Detection of Drugs and Their Metabolites in Oral Fluid

Detection of Drugs and Their Metabolites in Oral Fluid presents the analytical chemistry methods used for the detection and quantification of drugs and their metabolites in human oral fluid. The authors summarize the state of the science, including its strengths, weaknesses, unmet methodological needs, and cutting-edge trends. This volume covers the salient aspects of oral fluid drug testing, including specimen collection and handling, initial testing, point of collection testing (POCT), specimen validity testing (SVT), and confirmatory and proficiency testing. Analytes discussed include amphetamines, cannabinoids, cocaine, opiates, phencyclidine, cannabimimetics, and miscellaneous drugs. This practical guide helps users turn knowledge into practice, moving logically from an outline of the problem, to the evaluation of the appropriateness of oral fluid as a test medium, and finally to a consideration of detection methods and their validation and employment. Compares different collection and testing systems to assist readers involved in clinical or forensic practice in selecting oral fluid as the matrix of choice Provides a sound basis for the detection of drugs and their metabolites in oral fluid and the interpretation of both positive and negative Places the need, or lack thereof, for specimen validity testing and confirmation testing in context with the purposes of oral fluid testing Describes drugs and drug classes that can be tested, along with useful information on a patient/donor's drug status

Produk Detail:

  • Author : Robert M. White
  • Publisher : Emerging Issues in Analytical Chemistry
  • Pages : 140 pages
  • ISBN : 9780128145951
  • Rating : 4/5 from 21 reviews
CLICK HERE TO GET THIS BOOKDetection of Drugs and Their Metabolites in Oral Fluid

Detection of Drugs and Their Metabolites in Oral Fluid

Detection of Drugs and Their Metabolites in Oral Fluid
  • Author : Robert M. White,Christine M. Moore
  • Publisher : Emerging Issues in Analytical Chemistry
  • Release : 01 February 2018
GET THIS BOOKDetection of Drugs and Their Metabolites in Oral Fluid

Detection of Drugs and Their Metabolites in Oral Fluid presents the analytical chemistry methods used for the detection and quantification of drugs and their metabolites in human oral fluid. The authors summarize the state of the science, including its strengths, weaknesses, unmet methodological needs, and cutting-edge trends. This volume covers the salient aspects of oral fluid drug testing, including specimen collection and handling, initial testing, point of collection testing (POCT), specimen validity testing (SVT), and confirmatory and proficiency testing. Analytes

Detection of Drugs and Their Metabolites in Oral Fluid

Detection of Drugs and Their Metabolites in Oral Fluid
  • Author : Robert M. White,Christine M. Moore
  • Publisher : Elsevier
  • Release : 23 February 2018
GET THIS BOOKDetection of Drugs and Their Metabolites in Oral Fluid

Detection of Drugs and Their Metabolites in Oral Fluid presents the analytical chemistry methods used for the detection and quantification of drugs and their metabolites in human oral fluid. The authors summarize the state of the science, including its strengths, weaknesses, unmet methodological needs, and cutting-edge trends. This volume covers the salient aspects of oral fluid drug testing, including specimen collection and handling, initial testing, point of collection testing (POCT), specimen validity testing (SVT), and confirmatory and proficiency testing. Analytes

Critical Issues in Alcohol and Drugs of Abuse Testing

Critical Issues in Alcohol and Drugs of Abuse Testing
  • Author : Amitava Dasgupta
  • Publisher : Academic Press
  • Release : 10 January 2019
GET THIS BOOKCritical Issues in Alcohol and Drugs of Abuse Testing

Critical Issues in Alcohol and Drugs of Abuse Testing, Second Edition, addresses the general principles and technological advances for measuring drugs and alcohol, along with the pitfalls of drugs of abuse testing. Many designer drugs, for example, are not routinely tested in drugs of abuse panels and may go undetected in a drug test. This updated edition is a must-have for clinical pathologists, toxicologists, clinicians, and medical review officers and regulators, bridging the gap between technical and clinical information. Topics

