Breaking Tolerance to Pancreatic Cancer Unresponsiveness to Chemotherapy

Breaking Tolerance to Pancreatic Cancer Unresponsiveness to Chemotherapy edited by Dr. Nagaraju, PhD., DSc. focuses on overriding the resistance from chemotherapeutic drugs with a broader range of treatment options. It particularly focuses on stroma, tumor microenvironment, stem cells, stellate cells, transcription factors, growth factors, and important signaling pathways. This volume discusses topics such as pancreatic cancer biology, current therapeutic options, EMT, chemotherapy resistance mechanisms, and genetic manipulations and natural products to enhance the sensitivity of pancreatic cancer to chemotherapy. Additionally, it discusses small targeted molecules and pancreatic cancer trials, and nanotechnology-based drug delivery. Breaking Tolerance to Pancreatic Cancer Unresponsiveness to Chemotherapy is a valuable source for researchers and advanced students in cancer and oncology as well as clinicians and medical students who are interested in learning more about ways to break pancreatic cancer resistance to chemotherapy. Modulates the biologic properties of stroma in pancreatic cancer by targeting the several chemotherapy resistance mechanisms to impede their malignant property by introducing new strategies and drugs Provides information about on-going research as well as clinical data on pancreatic cancer and detailed descriptions about therapeutic options for easy understanding Utilizes full color figures to help the understanding of the content and tables for easy comparison of information as well as quick access to it

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  • Author : Ganji Purnachandra Nagaraju
  • Publisher : Academic Press
  • Pages : 223 pages
  • ISBN : 0128176628
  • Rating : 4/5 from 21 reviews
CLICK HERE TO GET THIS BOOKBreaking Tolerance to Pancreatic Cancer Unresponsiveness to Chemotherapy

Breaking Tolerance to Pancreatic Cancer Unresponsiveness to Chemotherapy

Breaking Tolerance to Pancreatic Cancer Unresponsiveness to Chemotherapy
  • Author : Ganji Purnachandra Nagaraju
  • Publisher : Academic Press
  • Release : 26 February 2019
GET THIS BOOKBreaking Tolerance to Pancreatic Cancer Unresponsiveness to Chemotherapy

Breaking Tolerance to Pancreatic Cancer Unresponsiveness to Chemotherapy edited by Dr. Nagaraju, PhD., DSc. focuses on overriding the resistance from chemotherapeutic drugs with a broader range of treatment options. It particularly focuses on stroma, tumor microenvironment, stem cells, stellate cells, transcription factors, growth factors, and important signaling pathways. This volume discusses topics such as pancreatic cancer biology, current therapeutic options, EMT, chemotherapy resistance mechanisms, and genetic manipulations and natural products to enhance the sensitivity of pancreatic cancer to chemotherapy. Additionally,

Theranostic Approach for Pancreatic Cancer

Theranostic Approach for Pancreatic Cancer
  • Author : Ganji Purnachandra Nagaraju,Sarfraz Ahmad
  • Publisher : Academic Press
  • Release : 19 August 2019
GET THIS BOOKTheranostic Approach for Pancreatic Cancer

Theranostic Approach for Pancreatic Cancer modulates the biologic properties of stroma in pancreatic cancer by targeting the several chemotherapy resistance mechanisms to impede their malignant property through introducing new strategies and drugs for tackling the disease. It brings information about ongoing research as well as clinical data about pancreatic cancer and provides detailed descriptions about diagnostic and therapeutic options for easy understanding. The book discusses several topics related to pancreatic cancer, such as stem cells, drug resistance and pancreatic tumor

A Theranostic and Precision Medicine Approach for Female-Specific Cancers

A Theranostic and Precision Medicine Approach for Female-Specific Cancers
  • Author : Rama Rao Malla,Ganji Purnachandra Nagaraju
  • Publisher : Academic Press
  • Release : 06 November 2020
GET THIS BOOKA Theranostic and Precision Medicine Approach for Female-Specific Cancers

A Theranostic and Precision Medicine Approach for Female-Specific Cancers provides information regarding ongoing research and clinical data surrounding female specific cancers (breast, cervical, ovarian and endometrial cancers). The book encompasses detailed descriptions about diagnostics and therapeutic options for easy understanding, focusing on the subject matter with a broader range of treatment options. In addition, it explores new theranostics, i.e., diagnostic, therapeutic and precision medicine strategies currently being developed for FSCs. This book is a valuable resource for cancer researchers,

