Epigenetics and Regeneration

Epigenetics and Regeneration compiles the first foundational reference on epigenetic mechanisms governing tissue development, repair, homeostasis, and regeneration, as well as pathways to employ these mechanisms in clinical practice and translational science. In this book, life science researchers, clinicians, and students will discover an interdisciplinary resource bringing together common themes in the field, background overviews, research methods, recent advances, and opportunities for drug discovery. Throughout this volume, special attention is paid to pre-clinical and first clinical studies aimed at increasing the regenerative potential of damaged tissues by epigenetic drugs, as well as innovative, discipline spanning strategies to enhance cell reprogramming. As an all-inclusive, evidence-based volume, Epigenetics and Regeneration will stimulate discussion and boost new research in this fascinating and impactful area of translational epigenetics. Provides a foundational overview of epigenetics in regenerative medicine Examines epigenetic components of tissue regeneration for a variety of organ systems and tissue types, as well as current attempts to employ these mechanisms in clinical practice Offers researchers, students, clinicians, and pharmacologists the tools they need to enhance tissue development, repair, homeostasis, and regeneration and explore new epigenetic therapeutic pathways Features chapter contributions from leading international researchers and clinicians in the fields of epigenetics and regenerative medicine

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  • Author : Anonim
  • Publisher : Academic Press
  • Pages : 541 pages
  • ISBN : 0128148802
  • Rating : 4/5 from 21 reviews
CLICK HERE TO GET THIS BOOKEpigenetics and Regeneration

Epigenetics and Regeneration

Epigenetics and Regeneration
  • Author : Anonim
  • Publisher : Academic Press
  • Release : 24 May 2019
GET THIS BOOKEpigenetics and Regeneration

Epigenetics and Regeneration compiles the first foundational reference on epigenetic mechanisms governing tissue development, repair, homeostasis, and regeneration, as well as pathways to employ these mechanisms in clinical practice and translational science. In this book, life science researchers, clinicians, and students will discover an interdisciplinary resource bringing together common themes in the field, background overviews, research methods, recent advances, and opportunities for drug discovery. Throughout this volume, special attention is paid to pre-clinical and first clinical studies aimed at increasing

Epigenetic Regulation of Skin Development and Regeneration

Epigenetic Regulation of Skin Development and Regeneration
  • Author : Vladimir A. Botchkarev,Sarah E. Millar
  • Publisher : Springer
  • Release : 03 September 2018
GET THIS BOOKEpigenetic Regulation of Skin Development and Regeneration

This indispensable volume highlights recent studies identifying epigenetic mechanisms as essential regulators of skin development, stem cell activity and regeneration. Chapters are contributed by leading experts and promote the skin as an accessible model system for studying mechanisms that control organ development and regeneration. The timely discussions contained throughout are of broad relevance to other areas of biology and medicine and can help inform the development of novel therapeutics for skin disorders as well as new approaches to skin regeneration

Stem Cell Epigenetics

Stem Cell Epigenetics
  • Author : Anonim
  • Publisher : Academic Press
  • Release : 14 August 2020
GET THIS BOOKStem Cell Epigenetics

Stem Cell Epigenetics, Volume 16, examines how epigenetics are involved in stem cell differentiation, how a stem cell rapidly transitions into a molecularly distinct cell type, and how this process may be reversed or managed via epigenetic reprogramming. Topics discussed include chromatin in pluripotency, epigenetic regulation of reprogramming, stem cells and DNA methylation, histone modifications in stem cells and differentiation, higher-order chromatin conformation in pluripotent cells, epigenetics and disease modeling, organoids from pluripotent cells, transcriptional regulation in stem cells and differentiation,

Introduction to Epigenetics

Introduction to Epigenetics
  • Author : Renato Paro,Ueli Grossniklaus,Raffaella Santoro,Anton Wutz
  • Publisher : Springer Nature
  • Release : 23 March 2021
GET THIS BOOKIntroduction to Epigenetics

