Gene Therapy in Neurological Disorders

Gene therapy has tremendous potential for the treatment of neurological disorders. There has been substantial progress in the development of gene therapy strategies for neurological disorders over the last two decades. Gene Therapy in Neurological Disorders thoroughly reviews currently available gene therapy tools and presents examples of their application in a variety of neurological diseases. The book begins with general reviews of gene therapy strategies with a focus on neurological disorders. The remainder of the chapters present approaches to specific neurological disorders. Each chapter gives an in-depth introduction to the relevant field before diving into the specific tool or application. The book aims to help investigators, students and research staff better understand the principles of gene therapy and its application in the nervous system. Provides background information and experimental details of gene therapy tools applied for neuroscience research and neurological disorders Covers a broad range of gene delivery and regulation tools, therapeutic agents, and target cells, including emerging new technologies such as CRISPR/Cas9 genome editing Discusses applications of gene therapy tools to neurological disorders including neurodegeneration, muscular dystrophy, trauma and chronic pain, and neoplastic diseases

Produk Detail:

  • Author : Mingjie Li
  • Publisher : Academic Press
  • Pages : 450 pages
  • ISBN : 012809821X
  • Rating : 4/5 from 21 reviews
CLICK HERE TO GET THIS BOOKGene Therapy in Neurological Disorders

Gene Therapy in Neurological Disorders

Gene Therapy in Neurological Disorders
  • Author : Mingjie Li,B. Joy Snider
  • Publisher : Academic Press
  • Release : 25 May 2018
GET THIS BOOKGene Therapy in Neurological Disorders

Gene therapy has tremendous potential for the treatment of neurological disorders. There has been substantial progress in the development of gene therapy strategies for neurological disorders over the last two decades. Gene Therapy in Neurological Disorders thoroughly reviews currently available gene therapy tools and presents examples of their application in a variety of neurological diseases. The book begins with general reviews of gene therapy strategies with a focus on neurological disorders. The remainder of the chapters present approaches to specific

Gene Therapy for Neurological Disorders

Gene Therapy for Neurological Disorders
  • Author : Frederic P Manfredsson
  • Publisher : Humana Press
  • Release : 26 November 2015
GET THIS BOOKGene Therapy for Neurological Disorders

This volume provides a clear and detailed roadmap of how to design and execute a gene therapy experiment in order to obtain consistent results. Chapters in this book disseminate bits of unknown information that are important to consider during the course of experimentation and will answer questions such as: What delivery vehicle do you use?; How will you ensure that your vector retains stability?; What expression system best fits your needs?; What route will you choose to deliver your gene

Gene Therapy of the Central Nervous System: From Bench to Bedside

Gene Therapy of the Central Nervous System: From Bench to Bedside
  • Author : Michael G. Kaplitt,Matthew During
  • Publisher : Gulf Professional Publishing
  • Release : 08 March 2021
GET THIS BOOKGene Therapy of the Central Nervous System: From Bench to Bedside

Few areas of biomedical research provide greater opportunities for radically new therapies for devastating diseases that have evaded treatment so far than gene therapy. This is particularly true for the brain and nervous system, where gene transfer has become a key technology for basic research and has recently been translated to human therapy in several landmark clinical trials. Gene Therapy of the Central Nervous System: From Bench to Bedside represents the first definitive volume on this subject. Edited by two

Advancing Gene-Targeted Therapies for Central Nervous System Disorders

Advancing Gene-Targeted Therapies for Central Nervous System Disorders
  • Author : National Academies of Sciences, Engineering, and Medicine,Health and Medicine Division,Board on Health Sciences Policy,Forum on Neuroscience and Nervous System Disorders
  • Publisher : National Academies Press
  • Release : 31 October 2019
GET THIS BOOKAdvancing Gene-Targeted Therapies for Central Nervous System Disorders

On April 23 and 24, 2019 the Forum on Neuroscience and Nervous System Disorders convened a workshop titled "Advancing Gene-Targeted Therapies for Central Nervous System Disorders" in Washington, DC. This public workshop brought together experts and key stakeholders from academia, government, industry, philanthropic foundations, and disease/patient-focused nonprofit organizations to explore approaches for advancing the development of gene-targeted therapies for central nervous system (CNS) disorders, and implications of developing these therapies. Participants explored lessons learned from both successful and unsuccessful clinical development programs;

Gene Therapy for Neurological Disorders and Brain Tumors

Gene Therapy for Neurological Disorders and Brain Tumors
  • Author : E. Antonio Chiocca,Xandra O. Breakefield
  • Publisher : Springer Science & Business Media
  • Release : 23 October 1997
GET THIS BOOKGene Therapy for Neurological Disorders and Brain Tumors

Leading gene therapy researchers and clinicians illuminate the field-from basic vector technology to current and future clinical applications in neurology. The authoritative contributors provide cutting-edge reviews of the vectors available for gene transfer to the central nervous system, the strategies against CNS tumors, the potential strategies against neurologic disorder, and the limitations of today's gene therapy approaches. Also discussed are significant applications of gene therapy to brain tumors, Parkinson's disease, ischemia, and Huntington's chorea. Readers will learn the current delivery

Physical Disabilities

Physical Disabilities
  • Author : Uner Tan
  • Publisher : BoD – Books on Demand
  • Release : 14 June 2017
GET THIS BOOKPhysical Disabilities

This book, Physical Disabilities - Therapeutic Implications, presents reports on a wide range of areas in the field of neurobiological disabilities, including movement disorders (Uner Tan syndrome, genetic and environmental influences, chronic brain damage, stroke, and pediatric disabilities) related to physical and stem cell therapy. Studies are presented from researchers around the world, looking at aspects as wide-ranging as the genetics, wheelchair, and robotics behind the conditions to new and innovative therapeutic approaches.

