Carbonic Anhydrases As Biocatalysts

Carbonic anhydrases (CAs, EC 4.2.1.1) are ubiquitous metalloenzymes, present throughout most living organisms and encoded by five evolutionarily unrelated gene families. The Carbonic Anhydrases as Biocatalysts: From Theory to Medical and Industrial Applications presents information on the growing interest in the study of this enzyme family and their applications to both medicine and biotechnology. Offers comprehensive coverage of the carbonic anhydrases enzyme family and their properties as biocatalysts Includes current applications of carbonic anhydrases in biotechnology on the basis of their catalytic efficiency, including new technologies for CO2 capture processes Identifies new targets for drug design studies Provides a selectivity profile for the different carbonic anhydrases and their related biomedical applications

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  • Author : Claudiu T. Supuran
  • Publisher : Elsevier
  • Pages : 398 pages
  • ISBN : 9780444632586
  • Rating : 4/5 from 21 reviews
CLICK HERE TO GET THIS BOOKCarbonic Anhydrases As Biocatalysts

Carbonic Anhydrases As Biocatalysts

Carbonic Anhydrases As Biocatalysts
  • Author : Claudiu T. Supuran,Giuseppina De Simone
  • Publisher : Elsevier
  • Release : 08 January 2015
GET THIS BOOKCarbonic Anhydrases As Biocatalysts

Carbonic anhydrases (CAs, EC 4.2.1.1) are ubiquitous metalloenzymes, present throughout most living organisms and encoded by five evolutionarily unrelated gene families. The Carbonic Anhydrases as Biocatalysts: From Theory to Medical and Industrial Applications presents information on the growing interest in the study of this enzyme family and their applications to both medicine and biotechnology. Offers comprehensive coverage of the carbonic anhydrases enzyme family and their properties as biocatalysts Includes current applications of carbonic anhydrases in biotechnology on the basis of their

Carbonic Anhydrases as Biocatalysts

Carbonic Anhydrases as Biocatalysts
  • Author : Claudiu T Supuran,Giuseppina De Simone
  • Publisher : Elsevier
  • Release : 14 January 2015
GET THIS BOOKCarbonic Anhydrases as Biocatalysts

Carbonic anhydrases (CAs, EC 4.2.1.1) are ubiquitous metalloenzymes, present throughout most living organisms and encoded by five evolutionarily unrelated gene families. The Carbonic Anhydrases as Biocatalysts: From Theory to Medical and Industrial Applications presents information on the growing interest in the study of this enzyme family and their applications to both medicine and biotechnology. Offers comprehensive coverage of the carbonic anhydrases enzyme family and their properties as biocatalysts Includes current applications of carbonic anhydrases in biotechnology on the basis of their

Carbonic Anhydrases

Carbonic Anhydrases
  • Author : Claudiu Supuran,Alessio Nocentini
  • Publisher : Academic Press
  • Release : 17 July 2019
GET THIS BOOKCarbonic Anhydrases

Carbonic Anhydrases provides an interdisciplinary review of the burgeoning carbonic anhydrase (CA) research area, spanning from CAs classification (biochemical and structural features) to drug design and pharmacology of CA inhibitors and activators, finally touching on the biotechnological applications of these metalloenzymes. The book adopts a clear step-by-step approach and introduction to this intricate and highly interdisciplinary field. A diverse range of chapters from international experts speak to CA classification and distribution, the mechanisms of action and drug design of inhibitors

Carbonic Anhydrases and Metabolism

Carbonic Anhydrases and Metabolism
  • Author : Claudiu T. Supuran
  • Publisher : MDPI
  • Release : 08 April 2019
GET THIS BOOKCarbonic Anhydrases and Metabolism

Carbonic anhydrases (CAs; EC 4.2.1.1) are metalloenzymes present in all kingdoms of life, as they equilibrate the reaction between three simple but essential chemical species: CO2, bicarbonate, and protons. Discovered more than 80 years ago, in 1933, these enzymes have been extensively investigated due to the biomedical application of their inhibitors, but also because they are an extraordinary example of convergent evolution, with seven genetically distinct CA families that evolved independently in Bacteria, Archaea, and Eukarya. CAs are also among the most efficient

Neutron Crystallography in Structural Biology

Neutron Crystallography in Structural Biology
  • Author : Peter Moody
  • Publisher : Academic Press
  • Release : 01 March 2020
GET THIS BOOKNeutron Crystallography in Structural Biology

Neutron Crystallography in Structural Biology, Volume 634, the latest volume in the Methods in Enzymology series, continues the legacy of this premier serial with quality chapters authored by leaders in the field. Chapters in this updated release include Fundamentals of neutron crystallography, Preparation of deuterated and perdeuterated proteins, Large crystal growth for neutron protein crystallography, Monochromatic - BIODIFF at FRM-II, Quasi-Laue 2 - IMAGINE at HIFER, Qusai-Laue 3 DALI (LADI-IIIB at ILL) -Narrow bandpass, Short wavelength - D19 at ILL, MaNDi at SNS,

Carbon Utilization

Carbon Utilization
  • Author : Malti Goel,M. Sudhakar
  • Publisher : Springer
  • Release : 28 March 2017
GET THIS BOOKCarbon Utilization

This book provides in-depth information on topics relating to anthropogenic carbon dioxide utilization processes. Presenting a collection of state-of-the-art scientific reviews and research perspectives on carbon management strategies of relevance to the energy industry, it features contributions by leading scientists and technocrats across 19 chapters as an Indian contribution In the energy industry, new processes for carbon dioxide removal and recycling are developing quickly, and it is in this context that the book provides an opportunity to review the current status