This open access textbook leads the reader from basic concepts of chromatin structure and function and RNA mechanisms to the understanding of epigenetics, imprinting, regeneration and reprogramming. The textbook treats epigenetic phenomena in animals, as well as plants. Written by four internationally known experts and senior lecturers in this field, it provides a valuable tool for Master- and PhD- students who need to comprehend the principles of epigenetics, or wish to gain a deeper knowledge in this field. After reading

Cartilage Tissue Engineering and Regeneration Techniques

Cartilage Tissue Engineering and Regeneration Techniques
  • Author : Dimitrios D. Nikolopoulos,George K. Safos,Kalpaxis Dimitrios
  • Publisher : BoD – Books on Demand
  • Release : 05 June 2019
GET THIS BOOKCartilage Tissue Engineering and Regeneration Techniques

Osteochondral defects can be challenging to treat, first, because the damaged articular cartilage has a poor intrinsic reparative capability, and second, because these defects cause chronic pain and serious disability. That is why cartilage repair remains one of the most challenging issues of musculoskeletal medicine. Arthroscopic and open techniques that have been developed over the last two decades intend to promote the success of complete repair of the articular cartilage defects; nevertheless, these therapies cannot always offer 100% success. Nowadays, cartilage

The Epigenetics Revolution

The Epigenetics Revolution
  • Author : Nessa Carey
  • Publisher : Columbia University Press
  • Release : 06 March 2012
GET THIS BOOKThe Epigenetics Revolution

Epigenetics can potentially revolutionize our understanding of the structure and behavior of biological life on Earth. It explains why mapping an organism's genetic code is not enough to determine how it develops or acts and shows how nurture combines with nature to engineer biological diversity. Surveying the twenty-year history of the field while also highlighting its latest findings and innovations, this volume provides a readily understandable introduction to the foundations of epigenetics. Nessa Carey, a leading epigenetics researcher, connects the

Epigenetics, Nuclear Organization & Gene Function

Epigenetics, Nuclear Organization & Gene Function
  • Author : John C. Lucchesi
  • Publisher : Oxford University Press
  • Release : 19 December 2018
GET THIS BOOKEpigenetics, Nuclear Organization & Gene Function

Epigenetics is the study of heritable changes in gene function that do not involve changes in the DNA sequence. These changes, consisting principally of DNA methylation, histone modifications, and non-coding RNAs, maintain or modulate the initial impact of regulatory factors that recognize and associate with particular genomic sequences. Epigenetic modifications are manifest in all aspects of normal cellular differentiation and function, but they can also have damaging effects that result in pathologies such as cancer. Research is continuously uncovering the

Chromatin and Epigenetics

Chromatin and Epigenetics
  • Author : Colin Logie,Tobias Aurelius Knoch
  • Publisher : BoD – Books on Demand
  • Release : 29 January 2020
GET THIS BOOKChromatin and Epigenetics

Genomics has gathered broad public attention since Lamarck put forward his top-down hypothesis of 'motivated change' in 1809 in his famous book "Philosophie Zoologique" and even more so since Darwin published his famous bottom-up theory of natural selection in "The Origin of Species" in 1859. The public awareness culminated in the much anticipated race to decipher the sequence of the human genome in 2002. Over all those years, it has become apparent that genomic DNA is compacted into chromatin with a dedicated 3D

Handbook of Epigenetics

Handbook of Epigenetics
  • Author : Trygve Tollefsbol
  • Publisher : Academic Press
  • Release : 10 July 2017
GET THIS BOOKHandbook of Epigenetics

Handbook of Epigenetics: The New Molecular and Medical Genetics, Second Edition, provides a comprehensive analysis of epigenetics, from basic biology, to clinical application. Epigenetics is considered by many to be the new genetics in that many biological phenomena are controlled, not through gene mutations, but rather through reversible and heritable epigenetic processes. These epigenetic processes range from DNA methylation to prions. The biological processes impacted by epigenetics are vast and encompass effects in lower organisms and humans that include tissue

