Cancer and Noncoding RNAs

Cancer and Noncoding RNAs offers an in-depth exploration of noncoding RNAs and their role in epigenetic regulation of complex human disease, most notably cancer. In addition to examining microRNAs, this volume provides a unique evaluation of more recently profiled noncoding RNAs now implicated in carcinogenesis, including lncRNAs, piRNAs, circRNAs, and tRNAs, identifying differences in function between these noncoding RNAs and how they interact with the rest of the epigenome. A broad range of chapters from experts in the field detail epigenetic regulation of various cancer types, along with recent next generation sequencing technologies, genome-wide association studies (GWAS) and bioinformatics approaches. This book will help researchers in genomic medicine and cancer biology better understand the role of noncoding RNAs in epigenetics, aiding in the development of useful biomarkers for diagnosis, prognosis and new RNA-based disease therapies. Provides a comprehensive analysis of noncoding RNAs implicated in epigenetic regulation of gene expression and chromatin dynamics Educates researchers and graduate students by highlighting, in addition to miRNAs, a range of noncoding RNAs newly associated with carcinogenesis Applies current knowledge of noncoding RNAs and epigenomics towards developing cancer and RNA-based disease therapies Features contributions by leading experts in the field

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  • Author : Jayprokas Chakrabarti
  • Publisher : Academic Press
  • Pages : 576 pages
  • ISBN : 0128134372
  • Rating : 5/5 from 1 reviews
CLICK HERE TO GET THIS BOOKCancer and Noncoding RNAs

Cancer and Noncoding RNAs

Cancer and Noncoding RNAs
  • Author : Jayprokas Chakrabarti,Sanga Mitra
  • Publisher : Academic Press
  • Release : 13 October 2017
GET THIS BOOKCancer and Noncoding RNAs

Cancer and Noncoding RNAs offers an in-depth exploration of noncoding RNAs and their role in epigenetic regulation of complex human disease, most notably cancer. In addition to examining microRNAs, this volume provides a unique evaluation of more recently profiled noncoding RNAs now implicated in carcinogenesis, including lncRNAs, piRNAs, circRNAs, and tRNAs, identifying differences in function between these noncoding RNAs and how they interact with the rest of the epigenome. A broad range of chapters from experts in the field detail

Physiologic and Pathologic Angiogenesis

Physiologic and Pathologic Angiogenesis
  • Author : Dan Simionescu,Agneta Simionescu
  • Publisher : BoD – Books on Demand
  • Release : 05 April 2017
GET THIS BOOKPhysiologic and Pathologic Angiogenesis

The purpose of this book is to highlight novel advances in the field and to incentivize scientists from a variety of fields to pursue angiogenesis as a research avenue. Blood vessel formation and maturation to capillaries, arteries, or veins is a fascinating area which can appeal to multiple scientists, students, and professors alike. Angiogenesis is relevant to medicine, engineering, pharmacology, and pathology and to the many patients suffering from blood vessel diseases and cancer, among others. We are hoping that

Clinical Applications of Non-Coding RNAs in Cancer

Clinical Applications of Non-Coding RNAs in Cancer
  • Author : Subash Gupta,Kishore Challagundla
  • Publisher : Elsevier
  • Release : 11 February 2022
GET THIS BOOKClinical Applications of Non-Coding RNAs in Cancer

Clinical Applications of Non-Coding RNAs in Cancer summarizes the existing strategies, advances and future opportunities on the role of non-coding RNAs in cancer patients. Established clinicians and researchers from all around the world share their views and expertise and provide readers with invaluable knowledge on the subject. This book provides a comprehensive collection of information on the utility of non-coding RNAs in the diagnosis, prognosis and therapy of cancer. It also discusses the evolutionary significance of non-coding RNAs and how

Non-coding RNAs and Cancer

Non-coding RNAs and Cancer
  • Author : Muller Fabbri
  • Publisher : Springer Science & Business Media
  • Release : 28 October 2013
GET THIS BOOKNon-coding RNAs and Cancer

The discovery of microRNAs and its role as gene expression regulators in human carcinogenesis represents one of the most important scientific achievements of the last decade. More recently, other non-coding RNAs have been discovered and its implications in cancer are emerging as well, suggesting a broader than anticipated involvement of the non-coding genome in cancer. Moreover, completely new and unexpected functions for microRNAs are being revealed, leading to the identification of new anticancer molecular targets. This book represents a comprehensive

Long Non Coding RNA Biology

Long Non Coding RNA Biology
  • Author : M.R.S. Rao
  • Publisher : Springer
  • Release : 16 August 2017
GET THIS BOOKLong Non Coding RNA Biology

This contributed volume offers a comprehensive and detailed overview of the various aspects of long non-coding RNAs and discusses their emerging significance. Written by leading experts in the field, it motivates young researchers around the globe, and offers graduate and postgraduate students fascinating insights into genes and their regulation in eukaryotes and higher organisms.

