Cell Polarity in Development and Disease

Cell Polarity in Development and Disease offers insights into the basic molecular mechanisms of common diseases that arise as a result of a loss of ordered organization and intrinsic polarity. Included are diseases affecting highly polarized epithelial tissues in the lung and kidney, as well as loss and gain of cell polarity in the onset and progression of cancer. This book provides a basic resource for understanding the biology of polarity, offering a starting point for those thinking of targeting cell polarity for translational medical research. Provides basic science understanding of cell polarity disease and development Covers diseases affecting polarized epithelial tissues in the lung and kidney, also covering the progression of cancer Includes historical context of cell polarity research for potential future breakthroughs

Produk Detail:

  • Author : Douglas W Houston
  • Publisher : Academic Press
  • Pages : 236 pages
  • ISBN : 0128125918
  • Rating : 4/5 from 21 reviews
CLICK HERE TO GET THIS BOOKCell Polarity in Development and Disease

Cell Polarity in Development and Disease

Cell Polarity in Development and Disease
  • Author : Douglas W Houston
  • Publisher : Academic Press
  • Release : 14 November 2017
GET THIS BOOKCell Polarity in Development and Disease

Cell Polarity in Development and Disease offers insights into the basic molecular mechanisms of common diseases that arise as a result of a loss of ordered organization and intrinsic polarity. Included are diseases affecting highly polarized epithelial tissues in the lung and kidney, as well as loss and gain of cell polarity in the onset and progression of cancer. This book provides a basic resource for understanding the biology of polarity, offering a starting point for those thinking of targeting

Cell Polarity 2

Cell Polarity 2
  • Author : Klaus Ebnet
  • Publisher : Springer
  • Release : 24 February 2015
GET THIS BOOKCell Polarity 2

This work provides a state-of-the art overview on the most relevant aspects of cell polarity. Volume 2 discusses the physiological and pathophysiological relevance of cell polarity. It especially focuses on pathophysiological conditions in which one or several aspects of cell polarity are impaired, and in which a loss of cell polarity possibly contributes to disease (e.g. epithelial-to-mesenchymal transition in cancer, role of polarity proteins in cancer). Both volumes are intended for professors, group leaders and researchers in cell biology as

Developmental and Stem Cell Biology in Health and Disease

Developmental and Stem Cell Biology in Health and Disease
  • Author : Ahmed El-Hashash
  • Publisher : Bentham Science Publishers
  • Release : 14 July 2016
GET THIS BOOKDevelopmental and Stem Cell Biology in Health and Disease

Research into stem cells started in the 1960s with experiments on spleen cultures. Evans and Kaufman made a breakthrough in mouse embryo culturing and embryonic stem cell extraction in 1981, followed by the work of Thomson in 1998 on the technique for extracting human embryonic stem cells. Since then, stem cell research has rapidly expanded as a therapeutic avenue for different diseases in humans. This book explains the basic developmental biology of stem cells including the development of stem cells during the

Planar Cell Polarity

Planar Cell Polarity
  • Author : Kursad Turksen
  • Publisher : Humana Press
  • Release : 30 April 2017
GET THIS BOOKPlanar Cell Polarity

Planar cell polarity (PCP), or the alignment of a collection of cells within a cell sheet, has proven, over time, to be vital in not only normal development but also in disease states. In Planar Cell Polarity: Methods and Protocols, expert researchers in the field present a number of detailed and well-designed protocols used successfully in their labs around the world. As a volume in the highly successful Methods in Molecular BiologyTM series, the chapters contain introductions to their respective

Cellular Networks in Development

Cellular Networks in Development
  • Author : Anonim
  • Publisher : Academic Press
  • Release : 02 April 2021
GET THIS BOOKCellular Networks in Development

Current Topics in Developmental Biology, Volume 143, the latest release in this acclaimed series, highlights new advances in the field, with this new volume presenting new sections on Building a ciliated epithelium: Transcriptional regulation and radial intercalation of multiciliated cells, Biomechanics of Amphibian Morphogenesis, Planar cell polarity during neural tube closure, Left-right asymmetry research in Xenopus: Questions solved and new frontiers, Xenopus neural crest and its relevance to human disease, Endoderm organogenesis, From egg to embryo in marsupial frogs, Evo-devo lessons

