Computational Non coding RNA Biology

Computational Non-coding RNA Biology is a resource for the computation of non-coding RNAs. The book covers computational methods for the identification and quantification of non-coding RNAs, including miRNAs, tasiRNAs, phasiRNAs, lariat originated circRNAs and back-spliced circRNAs, the identification of miRNA/siRNA targets, and the identification of mutations and editing sites in miRNAs. The book introduces basic ideas of computational methods, along with their detailed computational steps, a critical component in the development of high throughput sequencing technologies for identifying different classes of non-coding RNAs and predicting the possible functions of these molecules. Finding, quantifying, and visualizing non-coding RNAs from high throughput sequencing datasets at high volume is complex. Therefore, it is usually possible for biologists to complete all of the necessary steps for analysis. Presents a comprehensive resource of computational methods for the identification and quantification of non-coding RNAs Introduces 23 practical computational pipelines for various topics of non-coding RNAs Provides a guide to assist biologists and other researchers dealing with complex datasets Introduces basic computational methods and provides guidelines for their replication by researchers Offers a solution to researchers approaching large and complex sequencing datasets

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  • Author : Yun Zheng
  • Publisher : Academic Press
  • Pages : 320 pages
  • ISBN : 0128143665
  • Rating : 4/5 from 21 reviews
CLICK HERE TO GET THIS BOOKComputational Non coding RNA Biology

Computational Non-coding RNA Biology

Computational Non-coding RNA Biology
  • Author : Yun Zheng
  • Publisher : Academic Press
  • Release : 14 September 2018
GET THIS BOOKComputational Non-coding RNA Biology

Computational Non-coding RNA Biology is a resource for the computation of non-coding RNAs. The book covers computational methods for the identification and quantification of non-coding RNAs, including miRNAs, tasiRNAs, phasiRNAs, lariat originated circRNAs and back-spliced circRNAs, the identification of miRNA/siRNA targets, and the identification of mutations and editing sites in miRNAs. The book introduces basic ideas of computational methods, along with their detailed computational steps, a critical component in the development of high throughput sequencing technologies for identifying different

Computational Biology of Non-Coding RNA

Computational Biology of Non-Coding RNA
  • Author : Xin Lai,Shailendra K. Gupta,Julio Vera
  • Publisher : Humana Press
  • Release : 04 February 2019
GET THIS BOOKComputational Biology of Non-Coding RNA

This volume details a collection of state-of-art methods including identification of novel ncRNAs and their targets, functional annotation and disease association in different biological contexts. Chapters guide readers through an overview of disease-specific ncRNAs, computational methods and workflows for ncRNA discovery, annotation based on high-throughput sequencing data, bioinformatics tools and databases for ncRNA analyses, network-based methods, and kinetic modelling of ncRNA-mediated gene regulation. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective

AGO-Driven Non-Coding RNAs

AGO-Driven Non-Coding RNAs
  • Author : Bibekanand Mallick
  • Publisher : Academic Press
  • Release : 20 January 2019
GET THIS BOOKAGO-Driven Non-Coding RNAs

The ‘RNA world’ hypothesis that proposed RNA molecules as the first form of genetic material was put forwarded in the late 1980s but got impetus only recently when high-throughput sequencing technologies began unearthing new types of non-coding RNA (ncRNA) transcripts in higher eukaryotes. Till then, research on ncRNAs were primarily confined to transfer RNAs and, ribosomal RNAs, which act as the messengers of the protein synthesis and allow translation of genetic information encoded by DNA into proteins. In recent years,

Long Non Coding RNA Biology

Long Non Coding RNA Biology
  • Author : M.R.S. Rao
  • Publisher : Springer
  • Release : 16 August 2017
GET THIS BOOKLong Non Coding RNA Biology

This contributed volume offers a comprehensive and detailed overview of the various aspects of long non-coding RNAs and discusses their emerging significance. Written by leading experts in the field, it motivates young researchers around the globe, and offers graduate and postgraduate students fascinating insights into genes and their regulation in eukaryotes and higher organisms.

Cancer and Noncoding RNAs

Cancer and Noncoding RNAs
  • Author : Jayprokas Chakrabarti,Sanga Mitra
  • Publisher : Academic Press
  • Release : 13 October 2017
GET THIS BOOKCancer and Noncoding RNAs

Cancer and Noncoding RNAs offers an in-depth exploration of noncoding RNAs and their role in epigenetic regulation of complex human disease, most notably cancer. In addition to examining microRNAs, this volume provides a unique evaluation of more recently profiled noncoding RNAs now implicated in carcinogenesis, including lncRNAs, piRNAs, circRNAs, and tRNAs, identifying differences in function between these noncoding RNAs and how they interact with the rest of the epigenome. A broad range of chapters from experts in the field detail

Non-Coding RNAs

Non-Coding RNAs
  • Author : Jan Barciszewski
  • Publisher : Springer Science & Business Media
  • Release : 31 August 2003
GET THIS BOOKNon-Coding RNAs