Role of Tyrosine Kinases in Gastrointestinal Malignancies

Role of Tyrosine Kinases in Gastrointestinal Malignancies
  • Author : Ganji Purnachandra Nagaraju
  • Publisher : Springer
  • Release : 27 September 2018
GET THIS BOOKRole of Tyrosine Kinases in Gastrointestinal Malignancies

The aim of this book is to provide comprehensive overview of the role of different tyrosine kinases in the progression and metastasis of various cancers of the gastrointestinal tract such as esophagus, liver, pancreas, stomach, and colorectal. Activation of various signaling pathways and tyrosine kinases are responsible for resistance to chemo and radiotherapy in these gastrointestinal malignancies. Targeting these tyrosine kinases, which regulate the activities of survival pathways in growth, and metastasis is a rational strategy in gastrointestinal cancer therapy.

Molecular Mechanisms of Tumor Cell Resistance to Chemotherapy

Molecular Mechanisms of Tumor Cell Resistance to Chemotherapy
  • Author : Benjamin Bonavida
  • Publisher : Springer Science & Business Media
  • Release : 04 July 2013
GET THIS BOOKMolecular Mechanisms of Tumor Cell Resistance to Chemotherapy

​​​​​This volume gives the latest developments in on the mechanisms of cancer cell resistance to apoptotic stimuli, which eventually result in cancer progression and metastasis. One of the main challenges in cancer research is to develop new therapies to combat resistant tumors. The development of new effective therapies will be dependent on delineating the biochemical, molecular, and genetic mechanisms that regulate tumor cell resistance to cytotoxic drug-induced apoptosis. These mechanisms should reveal gene products that directly regulate resistance in order

Role of Nutraceuticals in Cancer Chemosensitization

Role of Nutraceuticals in Cancer Chemosensitization
  • Author : Anonim
  • Publisher : Academic Press
  • Release : 18 October 2017
GET THIS BOOKRole of Nutraceuticals in Cancer Chemosensitization

Role of Nutraceuticals in Chemoresistance to Cancer, Volume Two, focuses on nutraceuticals, the compounds derived from natural sources, which are usually multi-targeted as a means to overcome chemoresistance. This book discusses the role of several compounds related to nutraceuticals and chemoresistance, such as curcumin, resveratrol, indole 3-carbinol, tocotrienols, ursolic acid, fisetin, celastrol, gambogic, butein, catechins and silymarin. It is a valuable resource for cancer researchers, oncologists and members of several areas of the biomedical field who are interested in understanding

100 Cases in Clinical Medicine, Second Edition

100 Cases in Clinical Medicine, Second Edition
  • Author : John Rees,James Pattison,Gwyn Williams
  • Publisher : CRC Press
  • Release : 09 December 2011
GET THIS BOOK100 Cases in Clinical Medicine, Second Edition

100 Cases in Clinical Medicine is an indispensable revision tool for medical students preparing for clinical examinations or OSCEs. Using scenarios which mimic daily life, the cases will interest students in clinical problems and help them develop their clinical reasoning skills, with each case presenting details of a patient's medical history and the key findings of a clinical examination, together with initial investigation results for evaluation. Key questions then prompt the student to evaluate the patient, and reach a decision regarding

Onco-Nephrology E-Book

Onco-Nephrology E-Book
  • Author : Kevin W. Finkel,Mark Anthony Perazella,Eric P Cohen
  • Publisher : Elsevier Health Sciences
  • Release : 02 July 2019
GET THIS BOOKOnco-Nephrology E-Book

Kidney disease and cancer are frequent comorbidities that require specialized knowledge and expertise from both the nephrologist and the oncologist. Written by three pioneers in this growing subspecialty, Onco-Nephrology provides authoritative, definitive coverage of the mechanism and management of these two life-threatening diseases. This unique, single-volume resource covers current protocols and recommends management therapies to arrest kidney failure and allow oncologic treatments to continue and succeed. Addresses acute and chronic kidney diseases that develop from a variety of cancers. This

Anti-cancer Drugs

Anti-cancer Drugs
  • Author : Jasna Bankovic
  • Publisher : BoD – Books on Demand
  • Release : 07 December 2016
GET THIS BOOKAnti-cancer Drugs

We are in constant search for new therapeutic options to cure cancer. In this book, you can find out how scientists throughout the world deal with this problem. Readers will learn how to engage nature, chemical synthesis, and cell machinery to design new anticancer agents. Nature has already been very generous in providing us different compounds which are in widespread application. Starting from these resources, various synthetic processes are applied to create synthetic drugs which can be then obtained in

