Carbonic Anhydrases as Biocatalysts

Carbonic anhydrases (CAs, EC 4.2.1.1) are ubiquitous metalloenzymes, present throughout most living organisms and encoded by five evolutionarily unrelated gene families. The Carbonic Anhydrases as Biocatalysts: From Theory to Medical and Industrial Applications presents information on the growing interest in the study of this enzyme family and their applications to both medicine and biotechnology. Offers comprehensive coverage of the carbonic anhydrases enzyme family and their properties as biocatalysts Includes current applications of carbonic anhydrases in biotechnology on the basis of their catalytic efficiency, including new technologies for CO2 capture processes Identifies new targets for drug design studies Provides a selectivity profile for the different carbonic anhydrases and their related biomedical applications

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  • Author : Claudiu T Supuran
  • Publisher : Elsevier
  • Pages : 398 pages
  • ISBN : 0444632638
  • Rating : 4/5 from 21 reviews
CLICK HERE TO GET THIS BOOKCarbonic Anhydrases as Biocatalysts

Carbonic Anhydrases as Biocatalysts

Carbonic Anhydrases as Biocatalysts
  • Author : Claudiu T Supuran,Giuseppina De Simone
  • Publisher : Elsevier
  • Release : 14 January 2015
GET THIS BOOKCarbonic Anhydrases as Biocatalysts

Carbonic anhydrases (CAs, EC 4.2.1.1) are ubiquitous metalloenzymes, present throughout most living organisms and encoded by five evolutionarily unrelated gene families. The Carbonic Anhydrases as Biocatalysts: From Theory to Medical and Industrial Applications presents information on the growing interest in the study of this enzyme family and their applications to both medicine and biotechnology. Offers comprehensive coverage of the carbonic anhydrases enzyme family and their properties as biocatalysts Includes current applications of carbonic anhydrases in biotechnology on the basis of their

Carbonic Anhydrases

Carbonic Anhydrases
  • Author : Claudiu T. Supuran,Alessio Nocentini
  • Publisher : Academic Press
  • Release : 17 July 2019
GET THIS BOOKCarbonic Anhydrases

Carbonic Anhydrases provides an interdisciplinary review of the burgeoning carbonic anhydrase (CA) research area, spanning from CAs classification (biochemical and structural features) to drug design and pharmacology of CA inhibitors and activators, finally touching on the biotechnological applications of these metalloenzymes. The book adopts a clear step-by-step approach and introduction to this intricate and highly interdisciplinary field. A diverse range of chapters from international experts speak to CA classification and distribution, the mechanisms of action and drug design of inhibitors

The Carbonic Anhydrases: Current and Emerging Therapeutic Targets

The Carbonic Anhydrases: Current and Emerging Therapeutic Targets
  • Author : W. Richard Chegwidden,Nicholas D. Carter
  • Publisher : Springer Nature
  • Release : 01 December 2021
GET THIS BOOKThe Carbonic Anhydrases: Current and Emerging Therapeutic Targets

This volume assembles and integrates the wealth of diverse information that is now accumulating in this burgeoning field. The existing and potential therapeutic applications of targeting CA cover a remarkably wide-range of diseases and disorders and have generated increasing and extensive interest in recent years. Its inter-disciplinary approach embraces both the most up-to-date therapeutic application of CA-targeting and the latest research data that will provide a platform for the development of novel applications. The interested audience comprises scientists and clinicians

Carbonic Anhydrases and Metabolism

Carbonic Anhydrases and Metabolism
  • Author : Claudiu T. Supuran
  • Publisher : MDPI
  • Release : 08 April 2019
GET THIS BOOKCarbonic Anhydrases and Metabolism

Carbonic anhydrases (CAs; EC 4.2.1.1) are metalloenzymes present in all kingdoms of life, as they equilibrate the reaction between three simple but essential chemical species: CO2, bicarbonate, and protons. Discovered more than 80 years ago, in 1933, these enzymes have been extensively investigated due to the biomedical application of their inhibitors, but also because they are an extraordinary example of convergent evolution, with seven genetically distinct CA families that evolved independently in Bacteria, Archaea, and Eukarya. CAs are also among the most efficient

