Clinical Perspectives and Targeted Therapies in Apoptosis

Clinical Perspectives and Targeted Therapies in Apoptosis: Drug Discovery, Drug Delivery, and Disease Prevention provides comprehensive coverage, from basic cell biology, to modern assessment techniques for apoptosis in all major disease areas. Chapters provide an introduction to the fundamentals of cell biology, biochemical mechanisms, and the pathophysiological consequences of apoptosis. In addition, the book covers the tools and techniques used to quantify apoptosis and the significance of apoptosis in drug discovery, drug delivery, and its applications in disease prevention. Finally, the book provides a comprehensive compilation of the apoptosis targeting drugs that recently underwent clinical trials. This combination of fundamentals, along with applications in drug discovery, drug delivery, and clinical research make this book a useful resource for those in both academia and industry who are engaged in pharmaceutical, biomedical and biotechnology research. Offers standard and innovative therapeutic approaches to modulate apoptosis in clinical interventions, such as cardiovascular diseases, immune disorders, cancer chemotherapy and neurological ailments Covers cutting-edge laboratory techniques and traditional protocols to determine apoptosis, both in vitro and in vivo Examines clinical study reports of new drug moieties that are explored for various pathological conditions associated with apoptosis

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  • Author : Rupinder K. Sodhi
  • Publisher : Academic Press
  • Pages : 432 pages
  • ISBN : 0128157631
  • Rating : 4/5 from 21 reviews
CLICK HERE TO GET THIS BOOKClinical Perspectives and Targeted Therapies in Apoptosis

Clinical Perspectives and Targeted Therapies in Apoptosis

Clinical Perspectives and Targeted Therapies in Apoptosis
  • Author : Rupinder K. Sodhi,Jitender Madan
  • Publisher : Academic Press
  • Release : 30 October 2020
GET THIS BOOKClinical Perspectives and Targeted Therapies in Apoptosis

Clinical Perspectives and Targeted Therapies in Apoptosis: Drug Discovery, Drug Delivery, and Disease Prevention provides comprehensive coverage, from basic cell biology, to modern assessment techniques for apoptosis in all major disease areas. Chapters provide an introduction to the fundamentals of cell biology, biochemical mechanisms, and the pathophysiological consequences of apoptosis. In addition, the book covers the tools and techniques used to quantify apoptosis and the significance of apoptosis in drug discovery, drug delivery, and its applications in disease prevention. Finally,

Cell Death

Cell Death
  • Author : Tobias Ntuli
  • Publisher : BoD – Books on Demand
  • Release : 16 December 2015
GET THIS BOOKCell Death

This book is a collection of selected and relevant research, concerning the developments within the Cell Death field of study. Each contribution comes as a separate chapter complete in itself but directly related to the books topics and objectives. The target audience comprises scholars and specialists in the field.

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  • Author : Stephen Neidle
  • Publisher : Elsevier
  • Release : 28 April 2011
GET THIS BOOKCancer Drug Design and Discovery

The ultimate source of information on the design of new anticancer agents, emphasizing small molecules, this newest work covers recent notable successes resulting from the human genome and cancer genomics projects. These advances have provided information on targets involved in specific cancers that are leading to effective medicines for at least some of the common solid tumors. Unique sections explain the basic underlying principles of cancer drug development and provide a practical introduction to modern methods of drug design. Appealing

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  • Publisher : BoD – Books on Demand
  • Release : 25 April 2018
GET THIS BOOKDendrimers

Dendrimers are defined as nanoscale macromolecules having a particular architecture consisting of treelike arms or branches. They are characterized by special properties that make them promising candidates in medicine, biology, materials science, synthetic organic chemistry, biotechnology, environmental engineering, optics, electronics, catalysis, electrochemistry, photochemistry, and sensors and even for production of cosmetics and personal care products. The dendrimers research field is growing day by day, and scientists are exploring new synthesis and functionalization methods in order to improve and to determine

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  • Publisher : BoD – Books on Demand
  • Release : 29 August 2018
GET THIS BOOKCurrent Understanding of Apoptosis

Apoptosis is an essential biochemical process in cell turnover, development, and chemical-induced cell death. Current knowledge and ongoing research of apoptosis highlight our understanding in designing the therapeutic approaches for several diseases. This book covers four main sections: "Apoptosis and Necrosis," "Apoptosis Inducers," "Proteasome and Signaling Pathways in Apoptosis," and "Radiation-Based Apoptosis." The first section implicitly describes the differences between apoptosis and necrosis processes. The following section elaborates the small molecule-induced apoptosis. Then, the third section deals with proteasome and

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  • Author : Alexandru Mihai Grumezescu
  • Publisher : William Andrew
  • Release : 21 May 2018
GET THIS BOOKDrug Targeting and Stimuli Sensitive Drug Delivery Systems

Drug Targeting and Stimuli Sensitive Drug Delivery Systems covers recent advances in the area of stimuli sensitive drug delivery systems, providing an up-to-date overview of the physical, chemical, biological and multistimuli-responsive nanosystems. In addition, the book presents an analysis of clinical status for different types of nanoplatforms. Written by an internationally diverse group of researchers, it is an important reference resource for both biomaterials scientists and those working in the pharmaceutical industry who are looking to help create more effective

