Electroporation Based Therapies for Cancer

Electroporation-Based Therapies for Cancer reviews electroporation-based clinical studies in hospitals for various cancer treatments, including melanomas, head and neck cancers, chest wall breast carcinomas, and colorectal cancers, as well as research studies in the lab using cell lines, primary cells, and animals. Cancer kills about one American per minute, amounting to over 500,000 deaths in the United States and millions, worldwide, each year. There is a critical need for safe, effective, and affordable alternative treatment modalities, especially for inoperable, recurring, and chemo-resistant cancers, that do not respond well to current treatment regimen. An electrical-pulse-mediated, enhanced drug delivery technique known as electroporation is one way to effectively treat these patients. This technique is especially suitable for low- and middle-income countries, where lack of infrastructure and resources leads to cancer diagnoses at late stages. This quick, safe, effective, economical, out-patient-based technique is a boon to these patients for palliative and other care with enhanced quality of life. This book features discussions by interdisciplinary authors—including practicing oncological surgeons, medical professionals, and academic and other researchers—of the basics and clinical medical applications of electroporation. Provides novel and recent clinical applications of electrochemotherapy for various cancers, including melanomas, sarcomas, superficial extreme melanoma, chest wall breast carcinoma, and colorectal cancers Extensive study of a number of cell lines, including human breast cancer, lung cancer, cervical cancer, leukemia, and mouse breast cancer using both reversible and irreversible electroporation techniques In vitro study of delivery of various commonly prescribed/administered breast cancer chemo and hormone drugs, such as Doxorubicin, Paclitaxel, Bleomycin, and Tamoxifen

Produk Detail:

  • Author : Raji Sundararajan
  • Publisher : Elsevier
  • Pages : 352 pages
  • ISBN : 1908818298
  • Rating : 4/5 from 21 reviews
CLICK HERE TO GET THIS BOOKElectroporation Based Therapies for Cancer

Electroporation-Based Therapies for Cancer

Electroporation-Based Therapies for Cancer
  • Author : Raji Sundararajan
  • Publisher : Elsevier
  • Release : 28 August 2014
GET THIS BOOKElectroporation-Based Therapies for Cancer

Electroporation-Based Therapies for Cancer reviews electroporation-based clinical studies in hospitals for various cancer treatments, including melanomas, head and neck cancers, chest wall breast carcinomas, and colorectal cancers, as well as research studies in the lab using cell lines, primary cells, and animals. Cancer kills about one American per minute, amounting to over 500,000 deaths in the United States and millions, worldwide, each year. There is a critical need for safe, effective, and affordable alternative treatment modalities, especially for inoperable, recurring, and

Gene Therapy of Cancer

Gene Therapy of Cancer
  • Author : Stanton L. Gerson,Edmund C. Lattime
  • Publisher : Elsevier
  • Release : 04 April 2002
GET THIS BOOKGene Therapy of Cancer

The Second Edition of Gene Therapy of Cancer provides crucial updates on the basic science and ongoing research in this field, examining the state of the art technology in gene therapy and its therapeutic applications to the treatment of cancer. The clinical chapters are improved to include new areas of research and more successful trials. Chapters emphasize the scientific basis of gene therapy using immune, oncogene, antisense, pro-drug activating, and drug resistance gene targets, while other chapters discuss therapeutic approaches

Irreversible Electroporation

Irreversible Electroporation
  • Author : Boris Rubinsky
  • Publisher : Springer Science & Business Media
  • Release : 25 November 2009
GET THIS BOOKIrreversible Electroporation

Non-thermal irreversible electroporation is a new minimally invasive surgical p- cedure with unique molecular selectivity attributes – in fact it may be considered the first clinical molecular surgery procedure. Non-thermal irreversible electro- ration is a molecular selective mode of cell ablation that employs brief electrical fields to produce nanoscale defects in the cell membrane, which can lead to cell death, without an effect on any of the other tissue molecules. The electrical fields can be produced through contact by insertion of

Immunization

Immunization
  • Author : Ning Wang,Ting Wang
  • Publisher : BoD – Books on Demand
  • Release : 28 November 2018
GET THIS BOOKImmunization

