Cell Polarity in Development and Disease

Cell Polarity in Development and Disease offers insights into the basic molecular mechanisms of common diseases that arise as a result of a loss of ordered organization and intrinsic polarity. Included are diseases affecting highly polarized epithelial tissues in the lung and kidney, as well as loss and gain of cell polarity in the onset and progression of cancer. This book provides a basic resource for understanding the biology of polarity, offering a starting point for those thinking of targeting cell polarity for translational medical research. Provides basic science understanding of cell polarity disease and development Covers diseases affecting polarized epithelial tissues in the lung and kidney, also covering the progression of cancer Includes historical context of cell polarity research for potential future breakthroughs

Produk Detail:

  • Author : Douglas W Houston
  • Publisher : Academic Press
  • Pages : 236 pages
  • ISBN : 0128125918
  • Rating : 4/5 from 21 reviews
CLICK HERE TO GET THIS BOOKCell Polarity in Development and Disease

Cell Polarity in Development and Disease

Cell Polarity in Development and Disease
  • Author : Douglas W Houston
  • Publisher : Academic Press
  • Release : 14 November 2017
GET THIS BOOKCell Polarity in Development and Disease

Cell Polarity in Development and Disease offers insights into the basic molecular mechanisms of common diseases that arise as a result of a loss of ordered organization and intrinsic polarity. Included are diseases affecting highly polarized epithelial tissues in the lung and kidney, as well as loss and gain of cell polarity in the onset and progression of cancer. This book provides a basic resource for understanding the biology of polarity, offering a starting point for those thinking of targeting

Cell Polarity 2

Cell Polarity 2
  • Author : Klaus Ebnet
  • Publisher : Springer
  • Release : 24 February 2015
GET THIS BOOKCell Polarity 2

This work provides a state-of-the art overview on the most relevant aspects of cell polarity. Volume 2 discusses the physiological and pathophysiological relevance of cell polarity. It especially focuses on pathophysiological conditions in which one or several aspects of cell polarity are impaired, and in which a loss of cell polarity possibly contributes to disease (e.g. epithelial-to-mesenchymal transition in cancer, role of polarity proteins in cancer). Both volumes are intended for professors, group leaders and researchers in cell biology as

Cellular Adhesion in Development and Disease

Cellular Adhesion in Development and Disease
  • Author : Anonim
  • Publisher : Academic Press
  • Release : 27 February 2015
GET THIS BOOKCellular Adhesion in Development and Disease

Cell adhesion is a fundamental determinant of embryonic development and organogenesis. Cellular Adhesion in Development and Disease, volume 112 in Current Topics in Developmental Biology, comprehensively surveys current developments in understanding how adhesion systems affect organismal development. Topics covered include nectins, nectin-like molecules, and afadin in development; cadherin adhesion, signaling, and morphogenesis; endothelial cell junctions; epidermal development and barrier formation; and more. This book surveys current understanding of how adhesion systems affect organismal development

Asymmetric Cell Division in Development, Differentiation and Cancer

Asymmetric Cell Division in Development, Differentiation and Cancer
  • Author : Jean-Pierre Tassan,Jacek Z. Kubiak
  • Publisher : Springer
  • Release : 12 April 2017
GET THIS BOOKAsymmetric Cell Division in Development, Differentiation and Cancer

This book provides readers with an overview of the frequent occurrence of asymmetric cell division. Employing a broad range of examples, it highlights how this mode of cell division constitutes the basis of multicellular organism development and how its misregulation can lead to cancer. To underline such developmental correlations, readers will for example gain insights into stem cell fate and tumor growth. In turn, subsequent chapters include descriptions of asymmetric cell division from unicellular organisms to humans in both physiological

GTPases Regulating Membrane Dynamics

GTPases Regulating Membrane Dynamics
  • Author : W. E. Balch,Channing J. Der,Alan Hall
  • Publisher : Gulf Professional Publishing
  • Release : 27 December 2005
GET THIS BOOKGTPases Regulating Membrane Dynamics

Provides a comprehensive set of articles describing the use and application of state-of-the-art methodologies to identify and characterize these GTPases and their expanding list of regulators and effectors. This work also includes methodologies focused on biochemical, molecular and advanced imaging techniques.

