Cell Surface GRP78 a New Paradigm in Signal Transduction Biology

Cell Surface GRP78, a New Paradigm in Signal Transduction Biology presents a new paradigm that has emerged in the past decade with the discovery that various intracellular proteins may acquire new functions as cell surface receptors. Two very prominent examples are ATP synthase and GRP78. While the role of cell surface ATP synthase has been reviewed in various books, this book directs its attention to the story of cell surface GRP78. Edited by the researcher who identified cell surface expression of the molecular chaperone GRP78 as a major factor in prostate cancer and other malignancies Presents an in-depth treatment of the biological underpinnings of GRP78 and its connection to disease Provides four-color illustrations that facilitate the narrative

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  • Author : Salvatore V. Pizzo
  • Publisher : Academic Press
  • Pages : 144 pages
  • ISBN : 0128123524
  • Rating : 4/5 from 21 reviews
CLICK HERE TO GET THIS BOOKCell Surface GRP78 a New Paradigm in Signal Transduction Biology

Cell Surface GRP78, a New Paradigm in Signal Transduction Biology

Cell Surface GRP78, a New Paradigm in Signal Transduction Biology
  • Author : Salvatore V. Pizzo
  • Publisher : Academic Press
  • Release : 20 March 2018
GET THIS BOOKCell Surface GRP78, a New Paradigm in Signal Transduction Biology

Cell Surface GRP78, a New Paradigm in Signal Transduction Biology presents a new paradigm that has emerged in the past decade with the discovery that various intracellular proteins may acquire new functions as cell surface receptors. Two very prominent examples are ATP synthase and GRP78. While the role of cell surface ATP synthase has been reviewed in various books, this book directs its attention to the story of cell surface GRP78. Edited by the researcher who identified cell surface expression

Mechanisms of Insulin Action

Mechanisms of Insulin Action
  • Author : Alan R. Saltiel,Jeffrey E. Pessin
  • Publisher : Springer Science & Business Media
  • Release : 05 October 2007
GET THIS BOOKMechanisms of Insulin Action

More than 18 million people in the United States have diabetes mellitus, and about 90% of these have the type 2 form of the disease. This book attempts to dissect the complexity of the molecular mechanisms of insulin action with a special emphasis on those features of the system that are subject to alteration in type 2 diabetes and other insulin resistant states. It explores insulin action at the most basic levels, through complex systems.

Tissue-Specific Vascular Endothelial Signals and Vector Targeting

Tissue-Specific Vascular Endothelial Signals and Vector Targeting
  • Author : Anonim
  • Publisher : Academic Press
  • Release : 27 September 2010
GET THIS BOOKTissue-Specific Vascular Endothelial Signals and Vector Targeting

The field of genetics is rapidly evolving, and new medical breakthroughs are occurring as a result of advances in knowledge gained from genetics research. This serial continually publishes important reviews of the broadest interest to geneticists and their colleagues in affiliated disciplines. Includes important reviews of the broadest interest to geneticists and their colleagues in affiliated disciplines, providing researchers an overview and synthesis of the latest findings in the area Presents up-to-date research from leaders in the field

Activins and Inhibins

Activins and Inhibins
  • Author : Gerald Litwack
  • Publisher : Academic Press
  • Release : 14 April 2021
GET THIS BOOKActivins and Inhibins

First published in 1943, Vitamins and Hormones is the longest-running serial published by Academic Press. The Editorial Board now reflects expertise in the field of hormone action, vitamin action, X-ray crystal structure, physiology, and enzyme mechanisms. Under the capable and qualified editorial leadership of Dr. Gerald Litwack, Vitamins and Hormones continues to publish cutting-edge reviews of interest to endocrinologists, biochemists, nutritionists, pharmacologists, cell biologists, and molecular biologists. Others interested in the structure and function of biologically active molecules like hormones and

Receptor Tyrosine Kinases: Structure, Functions and Role in Human Disease

Receptor Tyrosine Kinases: Structure, Functions and Role in Human Disease
  • Author : Deric L. Wheeler,Yosef Yarden
  • Publisher : Springer
  • Release : 26 November 2014
GET THIS BOOKReceptor Tyrosine Kinases: Structure, Functions and Role in Human Disease

Receptor Tyrosine Kinase: Structure, Functions and Role in Human Disease, for the first time, systematically covers the shared structural and functional features of the RTK family. Receptor Tyrosine Kinases (RTKs) play critical roles in embryogenesis, normal physiology and several diseases. And over the last decade they have become the Number 1 targets of cancer drugs. To be able to conduct fundamental research or to attempt to develop pharmacological agents able to enhance or intercept them, it is essential first to understand

Trafficking Inside Cells

Trafficking Inside Cells
  • Author : Nava Segev
  • Publisher : Springer Science & Business Media
  • Release : 30 May 2010
GET THIS BOOKTrafficking Inside Cells

This book covers the past, present and future of the intra-cellular trafficking field, which has made a quantum leap in the last few decades. It details how the field has developed and evolved as well as examines future directions.

