Biomarkers of Kidney Disease

A biomarker is a molecule that is measured as a marker of normal biological processes, disease processes or the response to a diagnostic or therapeutic intervention. Kidney diseases like acute kidney injury, chronic kidney disease, diabetic nephropathy, glomerular disease, renal cancer and preeclampsia still have a high morbidity. Measurement of biomarkers in the blood or urine that detect patients at risk of kidney diseases or that detect kidney diseases in the earliest stage may ultimately result in preventative or earlier or more effective treatments for kidney diseases. Biomarkers of Kidney Disease reviews the basic and clinical research on biomarkers of the common kidney diseases including acute kidney injury, chronic kidney disease, renal cancer, diabetic nephropathy, glomerular disease and preeclampsia. The characteristics of an ideal biomarker of kidney diseases and statistical analysis of biomarker studies is detailed. The latest techniques for biomarker detection like metabolomics and proteomics is covered in the book. This comprehensive book details the latest advances made in the field of biomarker research and development in kidney diseases. The book is an ideal companion for those interested in biomarker research and development, proteomics and metabolomics, kidney diseases, statistical analysis, transplantation and preeclampsia. Presents a comprehensive, translational source for all aspects of renal biomarkers in one reference work Experts in renal disease biomarkers (from all areas of academic and medical research) take readers from the bench research (cellular and molecular mechanism) to new therapeutic approaches

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  • Author : Charles L. Edelstein
  • Publisher : Academic Press
  • Pages : 454 pages
  • ISBN : 9780123756732
  • Rating : 4/5 from 21 reviews
CLICK HERE TO GET THIS BOOKBiomarkers of Kidney Disease

Biomarkers of Kidney Disease

Biomarkers of Kidney Disease
  • Author : Charles L. Edelstein
  • Publisher : Academic Press
  • Release : 27 October 2010
GET THIS BOOKBiomarkers of Kidney Disease

A biomarker is a molecule that is measured as a marker of normal biological processes, disease processes or the response to a diagnostic or therapeutic intervention. Kidney diseases like acute kidney injury, chronic kidney disease, diabetic nephropathy, glomerular disease, renal cancer and preeclampsia still have a high morbidity. Measurement of biomarkers in the blood or urine that detect patients at risk of kidney diseases or that detect kidney diseases in the earliest stage may ultimately result in preventative or earlier

Biomarker

Biomarker
  • Author : Ghousia Begum
  • Publisher : BoD – Books on Demand
  • Release : 05 September 2018
GET THIS BOOKBiomarker

This book investigates the emerging use of biomarkers as a diagnostic tool for the identification of patients with an abnormal condition or as a tool for staging the extent of disease, as an indicator of disease prognosis. Chapters in Part I focus on biomarkers for cancer, including breast cancer and pancreatic cancer, as well as circulating microRNA profiling in cancer biomarker discovery. Chapters in Part II focus on biomarkers of other diagnoses/diseases, including sepsis, childhood renal diseases, pulmonary diseases,

Advances in Nephropathy

Advances in Nephropathy
  • Author : Thomas Rath
  • Publisher : BoD – Books on Demand
  • Release : 24 October 2018
GET THIS BOOKAdvances in Nephropathy

Chronic kidney disease (CKD) is a world-wide known disease affecting up to 4% of the population with increasing figures in developing countries. Life expectancy of patients affected by CKD is shortened compared to the overall population and only a minority of patients reach end stage renal disease (ESRD) with the need for dialysis or renal transplantation; death overtakes dialysis. In nine chapters, this book focuses on different aspects related to the pathophysiology and clinical aspects of CKD, providing interesting insights into

Biomarkers in Drug Development

Biomarkers in Drug Development
  • Author : Michael R. Bleavins,Claudio Carini,Mallé Jurima-Romet,Ramin Rahbari
  • Publisher : John Wiley & Sons
  • Release : 20 September 2011
GET THIS BOOKBiomarkers in Drug Development

Discover how biomarkers can boost the success rate of drugdevelopment efforts As pharmaceutical companies struggle to improve the success rateand cost-effectiveness of the drug development process, biomarkershave emerged as a valuable tool. This book synthesizes and reviewsthe latest efforts to identify, develop, and integrate biomarkersas a key strategy in translational medicine and the drugdevelopment process. Filled with case studies, the bookdemonstrates how biomarkers can improve drug development timelines,lower costs, facilitate better compound selection, reducelate-stage attrition, and open the door

Urine Proteomics in Kidney Disease Biomarker Discovery

Urine Proteomics in Kidney Disease Biomarker Discovery
  • Author : Youhe Gao
  • Publisher : Springer
  • Release : 29 October 2014
GET THIS BOOKUrine Proteomics in Kidney Disease Biomarker Discovery

This book systematically summarizes the ideas and technologies used in urine proteome analysis. It argues that change is the core of biomarker definition since the body uses its homeostatic mechanisms to correct changes in the blood. This means that urine is probably a better source of biomarkers than blood. A roadmap to the urinary biomarker era is proposed, and researchers are reminded of the potential opportunities and risks in their study design. Kidney diseases are emphasized as they produce the

Chronic Kidney Disease

Chronic Kidney Disease
  • Author : Thomas Rath
  • Publisher : BoD – Books on Demand
  • Release : 21 February 2018
GET THIS BOOKChronic Kidney Disease