Neutron Crystallography in Structural Biology

Neutron Crystallography in Structural Biology
  • Author : Anonim
  • Publisher : Academic Press
  • Release : 22 February 2020
GET THIS BOOKNeutron Crystallography in Structural Biology

Neutron Crystallography in Structural Biology, Volume 634, the latest volume in the Methods in Enzymology series, continues the legacy of this premier serial with quality chapters authored by leaders in the field. Chapters in this updated release include Fundamentals of neutron crystallography in structural biology, Large crystal growth for neutron protein crystallography, Prospects for membrane protein crystals in NMX, IMAGINE: The neutron protein crystallography beamline at the high flux isotope reactor, The macromolecular neutron diffractometer at the spallation neutron source, Current

Antiprotozoal Drug Development and Delivery

Antiprotozoal Drug Development and Delivery
  • Author : Alane Beatriz Vermelho,Claudiu T. Supuran
  • Publisher : Springer Nature
  • Release : 24 June 2022
GET THIS BOOKAntiprotozoal Drug Development and Delivery

This book reviews new promising drug targets for Neglected Tropical Diseases (NTDs), with a special focus on antiprotozoal drugs against trpyanosomatids Trypanosoma cruzi and Leishmania spp. The book offers a comprehensive overview of the most recent studied targets, and it outlines classical and new treatments and delivery strategies. Expert contributors describe new methods of analysis and bio-prospecting for new compounds, and provide a critical perspective of the translational process used in the research and development of new drug candidates. The

Carbon Capture and Storage in International Energy Policy and Law

Carbon Capture and Storage in International Energy Policy and Law
  • Author : Hirdan Katarina de Medeiros Costa,Carolina Arlota
  • Publisher : Elsevier
  • Release : 13 October 2021
GET THIS BOOKCarbon Capture and Storage in International Energy Policy and Law

Carbon Capture and Storage in International Energy Policy and Law identifies the main contemporary regulatory requirements, challenges and opportunities involving CCS from a comparative and interdisciplinary perspective. It draws on the scholarship of renowned researchers across the fields of international energy law and policy to address CCS regulation and its impact on climate change, sustainable development, and related consequences for energy transition. In this vein, the book aims to address issues related to energy, energy justice and climate changes (including

Carbon Utilization

Carbon Utilization
  • Author : Malti Goel,M. Sudhakar
  • Publisher : Springer
  • Release : 28 March 2017
GET THIS BOOKCarbon Utilization

This book provides in-depth information on topics relating to anthropogenic carbon dioxide utilization processes. Presenting a collection of state-of-the-art scientific reviews and research perspectives on carbon management strategies of relevance to the energy industry, it features contributions by leading scientists and technocrats across 19 chapters as an Indian contribution In the energy industry, new processes for carbon dioxide removal and recycling are developing quickly, and it is in this context that the book provides an opportunity to review the current status

Pharmaceutical Biocatalysis

Pharmaceutical Biocatalysis
  • Author : Peter Grunwald
  • Publisher : CRC Press
  • Release : 27 June 2019
GET THIS BOOKPharmaceutical Biocatalysis

This book provides an overview of the world market of therapeutic enzymes and enzyme inhibitors, rare diseases, orphan drugs, the costs of drug development and therapies, and enzymes in downstream processing of pharmaceuticals. It discusses carbonic anhydrase inhibitors and their multiple drug interactions, carboxylesterase inhibitors for pharmaceutical applications, employment of inhibitors for the treatment of neurodegenerative diseases, use of engineered proteins, bioactive peptides, and fibrinolytic enzymes for thrombolytic therapy, and enzymes important for the design and development of new drugs/

