Computational Non coding RNA Biology

Computational Non-coding RNA Biology is a resource for the computation of non-coding RNAs. The book covers computational methods for the identification and quantification of non-coding RNAs, including miRNAs, tasiRNAs, phasiRNAs, lariat originated circRNAs and back-spliced circRNAs, the identification of miRNA/siRNA targets, and the identification of mutations and editing sites in miRNAs. The book introduces basic ideas of computational methods, along with their detailed computational steps, a critical component in the development of high throughput sequencing technologies for identifying different classes of non-coding RNAs and predicting the possible functions of these molecules. Finding, quantifying, and visualizing non-coding RNAs from high throughput sequencing datasets at high volume is complex. Therefore, it is usually possible for biologists to complete all of the necessary steps for analysis. Presents a comprehensive resource of computational methods for the identification and quantification of non-coding RNAs Introduces 23 practical computational pipelines for various topics of non-coding RNAs Provides a guide to assist biologists and other researchers dealing with complex datasets Introduces basic computational methods and provides guidelines for their replication by researchers Offers a solution to researchers approaching large and complex sequencing datasets

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  • Author : Yun Zheng
  • Publisher : Academic Press
  • Pages : 320 pages
  • ISBN : 0128143665
  • Rating : 4/5 from 21 reviews
CLICK HERE TO GET THIS BOOKComputational Non coding RNA Biology

Computational Non-coding RNA Biology

Computational Non-coding RNA Biology
  • Author : Yun Zheng
  • Publisher : Academic Press
  • Release : 14 September 2018
GET THIS BOOKComputational Non-coding RNA Biology

Computational Non-coding RNA Biology is a resource for the computation of non-coding RNAs. The book covers computational methods for the identification and quantification of non-coding RNAs, including miRNAs, tasiRNAs, phasiRNAs, lariat originated circRNAs and back-spliced circRNAs, the identification of miRNA/siRNA targets, and the identification of mutations and editing sites in miRNAs. The book introduces basic ideas of computational methods, along with their detailed computational steps, a critical component in the development of high throughput sequencing technologies for identifying different

Long Noncoding RNAs in Plants

Long Noncoding RNAs in Plants
  • Author : Santosh Kumar Upadhyay
  • Publisher : Academic Press
  • Release : 13 November 2020
GET THIS BOOKLong Noncoding RNAs in Plants

The growth of human population has increased the demand for improved yield and quality of crops and horticultural plants. However, plant productivity continues to be threatened by stresses such as heat, cold, drought, heavy metals, UV radiations, bacterial and fungal pathogens, and insect pests. Long noncoding RNAs are associated with various developmental pathways, regulatory systems, abiotic and biotic stress responses and signaling, and can provide an alternative strategy for stress management in plants. Long Noncoding RNAs in Plants: Roles in

Computational Biology of Non-Coding RNA

Computational Biology of Non-Coding RNA
  • Author : Xin Lai,Shailendra K. Gupta,Julio Vera
  • Publisher : Humana Press
  • Release : 04 February 2019
GET THIS BOOKComputational Biology of Non-Coding RNA

This volume details a collection of state-of-art methods including identification of novel ncRNAs and their targets, functional annotation and disease association in different biological contexts. Chapters guide readers through an overview of disease-specific ncRNAs, computational methods and workflows for ncRNA discovery, annotation based on high-throughput sequencing data, bioinformatics tools and databases for ncRNA analyses, network-based methods, and kinetic modelling of ncRNA-mediated gene regulation. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective

Long Non Coding RNA Biology

Long Non Coding RNA Biology
  • Author : M.R.S. Rao
  • Publisher : Springer
  • Release : 16 August 2017
GET THIS BOOKLong Non Coding RNA Biology

This contributed volume offers a comprehensive and detailed overview of the various aspects of long non-coding RNAs and discusses their emerging significance. Written by leading experts in the field, it motivates young researchers around the globe, and offers graduate and postgraduate students fascinating insights into genes and their regulation in eukaryotes and higher organisms.