Drugs of Abuse

Drugs of Abuse
  • Author : Raphael C. Wong,Harley Y. Tse
  • Publisher : Springer Science & Business Media
  • Release : 05 November 2007
GET THIS BOOKDrugs of Abuse

A comprehensive review of the science of drug testing in all its aspects, placing emphasis on technologies that use body fluids other than urine for determining the presence of drugs of abuse. The authors discuss the various body fluid specimens suitable for testing for illicit drugs-particularly saliva, sweat, and hair-describe the structural and manufacturing aspects of on-site testing devices based on lateral flow immunoassay, and detail the pitfalls of using these specimens. They also discuss in detail the problem of

Principles of Forensic Toxicology

Principles of Forensic Toxicology
  • Author : Barry S. Levine,SARAH KERRIGAN
  • Publisher : Springer Nature
  • Release : 13 August 2020
GET THIS BOOKPrinciples of Forensic Toxicology

The fifth edition of the best-selling Principles in Forensic Toxicology continues in the tradition of excellence in academic publishing. With over 10 years of classroom-tested and continually updated content, the new edition contains significant updates and 7 new chapters on new topics including drug-facilitated crimes, derivatization, quantitation, measurement uncertainty/traceability, statistics, oral fluid testing, and drugs in embalmed specimens. Part One covers the major sub-disciplines of forensic toxicology in addition to pharmacological concepts. Part Two addresses specimen preparation, laboratory testing and instrumental

Liquid Chromatography

Liquid Chromatography
  • Author : C. Kostakis,P. Harpas,P. Stockham
  • Publisher : Elsevier Inc. Chapters
  • Release : 08 January 2013
GET THIS BOOKLiquid Chromatography

Practitioners of forensic toxicology are expected to detect, confirm, and quantify a chemically diverse range of drugs and poisons covering a number of orders of magnitude in concentration in challenging biological matrices. Developments in LC–MS have enabled a wider range of compounds to be analyzed using fewer extraction processes, practically eliminating the requirement for derivatization steps and with fewer instrumental analysis stages. This chapter provides the reader with a broad overview of the current capabilities offered by LC in

Handbook of HPLC

Handbook of HPLC
  • Author : Danilo Corradini
  • Publisher : CRC Press
  • Release : 19 April 2016
GET THIS BOOKHandbook of HPLC

High performance liquid chromatography (HPLC) is one of the most widespread analytical and preparative scale separation techniques used for both scientific investigations and industrial and biomedical analysis. Now in its second edition, this revised and updated version of the Handbook of HPLC examines the new advances made in this field since the

Analytical Techniques in Biosciences

Analytical Techniques in Biosciences
  • Author : Chukwuebuka Egbuna,Kingsley C. Patrick-Iwuanyanwu,Muhammad Ajmal Shah,Jonathan C. Ifemeje,Azhar Rasul
  • Publisher : Academic Press
  • Release : 21 October 2021
GET THIS BOOKAnalytical Techniques in Biosciences

Analytical Techniques in Biosciences: From Basics to Applications presents comprehensive and up-to-date information on the various analytical techniques obtainable in bioscience research laboratories across the world. This book contains chapters that discuss the basic bioanalytical protocols and sample preparation guidelines. Commonly encountered analytical techniques, their working principles, and applications were presented. Techniques, considered in this book, include centrifugation techniques, electrophoretic techniques, chromatography, titrimetry, spectrometry, and hyphenated techniques. Subsequent chapters emphasize molecular weight determination and electroanalytical techniques, biosensors, and enzyme assay

Analysis of Cocaine, Heroin, and Their Metabolites in Saliva

Analysis of Cocaine, Heroin, and Their Metabolites in Saliva
  • Author : David A. Kidwell,NAVAL RESEARCH LAB WASHINGTON DC.
  • Publisher : Unknown Publisher
  • Release : 17 May 1990
GET THIS BOOKAnalysis of Cocaine, Heroin, and Their Metabolites in Saliva

