Freeze Drying of Pharmaceutical and Food Products

Freeze-drying is an important preservation technique for heat-sensitive pharmaceuticals and foods. Products are first frozen, then dried in a vacuum at low temperature by sublimation and desorption, rather than by the application of heat. The resulting items can be stored at room temperature for long periods. This informative text addresses both principles and practice in this area. The first chapter introduces freeze-drying. The authors then review the fundamentals of the technique, heat-mass transfer analyses, modelling of the drying process and the equipment employed. Further chapters focus on freeze-drying of food, freeze-drying of pharmaceuticals and the protective agents and additives applied. The final chapter covers the important subjects of disinfection, sterilization and process validation. Freeze-drying of pharmaceutical and food products is an essential reference for food, pharmaceutical and refrigeration engineers and scientists with an interest in preservation techniques. It will also be of use to students in these fields. Addresses the principles and practices used in this important preservation technique Explains the fundamentals of heat-mass transfer analysis, modelling and the equipment used Discusses the importance of disinfection, sterilization and process validation

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  • Author : Tse-Chao Hua
  • Publisher : Elsevier
  • Pages : 280 pages
  • ISBN : 1845697472
  • Rating : 4/5 from 21 reviews
CLICK HERE TO GET THIS BOOKFreeze Drying of Pharmaceutical and Food Products

Freeze-Drying of Pharmaceutical and Food Products

Freeze-Drying of Pharmaceutical and Food Products
  • Author : Tse-Chao Hua,Bao-Lin Liu,Haimei Zhang
  • Publisher : Elsevier
  • Release : 30 July 2010
GET THIS BOOKFreeze-Drying of Pharmaceutical and Food Products

Freeze-drying is an important preservation technique for heat-sensitive pharmaceuticals and foods. Products are first frozen, then dried in a vacuum at low temperature by sublimation and desorption, rather than by the application of heat. The resulting items can be stored at room temperature for long periods. This informative text addresses both principles and practice in this area. The first chapter introduces freeze-drying. The authors then review the fundamentals of the technique, heat-mass transfer analyses, modelling of the drying process and

Freeze Drying of Pharmaceutical Products

Freeze Drying of Pharmaceutical Products
  • Author : Davide Fissore,Roberto Pisano,Antonello Barresi
  • Publisher : CRC Press
  • Release : 24 October 2019
GET THIS BOOKFreeze Drying of Pharmaceutical Products

Freeze Drying of Pharmaceutical Products provides an overview of the most recent and cutting-edge developments and technologies in the field, focusing on formulation developments and process monitoring and considering new technologies for process development. This book contains case studies from freeze dryer manufacturers and pharmaceutical companies for readers in industry and academia. It was contributed to by lyophilization experts to create a detailed analysis of the subject matter, organically presenting recent advancements in freeze-drying research and technology. It discusses formulation

Freeze-Drying/Lyophilization Of Pharmaceutical & Biological Products, Second Edition, Revised and Expanded

Freeze-Drying/Lyophilization Of Pharmaceutical & Biological Products, Second Edition, Revised and Expanded
  • Author : Louis Rey,Joan C. May
  • Publisher : CRC Press
  • Release : 21 January 2004
GET THIS BOOKFreeze-Drying/Lyophilization Of Pharmaceutical & Biological Products, Second Edition, Revised and Expanded

Thoroughly acquainting the reader with freeze-drying fundamentals, Freeze-Drying/Lyophilization of Pharmaceutical and Biological Products, Second Edition carves practical guidelines from the very latest theoretical research, technologies, and industrial procedures. It delineates the best execution of steps from closure preparation and regulatory control of products to equipment sterilization and process validation. With 13 new chapters providing state-of-the-art information, the book unveils innovations currently advancing the field, including LYOGUARD® packaging for bulk freeze-drying and the irradiation of pharmaceutical and biological products.

Freeze-Drying

Freeze-Drying
  • Author : Georg-Wilhelm Oetjen,Peter Haseley
  • Publisher : John Wiley & Sons
  • Release : 08 January 2008
GET THIS BOOKFreeze-Drying

Many modern pharmaceutical and biological products, e.g. blood derivatives, vaccines, cytostatic drugs, antibiotics, bacteria cultures but also consumer goods such as soluble coffee are freeze-dried to transform perishable substances into a form that can be stored and reconstituted to their almost original state without loss of quality. The book describes the up-to-date fundamentals of freeze-drying, not just presenting the process in all its seven steps theoretically, but explaining it with many practical examples. Many years of experience in freeze-drying

Freeze-Drying/Lyophilization of Pharmaceutical and Biological Products

Freeze-Drying/Lyophilization of Pharmaceutical and Biological Products
  • Author : Louis Rey
  • Publisher : CRC Press
  • Release : 19 April 2016
GET THIS BOOKFreeze-Drying/Lyophilization of Pharmaceutical and Biological Products

