Fundamentals of Clinical Trials

This classic reference, now updated with the newest applications and results, addresses the fundamentals of such trials based on sound scientific methodology, statistical principles, and years of accumulated experience by the three authors.

Produk Detail:

  • Author : Lawrence M. Friedman
  • Publisher : Springer Science & Business Media
  • Pages : 361 pages
  • ISBN : 9780387985862
  • Rating : 4.5/5 from 2 reviews
CLICK HERE TO GET THIS BOOKFundamentals of Clinical Trials

Fundamentals of Clinical Trials

Fundamentals of Clinical Trials
  • Author : Lawrence M. Friedman,Curt Furberg,David L. DeMets
  • Publisher : Springer Science & Business Media
  • Release : 02 March 1998
GET THIS BOOKFundamentals of Clinical Trials

This classic reference, now updated with the newest applications and results, addresses the fundamentals of such trials based on sound scientific methodology, statistical principles, and years of accumulated experience by the three authors.

Clinical Trials

Clinical Trials
  • Author : Tom Brody
  • Publisher : Academic Press
  • Release : 25 October 2011
GET THIS BOOKClinical Trials

Clinical Trials: Study Design, Endpoints and Biomarkers, Drug Safety, and FDA and ICH Guidelines is a practical guidebook for those engaged in clinical trial design. This book details the organizations and content of clinical trials, including trial design, safety, endpoints, subgroups, HRQoL, consent forms and package inserts. It provides extensive information on both US and international regulatory guidelines and features concrete examples of study design from the medical literature. This book is intended to orient those new to clinical trial

Introduction to Randomized Controlled Clinical Trials, Second Edition

Introduction to Randomized Controlled Clinical Trials, Second Edition
  • Author : John N.S. Matthews
  • Publisher : CRC Press
  • Release : 26 June 2006
GET THIS BOOKIntroduction to Randomized Controlled Clinical Trials, Second Edition

Evidence from randomized controlled clinical trials is widely accepted as the only sound basis for assessing the efficacy of new medical treatments. Statistical methods play a key role in all stages of these trials, including their justification, design, and analysis. This second edition of Introduction to Randomized Controlled Clinical Trials provides a concise presentation of the principles applied in this area. It details the concepts behind randomization and methods for designing and analyzing trials and also includes information on meta-analysis

Statistics Applied to Clinical Trials

Statistics Applied to Clinical Trials
  • Author : Ton J. Cleophas,A.H. Zwinderman
  • Publisher : Springer Science & Business Media
  • Release : 11 November 2013
GET THIS BOOKStatistics Applied to Clinical Trials

In 1948 the first randomized controlled trial was published by the English Medical Research Council in the British Medical Journal. Until then, observations had been uncontrolled. Initially, trials frequently did not confirm the hypotheses to be tested. This phenomenon was attributed to low sensitivity due to small samples, as well as inappropriate hypotheses based on biased prior trials. Additional flaws were recognized and, subsequently, were better accounted for: carryover effects due to insufficient washout from previous treatments, time effects due to

Cancer Clinical Trials

Cancer Clinical Trials
  • Author : Stephen L. George,Xiaofei Wang,Herbert Pang
  • Publisher : CRC Press
  • Release : 19 August 2016
GET THIS BOOKCancer Clinical Trials

Cancer Clinical Trials: Current and Controversial Issues in Design and Analysis provides statisticians with an understanding of the critical challenges currently encountered in oncology trials. Well-known statisticians from academic institutions, regulatory and government agencies (such as the U.S. FDA and National Cancer Institute), and the pharmaceutical industry share their extensive experiences in cancer clinical trials and present examples taken from actual trials. The book covers topics that are often perplexing and sometimes controversial in cancer clinical trials. Most of

Noninferiority Testing in Clinical Trials

Noninferiority Testing in Clinical Trials
  • Author : Tie-Hua Ng
  • Publisher : CRC Press
  • Release : 01 December 2014
GET THIS BOOKNoninferiority Testing in Clinical Trials

Take Your NI Trial to the Next Level Reflecting the vast research on noninferiority (NI) designs from the past 15 years, Noninferiority Testing in Clinical Trials: Issues and Challenges explains how to choose the NI margin as a small fraction of the therapeutic effect of the active control in a clinical trial. Requiring no prior knowledge of NI testing, the book is easily accessible to both statisticians and nonstatisticians involved in drug development. With over 20 years of experience in this area,

Clinical Trials

Clinical Trials
  • Author : Duolao Wang,Ameet Bakhai
  • Publisher : Remedica
  • Release : 02 March 2021
GET THIS BOOKClinical Trials

This book aims to demystify clinical trials. It is divided into five sections: fundamentals of trial design, alternative trial designs, basics of statistical analysis, special trial issues in data analysis, and reporting of trials. Using simple language the book explains with illustrations of numerous trial examples, the conceptual and methodological issues that occur at all stages of clinical trial covering trial design, conduct, analysis and reporting. The book is an educational and approachable reference in a difficult area of medicine

Clinical Trials in Osteoporosis

Clinical Trials in Osteoporosis
  • Author : Derek Pearson
  • Publisher : Springer Science & Business Media
  • Release : 02 March 2021
GET THIS BOOKClinical Trials in Osteoporosis

Clinical Trials in Osteoporosisis a practical handbook on clinical trials in the growing field of osteoporosis. Topics covered include study design, technical issues, data collection, quality assurance, data analysis and presentation. It aims to take the user through the process step-by-step from start to finish, also providing a background on regulatory guidelines, ethical implications, endpoints, current therapies and the ideal drug to use. There are no other books at present that specifically address the issue of clinical trials in osteoporosis.

Introduction to Statistical Methods for Clinical Trials

Introduction to Statistical Methods for Clinical Trials
  • Author : Thomas D. Cook,David L DeMets
  • Publisher : CRC Press
  • Release : 19 November 2007
GET THIS BOOKIntroduction to Statistical Methods for Clinical Trials

Clinical trials have become essential research tools for evaluating the benefits and risks of new interventions for the treatment and prevention of diseases, from cardiovascular disease to cancer to AIDS. Based on the authors’ collective experiences in this field, Introduction to Statistical Methods for Clinical Trials presents various statistical topics relevant to the design, monitoring, and analysis of a clinical trial. After reviewing the history, ethics, protocol, and regulatory issues of clinical trials, the book provides guidelines for formulating primary

Textbook of Clinical Trials in Oncology

Textbook of Clinical Trials in Oncology
  • Author : Susan Halabi,Stefan Michiels
  • Publisher : CRC Press
  • Release : 24 April 2019
GET THIS BOOKTextbook of Clinical Trials in Oncology

There is an increasing need for educational resources for statisticians and investigators. Reflecting this, the goal of this book is to provide readers with a sound foundation in the statistical design, conduct, and analysis of clinical trials. Furthermore, it is intended as a guide for statisticians and investigators with minimal clinical trial experience who are interested in pursuing a career in this area. The advancement in genetic and molecular technologies have revolutionized drug development. In recent years, clinical trials have