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  • Author : Dan Simionescu,Agneta Simionescu
  • Publisher : BoD – Books on Demand
  • Release : 05 April 2017
GET THIS BOOKPhysiologic and Pathologic Angiogenesis

The purpose of this book is to highlight novel advances in the field and to incentivize scientists from a variety of fields to pursue angiogenesis as a research avenue. Blood vessel formation and maturation to capillaries, arteries, or veins is a fascinating area which can appeal to multiple scientists, students, and professors alike. Angiogenesis is relevant to medicine, engineering, pharmacology, and pathology and to the many patients suffering from blood vessel diseases and cancer, among others. We are hoping that

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  • Author : Ahmed Lasfar
  • Publisher : BoD – Books on Demand
  • Release : 21 November 2018
GET THIS BOOKLiver Cancer

This book offers remarkable coverage of liver cancer from etiology to prevention and treatment. It provides an updated and new vision of this major cancer that continues to affect hundreds of thousands of people and remains one of the leading causes of cancer deaths around the world. To ensure the high quality of this book, important insights are included and rigorously discussed in a simple and authentic way. The book includes detailed and updated descriptions of the main causes of

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  • Author : Stevo Najman
  • Publisher : BoD – Books on Demand
  • Release : 20 January 2016
GET THIS BOOKCell Biology

Cell biology is a multidisciplinary scientific field that its modern expansion in new knowledge and applications owes to important support of new technologies with the rapid development, such as ICTs. By integrating knowledge from nano-, molecular, micro-, and macroareas, it represents a strong foundation for almost all biological sciences and disciplines, as well as for biomedical research and application. This book is a compilation of inspiring reviews/original studies, which are divided into sections: New Methods in Cell Biology, Molecular

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  • Author : Costin Teodor Streba,Cristin Constantin Vere,Ion Rogoveanu
  • Publisher : BoD – Books on Demand
  • Release : 28 November 2018
GET THIS BOOKHepatocellular Carcinoma

Hepatocellular carcinoma (HCC) currently ranks as the third most common cause of death. As the primary malignancy of the liver is directly related to an underlying liver condition, its incidence and profile are expected to change soon. While effective prevention programs and antiviral therapies for hepatitis B and C will lower the incidence of HCC, emerging socioeconomic issues will deliver new at-risk populations. Moreover, diagnostic techniques and protocols have undergone significant advancements. Reliance on contrast enhanced ultrasound has been re-evaluated,

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  • Author : Raymond J. Fonseca
  • Publisher : Saunders
  • Release : 06 March 2021
GET THIS BOOKOral and Maxillofacial Surgery

This comprehensive resource provides in-depth information to help you perfect your oral and maxillofacial surgical technique and provide state-of-the-art care for your patients. The full scope of the field is represented with up-to-date, evidence-based coverage of every surgical procedure performed today. Volume I: Anesthesia and Pain Control, Dentoalveolar Surgery, Practice Management, Implant Surgery brings you authoritative coverage of office-based procedures, including extractions, implants, and biopsies. [editor].

Nanoarchitectonics for Smart Delivery and Drug Targeting

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  • Author : Alina Maria Holban,Alexandru Mihai Grumezescu
  • Publisher : William Andrew
  • Release : 12 July 2016
GET THIS BOOKNanoarchitectonics for Smart Delivery and Drug Targeting

Nanoarchitectonics for Smart Delivery and Drug Targeting is one of the first books on the market to exclusively focus on the topic of nanoarchitectonics, a rapidly developing area of nanotechnology which allows scientists to arrange nanoscale structural units, typically a group of atoms or molecules, in an intended configuration. This book assesses novel applications of nanomaterials in the areas of smart delivery and drug targeting using nanoarchitectonics and discusses the advantages and disadvantages of each application. Provides a scholarly introduction

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  • Author : Apostolia-Maria Tsimberidou,Razelle Kurzrock,Kenneth C. Anderson
  • Publisher : John Wiley & Sons
  • Release : 08 October 2015
GET THIS BOOKTargeted Therapy in Translational Cancer Research

Targeted Therapy in Translational Cancer Research for the Translational Oncology series provides a comprehensive overview of recent developments in our understanding of tumor biology, elucidates the roles of targets and pathways involved in carcinogenesis, and describes current state-of-the-art anticancer therapy, as well as the most promising areas of translational research and targeted therapy. Introduces cutting-edge ‘bench to bedside and back’ breakthroughs which have transformed the diagnosis, prognosis, and treatment of cancer Covers basic principles of targeted therapy, including immunotherapy and

Apoptosis and Cancer Chemotherapy

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  • Author : John A. Hickman,Caroline Dive
  • Publisher : Springer Science & Business Media
  • Release : 08 April 1999
GET THIS BOOKApoptosis and Cancer Chemotherapy

The past few years have witnessed an astonishing international effort that established the role of some 20 new molecules in apoptosis and added activation or suppression of apoptosis to the accepted biological functions of a great many others already familiar in cancer biology. Some of these molecules are receptors, transducing cytokine-mediated signals; others appear to intensify or diminish the risk that a compro mised cell will fire its apoptosis effector mechanism. All are of interest as potential targets for tumor therapy,