Extracellular Matrix Degradation

Extracellular Matrix Degradation
  • Author : William C. Parks,Robert Mecham
  • Publisher : Springer Science & Business Media
  • Release : 07 April 2011
GET THIS BOOKExtracellular Matrix Degradation

Regulated turnover of extracellular matrix (ECM) is an important component of tissue homeostasis. In recent years, the enzymes that participate in, and control ECM turnover have been the focus of research that touches on development, tissue remodeling, inflammation and disease. This volume in the Biology of Extracellular Matrix series provides a review of the known classes of proteases that degrade ECM both outside and inside the cell. The specific EMC proteases that are discussed include cathepsins, bacterial collagenases, matrix metalloproteinases,

Amphibian Models of Development and Disease

Amphibian Models of Development and Disease
  • Author : Anonim
  • Publisher : Academic Press
  • Release : 30 May 2021
GET THIS BOOKAmphibian Models of Development and Disease

Amphibian Models of Development and Disease, Volume 145 in the Current Topics in Developmental Biology series, highlights new advances in the field written by an international board of experts. New chapters in this release include Building a ciliated epithelium: Transcriptional regulation and radial intercalation of multiciliated cells, Biomechanics of Amphibian Morphogenesis, Planar cell polarity during neural tube closure, Xenopus neural crest and its relevance to human disease, Endoderm organogenesis, From egg to embryo in marsupial frogs, Evo-devo lessons from the analysis

Cellular Adhesion in Development and Disease

Cellular Adhesion in Development and Disease
  • Author : Anonim
  • Publisher : Academic Press
  • Release : 27 February 2015
GET THIS BOOKCellular Adhesion in Development and Disease

Cell adhesion is a fundamental determinant of embryonic development and organogenesis. Cellular Adhesion in Development and Disease, volume 112 in Current Topics in Developmental Biology, comprehensively surveys current developments in understanding how adhesion systems affect organismal development. Topics covered include nectins, nectin-like molecules, and afadin in development; cadherin adhesion, signaling, and morphogenesis; endothelial cell junctions; epidermal development and barrier formation; and more. This book surveys current understanding of how adhesion systems affect organismal development

Cell Polarity

Cell Polarity
  • Author : Keith E. Mostov
  • Publisher : Unknown Publisher
  • Release : 31 March 2017
GET THIS BOOKCell Polarity

Most animal cells are polarized, with structurally and functionally distinct regions. This polarization facilitates processes such as differentiation and morphogenesis, directional cell migration, nerve impulse transmission, and transport of molecules across tissues. The dysregulation of these processes can lead to developmental disorders and is a feature of many cancers. Written and edited by experts in the field, this collection from Cold Spring Harbor Perspectives in Biology reviews our understanding of the molecular mechanisms involved in establishing and maintaining cell polarity,

Tissue Remodeling and Epithelial Morphogenesis

Tissue Remodeling and Epithelial Morphogenesis
  • Author : Thomas Lecuit
  • Publisher : Academic Press
  • Release : 09 October 2009
GET THIS BOOKTissue Remodeling and Epithelial Morphogenesis

For more than 30 years, Current Topics in Developmental Biology has provided a forum for dissemination and discussion of new ideas and thought in developmental biology. Bringing together a series of articles on the structural, functional, and developmental characteristics of epithelials, this thematic volume represents a timely and valuable contribution to an exciting and multidisciplinary field of study. Because defects in epithelial function and growth control play a major role in human disease-cancerous tumors, spina bifida, cardiac malformations, for example-this volume

Cystogenesis

Cystogenesis
  • Author : Jong Hoon Park,Curie Ahn
  • Publisher : Springer
  • Release : 12 October 2016
GET THIS BOOKCystogenesis

Autosomal Dominant Polycystic Kidney Disease (ADPKD) is a highly prevalent hereditary renal disorder in which fluid-filled cysts are appeared in both kidneys. Main causative genes of ADPKD are PKD1 and PKD2, encoding for polycystin-1 (PC1) and polycystin-2 (PC2) respectively. Those proteins are localized on primary cilia and function as mechanosensor in response to the fluid flow, translating mechanistic stimuli into calcium signaling. With mutations either of PKD1 or PKD2, hyper-activated renal tubular epithelial cell proliferation is observed, followed by disrupted