RNA-Based Regulation in Human Health and Disease

RNA-Based Regulation in Human Health and Disease
  • Author : Anonim
  • Publisher : Academic Press
  • Release : 19 August 2020
GET THIS BOOKRNA-Based Regulation in Human Health and Disease

RNA-based Regulation in Human Health and Disease offers an in-depth exploration of RNA mediated genome regulation at different hierarchies. Beginning with multitude of canonical and non-canonical RNA populations, especially noncoding RNA in human physiology and evolution, further sections examine the various classes of RNAs (from small to large noncoding and extracellular RNAs), functional categories of RNA regulation (RNA-binding proteins, alternative splicing, RNA editing, antisense transcripts and RNA G-quadruplexes), dynamic aspects of RNA regulation modulating physiological homeostasis (aging), role of RNA

Applications of RNA-Seq and Omics Strategies

Applications of RNA-Seq and Omics Strategies
  • Author : Fabio Marchi,Priscila Cirillo,Elvis Cueva Mateo
  • Publisher : BoD – Books on Demand
  • Release : 13 September 2017
GET THIS BOOKApplications of RNA-Seq and Omics Strategies

The large potential of RNA sequencing and other "omics" techniques has contributed to the production of a huge amount of data pursuing to answer many different questions that surround the science's great unknowns. This book presents an overview about powerful and cost-efficient methods for a comprehensive analysis of RNA-Seq data, introducing and revising advanced concepts in data analysis using the most current algorithms. A holistic view about the entire context where transcriptome is inserted is also discussed here encompassing biological

Cancer and Noncoding RNAs

Cancer and Noncoding RNAs
  • Author : Jayprokas Chakrabarti,Sanga Mitra
  • Publisher : Academic Press
  • Release : 13 October 2017
GET THIS BOOKCancer and Noncoding RNAs

Cancer and Noncoding RNAs offers an in-depth exploration of noncoding RNAs and their role in epigenetic regulation of complex human disease, most notably cancer. In addition to examining microRNAs, this volume provides a unique evaluation of more recently profiled noncoding RNAs now implicated in carcinogenesis, including lncRNAs, piRNAs, circRNAs, and tRNAs, identifying differences in function between these noncoding RNAs and how they interact with the rest of the epigenome. A broad range of chapters from experts in the field detail

Non-coding RNAs in Cardiovascular Diseases

Non-coding RNAs in Cardiovascular Diseases
  • Author : Junjie Xiao
  • Publisher : Springer Nature
  • Release : 13 April 2020
GET THIS BOOKNon-coding RNAs in Cardiovascular Diseases

This book presents the latest research on non-coding RNAs in cardiovascular disease, a major cause of death worldwide. Non-coding RNAs play a significant role in development, proliferation, differentiation and apoptosis. Since altered non-coding RNA expression is often associated with various diseases, their potential use in diagnostics, prognostics and therapeutics is an important current area of study. The book consists of six parts: 1) An overview of non-coding RNAs and cardiovascular system, 2) Bioinformatics and interactions, 3) Non-coding RNA regulation in cardiovascular system, 4) Non-coding

Non Coding RNAs in Plants

Non Coding RNAs in Plants
  • Author : Volker A. Erdmann,Jan Barciszewski
  • Publisher : Springer Science & Business Media
  • Release : 20 July 2011
GET THIS BOOKNon Coding RNAs in Plants

In the most recent years, each of the RNA silencing pathways of plants have appeared to generate ncRNAs with dedicated functions, specialized biological activities and specific functional scopes. RNA silencing plays a crucial role in coordinating the expression, stability, protection and inheritance of eukaryotic genomes. It compromises several mechanisms, that invariably depend on core small non coding RNAs and that achieve dedicated sequence-specific functions. RNA silencing has been recognized to carry critical developmental, stress-response and bodyguard functions be coordinating the

Long Non-Coding RNAs in Cancer

Long Non-Coding RNAs in Cancer
  • Author : Alfons Navarro
  • Publisher : Unknown Publisher
  • Release : 22 May 2022
GET THIS BOOKLong Non-Coding RNAs in Cancer

