Breaking Tolerance to Pancreatic Cancer Unresponsiveness to Immunotherapy

Breaking Tolerance to Pancreatic Cancer Unresponsiveness to Immunotherapy discusses current treatment as well as treatment under investigation in pancreatic cancer. It brings information on how to combine current therapy with treatment under development and/or in clinical trials in order to be able to improve pancreatic cancer survival. Pancreatic cancer has a very low survival rate since it is discovered on late phase, when the patient already presents metastases and surgical options are limited. Currently, there are different modalities to treat pancreatic cancer, however its response has been poor and the toxicity of the treatment limits not only the survival rate, but also the patients that are able to get treated. This book reviews new modalities on basic research intending to reach the cure of pancreatic cancer, such as oncolytic viruses and Bi-specific T cell engager (BiTEs) as future clinical treatment, as well as discusses recent researches using those modalities as prospective combination therapy. The book is a valuable source for cancer researchers, oncologists and several members of medical and biomedical field who are interested in learning more about new therapies to treat pancreatic cancer. Reviews current situation of pancreatic cancer before discussing new modalities, so the reader gets knowledge on what it is available and on problems faced on its treatment currently Discusses oncolytic virus in pancreatic cancer use, mainly herpes and adenoviruses, the results obtained on basic research as well as in clinical trials Encompasses knowledge on Bi-specific T cell engager (BiTEs) focusing on its function, development and use on pancreatic cancer Brings information on combination therapies recently developed that allow lower dose of treatment, which means less side effect

Produk Detail:

  • Author : Kasuya Hideki
  • Publisher : Academic Press
  • Pages : 250 pages
  • ISBN : 9780128229149
  • Rating : 4/5 from 21 reviews
CLICK HERE TO GET THIS BOOKBreaking Tolerance to Pancreatic Cancer Unresponsiveness to Immunotherapy

Breaking Tolerance to Pancreatic Cancer Unresponsiveness to Immunotherapy

Breaking Tolerance to Pancreatic Cancer Unresponsiveness to Immunotherapy
  • Author : Kasuya Hideki,Itzel Bustos Villalobos
  • Publisher : Academic Press
  • Release : 15 January 2021
GET THIS BOOKBreaking Tolerance to Pancreatic Cancer Unresponsiveness to Immunotherapy

Breaking Tolerance to Pancreatic Cancer Unresponsiveness to Immunotherapy discusses current treatment as well as treatment under investigation in pancreatic cancer. It brings information on how to combine current therapy with treatment under development and/or in clinical trials in order to be able to improve pancreatic cancer survival. Pancreatic cancer has a very low survival rate since it is discovered on late phase, when the patient already presents metastases and surgical options are limited. Currently, there are different modalities to

Breaking Tolerance to Pancreatic Cancer Unresponsiveness to Chemotherapy

Breaking Tolerance to Pancreatic Cancer Unresponsiveness to Chemotherapy
  • Author : Ganji Purnachandra Nagaraju
  • Publisher : Academic Press
  • Release : 26 February 2019
GET THIS BOOKBreaking Tolerance to Pancreatic Cancer Unresponsiveness to Chemotherapy

Breaking Tolerance to Pancreatic Cancer Unresponsiveness to Chemotherapy edited by Dr. Nagaraju, PhD., DSc. focuses on overriding the resistance from chemotherapeutic drugs with a broader range of treatment options. It particularly focuses on stroma, tumor microenvironment, stem cells, stellate cells, transcription factors, growth factors, and important signaling pathways. This volume discusses topics such as pancreatic cancer biology, current therapeutic options, EMT, chemotherapy resistance mechanisms, and genetic manipulations and natural products to enhance the sensitivity of pancreatic cancer to chemotherapy. Additionally,

Immunotherapy in Resistant Cancer: From the Lab Bench Work to Its Clinical Perspectives

Immunotherapy in Resistant Cancer: From the Lab Bench Work to Its Clinical Perspectives
  • Author : Jorge Morales-Montor,Mariana Segovia-Mendoza
  • Publisher : Academic Press
  • Release : 14 October 2020
GET THIS BOOKImmunotherapy in Resistant Cancer: From the Lab Bench Work to Its Clinical Perspectives

Immunotherapy in Resistant Cancer: From the Lab Bench Work to Its Clinical Perspectives provides high level knowledge on detailed mechanisms of actions and biological interactions of different immune drugs, with an aim of offering researchers and clinicians cutting-edge therapies to overcome drug resistance. The book explains the latest immunotherapies for different types of cancer, helping users carry out research projects or create alternatives for drug development in the pharmaceutical industry. Topics discussed include the relationship between immunotherapy and macrophages, immune

Improving the Therapeutic Ratio in Head and Neck Cancer

Improving the Therapeutic Ratio in Head and Neck Cancer
  • Author : Anonim
  • Publisher : Academic Press
  • Release : 04 October 2019
GET THIS BOOKImproving the Therapeutic Ratio in Head and Neck Cancer

Improving the Therapeutic Ratio in Head and Neck Cancer provides a complete review of current approaches to modulating therapeutic sensitivity in head and neck cancer. It presents a broad background of current approaches and by highlighting the potential for clinical translational, introduces a roadmap for how to move promising preclinical findings into the clinic. The book discusses topics such as immunotherapy and molecularly targeted therapies in head and neck cancer, PI3k/mTOR pathway, autophagy inhibition to sensitize HNC to

