Chimeric Antigen Receptor T Cell Therapies for Cancer E Book

From patient referral to post-therapy management, Chimeric Antigen Receptor (CAR) T-Cell Therapies for Cancer: A Practical Guide presents a comprehensive view of CAR modified T-cells in a concise and practical format. Providing authoritative guidance on the implementation and management of CAR T-cell therapy from Drs. Daniel W. Lee and Nirali N. Shah, this clinical resource keeps you up to date on the latest developments in this rapidly evolving area. Covers all clinical aspects, including patient referral, toxicities management, comorbidities, bridging therapy, post-CAR monitoring, and multidisciplinary approaches to supportive care. Includes key topics on associated toxicities such as predictive biomarkers, infections, and multidisciplinary approaches to supportive care. Presents current knowledge on FDA approved CAR T-cell products as well as developments on the horizon. Editors and authors represent leading investigators in academia and worldwide pioneers of CAR therapy.

Produk Detail:

  • Author : Daniel W. Lee
  • Publisher : Elsevier Health Sciences
  • Pages : 244 pages
  • ISBN : 0323755976
  • Rating : 4/5 from 21 reviews
CLICK HERE TO GET THIS BOOKChimeric Antigen Receptor T Cell Therapies for Cancer E Book

Chimeric Antigen Receptor T-Cell Therapies for Cancer E-Book

Chimeric Antigen Receptor T-Cell Therapies for Cancer E-Book
  • Author : Daniel W. Lee,Nirali N. Shah
  • Publisher : Elsevier Health Sciences
  • Release : 30 November 2019
GET THIS BOOKChimeric Antigen Receptor T-Cell Therapies for Cancer E-Book

From patient referral to post-therapy management, Chimeric Antigen Receptor (CAR) T-Cell Therapies for Cancer: A Practical Guide presents a comprehensive view of CAR modified T-cells in a concise and practical format. Providing authoritative guidance on the implementation and management of CAR T-cell therapy from Drs. Daniel W. Lee and Nirali N. Shah, this clinical resource keeps you up to date on the latest developments in this rapidly evolving area. Covers all clinical aspects, including patient referral, toxicities management, comorbidities, bridging

Chimeric Antigen Receptor T-Cell Therapies for Cancer

Chimeric Antigen Receptor T-Cell Therapies for Cancer
  • Author : Daniel W. Lee,Nirali N. Shah, M.D.
  • Publisher : Elsevier
  • Release : 02 December 2019
GET THIS BOOKChimeric Antigen Receptor T-Cell Therapies for Cancer

From patient referral to post-therapy management, Chimeric Antigen Receptor (CAR) T-Cell Therapies for Cancer: A Practical Guide presents a comprehensive view of CAR modified T-cells in a concise and practical format. Providing authoritative guidance on the implementation and management of CAR T-cell therapy from Drs. Daniel W. Lee and Nirali N. Shah, this clinical resource keeps you up to date on the latest developments in this rapidly evolving area. Covers all clinical aspects, including patient referral, toxicities management, comorbidities, bridging

Basics of Chimeric Antigen Receptor (CAR) Immunotherapy

Basics of Chimeric Antigen Receptor (CAR) Immunotherapy
  • Author : Mumtaz Y. Balkhi
  • Publisher : Academic Press
  • Release : 31 July 2019
GET THIS BOOKBasics of Chimeric Antigen Receptor (CAR) Immunotherapy

Basics of Chimeric Antigen Receptor (CAR) Immunotherapy presents the latest on how T cell adoptive immunotherapy has progressed in its ultimate goal of curing metastatic malignant cancers. Recent clinical data obtained with checkpoint receptor blockade inhibitors and chimeric antigen receptor (CAR) therapy has been especially promising, thus generating renewed hope that we may be on the verge of finally curing cancer. Over the years, huge progress has been made in controlling several stage IV metastasized cancers through the clinical application

Chimeric Antigen Receptor T‐Cell Therapy for the Community Oncologist

Chimeric Antigen Receptor T‐Cell Therapy for the Community Oncologist
  • Author : Anonim
  • Publisher : Unknown Publisher
  • Release : 06 May 2021
GET THIS BOOKChimeric Antigen Receptor T‐Cell Therapy for the Community Oncologist

