Fluorine and Health

Fluorine and Health presents a critical multidisciplinary overview on the contribution of fluorinated compounds to resolve the important global issue of medicinal monitoring and health care. The involved subjects are organized in three thematic parts devoted to Molecular Imaging, Biomedical Materials and Pharmaceuticals. Initially the key-position of partially fluorinated low molecular weight compounds labelled either with the natural 19F-isotope for Magnetic Resonance Imaging (MRI) or labelled with the radioactive [18F]-isotope for Positron Emission Tomography (PET) is highlighted. Both non-invasive methods belong to the most challenging in vivo imaging techniques in oncology, neurology and in cardiology for the diagnosis of diseases having the highest mortality in the industrialized countries. The manifold facets of fluorinated biomaterials range from inorganic ceramics to perfluorinated organic molecules. Liquid perfluorocarbons are suitable for oxygen transport and as potential respiratory gas carriers, while fluorinated polymers are connected to the pathology of blood vessels. Another important issue concerns the application of highly fluorinated liquids in ophthalmology. Moreover, fluorine is an essential trace element in bone mineral, dentine and tooth enamel and is applied for the prophylaxis and treatment of dental caries. The various origins of human exposure to fluoride species is detailed to promote a better understanding of the effect of fluoride species on living organisms. Medicinally relevant fluorinated molecules and their interactions with native proteins are the main focus of the third part. New molecules fluorinated in strategic position are crucial for the development of pharmaceuticals with desired action and optimal pharmacological profile. Among the hundreds of marketed active drug components there are more than 150 fluorinated compounds. The chapters will illustrate how the presence of fluorine atoms alters properties of bioactive compounds at various biochemical steps, and possibly facilitate its emergence as pharmaceuticals. Finally the synthetic potential of a fluorinase, the first C-F bond forming enzyme, is summarized. - New approach of topics involving chemistry, biology and medicinal techniques - Transdisciplinar papers on fluoride products - Importance of fluoride products in health - Updated data on specific topics

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  • Author : Alain Tressaud
  • Publisher : Elsevier
  • Pages : 816 pages
  • ISBN : 9780080558110
  • Rating : 4/5 from 21 reviews
CLICK HERE TO GET THIS BOOKFluorine and Health

Fluorine and Health

Fluorine and Health
  • Author : Alain Tressaud,Gunter Haufe
  • Publisher : Elsevier
  • Release : 06 June 2008
GET THIS BOOKFluorine and Health

Fluorine and Health presents a critical multidisciplinary overview on the contribution of fluorinated compounds to resolve the important global issue of medicinal monitoring and health care. The involved subjects are organized in three thematic parts devoted to Molecular Imaging, Biomedical Materials and Pharmaceuticals. Initially the key-position of partially fluorinated low molecular weight compounds labelled either with the natural 19F-isotope for Magnetic Resonance Imaging (MRI) or labelled with the radioactive [18F]-isotope for Positron Emission Tomography (PET) is highlighted. Both non-invasive

Toxicological Profile for Fluorides, Hydrogen Fluoride, and Fluorine (Update)

Toxicological Profile for Fluorides, Hydrogen Fluoride, and Fluorine (Update)
  • Author : Carolyn A. Tylenda
  • Publisher : DIANE Publishing
  • Release : 01 May 2011
GET THIS BOOKToxicological Profile for Fluorides, Hydrogen Fluoride, and Fluorine (Update)

This toxicological profile succinctly characterizes the toxicologic and adverse health effects information for fluorides, hydrogen fluoride, and fluorine. Fluorides are often added to drinking water supplies and a variety of dental compounds. Some fluoride compounds are also used in the production of glass and enamel and in the steel industry. Fluorine gas is used primarily to make chemical compounds used in separating isotopes of uranium for use in nuclear reactors and nuclear weapons. Hydrogen fluoride is used in the manufacture

Fluorine

Fluorine
  • Author : Professor Victor Preedy
  • Publisher : Royal Society of Chemistry
  • Release : 29 April 2015
GET THIS BOOKFluorine