Climate Change and Green Chemistry of CO2 Sequestration

Climate Change and Green Chemistry of CO2 Sequestration
  • Author : Malti Goel,T. Satyanarayana,Maruthadu Sudhakar,D. P. Agrawal
  • Publisher : Springer Nature
  • Release : 10 May 2021
GET THIS BOOKClimate Change and Green Chemistry of CO2 Sequestration

The book comprises state-of-the-art scientific reviews on carbon management strategies in response to climate change. It provides in-depth information on topics relating to recent advances in carbon capture technology and its reuse in value added products. It features contributions of leading scientists and technocrats on topics including climate change and carbon sequestration, lowering carbon footprint CO2 capture, low carbon imperatives in oil industry, CO2 as refrigerant in cold-chain application, carbonic anhydrase-mediated carbon sequestration and utilization, chemical looping combustion with Indian

Carbonic Anhydrase: Mechanism, Regulation, Links to Disease, and Industrial Applications

Carbonic Anhydrase: Mechanism, Regulation, Links to Disease, and Industrial Applications
  • Author : Susan C. Frost,Robert McKenna
  • Publisher : Springer Science & Business Media
  • Release : 22 October 2013
GET THIS BOOKCarbonic Anhydrase: Mechanism, Regulation, Links to Disease, and Industrial Applications

The study of carbonic anhydrase has spanned multiple generations of scientists. Carbonic anhydrase was first discovered in 1932 by Meldrum and Roughton. Inhibition by sulfanilamide was shown in 1940 by Mann and Keilin. Even Hans Krebs contributed to early studies with a paper in 1948 showing the relationship of 25 different sulfonamides to CA inhibition. It was he who pointed out the importance of both the charged and uncharged character of these compounds for physiological experiments. The field of study that focuses on carbonic

Biocatalysis for Practitioners

Biocatalysis for Practitioners
  • Author : Gonzalo de Gonzalo,Iván Lavandera
  • Publisher : John Wiley & Sons
  • Release : 09 April 2021
GET THIS BOOKBiocatalysis for Practitioners

This reference book originates from the interdisciplinary research cooperation between academia and industry. In three distinct parts, latest results from basic research on stable enzymes are explained and brought into context with possible industrial applications. Downstream processing technology as well as biocatalytic and biotechnological production processes from global players display the enormous potential of biocatalysts. Application of "extreme" reaction conditions (i.e. unconventional, such as high temperature, pressure, and pH value) - biocatalysts are normally used within a well defined

Sustainable Bioconversion of Waste to Value Added Products

Sustainable Bioconversion of Waste to Value Added Products
  • Author : Inamuddin,Anish Khan
  • Publisher : Springer Nature
  • Release : 20 April 2021
GET THIS BOOKSustainable Bioconversion of Waste to Value Added Products

This edited book discusses various processes of feedstocks bioconversion such as bioconversion of food waste, human manure, industrial waste, beverage waste, kitchen waste, organic waste, fruit and vegetable, poultry waste, solid waste, agro-industrial waste, cow dung, steroid, lignocellulosic residue, biomass, natural gas etc. Nowadays, the industrial revolution and urbanization have made human life comfortable. However, this requires excess usage of natural resources starting from food and food products, to energy resources, materials as well as chemicals. The excess use of

An Economy Based on Carbon Dioxide and Water

An Economy Based on Carbon Dioxide and Water
  • Author : Michele Aresta,Iftekhar Karimi,Sibudjing Kawi
  • Publisher : Springer
  • Release : 01 July 2019
GET THIS BOOKAn Economy Based on Carbon Dioxide and Water

This book is devoted to CO2 capture and utilization (CCU) from a green, biotechnological and economic perspective, and presents the potential of, and the bottlenecks and breakthroughs in converting a stable molecule such as CO2 into specialty chemicals and materials or energy-rich compounds. The use of renewable energy (solar, wind, geothermal, hydro) and non-fossil hydrogen is a must for converting large volumes of CO2 into energy products, and as such, the authors explore and compare the availability of hydrogen from