Pharmaceutical Biocatalysis

Pharmaceutical Biocatalysis
  • Author : Peter Grunwald
  • Publisher : CRC Press
  • Release : 27 June 2019
GET THIS BOOKPharmaceutical Biocatalysis

This book provides an overview of the world market of therapeutic enzymes and enzyme inhibitors, rare diseases, orphan drugs, the costs of drug development and therapies, and enzymes in downstream processing of pharmaceuticals. It discusses carbonic anhydrase inhibitors and their multiple drug interactions, carboxylesterase inhibitors for pharmaceutical applications, employment of inhibitors for the treatment of neurodegenerative diseases, use of engineered proteins, bioactive peptides, and fibrinolytic enzymes for thrombolytic therapy, and enzymes important for the design and development of new drugs/

Climate Change and Green Chemistry of CO2 Sequestration

Climate Change and Green Chemistry of CO2 Sequestration
  • Author : Malti Goel,T. Satyanarayana,Maruthadu Sudhakar,D. P. Agrawal
  • Publisher : Springer Nature
  • Release : 10 May 2021
GET THIS BOOKClimate Change and Green Chemistry of CO2 Sequestration

The book comprises state-of-the-art scientific reviews on carbon management strategies in response to climate change. It provides in-depth information on topics relating to recent advances in carbon capture technology and its reuse in value added products. It features contributions of leading scientists and technocrats on topics including climate change and carbon sequestration, lowering carbon footprint CO2 capture, low carbon imperatives in oil industry, CO2 as refrigerant in cold-chain application, carbonic anhydrase-mediated carbon sequestration and utilization, chemical looping combustion with Indian

Biocatalytic Performance of Carbonic Anhydrase Immobilized Within Polyurethane Foam in Water-miscible Organic Solvents

Biocatalytic Performance of Carbonic Anhydrase Immobilized Within Polyurethane Foam in Water-miscible Organic Solvents
  • Author : İlyasa Umur Ayaz
  • Publisher : Unknown Publisher
  • Release : 24 July 2021
GET THIS BOOKBiocatalytic Performance of Carbonic Anhydrase Immobilized Within Polyurethane Foam in Water-miscible Organic Solvents

The effects of water-miscible organic solvents such as acetonitrile and ethanol on the activity of free and immobilized bovine carbonic anhydrase (CA) were investigated. The CA was covalently immobilized within polyurethane (PU) foam by cross-linking. Although PU foam holds water almost 12 times of its weight, it was found that adsorption isotherm of moisture on PU foam was a Type III indicating that water and PU foam were non-interacting to each other. The activities for the free and immobilized CA were

The Carbonic Anhydrases

The Carbonic Anhydrases
  • Author : W.R. Chegwidden,N.D. Carter,Y.H. Edwards
  • Publisher : Birkhäuser
  • Release : 11 November 2013
GET THIS BOOKThe Carbonic Anhydrases

Carbonic anhydrase (CA) is a seemingly ubiquitous enzyme of profound physiological importance, which plays essential roles in respiration, acid-base homeostasis, bone resorption, calcification, photosynthesis, several biosynthetic pathways and a variety of processes involving ion, gas and fluid transfer. This enzyme, which is present in at least three gene families (a, ß, ?), has found favour as a model for the study of evolution of gene families and for site-directed mutagenesis in structure/function relationships, for protein folding and for transgenic and gene

Biocatalysis

Biocatalysis
  • Author : Gonzalo de Gonzalo,Pablo Domínguez de María
  • Publisher : Royal Society of Chemistry
  • Release : 02 November 2017
GET THIS BOOKBiocatalysis

Implementing biocatalytic strategies in an industrial setting is a challenging task, especially when commercial scale necessitates a balance between industrial need and economic viability. With invited contributions from a wide range of chemical and pharmaceutical companies, this book bridges the gap between academia and industry. Contributors discuss current processes, types of biocatalysts and improvements, industrial motivation and the key aspects needed for economic success. Focussing on industry related issues, this book will be a useful tool for future research by

Drug Design of Zinc-Enzyme Inhibitors

Drug Design of Zinc-Enzyme Inhibitors
  • Author : Claudiu T. Supuran,Jean-Yves Winum
  • Publisher : John Wiley & Sons
  • Release : 22 October 2009
GET THIS BOOKDrug Design of Zinc-Enzyme Inhibitors

Brings together functional and structural informationrelevant to the design of drugs targeting zinc enzymes The second most abundant transition element in living organisms, zinc spans all areas of metabolism, with zinc-containing proteins offering both established and potential drug targets. Drug Design of Zinc-Enzyme Inhibitors brings together functional and structural information relevant to these zinc-containing targets. With up-to-date overviews of the latest developments field, this unique and comprehensive text enables readers to understand zinc enzymes and evaluate them in a drug

Carbonic Anhydrase: Mechanism, Regulation, Links to Disease, and Industrial Applications

Carbonic Anhydrase: Mechanism, Regulation, Links to Disease, and Industrial Applications
  • Author : Susan C. Frost,Robert McKenna
  • Publisher : Springer Science & Business Media
  • Release : 22 October 2013
GET THIS BOOKCarbonic Anhydrase: Mechanism, Regulation, Links to Disease, and Industrial Applications

The study of carbonic anhydrase has spanned multiple generations of scientists. Carbonic anhydrase was first discovered in 1932 by Meldrum and Roughton. Inhibition by sulfanilamide was shown in 1940 by Mann and Keilin. Even Hans Krebs contributed to early studies with a paper in 1948 showing the relationship of 25 different sulfonamides to CA inhibition. It was he who pointed out the importance of both the charged and uncharged character of these compounds for physiological experiments. The field of study that focuses on carbonic