Gene Environment Interactions

Gene Environment Interactions: Nature and Nurture in the Twenty-first Century offers a rare, synergistic view of ongoing revelations in gene environment interaction studies, drawing together key themes from epigenetics, microbiomics, disease etiology, and toxicology to illuminate pathways for clinical translation and the paradigm shift towards precision medicine. Across eleven chapters, Dr. Smith discusses interactions with the environment, human adaptations to environmental stimuli, pathogen encounters across the centuries, epigenetic modulation of gene expression, transgenerational inheritance, the microbiome's intrinsic effects on human health, and the gene-environment etiology of cardiovascular, metabolic, psychiatric, behavioral and monogenic disorders. Later chapters illuminate how our new understanding of gene environment interactions are driving advances in precision medicine and novel treatments. In addition, the book's author shares strategies to support clinical translation of these scientific findings to improve heath literacy among the general population. Offers a thorough, interdisciplinary discussion on recent revelations from gene environment interaction studies Illuminates environmental factors affecting disease-gene etiology and treatment Supports the clinical translation of gene environment interaction findings into novel therapeutics and precision medicine

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  • Author : Moyra Smith
  • Publisher : Academic Press
  • Pages : 438 pages
  • ISBN : 0128196130
  • Rating : 4/5 from 21 reviews
CLICK HERE TO GET THIS BOOKGene Environment Interactions

Gene Environment Interactions

Gene Environment Interactions
  • Author : Moyra Smith
  • Publisher : Academic Press
  • Release : 24 January 2020
GET THIS BOOKGene Environment Interactions

Gene Environment Interactions: Nature and Nurture in the Twenty-first Century offers a rare, synergistic view of ongoing revelations in gene environment interaction studies, drawing together key themes from epigenetics, microbiomics, disease etiology, and toxicology to illuminate pathways for clinical translation and the paradigm shift towards precision medicine. Across eleven chapters, Dr. Smith discusses interactions with the environment, human adaptations to environmental stimuli, pathogen encounters across the centuries, epigenetic modulation of gene expression, transgenerational inheritance, the microbiome's intrinsic effects on human

Gene-Environment Interactions in Psychiatry

Gene-Environment Interactions in Psychiatry
  • Author : Bart Ellenbroek,Ji Un Youn
  • Publisher : Academic Press
  • Release : 26 July 2016
GET THIS BOOKGene-Environment Interactions in Psychiatry

Gene-Environment Interactions in Psychiatry: Nature, Nurture, Neuroscience begins with the basic aspects of gene–environment studies, such as basic genetics, principles of animals modeling, and the basic processes of how environmental factors affect brain and behavior, with part two describing the most important psychiatric disorders in detail. Each chapter has a similar structure that includes a general description of the disorder that is followed by an analysis of the role of genes and how they are affected by environmental factors.

Gene-Environment Interaction Analysis

Gene-Environment Interaction Analysis
  • Author : Sumiko Anno
  • Publisher : CRC Press
  • Release : 30 March 2016
GET THIS BOOKGene-Environment Interaction Analysis

Gene–environment (G × E) interaction analysis is a statistical method for clarifying G × E interactions applicable to a phenotype or a disease that is the result of interactions between genes and the environment. This book is the first to deal with the theme of G × E interaction analysis. It compiles and details cutting-edge research in bioinformatics and computational biology and will appeal to anyone involved in bioinformatics and computational biology.

Genotype by Environment Interaction

Genotype by Environment Interaction
  • Author : Manjit S. Kang,Hugh G. Gauch
  • Publisher : CRC-Press
  • Release : 06 February 1996
GET THIS BOOKGenotype by Environment Interaction

Genotype-by-Environment Interaction (GEI) is a prevalent issue among crop farmers, plant breeders, geneticists, and production agronomists. This book brings together contributions from expert plant breeders and quantitative geneticists to better understand the relationship between crop performance and environment. This information can reduce the cost of extensive genotype evaluation by eliminating unnecessary testing sites and by fine-tuning breeding programs. Molecular aspects of GEI are discussed for the first time and key bibliographical references on GEI are included in an appendix.