General inspection of a role performed in the cell by RNAs allows us to distinguish three major groups of transcripts: I. protein-coding mRNAs, II. non-coding housekeeping and III. regulatory RNAs. The housekeeping RNAs include RNA classes that are generally, constitutively expressed and whose presence is required for normal function and viability of the cells. On the other hand, a group of regulatory RNAs includes RNA species that are expressed at certain stages of organism development or cell differentiation or as

Long Non-Coding RNAs

Long Non-Coding RNAs
  • Author : Yi Feng,Lin Zhang
  • Publisher : Humana Press
  • Release : 01 January 2016
GET THIS BOOKLong Non-Coding RNAs

This volume assembles a broad spectrum of methods used in long non-coding RNAs (lncRNA) research, ranging from computational annotation of lncRNA genes to molecular and cellular analyses of the function of individual lncRNA. Long Non-Coding RNAs: Methods and Protocols also discusses methods used to study circular RNAs and RNA splicing, as well as influential findings on lncRNA in human diseases. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of

Computational Biology and Bioinformatics

Computational Biology and Bioinformatics
  • Author : Ka-Chun Wong
  • Publisher : CRC Press
  • Release : 27 April 2016
GET THIS BOOKComputational Biology and Bioinformatics

The advances in biotechnology such as the next generation sequencing technologies are occurring at breathtaking speed. Advances and breakthroughs give competitive advantages to those who are prepared. However, the driving force behind the positive competition is not only limited to the technological advancement, but also to the companion data analytical skills and computational methods which are collectively called computational biology and bioinformatics. Without them, the biotechnology-output data by itself is raw and perhaps meaningless. To raise such awareness, we have

Non-coding RNAs in Cardiovascular Diseases

Non-coding RNAs in Cardiovascular Diseases
  • Author : Junjie Xiao
  • Publisher : Springer Nature
  • Release : 07 May 2021
GET THIS BOOKNon-coding RNAs in Cardiovascular Diseases

This book presents the latest research on non-coding RNAs in cardiovascular disease, a major cause of death worldwide. Non-coding RNAs play a significant role in development, proliferation, differentiation and apoptosis. Since altered non-coding RNA expression is often associated with various diseases, their potential use in diagnostics, prognostics and therapeutics is an important current area of study. The book consists of six parts: 1) An overview of non-coding RNAs and cardiovascular system, 2) Bioinformatics and interactions, 3) Non-coding RNA regulation in cardiovascular system, 4) Non-coding

Non Coding RNAs in Plants

Non Coding RNAs in Plants
  • Author : Volker A. Erdmann,Jan Barciszewski
  • Publisher : Springer Science & Business Media
  • Release : 20 July 2011
GET THIS BOOKNon Coding RNAs in Plants

In the most recent years, each of the RNA silencing pathways of plants have appeared to generate ncRNAs with dedicated functions, specialized biological activities and specific functional scopes. RNA silencing plays a crucial role in coordinating the expression, stability, protection and inheritance of eukaryotic genomes. It compromises several mechanisms, that invariably depend on core small non coding RNAs and that achieve dedicated sequence-specific functions. RNA silencing has been recognized to carry critical developmental, stress-response and bodyguard functions be coordinating the

Transcriptional and Post-transcriptional Regulation

Transcriptional and Post-transcriptional Regulation
  • Author : Ghedira Kais
  • Publisher : BoD – Books on Demand
  • Release : 10 October 2018
GET THIS BOOKTranscriptional and Post-transcriptional Regulation

This book focuses on the transcriptional and post-transcriptional gene regulations and presents a detailed portrait of many novel aspects related to highlighting the importance of key TFs in some vital biological processes, the role of certain TFs to control some infectious diseases, the role of non-coding RNAs in controlling mRNA expression, the involvement of these non-coding RNAs in diseases, and the interplay between TFs and microRNAs as key players for gene expression regulation giving a complete picture of how genes

RNA Biology

RNA Biology
  • Author : Gunter Meister
  • Publisher : Wiley-VCH
  • Release : 16 May 2011
GET THIS BOOKRNA Biology

Written with biologists, biochemists and other molecular scientists in mind, this volume meets the long-felt need for a textbook dedicated to the topic and recreates the excitement surrounding the scientific revolution sparked by the discovery of RNA interference in 1998. Students and instructors alike will profit from the author's exclusive first-hand knowledge, drawing on his breakthrough discoveries at the Tuschl lab at Rockefeller University. Gunter Meister abandons the traditionalist treatment of nucleic acids found in most biochemistry and molecular biology texts,

Long Non-coding RNAs in Plants

Long Non-coding RNAs in Plants
  • Author : Santosh Kumar Upadhyay
  • Publisher : Academic Press
  • Release : 20 November 2020
GET THIS BOOKLong Non-coding RNAs in Plants

Long Non-coding RNAs in Plants: Roles in Development and Stress provides the most recent advances in LncRNAs, including identification, characterization, and potential applications and uses. Introductory chapters include the discovery and development of lncRNAs, a comparative analysis of coding versus non-coding lncRNAs, and the role of lncRNAs in abiotic and biotic stress management. The book then provides methodology and protocols for identification and characterization, followed by chapters covering the various different applications of lncRNAs. Written by leading experts, this book