Essentials of Noncoding RNA in Neuroscience

Essentials of Noncoding RNA in Neuroscience: Ontogenetics, Plasticity of the Vertebrate Brain focuses on the role of miRNAs in neurogenesis, gliogenesis, neuronal network formation, and the cell biology of forebrain development. The important role miRNAs play in neuronal maturation, neocortex function, and in some neurodevelopmental disorders is discussed, as are the computational challenges and methods used in the identification of miRNA targets. This book is a valuable reference for neuroscientists who wish to better understand the role of miRNAs in complex processes. It is of strong interest to those working to develop enabling technologies to detect and monitor miRNA expression and function, and to evaluate its roles in neural progenitor proliferation/differentiation, neuronal plasticity, and learning and memory. Discusses the unique features of neural miRNAs Details functional investigation of miRNA actions and current experimental approaches Includes extensive coverage of miRNA biology, developmental and postnatal neurogenesis, and computational challenges for miRNA target identification Contains thorough discussion of the transcriptional control of miRNA expression in forebrain development and in specific neuronal subtypes, as well as miRNA function in neurogenesis, neuronal network maturation, plasticity, gliogenesis, and dysfunction Provides an overview of miRNA roles in neurodevelopmental disorders and their possible role in the evolution of the neocortex

Produk Detail:

  • Author : Davide De Pietri Tonelli
  • Publisher : Academic Press
  • Pages : 338 pages
  • ISBN : 0128498994
  • Rating : 4/5 from 21 reviews
CLICK HERE TO GET THIS BOOKEssentials of Noncoding RNA in Neuroscience

Essentials of Noncoding RNA in Neuroscience

Essentials of Noncoding RNA in Neuroscience
  • Author : Davide De Pietri Tonelli
  • Publisher : Academic Press
  • Release : 14 June 2017
GET THIS BOOKEssentials of Noncoding RNA in Neuroscience

Essentials of Noncoding RNA in Neuroscience: Ontogenetics, Plasticity of the Vertebrate Brain focuses on the role of miRNAs in neurogenesis, gliogenesis, neuronal network formation, and the cell biology of forebrain development. The important role miRNAs play in neuronal maturation, neocortex function, and in some neurodevelopmental disorders is discussed, as are the computational challenges and methods used in the identification of miRNA targets. This book is a valuable reference for neuroscientists who wish to better understand the role of miRNAs in

Small Non-Coding RNAs

Small Non-Coding RNAs
  • Author : Mathieu Rederstorff
  • Publisher : Humana Press
  • Release : 21 March 2015
GET THIS BOOKSmall Non-Coding RNAs

This volume contains state-of-the-art methods tackling all aspects of small non-coding RNAs biology. Small Non-Coding RNAs: Methods and Protocols guides readers through customized dedicated protocols and technologies that will be of valuable help to all those willing to contribute deciphering the numerous functions of small non-coding RNAs. Written in the highly successful Methods of Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols and key tips

Neurotrophic Factors

Neurotrophic Factors
  • Author : Gary R. Lewin,Bruce D. Carter
  • Publisher : Springer Science & Business Media
  • Release : 25 March 2014
GET THIS BOOKNeurotrophic Factors

This book provides critical reviews of the role of neurotrophins and their receptors in a wide variety of diseases including neurodegenerative diseases like Huntington’s syndrome, cognitive function, psychiatric disorders such as clinical depression, Rett syndrome, motoneurone disease, spinal cord injury, pain, metabolic disease and cardiovascular disease. It also contains contributions from leaders in the field dealing with the basic biology, transcriptional and post-translational regulation of the neurotrophins and their receptors. The present book will review all recent areas of

Long Noncoding RNAs in Plants

Long Noncoding RNAs in Plants
  • Author : Santosh Kumar Upadhyay
  • Publisher : Academic Press
  • Release : 13 November 2020
GET THIS BOOKLong Noncoding RNAs in Plants

The growth of human population has increased the demand for improved yield and quality of crops and horticultural plants. However, plant productivity continues to be threatened by stresses such as heat, cold, drought, heavy metals, UV radiations, bacterial and fungal pathogens, and insect pests. Long noncoding RNAs are associated with various developmental pathways, regulatory systems, abiotic and biotic stress responses and signaling, and can provide an alternative strategy for stress management in plants. Long Noncoding RNAs in Plants: Roles in

RNA Metabolism in Neurodegenerative Diseases

RNA Metabolism in Neurodegenerative Diseases
  • Author : Rita Sattler,Christopher J. Donnelly
  • Publisher : Springer
  • Release : 18 June 2018
GET THIS BOOKRNA Metabolism in Neurodegenerative Diseases

