Fundamentals of Clinical Trials

This classic reference, now updated with the newest applications and results, addresses the fundamentals of such trials based on sound scientific methodology, statistical principles, and years of accumulated experience by the three authors.

Produk Detail:

  • Author : Lawrence M. Friedman
  • Publisher : Springer Science & Business Media
  • Pages : 361 pages
  • ISBN : 9780387985862
  • Rating : 4.5/5 from 2 reviews
CLICK HERE TO GET THIS BOOKFundamentals of Clinical Trials

Fundamentals of Clinical Trials

Fundamentals of Clinical Trials
  • Author : Lawrence M. Friedman,Curt Furberg,David L. DeMets
  • Publisher : Springer Science & Business Media
  • Release : 18 September 1998
GET THIS BOOKFundamentals of Clinical Trials

This classic reference, now updated with the newest applications and results, addresses the fundamentals of such trials based on sound scientific methodology, statistical principles, and years of accumulated experience by the three authors.

Clinical Trials

Clinical Trials
  • Author : Tom Brody
  • Publisher : Academic Press
  • Release : 19 February 2016
GET THIS BOOKClinical Trials

Clinical Trials, Second Edition, offers those engaged in clinical trial design a valuable and practical guide. This book takes an integrated approach to incorporate biomedical science, laboratory data of human study, endpoint specification, legal and regulatory aspects and much more with the fundamentals of clinical trial design. It provides an overview of the design options along with the specific details of trial design and offers guidance on how to make appropriate choices. Full of numerous examples and now containing actual

Global Clinical Trials

Global Clinical Trials
  • Author : Richard Chin,Menghis Bairu
  • Publisher : Academic Press
  • Release : 06 May 2011
GET THIS BOOKGlobal Clinical Trials

This book will explore the great opportunities and challenges which exist in conducting clinical trials in developing countries. By exploring the various regulations specific to the major players and providing insight into the logistical challenges including language barriers, this book provides a working tool for clinical researchers and administrators to navigate the intricacies of clinical trials in developing countries. Important topics such as ethical issues will be handled very carefully to highlight the significant differences of conducting this work in

Pragmatic Randomized Clinical Trials

Pragmatic Randomized Clinical Trials
  • Author : Cynthia J. Girman,Mary E. Ritchey
  • Publisher : Academic Press
  • Release : 23 April 2021
GET THIS BOOKPragmatic Randomized Clinical Trials

Pragmatic Randomized Clinical Trials Using Primary Data Collection and Electronic Health Records addresses the practical aspects and challenges of the design, implementation, and dissemination of pragmatic randomized trials, also sometimes referred to as practical or hybrid randomized trials. While less restrictive and more generalizable than traditional randomized controlled trials, such trials have specific challenges which are addressed in this book. The book contains chapters encompassing common designs along with advantages and limitations of such designs, analytic aspects in planning trials

A Comprehensive and Practical Guide to Clinical Trials

A Comprehensive and Practical Guide to Clinical Trials
  • Author : Delva Shamley,Brenda Wright
  • Publisher : Academic Press
  • Release : 07 June 2017
GET THIS BOOKA Comprehensive and Practical Guide to Clinical Trials

A Comprehensive and Practical Guide to Clinical Trials provides an overview of the entire process of clinical research in one thorough and easy-to-read handbook that offers those involved in clinical research a clear understanding of how the components of a study are related. It focuses on the practical aspects of the preparation and execution of a clinical trial and offers tools and resources to help the entire team understand how their responsibilities tie together with the tasks and duties of

Economic Evaluation in Clinical Trials

Economic Evaluation in Clinical Trials
  • Author : Henry A. Glick,Jalpa A. Doshi,Seema S. Sonnad,Daniel Polsky
  • Publisher : Oxford University Press, USA
  • Release : 02 October 2014
GET THIS BOOKEconomic Evaluation in Clinical Trials

It is becoming increasingly important to examine the relationship between the outcomes of a clinical trial and the costs of the medical therapy under study. The results of such analysis can affect reimbursement decisions for new medical technologies, drugs, devices or diagnostics. It can aid companies seeking to make claims about the cost-effectiveness of their product, as well as allowing early consideration of the economic value of therapies which may be important to improving initial adoption decisions. It is also

Bayesian Approaches to Clinical Trials and Health-Care Evaluation

Bayesian Approaches to Clinical Trials and Health-Care Evaluation
  • Author : David J. Spiegelhalter,Keith R. Abrams,Jonathan P. Myles
  • Publisher : John Wiley & Sons
  • Release : 16 January 2004
GET THIS BOOKBayesian Approaches to Clinical Trials and Health-Care Evaluation

READ ALL ABOUT IT! David Spiegelhalter has recently joined the ranks of Isaac Newton, Charles Darwin and Stephen Hawking by becoming a fellow of the Royal Society. Originating from the Medical Research Council’s biostatistics unit, David has played a leading role in the Bristol heart surgery and Harold Shipman inquiries. Order a copy of this author’s comprehensive text TODAY! The Bayesian approach involves synthesising data and judgement in order to reach conclusions about unknown quantities and make predictions.

