Genome Editing in Cardiovascular and Metabolic Diseases

This book provides the latest research progress on genome editing in cardiovascular and metabolic diseases and includes bioinformatics research methodology of genome editing. Genome editing is a genetic engineering technique precisely modified specific target genes of organism genome, which has been applied to basic theoretical research and production applications from plants and animals to gene therapy of human beings. Cardiovascular and metabolic diseases have become major factors affecting human health worldwide. This book contains information about bioinformatics, genome editing in cardiovascular diseases, genome editing in metabolic diseases and therapeutic effects. It will be useful for biologist, cardiologist, cardiovascular surgeons, endocrinologist, internists, nurses, undergraduate and graduate students in medicine and cell biology and others interested in cardiovascular and metabolic medicine.

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  • Author : Junjie Xiao
  • Publisher : Springer
  • Pages : 0 pages
  • ISBN : 9789811956416
  • Rating : 4/5 from 21 reviews
CLICK HERE TO GET THIS BOOKGenome Editing in Cardiovascular and Metabolic Diseases

Genome Editing in Cardiovascular and Metabolic Diseases

Genome Editing in Cardiovascular and Metabolic Diseases
  • Author : Junjie Xiao
  • Publisher : Springer
  • Release : 30 October 2022
GET THIS BOOKGenome Editing in Cardiovascular and Metabolic Diseases

This book provides the latest research progress on genome editing in cardiovascular and metabolic diseases and includes bioinformatics research methodology of genome editing. Genome editing is a genetic engineering technique precisely modified specific target genes of organism genome, which has been applied to basic theoretical research and production applications from plants and animals to gene therapy of human beings. Cardiovascular and metabolic diseases have become major factors affecting human health worldwide. This book contains information about bioinformatics, genome editing in

Cardiovascular Diseases

Cardiovascular Diseases
  • Author : Nikolaos Papageorgiou
  • Publisher : Academic Press
  • Release : 05 August 2016
GET THIS BOOKCardiovascular Diseases

Cardiovascular Diseases: Genetic Susceptibility, Environmental Factors and Their Interaction covers the special heritability characteristics and identifying genetic and environmental contributions to cardiovascular health. This important reference provides an overview of the genetic basis of cardiovascular disease and its risk factors. Included are important topics, ranging from lifestyle choices, risk factors, and exposure, to pollutants and chemicals. Also covered are the influences of Mendelian traits and familial aggregation and the interactions and interrelationships between genetics and environmental factors which, when compared,

Translational Cardiometabolic Genomic Medicine

Translational Cardiometabolic Genomic Medicine
  • Author : Annabelle Rodriguez-Oquendo
  • Publisher : Academic Press
  • Release : 07 September 2015
GET THIS BOOKTranslational Cardiometabolic Genomic Medicine

Translational Cardiometabolic Genomic Medicine, edited by Dr. Annabelle Rodriguez-Oquendo, is an important resource to postgraduate (medical, dental and graduate) students, postdoctoral fellows, basic scientists, and physician scientists seeking to understand and expand their knowledge base in the field of genomic medicine as it is applied to cardiometabolic diseases. This handbook integrates cutting-edge experimental approaches such as chromatin immunoprecipitation paired end tagging (CHIA-PET), to population studies such as the Multi-Ethnic Study of Atherosclerosis. It encompasses a range of book chapters that

Genome Editing

Genome Editing
  • Author : Kiran Musunuru
  • Publisher : Academic Press
  • Release : 05 March 2021
GET THIS BOOKGenome Editing

Genome Editing: A Practical Guide to Research and Clinical Applications is geared towards investigators interested in learning how to use CRISPR-Cas9-based technologies, with a focus on cardiovascular research and clinical applications. Covering a range of topics from the basics of genome editing to design considerations, to assessments and applications, this reference allows readers to get started and establish a full workflow from the beginning of the project to its full completion. With worked examples drawn from real-life experiments, as

Cardiovascular Genomics

Cardiovascular Genomics
  • Author : Mohan K. Raizada,Julian F. R. Paton,Sergey Kasparov,Michael J. Katovich
  • Publisher : Springer Science & Business Media
  • Release : 06 January 2005
GET THIS BOOKCardiovascular Genomics

Recognized scientists and clinicians from around the world discuss the most recent molecular approaches to understanding the cardiovascular system in both health and disease. The authors focus on all components of the system, including blood vessels, heart, kidneys, and the brain, and cover disease states ranging from vascular and cardiac dysfunction to stroke and hypertension. The methods described for identifying the genes that cause susceptibility to cardiovascular diseases emphasize the possibility of discovering new drug targets. Authoritative and ground-breaking, Cardiovascular

Human Genome Editing

Human Genome Editing
  • Author : National Academies of Sciences, Engineering, and Medicine,National Academy of Medicine,National Academy of Sciences,Committee on Human Gene Editing: Scientific, Medical, and Ethical Considerations
  • Publisher : National Academies Press
  • Release : 13 August 2017
GET THIS BOOKHuman Genome Editing

Genome editing is a powerful new tool for making precise alterations to an organism's genetic material. Recent scientific advances have made genome editing more efficient, precise, and flexible than ever before. These advances have spurred an explosion of interest from around the globe in the possible ways in which genome editing can improve human health. The speed at which these technologies are being developed and applied has led many policymakers and stakeholders to express concern about whether appropriate systems are

Cardiac Gene Therapy

Cardiac Gene Therapy
  • Author : Kiyotake Ishikawa
  • Publisher : Humana Press
  • Release : 02 December 2016
GET THIS BOOKCardiac Gene Therapy