Gene-Environment Interactions

Gene-Environment Interactions
  • Author : Lucio G. Costa,David L. Eaton
  • Publisher : John Wiley & Sons
  • Release : 16 December 2005
GET THIS BOOKGene-Environment Interactions

Understanding the play between heredity and environment, andrelating it to disease causation, is the task of ecogenetics.Gene-Environment Interactions: Fundamentals of Ecogenetics presentsthe first comprehensive survey of this discipline, reflecting itsrelationship with toxicology, epidemiology, pharmacology, publichealth, and other medical and biological fields. Divided into four sections, the text elucidates key basic andadvanced topics: * Section 1 covers fundamentals, including the history of thediscipline, a discussion of the molecular laboratory toolscurrently available to assess genotypes, using such measurements inmolecular epidemiology studies, and the

Gene-environment Interactions and Human Diseases

Gene-environment Interactions and Human Diseases
  • Author : Lu Qi
  • Publisher : Unknown Publisher
  • Release : 01 December 2015
GET THIS BOOKGene-environment Interactions and Human Diseases

With tremendous success of genomic research in discovering genetic variations determining human diseases, it is now time to re-evaluate how the environment affects disease risk by taking into consideration these genetic findings. This book addresses a rapidly growing interest in assessing the relations between environmental risk factors (such as diet, lifestyle) and human diseases, by considering the potential roles of genomic make-up. The book brings together a selection of chapters written by specialists with a variety of backgrounds such as

Gene-Environment Interactions in Developmental Psychopathology

Gene-Environment Interactions in Developmental Psychopathology
  • Author : Kenneth A. Dodge,Michael Rutter
  • Publisher : Guilford Press
  • Release : 01 September 2011
GET THIS BOOKGene-Environment Interactions in Developmental Psychopathology

Bringing together foremost experts, this book reviews groundbreaking gene–environment research and explores implications for clinical practice, prevention, and public policy. Presented is cutting-edge work on the interplay of genetic factors and childhood experiences in the development of mental disorders such as depression, conduct disorder, and schizophrenia. Essential topics include what scientists currently know about "susceptibility genes"; the mechanisms by which maltreatment and other stressors interact with biological susceptibilities across development; and factors that make certain children more resilient than

Schizophrenia: A Consequence of Gene-Environment Interactions?

Schizophrenia: A Consequence of Gene-Environment Interactions?
  • Author : Tim Karl, Jonathon C. Arnold
  • Publisher : Frontiers Media SA
  • Release : 06 June 2015
GET THIS BOOKSchizophrenia: A Consequence of Gene-Environment Interactions?

Schizophrenia is a multi-factorial disease characterized by a high heritability and environmental risk factors (e.g. stress and cannabis use). In recent years, an increasing number of researchers worldwide have started investigating the ‘two-hit hypothesis’ of schizophrenia predicting that genetic and environmental risk factors interactively cause the development of the disorder. This work is starting to produce valuable new animal models and reveal novel insights into the pathophysiology of schizophrenia. Eventually, it might help advance studies of the molecular pathways

Beyond Our Genes

Beyond Our Genes
  • Author : Raffaele Teperino
  • Publisher : Springer Nature
  • Release : 24 January 2020
GET THIS BOOKBeyond Our Genes

The genotype/phenotype dichotomy is being slowly replaced by a more complex relationship whereby the majority of phenotypes arise from interactions between one’s genotype and the environment in which one lives. Interestingly, it seems that not only our lives, but also our ancestors’ lives, determine how we look. This newly recognized form of inheritance is known as (epi)genetic, as it involves an additional layer of information on top of the one encoded by the genes. Its discovery has

