Gene Therapy for Viral Infections

Gene Therapy for Viral Infections provides a comprehensive review of the broader field of nucleic acid and its use in treating viral infections. The text bridges the gap between basic science and important clinical applications of the technology, providing a systematic, integrated review of the advances in nucleic acid-based antiviral drugs and the potential advantages of new technologies over current treatment options. Coverage begins with the fundamentals, exploring varying topics, including harnessing RNAi to silence viral gene expression, antiviral gene editing, viral gene therapy vectors, and non-viral vectors. Subsequent sections include detailed coverage of the developing use of gene therapy for the treatment of specific infections, the principles of rational design of antivirals, and the hurdles that currently face the further advancement of gene therapy technology. Provides coverage of gene therapy for a variety of infections, including HBV, HCV, HIV, hemorrhagic fever viruses, and respiratory and other viral infections Bridges the gap between the basic science and the important medical applications of this technology Features a broad approach to the topic, including an essential overview and the applications of gene therapy, synthetic RNA, and other antiviral strategies that involve nucleic acid engineering Presents perspectives on the future use of nucleic acids as a novel class of antiviral drugs Arms the reader with the cutting-edge information needed to stay abreast of this developing field

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  • Author : Patrick Arbuthnot
  • Publisher : Academic Press
  • Pages : 392 pages
  • ISBN : 0124114520
  • Rating : 4/5 from 21 reviews
CLICK HERE TO GET THIS BOOKGene Therapy for Viral Infections

Gene Therapy for Viral Infections

Gene Therapy for Viral Infections
  • Author : Patrick Arbuthnot
  • Publisher : Academic Press
  • Release : 01 June 2015
GET THIS BOOKGene Therapy for Viral Infections

Gene Therapy for Viral Infections provides a comprehensive review of the broader field of nucleic acid and its use in treating viral infections. The text bridges the gap between basic science and important clinical applications of the technology, providing a systematic, integrated review of the advances in nucleic acid-based antiviral drugs and the potential advantages of new technologies over current treatment options. Coverage begins with the fundamentals, exploring varying topics, including harnessing RNAi to silence viral gene expression, antiviral gene

Gene Therapy for HIV and Chronic Infections

Gene Therapy for HIV and Chronic Infections
  • Author : Ben Berkhout,Hildegund C.J. Ertl,Marc S. Weinberg
  • Publisher : Springer
  • Release : 10 March 2015
GET THIS BOOKGene Therapy for HIV and Chronic Infections

This book centers on gene therapy and gene transfer approaches to prevent or treat chronic virus infections. The main focus is on the Big Three: human immunodeficiency virus (HIV-1), hepatitis B virus (HBV) and hepatitis C virus (HCV). Ample anti-HIV drugs are currently available in the clinic and the development of an effective combination therapy has dramatically improved the lifespan and quality of life of infected individuals. A similar trend can already be recognized for HBV and HCV: the development

Cancer Gene Therapy

Cancer Gene Therapy
  • Author : David T. Curiel,Joanne T. Douglas
  • Publisher : Springer Science & Business Media
  • Release : 03 November 2007
GET THIS BOOKCancer Gene Therapy

A complete introduction and guide to the latest developments in cancer gene therapy-from bench to bedside. The authors comprehensively review the anticancer genes and gene delivery methods currently available for cancer gene therapy, including the transfer of genetic material into the cancer cells, stimulation of the immune system to recognize and eliminate cancer cells, and the targeting of the nonmalignant stromal cells that support their growth. They also thoroughly examine the advantages and limitations of the different therapies and detail

Gene Therapy for HIV and Chronic Infections

Gene Therapy for HIV and Chronic Infections
  • Author : Ben Berkhout,Hildegund C.J. Ertl,Marc S. Weinberg
  • Publisher : Unknown Publisher
  • Release : 17 October 2021
GET THIS BOOKGene Therapy for HIV and Chronic Infections

This volume examines gene therapy and gene transfer approaches to preventing or treating chronic virus infections, focusing on the Big Three viral pathogens- HIV, hepatitis B virus (HBV), and hepatitis C virus (HCV). It explores molecular antiviral strategies, including RNA interference, aptamer-siRNA chimeras, U1i interference, editing CCR5, alternative genetic vaccination by intramuscular gene transfers of virus vectors, and HIV latency in the context of non-coding RNA. This title is a volume of the American Society of Gene and Cell

Persistent Viral Infections

Persistent Viral Infections
  • Author : R. Ahmed,Irvin Chen
  • Publisher : Wiley-Blackwell
  • Release : 17 October 1999
GET THIS BOOKPersistent Viral Infections

Persistent Viral Infections Edited by Rafi Ahmed Emory Vaccine Center, Atlanta, USA and Irvin S. Y. Chen UCLA School of Medicine, Los Angeles, USA During the past decade much of our attention has focused on diseases associated with viral persistence. Major breakthroughs in immunology, and the advent of molecular approaches to study pathogenesis have increased our understanding of the complex virus-host interactions that occur during viral persistence. Persistent Viral Infections focuses on: * The pathogenesis and immunology of chronic infections * Animal

Gene Therapy of Cancer

Gene Therapy of Cancer
  • Author : Wolfgang Walther,Ulrike Stein
  • Publisher : Springer Science & Business Media
  • Release : 17 October 2021
GET THIS BOOKGene Therapy of Cancer

In Gene Therapy of Cancer: Methods and Protocols, Wolfgang Walther and Ulrike Stein survey the rapidly evolving field cancer gene therapy and provide a broad array of leading-edge protocols for the delivery of therapeutic genes into tumors. Described in step-by-step fashion and enriched with each author's own practical tips, these readily reproducible methods are currently being widely applied in cancer gene therapy investigations, including immunotherapy and tumor vaccination, suicide gene therapy, antioncogene therapy, and antisense and ribozyme gene therapy. Representative