Gene Expression Profiling in Cancer

Gene Expression Profiling in Cancer
  • Author : Dimitrios Vlachakis
  • Publisher : BoD – Books on Demand
  • Release : 19 June 2019
GET THIS BOOKGene Expression Profiling in Cancer

The contribution of modern-day genetics in designing efficient gene expression profiles for cancer is immense. The progress of technology and science in recent years provides the opportunity for discovery and application of new techniques for treating various diseases that affect humanity. Methods for finding and analyzing the profile of gene expression of infected cells give scientists the ability to develop more targeted and effective treatments, especially for diseases such as cancer. The development of gene expression profiling is one of

Osteosarcoma

Osteosarcoma
  • Author : Matthew Gregory Cable,Robert Lawrence Randall
  • Publisher : BoD – Books on Demand
  • Release : 04 December 2019
GET THIS BOOKOsteosarcoma

This book is titled Osteosarcoma - Diagnosis, Mechanisms, and Translational Developments, and focuses on recent advancements and novel ideas in osteosarcoma research. In a manner of speaking, we have taken the multidisciplinary mindset essential for treating osteosarcoma and broadened it to include other areas of cancer research. By learning from gains in other areas of oncology, such as new lncRNAs, the understanding of cancer metabolism and oxidative phosphorylation, and new chemotherapy agents, we can apply them to the niche of

Roles of MicroRNAs and Other Noncoding RNAs in Cancer

Roles of MicroRNAs and Other Noncoding RNAs in Cancer
  • Author : Applied Research Applied Research Press
  • Publisher : Unknown Publisher
  • Release : 05 November 2015
GET THIS BOOKRoles of MicroRNAs and Other Noncoding RNAs in Cancer

MicroRNAs (miRNAs) are short, noncoding RNAs that bind mRNAs through partial base-pair complementarity with their target genes, resulting in post-transcriptional repression of gene expression. This thematic series delves into the cancer-specific functions of miRNAs and other noncoding RNAs, including lncRNAs, piRNAs, and ceRNAs, as well as RNAi. While many miRNAs have been shown to play a role in various cancers, other noncoding RNAs have only recently been identified to play a role, as well. Proposed and validated functions are discussed

Long Non-Coding RNAs in Cancer

Long Non-Coding RNAs in Cancer
  • Author : Alfons Navarro
  • Publisher : Unknown Publisher
  • Release : 15 August 2022
GET THIS BOOKLong Non-Coding RNAs in Cancer

This volume presents techniques needed for the study of long non-coding RNAs (lncRNAs) in cancer from their identification to functional characterization. Chapters guide readers through identification of lncRNA expression signatures in cancer tissue or liquid biopsies by RNAseq, single Cell RNAseq, Phospho RNAseq or Nanopore Sequencing techniques; validation of lncRNA signatures by Real time PCR, digital PCR or in situ hybridization; and functional analysis by siRNA or CRISPR based methods for lncRNA silencing or overexpression. Lipid based nanoparticles for delivery

The Long and Short Non-coding RNAs in Cancer Biology

The Long and Short Non-coding RNAs in Cancer Biology
  • Author : Erwei Song
  • Publisher : Springer
  • Release : 04 July 2016
GET THIS BOOKThe Long and Short Non-coding RNAs in Cancer Biology

The book conveys a comprehensive knowledge of long and short ncRNAs in cancer regulation and their potentials as diagnostic biomarkers and therapeutic targets. Topics covered include the molecular mechanisms of various classes of ncRNAs (with emphasis on long non-coding RNAs and microRNAs) in cancer, the functional roles of ncRNAs in regulating different cancer hallmarks (including proliferation, apoptosis, stem-cell properties, epithelial-mesenchymal transition, metabolism, angiogenesis, tumor-host interactions and therapeutic resistance), the role of ncRNAs in regulating cancer signaling circuitry programs (highlighting their

Cancer Genomics

Cancer Genomics
  • Author : Hui Ling,George A. Calin
  • Publisher : Elsevier Inc. Chapters
  • Release : 21 November 2013
GET THIS BOOKCancer Genomics

The discovery of microRNA (miRNA) involvement in cancer a decade ago, and the more recent findings of long non-coding RNAs in human diseases, challenged the long-standing view that RNAs without protein-coding potential are simply “junk” transcription within the human genome. These findings evidently changed the dogma that “DNA makes RNA makes protein” by showing that RNAs themselves can be essential regulators of cellular function and play key roles in cancer development. MiRNAs are evolutionarily conserved short single-stranded transcripts of 19–24 nucleotides

Non-Coding RNAs

Non-Coding RNAs
  • Author : Lütfi Tutar,Sumer Aras,Esen Tutar
  • Publisher : BoD – Books on Demand
  • Release : 04 March 2020
GET THIS BOOKNon-Coding RNAs

Noncoding RNAs (ncRNAs) are an attractive research field in the RNA world. ncRNAs play important roles in regulating gene expression in animals, plants, and various human diseases. It is clear that current and further research on ncRNAs will change our knowledge of the nature of genome composition by editing previous dogmas. This book provides an overview of current knowledge on ncRNA research by dealing with miRNA and ncRNA-related human diseases, plant miRNA markers, and the roles of lncRNAs in cancer

Non-coding RNAs in Cardiovascular Diseases

Non-coding RNAs in Cardiovascular Diseases
  • Author : Junjie Xiao
  • Publisher : Springer Nature
  • Release : 13 April 2020
GET THIS BOOKNon-coding RNAs in Cardiovascular Diseases

This book presents the latest research on non-coding RNAs in cardiovascular disease, a major cause of death worldwide. Non-coding RNAs play a significant role in development, proliferation, differentiation and apoptosis. Since altered non-coding RNA expression is often associated with various diseases, their potential use in diagnostics, prognostics and therapeutics is an important current area of study. The book consists of six parts: 1) An overview of non-coding RNAs and cardiovascular system, 2) Bioinformatics and interactions, 3) Non-coding RNA regulation in cardiovascular system, 4) Non-coding