Cell Polarity in Development and Disease

Cell Polarity in Development and Disease offers insights into the basic molecular mechanisms of common diseases that arise as a result of a loss of ordered organization and intrinsic polarity. Included are diseases affecting highly polarized epithelial tissues in the lung and kidney, as well as loss and gain of cell polarity in the onset and progression of cancer. This book provides a basic resource for understanding the biology of polarity, offering a starting point for those thinking of targeting cell polarity for translational medical research. Provides basic science understanding of cell polarity disease and development Covers diseases affecting polarized epithelial tissues in the lung and kidney, also covering the progression of cancer Includes historical context of cell polarity research for potential future breakthroughs

Produk Detail:

  • Author : Douglas W Houston
  • Publisher : Academic Press
  • Pages : 236 pages
  • ISBN : 0128125918
  • Rating : 4/5 from 21 reviews
CLICK HERE TO GET THIS BOOKCell Polarity in Development and Disease

Cell Polarity in Development and Disease

Cell Polarity in Development and Disease
  • Author : Douglas W Houston
  • Publisher : Academic Press
  • Release : 14 November 2017
GET THIS BOOKCell Polarity in Development and Disease

Cell Polarity in Development and Disease offers insights into the basic molecular mechanisms of common diseases that arise as a result of a loss of ordered organization and intrinsic polarity. Included are diseases affecting highly polarized epithelial tissues in the lung and kidney, as well as loss and gain of cell polarity in the onset and progression of cancer. This book provides a basic resource for understanding the biology of polarity, offering a starting point for those thinking of targeting

Methods in Kidney Cell Biology Part B

Methods in Kidney Cell Biology Part B
  • Author : Anonim
  • Publisher : Academic Press
  • Release : 01 September 2019
GET THIS BOOKMethods in Kidney Cell Biology Part B

Methods in Kidney Cell Biology, Part B, Volume 154 represents state-of-the-art techniques in renal research that are ideal for veterans, graduate students, postdoctoral fellows, clinical scientists and principal investigators. Topics in the new release include Single glomerular proteomics – a novel method in translational glomerular cell biology, Measurement of cytosolic and intraciliary calcium in live cells, Differentiation of human kidney organoids from pluripotent stem cells, Quantifying autophagic flux in kidney tissue using structured illumination microscopy, the Generation of primary cells from ADPKD

Planar Cell Polarity During Development

Planar Cell Polarity During Development
  • Author : Anonim
  • Publisher : Academic Press
  • Release : 31 December 2012
GET THIS BOOKPlanar Cell Polarity During Development

This new volume of Current Topics in Developmental Biology covers the area of Planar Cell Polarity with contributions from an international board of authors. The 12 chapters provide a comprehensive set of reviews covering such topics as PCP in Zebra fish, the role of Dishevelled in PCP regulation, and PCP in axon pathfinding. Covers the area of planar cell polarity International board of authors 12 chapters provide a comprehensive set of reviews covering such topics as planar cell polarity in Zebrafish, the

Protein Kinases in Development and Disease

Protein Kinases in Development and Disease
  • Author : Anonim
  • Publisher : Academic Press
  • Release : 22 February 2017
GET THIS BOOKProtein Kinases in Development and Disease

Protein Kinases in Development and Disease discusses and reviews important, but often neglected, kinases. A good representation of current model organisms from plants and C. elegans to mice are used as the basis to illustrate how we can use our understanding of normal development to learn about disease. Reviews kinases, the fundamental regulators of most biological processes that have key roles in the development of all organisms Includes a broad scope of topics that are addressed Allows researchers and newcomers

Asymmetric Cell Division in Development, Differentiation and Cancer

Asymmetric Cell Division in Development, Differentiation and Cancer
  • Author : Jean-Pierre Tassan,Jacek Z. Kubiak
  • Publisher : Springer
  • Release : 12 April 2017
GET THIS BOOKAsymmetric Cell Division in Development, Differentiation and Cancer

This book provides readers with an overview of the frequent occurrence of asymmetric cell division. Employing a broad range of examples, it highlights how this mode of cell division constitutes the basis of multicellular organism development and how its misregulation can lead to cancer. To underline such developmental correlations, readers will for example gain insights into stem cell fate and tumor growth. In turn, subsequent chapters include descriptions of asymmetric cell division from unicellular organisms to humans in both physiological