Freeze-drying, or lyophilization, is a well established technology used in the preservation of numerous pharmaceutical and biological products. This highly effective dehydration method involves the removal of water from frozen materials via the direct sublimation of ice. In recent years, this process has met with many changes, as have the regulatio

Drying Technologies for Biotechnology and Pharmaceutical Applications

Drying Technologies for Biotechnology and Pharmaceutical Applications
  • Author : Satoshi Ohtake,Ken-ichi Izutsu,David Lechuga-Ballesteros
  • Publisher : John Wiley & Sons
  • Release : 03 February 2020
GET THIS BOOKDrying Technologies for Biotechnology and Pharmaceutical Applications

A comprehensive source of information about modern drying technologies that uniquely focus on the processing of pharmaceuticals and biologicals Drying technologies are an indispensable production step in the pharmaceutical industry and the knowledge of drying technologies and applications is absolutely essential for current drug product development. This book focuses on the application of various drying technologies to the processing of pharmaceuticals and biologicals. It offers a complete overview of innovative as well as standard drying technologies, and addresses the issues

Fundamentals of Freeze-drying

Fundamentals of Freeze-drying
  • Author : J. D. Mellor
  • Publisher : Unknown Publisher
  • Release : 01 March 1978
GET THIS BOOKFundamentals of Freeze-drying

Classical theory of sublimation. Heat transfer. Vapour transfer. Drying rate. Physical mechanism of cyclic-pressure freeze-drying. Analytical cyclic process. Drying plant and equipment. Laboratory apparatus and techniques. Drying plant and equipment for freeze-drying. foodstuffs. Effects of freeze-drying. Miscellaneous aspects of freeze-drying. Biological aspects.

Good Pharmaceutical Freeze-Drying Practice

Good Pharmaceutical Freeze-Drying Practice
  • Author : Peter Cameron
  • Publisher : CRC Press
  • Release : 30 June 1997
GET THIS BOOKGood Pharmaceutical Freeze-Drying Practice

This text is devoted to pharmaceutical freeze-drying in all its forms and in all its technological variations. Whether you freeze-dry nonsterile tablets or you lyophilize injectables, this book covers all the technological and regulatory requirements. Written by a panel of leading practitioners in the pharmaceutical industry -- production experts, regulatory inspectors, technical consultants, and equipment suppliers -- the information is relevant, usable, and timely. Practical, "how to" chapters serve as training aids, and each section stands on its own as

Lyophilization of Pharmaceuticals and Biologicals

Lyophilization of Pharmaceuticals and Biologicals
  • Author : Kevin R. Ward,Paul Matejtschuk
  • Publisher : Humana Press
  • Release : 13 December 2018
GET THIS BOOKLyophilization of Pharmaceuticals and Biologicals

This detailed volume brings together leading practitioners in the freeze-drying community to address recent progress, not only in new analytical tools and applications of the data derived in cycle design but also in the manufacturing of lyophilized products in the healthcare sector – whether these be therapeutics, vaccines or diagnostic products - and indeed the equipment to deliver this scale of freeze-drying. Areas of focus include analytical and formulation issues, process monitoring and control, as well as post-lyophilization analysis. Written for

Water Properties of Food, Pharmaceutical, and Biological Materials

Water Properties of Food, Pharmaceutical, and Biological Materials
  • Author : Maria del Pilar Buera,Jorge Welti-Chanes,Peter J. Lillford,Horacio R. Corti
  • Publisher : CRC Press
  • Release : 13 January 2006
GET THIS BOOKWater Properties of Food, Pharmaceutical, and Biological Materials

Unique and informative, Water Properties of Food, Pharmaceutical, and Biological Materials is based on lectures and papers given by leading international researchers at the 9th International Symposium of the Properties of Water in Foods (ISOPOW 9) that took place in September 2004. Each chapter presents an authoritative account of the latest research on the physical and chemical properties of water in relation to the stability of food, pharmaceutical, and biological materials. The first part of the text focuses on presentations given by

Delivery and Controlled Release of Bioactives in Foods and Nutraceuticals

Delivery and Controlled Release of Bioactives in Foods and Nutraceuticals
  • Author : Nissim Garti
  • Publisher : Elsevier
  • Release : 25 January 2008
GET THIS BOOKDelivery and Controlled Release of Bioactives in Foods and Nutraceuticals

Active ingredients in foods must remain fully functional for as long as necessary and be transported and discharged appropriately to have the desired nutritional effect. Delivery and controlled release systems are an essential way to achieve these aims. This important book reviews how to optimise these systems to maximise the health-promoting properties of food products. Opening chapters review factors affecting nutrient bioavailability and methods to test delivery system efficacy. Part two addresses materials used and specific techniques for delivery and