Cytogenomics

Cytogenomics demonstrates that chromosomes are crucial in understanding the human genome and that new high-throughput approaches are central to advancing cytogenetics in the 21st century. After an introduction to (molecular) cytogenetics, being the basic of all cytogenomic research, this book highlights the strengths and newfound advantages of cytogenomic research methods and technologies, enabling researchers to jump-start their own projects and more effectively gather and interpret chromosomal data. Methods discussed include banding and molecular cytogenetics, molecular combing, molecular karyotyping, next-generation sequencing, epigenetic study approaches, optical mapping/karyomapping, and CRISPR-cas9 applications for cytogenomics. The book’s second half demonstrates recent applications of cytogenomic techniques, such as characterizing 3D chromosome structure across different tissue types and insights into multilayer organization of chromosomes, role of repetitive elements and noncoding RNAs in human genome, studies in topologically associated domains, interchromosomal interactions, and chromoanagenesis. This book is an important reference source for researchers, students, basic and translational scientists, and clinicians in the areas of human genetics, genomics, reproductive medicine, gynecology, obstetrics, internal medicine, oncology, bioinformatics, medical genetics, and prenatal testing, as well as genetic counselors, clinical laboratory geneticists, bioethicists, and fertility specialists. Offers applied approaches empowering a new generation of cytogenomic research using a balanced combination of classical and advanced technologies Provides a framework for interpreting chromosome structure and how this affects the functioning of the genome in health and disease Features chapter contributions from international leaders in the field

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  • Author : Thomas Liehr
  • Publisher : Academic Press
  • Pages : 428 pages
  • ISBN : 0128235802
  • Rating : 4/5 from 21 reviews
CLICK HERE TO GET THIS BOOKCytogenomics

Cytogenomics

Cytogenomics
  • Author : Thomas Liehr
  • Publisher : Academic Press
  • Release : 25 May 2021
GET THIS BOOKCytogenomics

Cytogenomics demonstrates that chromosomes are crucial in understanding the human genome and that new high-throughput approaches are central to advancing cytogenetics in the 21st century. After an introduction to (molecular) cytogenetics, being the basic of all cytogenomic research, this book highlights the strengths and newfound advantages of cytogenomic research methods and technologies, enabling researchers to jump-start their own projects and more effectively gather and interpret chromosomal data. Methods discussed include banding and molecular cytogenetics, molecular combing, molecular karyotyping, next-generation sequencing,

The AGT Cytogenetics Laboratory Manual

The AGT Cytogenetics Laboratory Manual
  • Author : Marilyn S. Arsham,Margaret J. Barch,Helen J. Lawce
  • Publisher : John Wiley & Sons
  • Release : 24 April 2017
GET THIS BOOKThe AGT Cytogenetics Laboratory Manual

Cytogenetics is the study of chromosome morphology, structure, pathology, function, and behavior. The field has evolved to embrace molecular cytogenetic changes, now termed cytogenomics. Cytogeneticists utilize an assortment of procedures to investigate the full complement of chromosomes and/or a targeted region within a specific chromosome in metaphase or interphase. Tools include routine analysis of G-banded chromosomes, specialized stains that address specific chromosomal structures, and molecular probes, such as fluorescence in situ hybridization (FISH) and chromosome microarray analysis, which employ

Human Interphase Chromosomes

Human Interphase Chromosomes
  • Author : Ivan Iourov,Svetlana Vorsanova,Yuri Yurov
  • Publisher : Springer Nature
  • Release : 29 January 2021
GET THIS BOOKHuman Interphase Chromosomes

This second edition focuses on the study of human interphase chromosomes and its relation to health and disease. Orchestrated organization and behavior of the human genome in interphase nuclei at chromosomal level has been repeatedly shown to play a significant role in almost all basic biological processes involved in the processing and inheritance of genetic information within and between species. Accordingly, post-genomic bioscience appeals to basic and applied studies of interphase nuclei genetics and genomics with special attention to interphase

Genome and Genomics

Genome and Genomics
  • Author : K. V. Chaitanya
  • Publisher : Springer Nature
  • Release : 17 November 2019
GET THIS BOOKGenome and Genomics

This book provides a detailed and up-to-dated information on the genomes belonging to three major life forms on Earth – archaea, prokaryotes and eukaryotes. Each section describes about the genome of a specific group of organisms, such as viruses, archaea, bacteria, eukaryotes and organellar genomes. Individual chapters provide details of their organization, structure, evolution, sequencing strategies and functions. Further, this book discusses the technologies that are applied for genome sequencing; assembly, annotation and gene prediction. Other topics include the genomes of

PlantOmics: The Omics of Plant Science

PlantOmics: The Omics of Plant Science
  • Author : Debmalya Barh,Muhammad Sarwar Khan,Eric Davies
  • Publisher : Springer
  • Release : 18 March 2015
GET THIS BOOKPlantOmics: The Omics of Plant Science

PlantOmics: The Omics of Plant Science provides a comprehensive account of the latest trends and developments of omics technologies or approaches and their applications in plant science. Thirty chapters written by 90 experts from 15 countries are included in this state-of-the-art book. Each chapter describes one topic/omics such as: omics in model plants, spectroscopy for plants, next generation sequencing, functional genomics, cyto-metagenomics, epigenomics, miRNAomics, proteomics, metabolomics, glycomics, lipidomics, secretomics, phenomics, cytomics, physiomics, signalomics, thiolomics, organelle omics, micro morphomics, microbiomics, cryobionomics, nanotechnology,

Cytogenetics

Cytogenetics
  • Author : Marcelo L. Larramendy,Sonia Soloneski
  • Publisher : BoD – Books on Demand
  • Release : 10 May 2019
GET THIS BOOKCytogenetics