Lung Epithelial Biology in the Pathogenesis of Pulmonary Disease

Lung Epithelial Biology in the Pathogenesis of Pulmonary Disease
  • Author : Venkataramana K Sidhaye,Michael Koval
  • Publisher : Academic Press
  • Release : 09 March 2017
GET THIS BOOKLung Epithelial Biology in the Pathogenesis of Pulmonary Disease

Lung Epithelial Biology in the Pathogenesis of Pulmonary Disease provides a one-stop resource capturing developments in lung epithelial biology related to basic physiology, pathophysiology, and links to human disease. The book provides access to knowledge of molecular and cellular aspects of lung homeostasis and repair, including the molecular basis of lung epithelial intercellular communication and lung epithelial channels and transporters. Also included is coverage of lung epithelial biology as it relates to fluid balance, basic ion/fluid molecular processes, and

Cell Polarity 2

Cell Polarity 2
  • Author : Klaus Ebnet
  • Publisher : Springer
  • Release : 24 February 2015
GET THIS BOOKCell Polarity 2

This work provides a state-of-the art overview on the most relevant aspects of cell polarity. Volume 2 discusses the physiological and pathophysiological relevance of cell polarity. It especially focuses on pathophysiological conditions in which one or several aspects of cell polarity are impaired, and in which a loss of cell polarity possibly contributes to disease (e.g. epithelial-to-mesenchymal transition in cancer, role of polarity proteins in cancer). Both volumes are intended for professors, group leaders and researchers in cell biology as

GTPases Regulating Membrane Dynamics

GTPases Regulating Membrane Dynamics
  • Author : W. E. Balch,Channing J. Der,Alan Hall
  • Publisher : Gulf Professional Publishing
  • Release : 27 December 2005
GET THIS BOOKGTPases Regulating Membrane Dynamics

Provides a comprehensive set of articles describing the use and application of state-of-the-art methodologies to identify and characterize these GTPases and their expanding list of regulators and effectors. This work also includes methodologies focused on biochemical, molecular and advanced imaging techniques.

Membrane Organization and Dynamics

Membrane Organization and Dynamics
  • Author : Amitabha Chattopadhyay
  • Publisher : Springer
  • Release : 06 December 2017
GET THIS BOOKMembrane Organization and Dynamics

This volume brings together information on membrane organization and dynamics from a variety of spectroscopic, microscopic and simulation approaches, spanning a broad range of time scales. The implication of such dynamic information on membrane function in health and disease is a topic of contemporary interest. The chapters cover various aspects of membrane lipid and protein dynamics, explored using a battery of experimental and theoretical approaches. The synthesis of information and knowledge gained by utilizing multiple approaches will provide the reader

Ion Channels in Health and Disease

Ion Channels in Health and Disease
  • Author : Geoffrey S. Pitt
  • Publisher : Academic Press
  • Release : 04 October 2016
GET THIS BOOKIon Channels in Health and Disease

Ion Channels in Health and Disease provides key insight to allow researchers to generate discoveries across disease states. A single resource that integrates disparate areas of biology and disease ion channel biology, this publication includes cross-referencing for disease, channels, and tissues. Offers a broad view of research of interest to early and experienced researchers across biological and biomedical research. Provides an overview of fundamental concepts in ion channels research to link defects in human disease Written in an accessible manner,

Tight Junctions

Tight Junctions
  • Author : Marcelino Cereijido,James M. Anderson
  • Publisher : CRC Press
  • Release : 26 June 2001
GET THIS BOOKTight Junctions

As the first detailed overview of the subject, Tight Junctions brought together diverse perspectives from leading investigators to provide a multidisciplinary overview of the field. Since its publication in 1992, there has been an explosion of information about tight junctions, particularly in the area of molecular structure, cell and molecular biology, genetics and physiology. The field has advanced so fast and so far that it influences many areas of biology and now has practical implications for pharmacology of drug delivery and

Tau Biology

Tau Biology
  • Author : Akihiko Takashima,Benjamin Wolozin,Luc Buee
  • Publisher : Springer Nature
  • Release : 24 February 2020
GET THIS BOOKTau Biology

This book presents essential studies and cutting-edge research results on tau, which is attracting increasing interest as a target for the treatment of Alzheimer's disease. Tau is well known as a microtubule-associated protein that is predominantly localized in the axons of neurons. In various forms of brain disease, neuronal loss occurs, with deposition of hyperphosphorylated tau in the remaining neurons. Important questions remain regarding the way in which tau forms hyperphosphorylated and fibrillar deposits in neurons, and whether tau aggregation