Fluorine is best known for its role in the prevention of cavities and in improving oral and bone health however equally there are millions of people around the world suffering from dental fluorosis due to chronic exposure to high levels of fluoride in drinking water. This volume, written by leading researchers in this area, examines the positives and negatives of fluorine and its effects on humans for example fluoride-induced oxidative stress in the liver, effects of fluoride on insulin and

Fluorine Chemistry

Fluorine Chemistry
  • Author : J.H. Simons
  • Publisher : Elsevier
  • Release : 02 December 2012
GET THIS BOOKFluorine Chemistry

Fluorine Chemistry, Volume IV provides an extensive survey and discussion on the physiological properties of fluoride ion and substances capable of producing it in aqueous solution. This book elaborates the detrimental effects of excessive fluoride ingestion, through the beneficial effects of optimal amounts, to recognized detrimental effects, such as dental caries accompanied by suboptimal fluoride intake. Fluoride metabolism is discussed in detail, including the capacity for storage of fluoride by the bones and rates of excretion of fluoride from the

Toxicological Profile for Fluorides, Hydrogen Fluoride and Fluorine (F)

Toxicological Profile for Fluorides, Hydrogen Fluoride and Fluorine (F)
  • Author : U.S. DEPARTMENT OF HEALTH AND HUMAN SERVICES
  • Publisher : DIANE Publishing
  • Release : 28 October 2021
GET THIS BOOKToxicological Profile for Fluorides, Hydrogen Fluoride and Fluorine (F)

Provides info. about fluorine, hydrogen fluoride, & fluorides, & the human health effects of exposure. These chemicals have been found in many sites identified by the EPA for long-term Federal cleanup activities. Includes a Public Health Statement which explains toxicologic properties of fluorine, hydrogen fluoride, & fluorides in a nontechnical, Q&A format, & a review of the general health effects observed following exposure; a description of health effects; how the chemical can affect children; & info. on their chemical & physical properties, production, use & disposal,

Fluoride in Drinking Water

Fluoride in Drinking Water
  • Author : National Research Council,Division on Earth and Life Studies,Board on Environmental Studies and Toxicology,Committee on Fluoride in Drinking Water
  • Publisher : National Academies Press
  • Release : 22 January 2007
GET THIS BOOKFluoride in Drinking Water

Most people associate fluoride with the practice of intentionally adding fluoride to public drinking water supplies for the prevention of tooth decay. However, fluoride can also enter public water systems from natural sources, including runoff from the weathering of fluoride-containing rocks and soils and leaching from soil into groundwater. Fluoride pollution from various industrial emissions can also contaminate water supplies. In a few areas of the United States fluoride concentrations in water are much higher than normal, mostly from natural

Fluoride in Drinking-water

Fluoride in Drinking-water
  • Author : John Kirtley Fawell,Kenneth Bailey,World Health Organization,J. Chilton,E. Dahi
  • Publisher : World Health Organization
  • Release : 28 October 2021
GET THIS BOOKFluoride in Drinking-water

Fluoride is known to occur at elevated concentration in a number of parts of the world, where it can be a significant cause of disease. The primary focus of this book is the prevention of adverse health effects from excessive levels of fluoride in drinking water. The book fills the urgent need, identified for updating the WHO Guidelines for Drinking-water Quality, for information on the occurrence of fluoride, its health effects, ways of reducing excess levels, and methods for analysis

Fluoridation Facts

Fluoridation Facts
  • Author : American Dental Association
  • Publisher : American Dental Association
  • Release : 05 March 2018
GET THIS BOOKFluoridation Facts

All-in-one resource in for everything related to fluoridated water, from its impact on dental health to its safety and cost-effectiveness. Dispelling common myths that fluoridation is dangerous, this book provides science-backed information based on the most current research in Q&A format. This is the most in-depth and up-to-date educational resource available regarding fluoridated water, from the American Dental Association.