Abstract : The field of cancer immunotherapy has rapidly progressed in the past decade as several therapeutic modalities have entered into the clinic. One such immunotherapy that has shown promise in the treatment of cancer is the use of chimeric antigen receptor (CAR)‐modified T lymphocytes. CARs are engineered receptors constructed from antigen recognition regions of antibodies fused to T‐cell signaling and costimulatory domains that can be used to reprogram a patient's T cells to specifically target tumor cells. CAR

Chimeric Antigen Receptor T Cells

Chimeric Antigen Receptor T Cells
  • Author : Kamilla Swiech,Kelen Cristina Ribeiro Malmegrim,Virgínia Picanço-Castro
  • Publisher : Humana
  • Release : 24 November 2020
GET THIS BOOKChimeric Antigen Receptor T Cells

This volume provides comprehensive methods from expert scientists working in the Chimeric Antigen Receptor T Cell (CAR-T Cell) field. Chapters guide readers through the state-of-art of CAR-T cell technology, CAR design and vector production, CAR-T cell generation and manufacturing, CAR-T cell characterization, and quality control. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and

Immunotherapy for Pediatric Malignancies

Immunotherapy for Pediatric Malignancies
  • Author : Juliet C. Gray,Aurélien Marabelle
  • Publisher : Springer
  • Release : 21 November 2017
GET THIS BOOKImmunotherapy for Pediatric Malignancies

This book provides a comprehensive overview of current immunotherapy strategies, and how these may be applicable to childhood cancers. The first part of the book reviews how the immune system recognizes cancer, and the various escape mechanisms allowing tumour growth. The importance of the tumor microenvironment and the challenges this may present to achieving effective immunotherapy are discussed. Monoclonal antibodies, cellular, cytokine and vaccine therapies are all comprehensively reviewed, with particular focus on their potential application to pediatric cancers. Practical

Developments in T Cell Based Cancer Immunotherapies

Developments in T Cell Based Cancer Immunotherapies
  • Author : Paolo A. Ascierto,David F. Stroncek,Ena Wang
  • Publisher : Humana Press
  • Release : 26 November 2015
GET THIS BOOKDevelopments in T Cell Based Cancer Immunotherapies

This volume illustrates the salient aspects of cancer biology relevant to the successful implementation of immunotherapy. Topics include enhancement of antigen-specific immune responses by anti-cancer vaccines, modulation of the function of T cells within the tumor microenvironment, and the effects of genetic, epigenetic, developmental, and environmental determinants on T cell function. Other topics covered include the ex vivo expansion of T or other immune cells and their genetic modification or reprogramming to increase their ability to survive and expand when

Oncoimmunology

Oncoimmunology
  • Author : Laurence Zitvogel,Guido Kroemer
  • Publisher : Springer
  • Release : 13 December 2017
GET THIS BOOKOncoimmunology

In this book, leading experts in cancer immunotherapy join forces to provide a comprehensive guide that sets out the main principles of oncoimmunology and examines the latest advances and their implications for clinical practice, focusing in particular on drugs with FDA/EMA approvals and breakthrough status. The aim is to deliver a landmark educational tool that will serve as the definitive reference for MD and PhD students while also meeting the needs of established researchers and healthcare professionals. Immunotherapy-based approaches

CAR-T Cell Therapies for Non-Hematopoietic Malignancies: Taking Off The Training Wheels

CAR-T Cell Therapies for Non-Hematopoietic Malignancies: Taking Off The Training Wheels
  • Author : Avery Dexter Posey, Jr.,John - Maher,Marcela V. Maus
  • Publisher : Frontiers Media SA
  • Release : 24 April 2020
GET THIS BOOKCAR-T Cell Therapies for Non-Hematopoietic Malignancies: Taking Off The Training Wheels

Chimeric antigen receptor (CAR) T cell therapies for leukemia (e.g. tisagenlecleucel) and lymphoma (e.g. axicabtagene ciloleucel) have recently received regulatory approval in the United States. Phase I/II trials have demonstrated complete remission of refractory or relapsed tumors in 50% - 94% patients. However, the clinical successes of engineered T cells for the treatment of solid malignancies have thus far been few and far between. Furthermore, several instances of severe and lethal toxicities have arisen due to on-target, off-tumor recognition