Clinical Trials with Missing Data

Clinical Trials with Missing Data
  • Author : Michael O'Kelly,Bohdana Ratitch
  • Publisher : John Wiley & Sons
  • Release : 07 April 2014
GET THIS BOOKClinical Trials with Missing Data

This book provides practical guidance for statisticians, clinicians, and researchers involved in clinical trials in the biopharmaceutical industry, medical and public health organisations. Academics and students needing an introduction to handling missing data will also find this book invaluable. The authors describe how missing data can affect the outcome and credibility of a clinical trial, show by examples how a clinical team can work to prevent missing data, and present the reader with approaches to address missing data effectively. The

Clinical Trials

Clinical Trials
  • Author : Steven Piantadosi
  • Publisher : John Wiley & Sons
  • Release : 29 May 2013
GET THIS BOOKClinical Trials

Learn rigorous statistical methods to ensure valid clinicaltrials This Second Edition of the critically hailed Clinical Trials buildson the text's reputation as a straightforward and authoritativepresentation of statistical methods for clinical trials. Readersare introduced to the fundamentals of design for various types ofclinical trials and then skillfully guided through the completeprocess of planning the experiment, assembling a study cohort,assessing data, and reporting results. Throughout the process, theauthor alerts readers to problems that may arise during the courseof the trial

Clinical Trials

Clinical Trials
  • Author : Stuart J. Pocock
  • Publisher : John Wiley & Sons
  • Release : 17 July 2013
GET THIS BOOKClinical Trials

This comprehensive, unified text on the principles and practice of clinical trials presents a detailed account of how to conduct the trials. It describes the design, analysis, and interpretation of clinical trials in a non-technical manner and provides a general perspective on their historical development, current status, and future strategy. Features examples derived from the author's personal experience.

Bayesian Adaptive Methods for Clinical Trials

Bayesian Adaptive Methods for Clinical Trials
  • Author : Scott M. Berry,Bradley P. Carlin,J. Jack Lee,Peter Muller
  • Publisher : CRC Press
  • Release : 19 July 2010
GET THIS BOOKBayesian Adaptive Methods for Clinical Trials

Already popular in the analysis of medical device trials, adaptive Bayesian designs are increasingly being used in drug development for a wide variety of diseases and conditions, from Alzheimer’s disease and multiple sclerosis to obesity, diabetes, hepatitis C, and HIV. Written by leading pioneers of Bayesian clinical trial designs, Bayesian Adaptive Methods for Clinical Trials explores the growing role of Bayesian thinking in the rapidly changing world of clinical trial analysis. The book first summarizes the current state of

Designs for Clinical Trials

Designs for Clinical Trials
  • Author : David Harrington
  • Publisher : Springer Science & Business Media
  • Release : 09 October 2011
GET THIS BOOKDesigns for Clinical Trials

This book will examine current issues and controversies in the design of clinical trials, including topics in adaptive and sequential designs, the design of correlative genomic studies, the design of studies in which missing data is anticipated. Each chapter will be written by an expert conducting research in the topic of that chapter. As a collection, the chapters would be intended to serve as a guidance for statisticians designing trials.

Introduction to Randomized Controlled Clinical Trials

Introduction to Randomized Controlled Clinical Trials
  • Author : John N.S. Matthews
  • Publisher : CRC Press
  • Release : 26 June 2006
GET THIS BOOKIntroduction to Randomized Controlled Clinical Trials

Evidence from randomized controlled clinical trials is widely accepted as the only sound basis for assessing the efficacy of new medical treatments. Statistical methods play a key role in all stages of these trials, including their justification, design, and analysis. This second edition of Introduction to Randomized Controlled Clinical Trials prov

Anticancer Drug Development Guide

Anticancer Drug Development Guide
  • Author : Beverly A. Teicher
  • Publisher : Springer Science & Business Media
  • Release : 11 November 2013
GET THIS BOOKAnticancer Drug Development Guide

Experienced cancer researchers from pharmaceutical companies, government laboratories, and academia comprehensively review and describe the arduous process of cancer drug discovery and approval. They focus on using preclinical in vivo and in vitro methods to identify molecules of interest, detailing the targets and criteria for success in each type of testing and defining the value of the information obtained from the various tests. They also define each stage of clinical testing, explain the criteria for success, and outline the requirements

The Design and Analysis of Sequential Clinical Trials

The Design and Analysis of Sequential Clinical Trials
  • Author : John Whitehead
  • Publisher : John Wiley & Sons
  • Release : 04 August 1997
GET THIS BOOKThe Design and Analysis of Sequential Clinical Trials

This book details all aspects of sequential clinical trials from preliminary planning, through the monitoring of the trial, to the final analysis of the results. Emphasis is placed on the triangular test and other procedures based on straight line stopping boundaries. These methods allow for frequent or occasional interim analyses and permit the analysis of a wide variety of patient responses. Alternative procedures are also covered in detail, and these include -spending function methods, repeated confidence intervals and Bayesian approaches