This volume presents techniques needed for the study of long non-coding RNAs (lncRNAs) in cancer from their identification to functional characterization. Chapters guide readers through identification of lncRNA expression signatures in cancer tissue or liquid biopsies by RNAseq, single Cell RNAseq, Phospho RNAseq or Nanopore Sequencing techniques; validation of lncRNA signatures by Real time PCR, digital PCR or in situ hybridization; and functional analysis by siRNA or CRISPR based methods for lncRNA silencing or overexpression. Lipid based nanoparticles for delivery

Long Non-Coding RNA

Long Non-Coding RNA
  • Author : Syed Mudasir Andrabi,Nazir Ahmad Ganai
  • Publisher : Cambridge Scholars Publishing
  • Release : 03 September 2020
GET THIS BOOKLong Non-Coding RNA

Long non-coding RNAs (LncRNAs) were originally regarded as “noise” in the genome due to their lack of protein-encoding capacity. However, their roles are now understood to cover various biological functions like gene regulation, cell proliferation, survival, differentiation, and chromatin remodeling. As an emerging group of non-coding RNA molecules, LncRNAs are involved in diverse diseases like cancer, cardiovascular, autoimmune, hormonal disorders, neurodegeneration, and infection, among others. However, knowledge of the mechanisms by which they act is still ambiguous. As such, this

Kernel Methods in Computational Biology

Kernel Methods in Computational Biology
  • Author : Managing Director of the Max Planck Institute for Biological Cybernetics in Tubingen Germany Profe Bernhard Scholkopf,Sorin Istrail,Pavel A. Pevzner
  • Publisher : MIT Press
  • Release : 22 May 2022
GET THIS BOOKKernel Methods in Computational Biology

A Primer on Molecular Biology. A Primer on Kernel Methods. Support Vector Machine Applications in Computational Biology. Inexact Matching String Kernels for Protein Classification. Fast Kernels for String and Tree Matching. Local Alignment Kernels for Biological Sequences. Kernels for Graphs. Diffusion Kernels. A Kernel for Protein Secondary Structure Prediction. Heterogeneous Data Comparsion and Gene Selection with Kernel Canonical Correlation Analysis. Kernel-Based Integration of Genomic Data Using Semdefinite Programming. Protein Classification via Kernel Matrix Completion. Accurate Splice Site Detection for Caenorhabditid

Gene Expression Profiling in Cancer

Gene Expression Profiling in Cancer
  • Author : Dimitrios Vlachakis
  • Publisher : BoD – Books on Demand
  • Release : 19 June 2019
GET THIS BOOKGene Expression Profiling in Cancer

The contribution of modern-day genetics in designing efficient gene expression profiles for cancer is immense. The progress of technology and science in recent years provides the opportunity for discovery and application of new techniques for treating various diseases that affect humanity. Methods for finding and analyzing the profile of gene expression of infected cells give scientists the ability to develop more targeted and effective treatments, especially for diseases such as cancer. The development of gene expression profiling is one of

Plant Long Non-Coding RNAs

Plant Long Non-Coding RNAs
  • Author : Julia A. Chekanova,Hsiao-Lin V. Wang
  • Publisher : Humana Press
  • Release : 20 April 2019
GET THIS BOOKPlant Long Non-Coding RNAs

This volume focuses on various approaches to studying long non-coding RNAs (lncRNAs), including techniques for finding lncRNAs, localization, and observing their functions. The chapters in this book cover how to catalog lncRNAs in various plant species; determining subcellular localization; protein interactions; structures; and RNA modifications. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and

Computational Genomics with R

Computational Genomics with R
  • Author : Altuna Akalin
  • Publisher : CRC Press
  • Release : 16 December 2020
GET THIS BOOKComputational Genomics with R

Computational Genomics with R provides a starting point for beginners in genomic data analysis and also guides more advanced practitioners to sophisticated data analysis techniques in genomics. The book covers topics from R programming, to machine learning and statistics, to the latest genomic data analysis techniques. The text provides accessible information and explanations, always with the genomics context in the background. This also contains practical and well-documented examples in R so readers can analyze their data by simply reusing the