Known worldwide, chronic kidney disease (CKD) is a disease that affects up to 4% of the population with increasing figures also in the developing countries. Life expectancy of patients affected by CKD is shortened compared to the overall population, and only a minority of patients reach end-stage renal disease (ESRD) with the need for dialysis or renal transplantation; death overtakes dialysis. In the 13 chapters, this book sheds light on the different aspects related to pathophysiology and clinical aspects of CKD, providing

Transfusion Medicine for Pathologists

Transfusion Medicine for Pathologists
  • Author : Brian Castillo,Amitava Dasgupta,Kimberly Klein,Hlaing Tint,Amer Wahed
  • Publisher : Academic Press
  • Release : 29 June 2018
GET THIS BOOKTransfusion Medicine for Pathologists

Transfusion Medicine for Pathologists: A Comprehensive Review for Board Preparation, Certification, and Clinical Practice is a concise study guide designed to complement standard textbooks in the field of clinical pathology. Pathology residents and fellows of transfusion medicine will find this book useful as a preparation tool for their exams. In addition, the book is a valuable timesaver for busy residents looking for a focused and compact study guide on transfusion medicine that will also be ideal for practicing pathologists who

Acute kidney injury

Acute kidney injury
  • Author : Sics Editore
  • Publisher : SICS Editore
  • Release : 01 October 2014
GET THIS BOOKAcute kidney injury

In acute kidney injury (AKI) the ability of the glomeruli to filtrate deteriorates, which leads to a disturbed acid-base and fluid balance as well as to the accumulation of end products of nitrogen metabolism. Within 24 to 48 hours of the onset of the injury the serum creatinine concentration will rise and urine output fall. AKI should be identified before the creatinine concentration is markedly increased and the estimated glomerular filtration rate (eGFR) falls. A typical patient is an elderly individual with

Diseases of the Kidney and Urinary Tract

Diseases of the Kidney and Urinary Tract
  • Author : Robert W. Schrier
  • Publisher : Lippincott Williams & Wilkins
  • Release : 09 May 2021
GET THIS BOOKDiseases of the Kidney and Urinary Tract

The thoroughly updated Eighth Edition of this classic three-volume work provides the most comprehensive, current, and authoritative information on diseases of the kidney and urinary tract. This clinically oriented reference focuses on diagnosis and treatment of specific diseases, disorders, and complications and incorporates the basic science practicing physicians need to evaluate and manage the disease process. Each of the fourteen sections is written by internationally renowned contributors and provides coverage comparable to a complete book. The first two sections review

Updates in Hemodialysis

Updates in Hemodialysis
  • Author : Hiromichi Suzuki
  • Publisher : BoD – Books on Demand
  • Release : 09 September 2015
GET THIS BOOKUpdates in Hemodialysis

In this special issue, reviews of various aspects of HD therapy were submitted from all over the world. In particular, reviews for recent advances in this area from leading experts have been contributed to the book Hemodialysis. In order to deliver optimal patient care, nephrologists need to understand and be highly knowledgeable in the mechanisms of multiple aspects of hemodialysis therapy. Moreover, this book will provide an important source of information for beginners and experts, basic scientists and physicians who

Accelerating the Development of Biomarkers for Drug Safety

Accelerating the Development of Biomarkers for Drug Safety
  • Author : Institute of Medicine,Board on Health Sciences Policy,Forum on Drug Discovery, Development, and Translation
  • Publisher : National Academies Press
  • Release : 20 August 2009
GET THIS BOOKAccelerating the Development of Biomarkers for Drug Safety

Biomarkers can be defined as indicators of any biologic state, and they are central to the future of medicine. As the cost of developing drugs has risen in recent years, reducing the number of new drugs approved for use, biomarker development may be a way to cut costs, enhance safety, and provide a more focused and rational pathway to drug development. On October 24, 2008, the IOM's Forum on Drug Discovery, Development, and Translation held "Assessing and Accelerating Development of Biomarkers for

ADQI Consensus on AKI Biomarkers and Cardiorenal Syndromes

ADQI Consensus on AKI Biomarkers and Cardiorenal Syndromes
  • Author : J.A. Kellum,P.A. McCullough,R.L. Mehta,P.T. Murray,C. Ronco
  • Publisher : Karger Medical and Scientific Publishers
  • Release : 14 May 2013
GET THIS BOOKADQI Consensus on AKI Biomarkers and Cardiorenal Syndromes

Associated with both acute kidney injury (AKI) and cardio-renal syndromes (CRS), new biomarkers represent both a popular area of investigation and a new opportunity for advancement of therapy. This book contains the resolutions of the most recent ADQI conferences on biomarkers in AKI (Dublin) and on cardio-renal syndromes (Venice). The first part answers specific questions about new biomarkers and their use and utility in AKI: What are the most suitable candidate molecules and physiologic measures, how solid and evidence based

Renal Fibrosis: Mechanisms and Therapies

Renal Fibrosis: Mechanisms and Therapies
  • Author : Bi-Cheng Liu,Hui-Yao Lan,Lin-Li Lv
  • Publisher : Springer
  • Release : 09 August 2019
GET THIS BOOKRenal Fibrosis: Mechanisms and Therapies

This book systemically presents the latest research on renal fibrosis, covering all the major topics in the field, including the possible mechanisms, biomarkers, and strategies for prevention and treatment of chronic kidney disease (CKD). Due to its high prevalence, CKD represents a huge global economic and social burden. Irrespective of the initial causes, CKD progresses to end stage kidney disease (ESKD) due to renal fibrosis, which is characterized by glomerulosclerosis, tubule atrophy and atresia, and the excessive accumulation of extracellular