Immunization plays a key role in maintaining human health and each year, saves millions of lives from lethal pathogens and other fatal diseases in the most economical way, thanks to the advanced development of model vaccines. Subunit vaccines are regarded as a safer product than the whole microbe based-conventional vaccines and can be entrapped in various nanocarriers to form a vaccine adjuvant-delivery system (VADS) able to further boost their immunostimulatory activity. In this book, six groups of authors introduce immunization

Dendritic Cells

Dendritic Cells
  • Author : Svetlana P. Chapoval
  • Publisher : BoD – Books on Demand
  • Release : 07 November 2018
GET THIS BOOKDendritic Cells

Since their discovery in 1973 by Zanvil Cohn and Ralph Steinman (Nobel Prize in Physiology and Medicine, 2011), dendritic cells (DCs) continue to intrigue research scientists as their new markers, subpopulations and properties are being detected and the relevant literature is being doubled each year. This book combines the most comprehensive reviews of several critical aspects of DC biology and function written by a group of international experts in the field. The first section briefly discusses recent advances in DC subtypes, phenotypes,

Handbook of Electroporation

Handbook of Electroporation
  • Author : Damijan Miklavcic
  • Publisher : Springer
  • Release : 27 August 2017
GET THIS BOOKHandbook of Electroporation

This major reference work is a one-shot knowledge base on electroporation and the use of pulsed electric fields of high intensity and their use in biology, medicine, biotechnology, and food and environmental technologies. The Handbook offers a widespread and well-structured compilation of chapters ranging from the foundations to applications in industry and hospital. It is edited and written by most prominent researchers in the field. With regular updates and growing in its volume it is suitable for academic readers and

Advanced Electroporation Techniques in Biology and Medicine

Advanced Electroporation Techniques in Biology and Medicine
  • Author : Andrei G. Pakhomov,Damijan Miklavcic,Marko S. Markov
  • Publisher : CRC Press
  • Release : 02 June 2010
GET THIS BOOKAdvanced Electroporation Techniques in Biology and Medicine

A reflection of the intense study of the effects of electromagnetic fields on living tissues that has taken place during the last decades, Advanced Electroporation Techniques in Biology and Medicine summarizes most recent experimental findings and theories related to permeabilization of biomembranes by pulsed electric fields. Edited by experts and including contributions from pioneers in the field, the book focuses on biophysical mechanisms of electroporation and applications of this phenomenon in biomedical research and medicine. The field of electroporation is

EMBC 2004

EMBC 2004
  • Author : IEEE Engineering in Medicine and Biology Society. Conference
  • Publisher : Unknown Publisher
  • Release : 14 April 2021
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Electroporation Protocols

Electroporation Protocols
  • Author : Shulin Li,Jeffry Cutrera,Richard Heller,Justin Teissie
  • Publisher : Humana Press
  • Release : 27 August 2016
GET THIS BOOKElectroporation Protocols

Electroporation gene therapy, or gene electrotransfer, has evolved greatly over the last few decades as a result of the remarkable progress in genetic sequencing, gene array analysis, gene cloning, gene expression detection, DNA manufacture and discovery and synthesis of siRNA. Electroporation Protocols: Preclinical and Clinical Gene Medicine, Second Edition provides in-depth knowledge on the delivery of naked DNA and small-interfering RNA (siRNA) to the targeted cells, tissues, and animals for prevention and treatment of disease. It builds on the success

Tumor Vascularization

Tumor Vascularization
  • Author : Domenico Ribatti,Francesco Pezzella
  • Publisher : Academic Press
  • Release : 21 January 2020
GET THIS BOOKTumor Vascularization

Tumor Vascularization discusses the different types of growth of tumor blood vessels and their implications on research and healthcare. The book is divided into three parts: the first one, General Mechanisms, discusses different vessel growth mechanisms, such as sprouting angiogenesis, non-angiogenesis dependent growth, intussusceptive microvascular growth, vascular co-option and vasculogenic mimicry. The second and third parts, entitled Clinical Implications and Therapeutic Implications are dedicated to translating recent findings in this field to patient treatment and healthcare. This book is a