The Biogenesis of Cellular Organelles

The Biogenesis of Cellular Organelles
  • Author : Chris Mullins
  • Publisher : Springer Science & Business Media
  • Release : 06 March 2007
GET THIS BOOKThe Biogenesis of Cellular Organelles

The Biogenesis of Cellular Organelles represents a comprehensive summary of recent advances in the study of the biogenesis and functional dynamics of the major organelles operating in the eukaryotic cell. This book begins by placing the study of organelle biogenesis in a historical perspective by describing past scientific strategies, theories, and findings and relating these foundations to current investigations. Reviews of protein and lipid mediators important for organelle biogenesis are then presented, and are followed by summaries focused on the

Calcium Signaling

Calcium Signaling
  • Author : Md. Shahidul Islam
  • Publisher : Springer Nature
  • Release : 23 October 2019
GET THIS BOOKCalcium Signaling

This volume contains a unique selection of chapters covering a wealth of contemporary topics in this ubiquitous and diverse system of cell signaling. It offers much more than the accessibility and authority of a primary text book, exploring topics ranging from the fundamental aspects of calcium signaling to its varied clinical implications. It presents comprehensive discussion of cutting-edge research alongside detailed analysis of critical issues, at the same time as setting out testable hypotheses that point the way to future

Hsp90 in Cancer: Beyond the Usual Suspects

Hsp90 in Cancer: Beyond the Usual Suspects
  • Author : Anonim
  • Publisher : Academic Press
  • Release : 23 February 2016
GET THIS BOOKHsp90 in Cancer: Beyond the Usual Suspects

Hsp90 in Cancer: Beyond the Usual Suspects, the latest volume in the Advances in Cancer Research series, focuses on the multifunctional molecular chaperone Hsp90 which regulates the post-translational stability and function of a broad repertoire of client proteins and discusses some of the lesser-known aspects of how Hsp90 and its related family members enable oncogenic transformation and malignant progression. Focuses on the multifunctional molecular chaperone Hsp90 which regulates the post-translational stability and function of a broad repertoire of client proteins

Systems Biology in Cancer Research and Drug Discovery

Systems Biology in Cancer Research and Drug Discovery
  • Author : Asfar S Azmi
  • Publisher : Springer Science & Business Media
  • Release : 29 September 2012
GET THIS BOOKSystems Biology in Cancer Research and Drug Discovery

Systems Biology in Cancer Research and Drug Discovery provides a unique collection of chapters, by world-class researchers, describing the use of integrated systems biology and network modeling in the cancer field where traditional tools have failed to deliver expected promise. This book touches four applications/aspects of systems biology (i) in understanding aberrant signaling in cancer (ii) in identifying biomarkers and prognostic markers especially focused on angiogenesis pathways (iii) in unwinding microRNAs complexity and (iv) in anticancer drug discovery and

Biological, Diagnostic and Therapeutic Advances in Alzheimer's Disease

Biological, Diagnostic and Therapeutic Advances in Alzheimer's Disease
  • Author : Ghulam Md Ashraf,Athanasios Alexiou
  • Publisher : Springer Nature
  • Release : 16 December 2019
GET THIS BOOKBiological, Diagnostic and Therapeutic Advances in Alzheimer's Disease

This book discusses the latest research into the highly prevalent neurodevelopmental disease most commonly associated with aging: Alzheimer’s disease (AD). Even after years of research, Alzheimer’s disease is still far from being cured. It presents a range of common symptoms in the form of behavioral and cognitive impairments. This book describes the symptoms and the biology behind them. The contents covers latest findings on the genetics involved and various factors and pathways influencing disease development. It also covers

Biochemistry and Molecular Biology Compendium

Biochemistry and Molecular Biology Compendium
  • Author : Roger L. Lundblad
  • Publisher : CRC Press
  • Release : 11 November 2019
GET THIS BOOKBiochemistry and Molecular Biology Compendium

This book is an accessible resource offering practical information not found in more database-oriented resources. The first chapter lists acronyms with definitions, and a glossary of terms and subjects used in biochemistry, molecular biology, biotechnology, proteomics, genomics, and systems biology. There follows chapters on chemicals employed in biochemistry and molecular biology, complete with properties and structure drawings. Researchers will find this book to be a valuable tool that will save them time, as well as provide essential links to the

Current Research Topics in Plant Virology

Current Research Topics in Plant Virology
  • Author : Aiming Wang,Xueping Zhou
  • Publisher : Springer
  • Release : 07 July 2016
GET THIS BOOKCurrent Research Topics in Plant Virology

Topics covered in this book include RNA silencing and its suppression in plant virus infection, virus replication mechanisms, the association of cellular membranes with virus replication and movement, plant genetic resistance to viruses, viral cell-to-cell spread, long distance movement in plants, virus induced ER stress, virus diversity and evolution, virus-vector interactions, cross protection, geminiviruses, negative strand RNA viruses, viroids, and the diagnosis of plant viral diseases using next generation sequencing. This book was anticipated to help plant pathologists, scholars, professors,

Cellular and Molecular Biology of Metals

Cellular and Molecular Biology of Metals
  • Author : Rudolfs K. Zalups,D. James Koropatnick
  • Publisher : CRC Press
  • Release : 21 May 2010
GET THIS BOOKCellular and Molecular Biology of Metals

With chapter contributions from more than 30 metal biology experts, Cellular and Molecular Biology of Metals explains the role of key divalent metal ions involved in the molecular and cellular biology of various target cell populations. Although it primarily focuses on homeostatic metals, such as nickel, zinc, and chromium, the text also discusses a few environmentally pertinent, toxic divalent cations, including mercury, cadmium, and arsenic. This authoritative resource reviews the physiological mechanisms underlying the handling of essential and toxic metal ions,

Handbook of Cell Signaling

Handbook of Cell Signaling
  • Author : Ralph A. Bradshaw,Edward A. Dennis
  • Publisher : Academic Press
  • Release : 03 November 2009
GET THIS BOOKHandbook of Cell Signaling

Handbook of Cell Signaling, Three-Volume Set, 2e, is a comprehensive work covering all aspects of intracellular signal processing, including extra/intracellular membrane receptors, signal transduction, gene expression/translation, and cellular/organotypic signal responses. The second edition is an up-to-date, expanded reference with each section edited by a recognized expert in the field. Tabular and well illustrated, the Handbook will serve as an in-depth reference for this complex and evolving field. Handbook of Cell Signaling, 2/e will appeal to a broad,