Essential Human Virology

Essential Human Virology
  • Author : Jennifer Louten
  • Publisher : Academic Press
  • Release : 29 March 2016
GET THIS BOOKEssential Human Virology

Essential Human Virology is written for the undergraduate level with case studies integrated into each chapter. The structure and classification of viruses will be covered, as well as virus transmission and virus replication strategies based upon type of viral nucleic acid. Several chapters will focus on notable and recognizable viruses and the diseases caused by them, including influenza, HIV, hepatitis viruses, poliovirus, herpesviruses, and emerging and dangerous viruses. Additionally, how viruses cause disease, or pathogenesis, will be highlighted during the

Gene Therapy

Gene Therapy
  • Author : Doaa Hashad
  • Publisher : BoD – Books on Demand
  • Release : 26 November 2015
GET THIS BOOKGene Therapy

Gene therapy is becoming a promising technology for the management of many human diseases. Hereditary and acquired disorders can both be tackled using the technique of gene therapy. This book provides detailed, up-to-date topics addressing basic principles of gene therapy and discussing some of the challenges encountered by scientists in developing this relatively novel technology. The development of new and efficient gene transfer vectors is of utmost importance in the progress of the field of gene therapy. Both viral and

Pharmaceutical Biotechnology

Pharmaceutical Biotechnology
  • Author : Carlos A. Guzmán,Giora Z. Feuerstein
  • Publisher : Springer Science & Business Media
  • Release : 01 January 2010
GET THIS BOOKPharmaceutical Biotechnology

Pharmaceutical Biotechnology is a unique compilation of reviews addressing frontiers in biologicals as a rich source for innovative medicines. This book fulfills the needs of a broad community of scientists interested in biologicals from diverse perspectives—basic research, biotechnology, protein engineering, protein delivery, medicines, pharmaceuticals and vaccinology. The diverse topics range from advanced biotechnologies aimed to introduce novel, potent engineered vaccines of unprecedented efficacy and safety for a wide scope of human diseases to natural products, small peptides and polypeptides

Modern Tools for Genetic Engineering

Modern Tools for Genetic Engineering
  • Author : Michael Kormann
  • Publisher : BoD – Books on Demand
  • Release : 18 May 2016
GET THIS BOOKModern Tools for Genetic Engineering

Site-specific endonucleases create double-strand breaks within the genome and can be targeted to literally any genetic mutation. Together with a repair template, a correction of the defective locus becomes possible. This book offers insight into the modern tools of genome editing, their hurdles and their huge potential. A new era of in vivo genetic engineering has begun.

Novel Gene Therapy Approaches

Novel Gene Therapy Approaches
  • Author : Ming Wei,David Good
  • Publisher : BoD – Books on Demand
  • Release : 13 February 2013
GET THIS BOOKNovel Gene Therapy Approaches

Gene therapy has the potential to be a tailor-made therapeutic with increased specificity and decreased side effects that can offer a "cure" for many disorders. The aim of this book is to provide up-to-date reviews of the rapidly growing field of gene therapy. Chapters cover a large range of topics including methods of gene delivery, and identification of targets with several papers on cancer gene therapy. If more people become aware of the true nature and potential of gene therapy,

Gene Therapy for Acute and Acquired Diseases

Gene Therapy for Acute and Acquired Diseases
  • Author : Phillip Factor
  • Publisher : Springer Science & Business Media
  • Release : 31 January 2001
GET THIS BOOKGene Therapy for Acute and Acquired Diseases

In recent years much enthusiasm and energy has been directed toward the development of human gene therapies, especially for inherited conditions and cancers. However, current gene transfer technology is limited in its transduction efficiency and ability to permanently and safely correct genomic defects. Thus the promise of gene therapy for these conditions is as yet unrealized. The progression of gene transfer technology will eventually surmount these limitations. Gene Therapy for Acute and Acquired Diseases includes selected examples of ongoing studies

The Influenza Viruses

The Influenza Viruses
  • Author : Robert M. Krug
  • Publisher : Springer Science & Business Media
  • Release : 06 December 2012
GET THIS BOOKThe Influenza Viruses

Influenza virus is an important human pathogen, frequently causing widespread disease and a significant loss of life. Much has been learned about the structure of the virus, its genetic variation, its mode of gene expression and replication, and its interaction with the host immu nologic system. This knowledge has the potential of leading to ap proaches for the control of influenza virus. In addition, research on influ enza virus has led to important advances in eukaryotic molecular and cellular biology

Viral Gene Therapy

Viral Gene Therapy
  • Author : Ke Xu
  • Publisher : BoD – Books on Demand
  • Release : 20 July 2011
GET THIS BOOKViral Gene Therapy

The development of technologies that allow targeting of specific cells has progressed substantially in recent years for several types of vectors, particularly viral vectors, which have been used in 70% of gene therapy clinical trials. Particular viruses have been selected as gene delivery vehicles because of their capacities to carry foreign genes and their ability to efficiently deliver these genes associated with efficient gene expression. This book is designed to present the most recent advances in viral gene therapy

Neurotropic Viral Infections

Neurotropic Viral Infections
  • Author : Carol Shoshkes Reiss
  • Publisher : Springer
  • Release : 08 September 2016
GET THIS BOOKNeurotropic Viral Infections

This second edition is a comprehensive study of the viruses that affect the brain and the central nervous system. Along with a focus on the viruses themselves, it addresses the diseases they cause, current treatments and preventive measures. Also discussed are the unique aspects of how viruses cause disease and why certain hosts are more susceptible (e.g., polymorphisms, age, co-morbidities). Because there are 29 cutting edge chapters, written by experts in the fields, Neurotropic Viral Infections has been divided into