It has become evident over the last years that abnormalities in RNA processing play a fundamental part in the pathogenesis of neurodegenerative diseases. Cellular viability depends on proper regulation of RNA metabolism and subsequent protein synthesis, which requires the interplay of many processes including transcription, pre--‐mRNA splicing, mRNA editing as well as mRNA stability, transport and translation. Dysfunction in any of these processes, often caused by mutations in the coding and non--‐ coding RNAs, can be very destructive to

The Epstein-Barr Virus

The Epstein-Barr Virus
  • Author : M. A. Epstein,B. G. Achong
  • Publisher : Springer Science & Business Media
  • Release : 06 December 2012
GET THIS BOOKThe Epstein-Barr Virus

The Epstein-Barr virus was discovered 15 years ago. Since that time an immense body of information has been accumu lated on this agent which has come to assume great signifi cance in many different fields of biological science. Thus, the virus has very special relevance in human medicine and oncology, in tumor virology, in immunology, and in mole cular virology, since it is the cause of infectious mononu cleosis and also the first human cancer virus, etiologically related to endemic Burkitt's

Amyotrophic Lateral Sclerosis

Amyotrophic Lateral Sclerosis
  • Author : Muralidhar L. Hegde
  • Publisher : BoD – Books on Demand
  • Release : 26 August 2020
GET THIS BOOKAmyotrophic Lateral Sclerosis

A flurry of recent research on the role of the RNA/DNA-binding proteins TDP-43 and FUS as well as a dozen other factors (e.g., C9ORF72 and profilin) has led to a new paradigm in our understanding of the pathobiology of the motor neuron disease, Amyotrophic Lateral Sclerosis (ALS). How these factors trigger neuromuscular dysfunction is critical for developing more effective ALS therapeutics. The ‘gain-of-toxicity’ or ‘loss-of-function’ of these etiological factors is a key question. Recent studies on the

Epigenetics of Chronic Pain

Epigenetics of Chronic Pain
  • Author : Anonim
  • Publisher : Academic Press
  • Release : 29 October 2018
GET THIS BOOKEpigenetics of Chronic Pain

Epigenetics of Chronic Pain, Volume Nine, presents comprehensive information on the role of epigenetics in chronic pain sensitivity, providing a detailed, but accessible, view of the field from basic principles, to clinical application. Leading international researchers discuss essential mechanisms of chronic pain epigenetics, including the molecular processes of chromatin remodeling, histone modifications, and the microRNAs and noncoding RNAs involved in regulating genes tied to pain sensitivity. The influence of epigenetics in inflammatory, neuropathic, visceral and other pain models is examined,

Non-coding RNA and the Reproductive System

Non-coding RNA and the Reproductive System
  • Author : Dagmar Wilhelm,Pascal Bernard
  • Publisher : Springer
  • Release : 11 December 2015
GET THIS BOOKNon-coding RNA and the Reproductive System

This book provides an overview of the role and function of regulatory RNAs that lack protein-coding potential in key reproductive tissues. This includes the role of small interfering RNAs (siRNAs), microRNAs (miRNAs), PIWI-interacting RNAs (piRNAs), small nucleolar RNAs (snoRNAs) and long non-coding RNAs (lncRNAs). Through clear, detailed and comprehensive debate, international leading experts discuss the role these novel regulators in normal development of sexual dimorphisms, including the differentiation of ovaries and testes, the genital tract including prostate, epididymis and uterus,

MicroRNA in Regenerative Medicine

MicroRNA in Regenerative Medicine
  • Author : Chandan K. Sen
  • Publisher : Elsevier
  • Release : 26 November 2014
GET THIS BOOKMicroRNA in Regenerative Medicine

This work encapsulates the uses of miRNA across stem cells, developmental biology, tissue injury and tissue regeneration. In particular contributors provide focused coverage of methodologies, intervention and tissue engineering. Regulating virtually all biological processes, the genome’s 1048 encoded microRNAs appear to hold considerable promise for the potential repair and regeneration of tissues and organs in future therapies. In this work, 50 experts address key topics of this fast-emerging field. Concisely summarizing and evaluating key findings emerging from fundamental research into translational

Long Non Coding RNA Biology

Long Non Coding RNA Biology
  • Author : M.R.S. Rao
  • Publisher : Springer
  • Release : 16 August 2017
GET THIS BOOKLong Non Coding RNA Biology

This contributed volume offers a comprehensive and detailed overview of the various aspects of long non-coding RNAs and discusses their emerging significance. Written by leading experts in the field, it motivates young researchers around the globe, and offers graduate and postgraduate students fascinating insights into genes and their regulation in eukaryotes and higher organisms.