Cytogenetics - Past, Present, and Further Perspectives discusses events that influenced the development of cytogenetics as a specialty within biology, with special attention paid to methodological achievements developed worldwide that have driven the field forward. Improvements to the resolution of chromosome analysis followed closely the introduction of innovative analytical technologies. In that sense, this book reviews and provides a brief account of the structure of chromosomes and stresses the high structural conservation in different species with an emphasis on aspects

Repetitive DNA

Repetitive DNA
  • Author : Manuel A. Garrido-Ramos
  • Publisher : Karger Medical and Scientific Publishers
  • Release : 24 May 2022
GET THIS BOOKRepetitive DNA

The experimental data that have been generated using new molecular techniques associated with the completion of genome projects have changed our perception of the structural features, functional implications and evolutionary dynamics of repetitive DNA sequences. This volume of Genome Dynamics provides a valuable update on recent developments in research into multigene families, centromeres, telomeres, microsatellite DNA, satellite DNA, and transposable elements. Each chapter presents a review by distinguished experts and analyzes repetitive DNA diversity and abundance, as well as the

The Principles of Clinical Cytogenetics

The Principles of Clinical Cytogenetics
  • Author : Steven L. Gersen,Martha B. Keagle
  • Publisher : Springer Science & Business Media
  • Release : 26 March 2013
GET THIS BOOKThe Principles of Clinical Cytogenetics

In this thoroughly revised and expanded third edition of the highly praised classic, The Principles of Clinical Cytogenetics, a panel of hands-on experts update their descriptions of the basic concepts and interpretations involved in chromosome analysis to include the many advances that have occurred in the field. Among the highlights are a full chapter devoted to advances in chromosome microarray, soon to become a standard of care in this field, as well as an update on chromosome nomenclature as reflected

Iscn 2020

Iscn 2020
  • Author : Jean McGowan-Jordan,Ros J. Hastings,Sarah Moore
  • Publisher : Unknown Publisher
  • Release : 31 December 2020
GET THIS BOOKIscn 2020

This reprint of 'Cytogenetic and Genome Research' contains contributions discussing the subject in-depth. 'Cytogenetic and Genome Research' is a well-respected, international peer-reviewed journal in genetics.

ISCN 2013

ISCN 2013
  • Author : International Standing Committee on Human Cytogenetic Nomenclature
  • Publisher : Karger Medical and Scientific Publishers
  • Release : 24 May 2022
GET THIS BOOKISCN 2013

This publication extends the now classic system of human cytogenetic nomenclature prepared by an expert committee and published in collaboration with Cytogenetic and Genome Research' since 1963. Revised and finalized by the ISCN Committee and its advisors at a meeting in Seattle, Wash., in April 2012, the ISCN 2013 updates, revises and incorporates all previous human cytogenetic nomenclature recommendations into one systematically organized publication that supersedes all previous ISCN recommendations. There are several new features in ISCN 2013: an update of the microarray nomenclature,

Molecular Diagnostics

Molecular Diagnostics
  • Author : George P. Patrinos,Wilhelm Ansorge,Phillip B. Danielson
  • Publisher : Academic Press
  • Release : 27 October 2016
GET THIS BOOKMolecular Diagnostics

Molecular Diagnostics, Third Edition, focuses on the technologies and applications that professionals need to work in, develop, and manage a clinical diagnostic laboratory. Each chapter contains an expert introduction to each subject that is next to technical details and many applications for molecular genetic testing that can be found in comprehensive reference lists at the end of each chapter. Contents are divided into three parts, technologies, application of those technologies, and related issues. The first part is dedicated to the

Cytogenetic Laboratory Management

Cytogenetic Laboratory Management
  • Author : Susan Mahler Zneimer
  • Publisher : John Wiley & Sons
  • Release : 27 January 2017
GET THIS BOOKCytogenetic Laboratory Management

Cytogenetic Laboratory Management: Chromosomal, FISH and Microarray-Based Best Practices and Procedures is a practical guide that describes how to develop and implement best practice processes and procedures in the genetic laboratory setting. The text first describes good laboratory practices, including quality management, design control of tests and FDA guidelines for laboratory developed tests, and pre-clinical validation study designs. The second focus of the book describes best practices for staffing and training, including cost of testing, staffing requirements, process improvement using

Cancer Cytogenetics

Cancer Cytogenetics
  • Author : Sverre Heim,Felix Mitelman
  • Publisher : John Wiley & Sons
  • Release : 29 June 2015
GET THIS BOOKCancer Cytogenetics

The first three editions of this acclaimed book presented a much-needed conceptual synthesis of this rapidly moving field. Now, Cancer Cytogenetics, Fourth Edition, offers a comprehensive, expanded, and up-to-date review of recent dramatic advances in this area, incorporating a vast amount of new data from the latest basic and clinical investigations. New contributors reflecting broader international authorship and even greater expertise Greater emphasis throughout on the clinical importance and application of information about cytogenetic and molecular aberrations Includes a complete

Iscn 2016

Iscn 2016
  • Author : J. McGowan-Jordan,M. Schmid,A. Simons
  • Publisher : Unknown Publisher
  • Release : 11 May 2016
GET THIS BOOKIscn 2016

The 2016 edition of the International System for Human Cytogenomic Nomenclature (ISCN 2016) offers standard nomenclature that is used to describe any genomic rearrangement identified by techniques ranging from karyotyping to FISH, microarray, various region specific assays, and DNA sequencing. Suggestions from the international cytogenetics community have been reviewed by the Standing Committee, an international group of experts, nominated by their peers. This updated edition offers: * many new examples, particularly for microarray and region specific assays * trackable changes in the main text