Selected Topics in Neonatal Care

Selected Topics in Neonatal Care
  • Author : René Mauricio Barría
  • Publisher : BoD – Books on Demand
  • Release : 27 June 2018
GET THIS BOOKSelected Topics in Neonatal Care

Neonatology is one of the areas of greatest development and evolution within pediatrics. The technoscientific advances in this area have led to an increase in the survival of premature infants who sometimes require sophisticated care. However, there is essential care that must be included in all centers that care for high-risk babies. This book includes important topics related to neonatal care grouped into four sections. In 14 chapters that address relevant issues about neonatal care, the book seeks to contribute to

Gene Therapy

Gene Therapy
  • Author : Doaa Hashad
  • Publisher : BoD – Books on Demand
  • Release : 26 November 2015
GET THIS BOOKGene Therapy

Gene therapy is becoming a promising technology for the management of many human diseases. Hereditary and acquired disorders can both be tackled using the technique of gene therapy. This book provides detailed, up-to-date topics addressing basic principles of gene therapy and discussing some of the challenges encountered by scientists in developing this relatively novel technology. The development of new and efficient gene transfer vectors is of utmost importance in the progress of the field of gene therapy. Both viral and

Current Concepts in Movement Disorder Management

Current Concepts in Movement Disorder Management
  • Author : A. Niranjan,L.D. Lunsford,R.M. Richardson
  • Publisher : Karger Medical and Scientific Publishers
  • Release : 12 January 2018
GET THIS BOOKCurrent Concepts in Movement Disorder Management

This book summarizes the current state of movement disorder management and the role of surgical therapies as an alternative to medication. Following a chapter on the history of movement disorder surgery, leaders in their fields describe the pathophysiology, functional neuroanatomy, clinical presentation, and medical management of Parkinson’s disease, dystonia, and essential tremor. This is followed by chapters on the spectrum of movement disorder surgery itself, from the lesioning procedures of radiofrequency ablation, stereotactic radiosurgery, and high-frequency ultrasound to the

Current Therapy in Neurologic Disease

Current Therapy in Neurologic Disease
  • Author : Richard Tidball Johnson,John W. Griffin,Justin C. McArthur
  • Publisher : Mosby
  • Release : 08 March 2021
GET THIS BOOKCurrent Therapy in Neurologic Disease

Neurologists present their own experiences and step-by-step guidelines on the management and treatment of specific disorders affecting the nervous system. Diagnosis, epidemiology, and pathophysiology are discussed only when they affect treatment strategies and decisions. Treatment algorithms and patient resource information complement each chapter.

Gene Therapy

Gene Therapy
  • Author : David Cooper,Prof Nick Lemoine
  • Publisher : Garland Science
  • Release : 11 September 2020
GET THIS BOOKGene Therapy

Gene Therapy describes the delivery systems now available to target a given tissue with specific gene or oligonucleotide sequences, and explores the utility of animal modules as test systems. In the context of selected disease states, it summarises in vitro and in vivo studies and clinical trials performed to date.

The Right Therapy for Neurological Disorders

The Right Therapy for Neurological Disorders
  • Author : E. Beghi,G. Logroscino
  • Publisher : Karger Medical and Scientific Publishers
  • Release : 26 July 2016
GET THIS BOOKThe Right Therapy for Neurological Disorders

Most neurological disorders are chronic and aging-related. With the increase of life expectancy their incidence and prevalence will grow in the decades to come, which in turn will increase the load on medical and social systems worldwide. There is thus a desperate need for successful preventive and therapeutic measures based on randomized clinical trials (RTCs) conducted by independent organizations. This book provides a compendium relating most of the principles of reliable RTCs to specific neurological diseases. Contributed by specialized neurologists,

Stem Cell and Gene Therapy for Cardiovascular Disease

Stem Cell and Gene Therapy for Cardiovascular Disease
  • Author : Emerson C. Perin,Leslie W. Miller,Doris Taylor,James T. Willerson
  • Publisher : Academic Press
  • Release : 21 August 2015
GET THIS BOOKStem Cell and Gene Therapy for Cardiovascular Disease

Stem Cell and Gene Therapy for Cardiovascular Disease is a state-of-the-art reference that combines, in one place, the breadth and depth of information available on the topic. As stem cell and gene therapies are the most cutting-edge therapies currently available for patients with heart failure, each section of the book provides information on medical trials from contributors and specialists from around the world, including not only what has been completed, but also what is planned for future research and trials.

Molecular Neurology

Molecular Neurology
  • Author : Stephen Waxman
  • Publisher : Elsevier
  • Release : 26 July 2010
GET THIS BOOKMolecular Neurology

Why a book on molecular neurology? Molecular neuroscience is advancing at a spectacular rate. As it does so, it is revealing important clues to the pathogenesis and pathophysiology of neurological diseases, and to the therapeutic targets that they present. Medicines work by targeting molecules. The more specific the targeting, the more specific the actions, and the fewer the side effects. Molecular Neurology highlights, for graduate and MD-PhD students, research fellows and research-oriented clinical fellows, and researchers in the neurosciences and