiological Markers in Psychiatry and Neurology

Biological Markers in Psychiatry and Neurology is a collection of papers that details the advancement in the understanding of the biological markers that stems from psychiatric and neurological pathologies. The text first covers topics about various biological markers, such as neurochemical, enzymatic, membrane, receptors, endocrine, and physiological. Next, the selection examines the relationship between alcohol abuse and biological papers. The next part covers the genetic aspects of biological markers. The text also deals with use of tomography and modeling theory.

Mood Disorders

Mood Disorders
  • Author : Sudhakar Selvaraj,Paolo Brambilla,Jair C. Soares
  • Publisher : Cambridge University Press
  • Release : 07 January 2021
GET THIS BOOKMood Disorders

Offering up-to-date information on brain imaging in mood disorders, this book is an invaluable resource for mental health professionals.

Proteomic and Ionomic Study for Identification of Biomarkers in Biological Fluid Samples of Patients with Psychiatric Disorders and Healthy Individuals

Proteomic and Ionomic Study for Identification of Biomarkers in Biological Fluid Samples of Patients with Psychiatric Disorders and Healthy Individuals
  • Author : Jemmyson Romário de Jesus
  • Publisher : Springer Nature
  • Release : 22 October 2019
GET THIS BOOKProteomic and Ionomic Study for Identification of Biomarkers in Biological Fluid Samples of Patients with Psychiatric Disorders and Healthy Individuals

This book presents an exploratory analysis based on proteomic and ionomics studies comparing the blood serum of patients with bipolar disorder (BD), healthy controls, patients with schizophrenia (SCZ), and patients with other disorders (OD) in order to identify biomarkers of BD. Bipolar disorder is a psychiatric condition that affects thousands of people worldwide. The absence of biomarkers for BD has resulted in misdiagnosis and ineffective treatment in some patients, causing additional health problems and high costs for health systems. As

Biomarkers for Psychiatric Disorders

Biomarkers for Psychiatric Disorders
  • Author : Chris Turck
  • Publisher : Springer Science & Business Media
  • Release : 29 April 2009
GET THIS BOOKBiomarkers for Psychiatric Disorders

Biomarkers hold immense promise for the early detection of disease. Unlike other disorders like diabetes and heart disease where a limited number of biological markers are at hand that allow the physician to come up with a reliable diagnosis, there are currently no such markers available for affective disorders. As in any other disease area a major goal is therefore the identification of early markers that can categorize subsets of subjects in a consistent manner. This will allow a more

Reviews on Biomarker Studies in Psychiatric and Neurodegenerative Disorders

Reviews on Biomarker Studies in Psychiatric and Neurodegenerative Disorders
  • Author : Paul C. Guest
  • Publisher : Springer
  • Release : 12 February 2019
GET THIS BOOKReviews on Biomarker Studies in Psychiatric and Neurodegenerative Disorders

This book includes a series of reviews on general aspects of biomarker use in the study of psychiatric and neurodegenerative diseases and the development of medications involved in their treatment. It describes the pros and cons of the various approaches and covers the successes and failures in this research field. It is only by a thorough understanding of the shortcomings that progress can be made. The overall goal is to facilitate the understanding and treatment of these disorders, by providing