Mechanisms of Regeneration

Mechanisms of Regeneration
  • Author : Anonim
  • Publisher : Academic Press
  • Release : 07 February 2014
GET THIS BOOKMechanisms of Regeneration

This new volume of Current Topics in Developmental Biology covers the area of mechanisms in regeneration. With an international board of authors, it provides a comprehensive set of reviews covering such topics as control of growth during regeneration, skeletal muscle degeneration and regeneration in mammals and flies, and suppression of regeneration in mammals. Covers the area of mechanisms in regeneration International board of authors Provides a comprehensive set of reviews

Kidney Development, Disease, Repair and Regeneration

Kidney Development, Disease, Repair and Regeneration
  • Author : Melissa Helen Little
  • Publisher : Academic Press
  • Release : 06 August 2015
GET THIS BOOKKidney Development, Disease, Repair and Regeneration

Kidney Development, Disease, Repair and Regeneration focuses on the molecular and cellular basis of kidney development, exploring the origins of kidney lineages, the development of kidney tissue subcompartments, as well as the genetic and environmental regulation of kidney development. Special coverage is given to kidney stem cells and possible steps towards kidney repair and regeneration. Emphasis is placed on the fetal origins of postnatal renal disease and our current understanding of the molecular basis of damage and repair. Biomedical researchers

Epigenetics of Aging

Epigenetics of Aging
  • Author : Trygve O. Tollefsbol
  • Publisher : Springer Science & Business Media
  • Release : 11 November 2009
GET THIS BOOKEpigenetics of Aging

Recent studies have indicated that epigenetic processes may play a major role in both cellular and organismal aging. These epigenetic processes include not only DNA methylation and histone modifications, but also extend to many other epigenetic mediators such as the polycomb group proteins, chromosomal position effects, and noncoding RNA. The topics of this book range from fundamental changes in DNA methylation in aging to the most recent research on intervention into epigenetic modifications to modulate the aging process. The major

Medical Epigenetics

Medical Epigenetics
  • Author : Anonim
  • Publisher : Academic Press
  • Release : 27 August 2021
GET THIS BOOKMedical Epigenetics

Medical Epigenetics, Second Edition provides a comprehensive analysis of epigenetics in health management, across a broad spectrum of disease categories and specialties, and with a focus on human systems, epigenetic diseases that affect these systems, and evolving modes of epigenetic-based treatment. Here, more than 40 leading researchers examine how each human system is affected by epigenetic maladies, offering an all-in-one resource on medical epigenetics not only for those directly involved with health care, but investigators in life sciences, biotech companies, graduate

Principles of Regenerative Medicine

Principles of Regenerative Medicine
  • Author : Anthony Atala,Robert Lanza,James A. Thomson,Robert Nerem
  • Publisher : Academic Press
  • Release : 16 December 2010
GET THIS BOOKPrinciples of Regenerative Medicine

Virtually any disease that results from malfunctioning, damaged, or failing tissues may be potentially cured through regenerative medicine therapies, by either regenerating the damaged tissues in vivo, or by growing the tissues and organs in vitro and implanting them into the patient. Principles of Regenerative Medicine discusses the latest advances in technology and medicine for replacing tissues and organs damaged by disease and of developing therapies for previously untreatable conditions, such as diabetes, heart disease, liver disease, and renal failure.

Epigenetic Gene Expression and Regulation

Epigenetic Gene Expression and Regulation
  • Author : Suming Huang,Michael D Litt,C. Ann Blakey
  • Publisher : Academic Press
  • Release : 19 October 2015
GET THIS BOOKEpigenetic Gene Expression and Regulation

Epigenetic Gene Expression and Regulation reviews current knowledge on the heritable molecular mechanisms that regulate gene expression, contribute to disease susceptibility, and point to potential treatment in future therapies. The book shows how these heritable mechanisms allow individual cells to establish stable and unique patterns of gene expression that can be passed through cell divisions without DNA mutations, thereby establishing how different heritable patterns of gene regulation control cell differentiation and organogenesis, resulting in a distinct human organism with a