Gene-Environment Transactions in Developmental Psychopathology

Gene-Environment Transactions in Developmental Psychopathology
  • Author : Patrick H. Tolan,Bennett L. Leventhal
  • Publisher : Springer
  • Release : 30 March 2017
GET THIS BOOKGene-Environment Transactions in Developmental Psychopathology

This book examines the current research in gene-environment transactions (GEX) and its potential use in developing interventions and applications tailored to individual genetic makeups. Key concepts underlying GEX studies in this area are defined, identifying fundamental challenges in devising informed research questions and conducting valid and useful experiments. Chapters analyze GEX models inspired by the present day genome-based frameworks, particularly in terms of advances in identifying and understanding complex environmental factors, using examples from common psychological conditions, such as antisocial

Cancer and the Environment

Cancer and the Environment
  • Author : Institute of Medicine,Board on Health Sciences Policy,Roundtable on Environment Health Sciences, Research, and Medicine
  • Publisher : National Academies Press
  • Release : 01 September 2002
GET THIS BOOKCancer and the Environment

The Roundtable on Environmental Health Sciences, Research, and Medicine wanted to address the link between environmental factors and the development of cancer in light of recent advances in genomics. They asked what research tools are needed, how new scientific information can be applied in a timely manner to reduce the burden of cancer, and how this can be flexible enough to treat the individual.

The Recognition and Management of Early Psychosis

The Recognition and Management of Early Psychosis
  • Author : Patrick D. McGorry,Henry J. Jackson
  • Publisher : Cambridge University Press
  • Release : 28 July 1999
GET THIS BOOKThe Recognition and Management of Early Psychosis

The treatment of early psychosis has been bedevilled by an entrenched pessimism, stemming from the asylum era and the Kraepelinian model of schizophrenia. More recently, however, there has been a surge of interest in preventively oriented treatment of patients showing the first signs of psychotic illness, with the realization that these illnesses are frequently highly responsive to early treatment. This is the first text to focus on the potential of early detection of psychosis, and the practicalities of treatment. Based

Genetics, Environment, and Behavior

Genetics, Environment, and Behavior
  • Author : Lee Ehrman,Gilbert S. Omenn,Ernst Caspari
  • Publisher : Elsevier
  • Release : 17 September 2013
GET THIS BOOKGenetics, Environment, and Behavior

Genetics, Environment, and Behavior: Implications for Educational Policy is a collection of papers from the "Genetic Endowment and Environment in the Determination of Behavior" workshop in New York in October 1971. The book discusses the relationships between genetic characteristics and behavior as being significant in understanding human behavior and learning. The text also considers the different approaches made by geneticists and psychologists on this subject. Several papers review, in terms of both quantitative and qualitative analysis, the role that genetics and

Health Outcomes in a Foreign Land

Health Outcomes in a Foreign Land
  • Author : Bernard Kwabi-Addo
  • Publisher : Springer
  • Release : 15 July 2017
GET THIS BOOKHealth Outcomes in a Foreign Land

This stimulating volume uses multiple lenses to analyze the complex causes of health disparities affecting African Americans, and explains how this knowledge can be used to reduce their destructive effects. Pinpointing genetic, non-genetic, and epigenetic factors underlying health conditions common to the population—including heart disease, hypertension, diabetes, and cancer—the author traces intricate links among these factors in the current environmental and social context. The section on non-genetic factors in health disparities, such as social determinants and health behaviors,

Environmental Epigenetics

Environmental Epigenetics
  • Author : L. Joseph Su,Tung-chin Chiang
  • Publisher : Springer
  • Release : 18 May 2015
GET THIS BOOKEnvironmental Epigenetics

This book examines the toxicological and health implications of environmental epigenetics and provides knowledge through an interdisciplinary approach. Included in this volume are chapters outlining various environmental risk factors such as phthalates and dietary components, life states such as pregnancy and ageing, hormonal and metabolic considerations and specific disease risks such as cancer cardiovascular diseases and other non-communicable diseases. Environmental Epigenetics imparts integrative knowledge of the science of epigenetics and the issues raised in environmental epidemiology. This book is intended