Planar Cell Polarity During Development

Planar Cell Polarity During Development
  • Author : Anonim
  • Publisher : Academic Press
  • Release : 31 December 2012
GET THIS BOOKPlanar Cell Polarity During Development

This new volume of Current Topics in Developmental Biology covers the area of Planar Cell Polarity with contributions from an international board of authors. The 12 chapters provide a comprehensive set of reviews covering such topics as PCP in Zebra fish, the role of Dishevelled in PCP regulation, and PCP in axon pathfinding. Covers the area of planar cell polarity International board of authors 12 chapters provide a comprehensive set of reviews covering such topics as planar cell polarity in Zebrafish, the

Role of Planar Cell Polarity Gene Vangl2 in Kidney Development and Disease

Role of Planar Cell Polarity Gene Vangl2 in Kidney Development and Disease
  • Author : Brittany Rocque
  • Publisher : Unknown Publisher
  • Release : 24 July 2021
GET THIS BOOKRole of Planar Cell Polarity Gene Vangl2 in Kidney Development and Disease

"The Planar Cell Polarity (PCP) signaling pathway is crucial for tissue morphogenesis. Vangl2 protein is central in the PCP pathway: its loss is embryonic lethal causing neural tube defects in mice and humans. In the kidney, PCP signaling is thought to be important for the organization of glomerular epithelial cells, podocytes, along the glomerular basement membrane. Podocyte cell protrusions, foot processes (FPs), are critical for kidney filtration functions; loss of FP architecture results in proteinuria and, in severe cases, focal

Cellular Networks in Development

Cellular Networks in Development
  • Author : Anonim
  • Publisher : Academic Press
  • Release : 01 April 2021
GET THIS BOOKCellular Networks in Development

Current Topics in Developmental Biology, Volume 143, the latest release in this acclaimed series, highlights new advances in the field, with this new volume presenting new sections on Building a ciliated epithelium: Transcriptional regulation and radial intercalation of multiciliated cells, Biomechanics of Amphibian Morphogenesis, Planar cell polarity during neural tube closure, Left-right asymmetry research in Xenopus: Questions solved and new frontiers, Xenopus neural crest and its relevance to human disease, Endoderm organogenesis, From egg to embryo in marsupial frogs, Evo-devo lessons

Adherens Junctions: from Molecular Mechanisms to Tissue Development and Disease

Adherens Junctions: from Molecular Mechanisms to Tissue Development and Disease
  • Author : Tony Harris
  • Publisher : Springer Science & Business Media
  • Release : 07 June 2012
GET THIS BOOKAdherens Junctions: from Molecular Mechanisms to Tissue Development and Disease

Cell–cell adhesion is fundamental for the development and homeostasis of animal tissues and organs. Adherens junctions (AJs) are the best understood cell-cell adhesion complexes. In this volume, a group of internationally recognized experts reviews AJ biology over a wide range of organization; from atoms to molecules, to protein complexes, molecular networks, cells, tissues, and overall animal development. AJs have also been an integral part of animal evolution, and play central roles in cancer development, pathogen infection and other diseases.

Neuronal Polarity: Establishment and Maintenance

Neuronal Polarity: Establishment and Maintenance
  • Author : Froylan Calderon de Anda,Annette Gaertner
  • Publisher : Frontiers Media SA
  • Release : 12 July 2018
GET THIS BOOKNeuronal Polarity: Establishment and Maintenance

The term polarity in a biological context is used to describe an asymmetry in morphology and distribution of molecules. In neurons, their complex shape with typically one axon and several dendrites reflects this asymmetry. Although neurons assume many different shapes and sizes they always maintain these two domains, which are essential for neuronal function. In the most simple view, neurons use their axon to transmit signals over long distances due to its capacity to extend to enormous lengths. Dendrites, on

Membrane Organization and Dynamics

Membrane Organization and Dynamics
  • Author : Amitabha Chattopadhyay
  • Publisher : Springer
  • Release : 06 December 2017
GET THIS BOOKMembrane Organization and Dynamics

This volume brings together information on membrane organization and dynamics from a variety of spectroscopic, microscopic and simulation approaches, spanning a broad range of time scales. The implication of such dynamic information on membrane function in health and disease is a topic of contemporary interest. The chapters cover various aspects of membrane lipid and protein dynamics, explored using a battery of experimental and theoretical approaches. The synthesis of information and knowledge gained by utilizing multiple approaches will provide the reader