This detailed book provides methodological information on cardiac gene delivery, from classic to state-of-the-art technologies and techniques. Efficient, cardiac-specific, and safe vectors, as well as refined vector delivery methods, are key for successful cardiac gene transfer and eventually for improving patients’ outcomes. Newer vectors and more efficient vector delivery methods have the potential to dramatically improve gene transduction efficacy, while novel gene manipulation techniques enforce the therapeutic power and broaden disease targets. Written for the highly successful Methods in Molecular

Genome Plasticity in Health and Disease

Genome Plasticity in Health and Disease
  • Author : Anonim
  • Publisher : Academic Press
  • Release : 08 April 2020
GET THIS BOOKGenome Plasticity in Health and Disease

Genome Plasticity in Health and Disease provides a fully up-to-date overview on genome plasticity and its role in human physiology and disease. Following an introduction to the field, a diverse range of chapters cover genomic and epigenomic analysis and the use of model organisms and genomic databases in studies. Specific molecular and biochemical mechanisms of genome plasticity are examined, including somatic variants, De Novo variants, founder variations, isolated populations dynamics, copy-number variations, mobile elements, DNA methylation, histone modifications, transcription factors,

The Human Gene Editing Debate

The Human Gene Editing Debate
  • Author : John H. Evans
  • Publisher : Oxford University Press
  • Release : 19 August 2020
GET THIS BOOKThe Human Gene Editing Debate

In 2018 the first genetically modified babies were reportedly born in China, made possible by the invention of CRISPR technology in 2012. This controversial advancement overturned the pre-existing moral consensus, which had held for over fifty years before: while gene editing an adult person was morally acceptable, modifying babies, and thus subsequent generations, crossed a significant moral line. If this line is passed over, scientists will be left without an agreed-upon ethical limit. What do we do now? John H. Evans here

Human Flourishing in an Age of Gene Editing

Human Flourishing in an Age of Gene Editing
  • Author : Erik Parens,Josephine Johnston
  • Publisher : Oxford University Press
  • Release : 29 July 2019
GET THIS BOOKHuman Flourishing in an Age of Gene Editing

International uproar followed the recent announcement of the birth of twin girls whose genomes had been edited with a breakthrough DNA editing-technology. This technology, called clustered regularly interspaced short palindrome repeats or CRISPR-Cas9, can alter any DNA, including DNA in embryos, meaning that changes can be passed to the offspring of the person that embryo becomes. Should we use gene editing technologies to change ourselves, our children, and future generations to come? The potential uses of CRISPR-Cas9 and other gene

Genetics of Cardiovascular Disease

Genetics of Cardiovascular Disease
  • Author : Anonim
  • Publisher : Academic Press
  • Release : 18 April 2014
GET THIS BOOKGenetics of Cardiovascular Disease

This volume of the esteemed Progress in Molecular Biology and Translational Science series focuses on cutting-edge research related to the genetics of cardiovascular disease. Written by top experts in the field, this volume covers a range of topics, including: Genetic models of atherosclerosis MicroRNAs in cardiovascular disease The role of the transcription factor KLF2 in vascular development and disease Zebrafish as models of cardiovascular disease and hematopoietic development Progress in Molecular Biology and Translational Science provides a forum for discussion

Genomic and Precision Medicine

Genomic and Precision Medicine
  • Author : Geoffrey S. Ginsburg,Huntington F Willard,John Strickler,Matthew Stuart McKinney
  • Publisher : Academic Press
  • Release : 09 April 2022
GET THIS BOOKGenomic and Precision Medicine

Genomic and Precision Medicine: Oncology, Third Edition focuses on the applications of genome discovery as research points to personalized cancer therapies. Each chapter is organized to cover the application of genomics and personalized medicine tools and technologies to a) Risk Assessment and Susceptibility, b) Diagnosis and Prognosis, c) Pharmacogenomics and Precision Therapeutics, and d) Emerging and Future Opportunities in the field. Provides a comprehensive volume written and edited by oncology genomic specialists for oncology health providers Includes succinct commentary and

Genome Editing

Genome Editing
  • Author : Kursad Turksen
  • Publisher : Springer
  • Release : 09 August 2016
GET THIS BOOKGenome Editing

This timely volume explores the use of CRISPR-Cas9 for genome editing, presenting cutting-edge techniques and their applications in treatment of disease. The chapters describe latest methods such as use of targetable nucleases, investigation of the non-coding genome, mouse genome editing, increasing of knock-in efficiency in mouse zygotes, and generation of reporter stem cells; the text contextualizes these methods in treatment of cardiovascular disease, diabetes mellitus, retinitis pigmentosa, and others. The final chapters round out the book with a discussion of

Genetic Cardiomyopathies

Genetic Cardiomyopathies
  • Author : Gianfranco Sinagra,Fulvio Camerini,Luisa Mestroni
  • Publisher : Springer Science & Business Media
  • Release : 09 December 2012
GET THIS BOOKGenetic Cardiomyopathies

In the last decade, genetics has been emerging as a primary issue in the diagnosis and management of cardiomyopathies. This book is intended to be a state-of-the-art monograph on these diseases, describing their genetic causes, defining the molecular basis and presenting extensive descriptions of genotype–phenotype correlations. Other chapters are focused on the role of clinical observation, on ECG and echocardiography. With its highlight on the most recent discoveries in the field of molecular genetics as well as on the