Cell and Gene Therapies

Cell and Gene Therapies
  • Author : Miguel-Angel Perales,Syed A. Abutalib,Catherine Bollard
  • Publisher : Springer
  • Release : 27 November 2018
GET THIS BOOKCell and Gene Therapies

In this book, experts in the field express their well-reasoned opinions on a range of complex, clinically relevant issues across the full spectrum of cell and gene therapies with the aim of providing trainee and practicing hematologists, including hematopoietic transplant physicians, with information that is relevant to clinical practice and ongoing research. Each chapter focuses on a particular topic, and the concise text is supported by numerous working tables, algorithms, and figures. Whenever appropriate, guidance is provided regarding the availability

Immunotherapy

Immunotherapy
  • Author : Krassimir Metodiev
  • Publisher : BoD – Books on Demand
  • Release : 26 April 2017
GET THIS BOOKImmunotherapy

This is another attempt of InTechOpen to continue the dissemination of international knowledge and experience in the field of immunology. The present book includes a number of modern concepts of specialists and experts in the field of immunotherapy, covering the major topics and analyzing the history, current stage, and future ideas of application of modern immunomodulation. It is always a benefit, but also a compliment, to gather a team of internationally distinguished authors and to motivate them to reveal their

Cancer and Aging

Cancer and Aging
  • Author : M. Extermann
  • Publisher : Karger Medical and Scientific Publishers
  • Release : 18 January 2013
GET THIS BOOKCancer and Aging

Cancer is clearly an age-related disease. Recent research in both aging and cancer has demonstrated the complex interaction between the two phenomena. This affects a wide spectrum of research and practice, anywhere from basic research to health care organization. Core examples of these close associations are addressed in this book. Starting with basic research, the first chapters cover cancer development, mTOR inhibition, senescent cells altering the tumor microenvironment, and immune senescence affecting cancer vaccine response. Taking into account the multidisciplinarity

Immune Regulation

Immune Regulation
  • Author : Marc Feldmann,N. A. Mitchison
  • Publisher : Springer Science & Business Media
  • Release : 06 December 2012
GET THIS BOOKImmune Regulation

Leukocyte culture conferences have a long pedigree. This volume records some of the scientific highlights of the 16th such annual con ference, and is a witness to the continuing evolution and popularity of leukocyte culture and of immunology. There is strong evidence of the widening horizons of immunology, both technically, with the obviously major impact of molecular biology into our understanding of cellular processes, and also conceptually. Traditionally, the 'proceedings' of these conferences have been published. But have the books

Cancer Cell Signaling

Cancer Cell Signaling
  • Author : Martha Robles-Flores
  • Publisher : Humana Press
  • Release : 17 September 2016
GET THIS BOOKCancer Cell Signaling

Cancer Cell Signaling: Methods and Protocols, Second Edition brings together the most recent advances in cancer cell signaling knowledge along with recent progress in the development of novel strategies and experimental cell models to study human cancer. Opening with a section on targeting cancer cell metabolism as an anticancer strategy, this detailed volume continues with parts describing protocols to study epigenetic control of cancer, protocols to study cancer metastasis, as well as two new techniques for cancer study. Written for

Second Generation Cell and Gene-Based Therapies

Second Generation Cell and Gene-Based Therapies
  • Author : Alain Vertes,Nathan J. Dowden,Devyn Smith,Nasib Qureshi
  • Publisher : Academic Press
  • Release : 07 February 2020
GET THIS BOOKSecond Generation Cell and Gene-Based Therapies

Second Generation Cell and Gene-Based Therapies: Biological Advances, Clinical Outcomes, and Strategies for Capitalisation serves as the only volume to the market to bridge basic science, clinical therapy, technology development, and business in the field of cellular therapy/cytotherapy. After more than two decades of painstaking fundamental research, the concept of therapeutic cells (stem cells, genes, etc.), beyond the concept of vaccines, is reaching clinical trial, with mounting confidence in the safety and efficacy of these products. Nonetheless, numerous incremental