In Silico Lead Discovery

Computer-aided drug design and in silico screening have contributed to the discovery of several compounds that have either reached the market or entered clinical trials. In silico Lead Discovery is a compilation of the efforts of several experts on bioinf

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  • Author : Maria A. Miteva
  • Publisher : Bentham Science Publishers
  • Pages : 193 pages
  • ISBN : 1608051420
  • Rating : 4/5 from 21 reviews
CLICK HERE TO GET THIS BOOKIn Silico Lead Discovery

In-Silico Lead Discovery

In-Silico Lead Discovery
  • Author : Maria A. Miteva
  • Publisher : Bentham Science Publishers
  • Release : 23 May 2022
GET THIS BOOKIn-Silico Lead Discovery

Computer-aided drug design and in silico screening have contributed to the discovery of several compounds that have either reached the market or entered clinical trials. In silico Lead Discovery is a compilation of the efforts of several experts on bioinf

In Silico Drug Discovery and Design

In Silico Drug Discovery and Design
  • Author : Claudio N. Cavasotto
  • Publisher : CRC Press
  • Release : 06 August 2015
GET THIS BOOKIn Silico Drug Discovery and Design

In Silico Drug Discovery and Design: Theory, Methods, Challenges, and Applications provides a comprehensive, unified, and in-depth overview of the current methodological strategies in computer-aided drug discovery and design. Its main aims are to introduce the theoretical framework and algorithms, discuss the range of validity, strengths and limita

Frontiers in Drug Design and Discovery

Frontiers in Drug Design and Discovery
  • Author : Atta-ur- Rahman,Gary W. Caldwell, M. Iqbal Choudhary,Mark R. Player
  • Publisher : Bentham Science Publishers
  • Release : 13 December 2010
GET THIS BOOKFrontiers in Drug Design and Discovery

"Frontiers in Drug Design and Discovery" is an Ebook series devoted to publishing the latest and the most important advances in drug design and discovery. Eminent scientists write contributions on all areas of rational drug design and drug discovery inclu

Fragment-based Drug Discovery

Fragment-based Drug Discovery
  • Author : Daniel A. Erlanson,Wolfgang Jahnke,Raimund Mannhold,Hugo Kubinyi,Gerd Folkers
  • Publisher : John Wiley & Sons
  • Release : 23 February 2016
GET THIS BOOKFragment-based Drug Discovery

From its origins as a niche technique more than 15 years ago, fragment-based approaches have become a major tool for drug and ligand discovery, often yielding results where other methods have failed. Written by the pioneers in the field, this book provides a comprehensive overview of current methods and applications of fragment-based discovery, as well as an outlook on where the field is headed. The first part discusses basic considerations of when to use fragment-based methods, how to select targets, and

BioNMR in Drug Research

BioNMR in Drug Research
  • Author : Oliver Zerbe
  • Publisher : John Wiley & Sons
  • Release : 06 March 2006
GET THIS BOOKBioNMR in Drug Research

The vast progress made in the investigation of biomolecules using NMR has only recently been rewarded with the Nobel Prize for Kurt Wüthrich. Edited by a former coworker of Wüthrich, this book presents the theoretical background on NMR of biomolecules, plus the use of NMR techniques in determining the structures of proteins and nucleic acids. BioNMR spectroscopy offers a universal tool for examining the binding of an active substance to its target protein. Its use thereby benefits the

Glycogen Synthase Kinases—Advances in Research and Application: 2013 Edition

Glycogen Synthase Kinases—Advances in Research and Application: 2013 Edition
  • Author : Anonim
  • Publisher : ScholarlyEditions
  • Release : 21 June 2013
GET THIS BOOKGlycogen Synthase Kinases—Advances in Research and Application: 2013 Edition

Glycogen Synthase Kinases—Advances in Research and Application: 2013 Edition is a ScholarlyBrief™ that delivers timely, authoritative, comprehensive, and specialized information about ZZZAdditional Research in a concise format. The editors have built Glycogen Synthase Kinases—Advances in Research and Application: 2013 Edition on the vast information databases of ScholarlyNews.™ You can expect the information about ZZZAdditional Research in this book to be deeper than what you can access anywhere else, as well as consistently reliable, authoritative, informed, and relevant. The content of

Multi-Scale Approaches in Drug Discovery

Multi-Scale Approaches in Drug Discovery
  • Author : Alejandro Speck-Planche
  • Publisher : Elsevier
  • Release : 14 February 2017
GET THIS BOOKMulti-Scale Approaches in Drug Discovery

Drug discovery is an expensive, time-consuming process and the modern drug discovery community is constantly challenged not only with discovering novel bioactive agents to combat resistance from known diseases and fight against new ones, but to do so in a way that is economically effective. Advances in both experimental and theoretical/computational methods envisage that the greatest challenges in drug discovery can be most successfully addressed by using a multi-scale approach, drawing on the specialties of a whole host of

Targeted Cancer Treatment in Silico

Targeted Cancer Treatment in Silico
  • Author : Natalia L. Komarova,Dominik Wodarz
  • Publisher : Springer Science & Business Media
  • Release : 19 November 2013
GET THIS BOOKTargeted Cancer Treatment in Silico