Theranostic Approach for Pancreatic Cancer

Theranostic Approach for Pancreatic Cancer
  • Author : Ganji Purnachandra Nagaraju,Sarfraz Ahmad
  • Publisher : Academic Press
  • Release : 19 August 2019
GET THIS BOOKTheranostic Approach for Pancreatic Cancer

Theranostic Approach for Pancreatic Cancer modulates the biologic properties of stroma in pancreatic cancer by targeting the several chemotherapy resistance mechanisms to impede their malignant property through introducing new strategies and drugs for tackling the disease. It brings information about ongoing research as well as clinical data about pancreatic cancer and provides detailed descriptions about diagnostic and therapeutic options for easy understanding. The book discusses several topics related to pancreatic cancer, such as stem cells, drug resistance and pancreatic tumor

A Theranostic and Precision Medicine Approach for Female-Specific Cancers

A Theranostic and Precision Medicine Approach for Female-Specific Cancers
  • Author : Rama Rao Malla,Ganji Purnachandra Nagaraju
  • Publisher : Academic Press
  • Release : 06 November 2020
GET THIS BOOKA Theranostic and Precision Medicine Approach for Female-Specific Cancers

A Theranostic and Precision Medicine Approach for Female-Specific Cancers provides information regarding ongoing research and clinical data surrounding female specific cancers (breast, cervical, ovarian and endometrial cancers). The book encompasses detailed descriptions about diagnostics and therapeutic options for easy understanding, focusing on the subject matter with a broader range of treatment options. In addition, it explores new theranostics, i.e., diagnostic, therapeutic and precision medicine strategies currently being developed for FSCs. This book is a valuable resource for cancer researchers,

Cancer Immunotherapy at the Crossroads

Cancer Immunotherapy at the Crossroads
  • Author : James H. Finke,Ronald M. Bukowski
  • Publisher : Springer Science & Business Media
  • Release : 24 November 2003
GET THIS BOOKCancer Immunotherapy at the Crossroads

Leading investigators and clinicians detail the different mechanisms used by tumors to escape and impair the immune system and then spell out possible clinical strategies to prevent or reverse tumor-induced immune dysfunction. The authors review the mechanisms of immune dysfunction and evasion mechanisms in histologically diverse human tumors, focusing on tumor-induced molecular defects in T cells and antigen-presenting cells (dendritic cells and tumors), that may serve as biomarkers for patient prognosis. They discuss the means by which these immune functions

The Road from Nanomedicine to Precision Medicine

The Road from Nanomedicine to Precision Medicine
  • Author : Shaker A. Mousa,Raj Bawa,Gerald F. Audette
  • Publisher : CRC Press
  • Release : 13 January 2020
GET THIS BOOKThe Road from Nanomedicine to Precision Medicine

The enormous advances in nanomedicine and precision medicine in the past two decades necessitated this comprehensive reference, which can be relied upon by researchers, clinicians, pharmaceutical scientists, regulators, policymakers, and lawyers alike. This standalone, full-color resource broadly surveys innovative technologies and advances pertaining to nanomedicine and precision medicine. In addition, it addresses often-neglected yet crucial areas such as translational medicine, intellectual property law, ethics, policy, FDA regulatory issues, nano-nomenclature, and artificial nano-machines—all accomplished in a user-friendly, broad yet interconnected

Oncothermia: Principles and Practices

Oncothermia: Principles and Practices
  • Author : Andras Szasz,Nora Szasz,Oliver Szasz
  • Publisher : Springer Science & Business Media
  • Release : 23 November 2010
GET THIS BOOKOncothermia: Principles and Practices

Oncothermia is the next generation medical innovation that delivers selective, controlled and deep energy for cancer treatment. The basic principles for oncothermia stem from oncological hyperthermia, the oldest approach to treating cancer. Nevertheless, hyperthermia has been wrought with significant controversy, mostly stemming from shortcomings of controlled energy delivery. Oncothermia has been able to overcome these insufficiencies and prove to be a controlled, safe and efficacious treatment option. This book is the first attempt to elucidate the theory and practice of

Immunotherapy of Cancer

Immunotherapy of Cancer
  • Author : Yoshiyuki Yamaguchi
  • Publisher : Springer
  • Release : 22 February 2016
GET THIS BOOKImmunotherapy of Cancer

This timely book, published just as cancer immunotherapy comes of age, summarizes the rationale, present status, and future perspective for cancer immunotherapy. Included are explanations of the constitution of the immune system and immunocheckpoints, the mechanism of antigen presentation and recognition, valuable modalities, clinical trials and guidance, personalization, and biomarkers, all of which are essential for understanding the success of cancer immunotherapy. This innovative therapy has been investigated worldwide as the fourth line of cancer treatment after the standard treatments

Anti-cancer Drugs

Anti-cancer Drugs
  • Author : Jasna Bankovic
  • Publisher : BoD – Books on Demand
  • Release : 07 December 2016
GET THIS BOOKAnti-cancer Drugs

We are in constant search for new therapeutic options to cure cancer. In this book, you can find out how scientists throughout the world deal with this problem. Readers will learn how to engage nature, chemical synthesis, and cell machinery to design new anticancer agents. Nature has already been very generous in providing us different compounds which are in widespread application. Starting from these resources, various synthetic processes are applied to create synthetic drugs which can be then obtained in