Methods have been developed to analyze for cocaine, heroin and their metabolites in human saliva and the results compared to urinalysis. Analysis of 26 samples showed that 14 positive by urinalysis and 16 positive by saliva analysis. Thus, saliva testing may be competitive to urine testing for detection of drug use. Only a small fraction of the saliva is necessary for the analysis so that further testing may be employed. Also, the metabolite profiles are shown for further analytical development. Keywords: Drugs of

Handbook of Analytical Therapeutic Drug Monitoring and Toxicology (1996)

Handbook of Analytical Therapeutic Drug Monitoring and Toxicology (1996)
  • Author : Steven H.Y. Wong,Irving Sunshine
  • Publisher : CRC Press
  • Release : 22 November 2017
GET THIS BOOKHandbook of Analytical Therapeutic Drug Monitoring and Toxicology (1996)

Adapting modern advances in analytical techniques to daily laboratory practices challenges many toxicologists, clinical laboratories, and pharmaceutical scientists. The Handbook of Analytical Therapeutic Drug Monitoring and Toxicology helps you keep abreast of the innovative changes that can make your laboratory - and the studies undertaken in it - a success. This volume simplifies your search for appropriate techniques, describes recent contributions from leading investigators, and provides valuable evaluations and advice.

Forensic Science

Forensic Science
  • Author : Anonim
  • Publisher : Elsevier
  • Release : 22 September 2011
GET THIS BOOKForensic Science

The book presents the applications of separation methods, manly chromatography, in forensic practice. The first part, devoted to forensic toxicology, contains reviews on forensic relevant groups of compounds, like: Opiate agonists, cocaine, amphetamines, hallucinogens, cannabinoids, sedatives and hypnotics, antidepressive and antipsychotic drugs, analgesics, antidiabetics, muscle relaxants, and mushroom toxins. In these parts, the preliminary immunochemical tests were also included, together with separation methods. Screening procedures used in forensic toxicology were presented in separate chapters on forensic screening with GC, GC-MS,

Forensic Toxicology

Forensic Toxicology
  • Author : Susannah Davies,Atholl Johnston,David Holt
  • Publisher : Royal Society of Chemistry
  • Release : 15 March 2019
GET THIS BOOKForensic Toxicology

New designer drugs, access to databases, and changing availability of samples for analysis have changed the face of modern forensic toxicology in recent years. Forensic Toxicology: Drug Use and Misuse brings together the latest information direct from experts in each sub-field of the discipline providing a broad overview of current thinking and the most innovative approaches to case studies. The text begins with an in-depth discussion of pharmaco­epidemiology, including information on the value of nationwide databases in forensic toxicology.

Identification and Quantification of Drugs, Metabolites, Drug Metabolizing Enzymes, and Transporters

Identification and Quantification of Drugs, Metabolites, Drug Metabolizing Enzymes, and Transporters
  • Author : Shuguang Ma,Swapan Chowdhury
  • Publisher : Elsevier
  • Release : 09 July 2020
GET THIS BOOKIdentification and Quantification of Drugs, Metabolites, Drug Metabolizing Enzymes, and Transporters

Identification and Quantification of Drugs, Metabolites, Drug Metabolizing Enzymes, and Transporters, Second Edition, is completely updated to provide an overview of the last decade’s numerous advances in analytical technologies for detection and quantification of drugs, metabolites, and biomarkers. This new edition goes beyond LC-MS and features all-new chapters on how to evaluate drug absorption, distribution, metabolism, and excretion, potential for hepatic and renal toxicity, immunogenicity of biotherapeutics and translational tools for predicting human dosage, safety and efficacy of small

Particulates Matter

Particulates Matter
  • Author : Vikram Rao,William Vizuete
  • Publisher : Elsevier
  • Release : 28 November 2020
GET THIS BOOKParticulates Matter

A title in the Emerging Issues in Analytical Chemistry series, Particulates Matter: Impact, Measurement, and Remediation of Airborne Pollutants provides the latest technical findings in the study of particulate matter (PM). It links these findings to awareness-raising and actionable schemes for legislated remediation and engineered solutions. Written in an engaging and informative manner, the book begins with a multi-disciplinary overview of the major sources and unique classes of PM, detection techniques, and their impact, including molecular changes resulting in health