Countless medical researchers over the past century have been occupied by the search for a cure of cancer. So far, they have developed and implemented a wide range of treatment techniques, including surgery, chemo- and radiotherapy, antiangiogenic drugs, small molecule inhibitors, and oncolytic viruses. However, patterns of these treatments' effectiveness remain largely unclear, and a better understanding of how cancer therapies work has become a key research goal. Cancer Treatment in Silico provides the first in-depth study of approaching this

Concepts and Experimental Protocols of Modelling and Informatics in Drug Design

Concepts and Experimental Protocols of Modelling and Informatics in Drug Design
  • Author : Om Silakari,Pankaj Kumar Singh
  • Publisher : Academic Press
  • Release : 05 November 2020
GET THIS BOOKConcepts and Experimental Protocols of Modelling and Informatics in Drug Design

Concepts and Experimental Protocols of Modelling and Informatics in Drug Design discusses each experimental protocol utilized in the field of bioinformatics, focusing especially on computer modeling for drug development. It helps the user in understanding the field of computer-aided molecular modeling (CAMM) by presenting solved exercises and examples. The book discusses topics such as fundamentals of molecular modeling, QSAR model generation, protein databases and how to use them to select and analyze protein structure, and pharmacophore modeling for drug targets.

Fragment-Based Drug Discovery

Fragment-Based Drug Discovery
  • Author : Steven Howard,Chris Abell
  • Publisher : Royal Society of Chemistry
  • Release : 03 July 2015
GET THIS BOOKFragment-Based Drug Discovery

Fragment-based drug discovery is a rapidly evolving area of research, which has recently seen new applications in areas such as epigenetics, GPCRs and the identification of novel allosteric binding pockets. The first fragment-derived drug was recently approved for the treatment of melanoma. It is hoped that this approval is just the beginning of the many drugs yet to be discovered using this fascinating technique. This book is written from a Chemist's perspective and comprehensively assesses the impact of fragment-based drug

Annual Reports in Medicinal Chemistry

Annual Reports in Medicinal Chemistry
  • Author : Anonim
  • Publisher : Elsevier
  • Release : 13 September 2013
GET THIS BOOKAnnual Reports in Medicinal Chemistry

Annual Reports in Medicinal Chemistry provides timely and critical reviews of important topics in medicinal chemistry together with an emphasis on emerging topics in the biological sciences, which are expected to provide the basis for entirely new future therapies. Annual Reports in Medicinal Chemistry provides timely and critical reviews and this volume covers important topics such as drug Discovery, Idiopathic Pulmonary Fibrosis and Neuraminidase Inhibitors

Inhibitors of Molecular Chaperones as Therapeutic Agents

Inhibitors of Molecular Chaperones as Therapeutic Agents
  • Author : Timothy D. Machajewski,Zhenhai Gao,David P. Rotella
  • Publisher : Royal Society of Chemistry
  • Release : 23 May 2022
GET THIS BOOKInhibitors of Molecular Chaperones as Therapeutic Agents

This book aims to provide a comprehensive examination of the field of molecular chaperone inhibition and its application to pharmaceutical research. With several small molecule inhibitors in oncology clinical development, there is clearly intense interest in the chaperones as a molecular target. Filling a significant gap in the market by providing a detailed comparison of discovery programs across the industry, this text will find broad interest among researchers in the field of molecular chaperone pharmaceutical research, oncology research, and medicinal

Towards Efficient Designing of Safe Nanomaterials

Towards Efficient Designing of Safe Nanomaterials
  • Author : Jerzy Leszczynski,Tomasz Puzyn
  • Publisher : Royal Society of Chemistry
  • Release : 30 September 2012
GET THIS BOOKTowards Efficient Designing of Safe Nanomaterials

The expanding field of nanotechnology is now one of the most promising areas of science. However, because some nanoparticles can have a negative impact on human health and the environment, the design of novel materials must always be accompanied by a comprehensive risk assessment. Until now, the information on the methods available has been fragmented and incomplete. This book is the first to provide a comprehensive review of recent progress and challenges in the risk assessment of nanomaterials by empirical

Quantitative Structure-Activity Relationships in Drug Design, Predictive Toxicology, and Risk Assessment

Quantitative Structure-Activity Relationships in Drug Design, Predictive Toxicology, and Risk Assessment
  • Author : Roy, Kunal
  • Publisher : IGI Global
  • Release : 28 February 2015
GET THIS BOOKQuantitative Structure-Activity Relationships in Drug Design, Predictive Toxicology, and Risk Assessment

Quantitative structure-activity relationships (QSARs) represent predictive models derived from the application of statistical tools correlating biological activity or other properties of chemicals with descriptors representative of molecular structure and/or property. Quantitative Structure-Activity Relationships in Drug Design, Predictive Toxicology, and Risk Assessment discusses recent advancements in the field of QSARs with special reference to their application in drug development, predictive toxicology, and chemical risk analysis. Focusing on emerging research in the field, this book is an ideal reference source for