Essentials of Interventional Cancer Pain Management

Essentials of Interventional Cancer Pain Management
  • Author : Amitabh Gulati,Vinay Puttanniah,Brian M. Bruel,William S. Rosenberg,Joseph C. Hung
  • Publisher : Springer
  • Release : 28 December 2018
GET THIS BOOKEssentials of Interventional Cancer Pain Management

This text provides a comprehensive review and expertise on various interventional cancer pain procedures. The first part of the text addresses the lack of consistency seen in the literature regarding interventional treatment options for specific cancer pain syndromes. Initially, it discusses primary cancer and treatment-related cancer pain syndromes that physicians may encounter when managing cancer patients. The implementation of paradigms that can be used in treating specific groups of cancer such as breast cancer, follows. The remainder of the text

Molecular Therapies of Cancer

Molecular Therapies of Cancer
  • Author : Georg F. Weber
  • Publisher : Springer
  • Release : 22 July 2015
GET THIS BOOKMolecular Therapies of Cancer

Molecular Therapies of Cancer comprehensively covers the molecular mechanisms of anti-cancer drug actions in a comparably systematic fashion. While there is currently available a great deal of literature on anti-cancer drugs, books on the subject are often concoctions of invited review articles superficially connected to one another. There is a lack of comprehensive and systematic text on the topic of molecular therapies in cancer. A further deficit in the relevant literature is a progressive sub-specialization that typically limits textbooks on

How To Break Bad News

How To Break Bad News
  • Author : Robert Buckman
  • Publisher : University of Toronto Press
  • Release : 08 August 1992
GET THIS BOOKHow To Break Bad News

For many health care professionals and social service providers, the hardest part of the job is breaking bad news. The news may be about a condition that is life-threatening (such as cancer or AIDS), disabling (such as multiple sclerosis or rheumatoid arthritis), or embarrassing (such as genital herpes). To date medical education has done little to train practitioners in coping with such situations. With this guide Robert Buckman and Yvonne Kason provide help. Using plain, intelligible language they outline the

Metronomic Chemotherapy

Metronomic Chemotherapy
  • Author : Guido Bocci,Giulio Francia
  • Publisher : Springer
  • Release : 04 September 2014
GET THIS BOOKMetronomic Chemotherapy

This book analyzes all aspects of metronomic chemotherapy, a new approach involving low-dose, long-term, and frequently administered therapy that has preclinical and clinical activity in various tumors. After an opening section on the pharmacological bases of metronomic chemotherapy, including its antiangiogenic effects and impact on immunity, preclinical studies on various classes of drug are discussed. Clinical applications of metronomic chemotherapy in a wide variety of tumors are then addressed in detail, with description of the results of all published studies.

Nanocarriers for Cancer Diagnosis and Targeted Chemotherapy

Nanocarriers for Cancer Diagnosis and Targeted Chemotherapy
  • Author : Muhammad Raza Shah,Muhammad Imran,Shafi Ullah
  • Publisher : Elsevier
  • Release : 13 July 2019
GET THIS BOOKNanocarriers for Cancer Diagnosis and Targeted Chemotherapy

Nanocarriers for Cancer Diagnosis and Targeted Chemotherapy reviews the principles and applications of nanocarriers for targeted drug delivery. Drug targeting involves active and passive strategies that exploit both the use of ligands for interactions and the physical and chemical properties of nanocarriers and micro-environments at target sites. Multidrug resistance and adverse side effects associated with anticancer drugs have attracted greater scientific attention and led formulation scientists to specifically target these drugs to target sites. Nanocarriers like liposomes, niosomes, gold nanorods,

Essentials of Breast Surgery: A Volume in the Surgical Foundations Series E-Book

Essentials of Breast Surgery: A Volume in the Surgical Foundations Series E-Book
  • Author : Michael S. Sabel
  • Publisher : Elsevier Health Sciences
  • Release : 23 April 2009
GET THIS BOOKEssentials of Breast Surgery: A Volume in the Surgical Foundations Series E-Book

This new volume in the Surgical Foundations series delivers need-to-know, current information in breast surgery in an exceptionally economical and user-friendly format. Coverage encompasses everything from anatomy and physiology, evaluation of breast symptoms...to discussions of breast cancer risk and management of breast cancer, equipping you to face any challenge with confidence. Whether reviewing key material in preparation for a procedure or studying for the boards, this is an invaluable resource in training and practice. Presents coverage that encompasses anatomy