Gene Therapy in Neurological Disorders

Gene therapy has tremendous potential for the treatment of neurological disorders. There has been substantial progress in the development of gene therapy strategies for neurological disorders over the last two decades. Gene Therapy in Neurological Disorders thoroughly reviews currently available gene therapy tools and presents examples of their application in a variety of neurological diseases. The book begins with general reviews of gene therapy strategies with a focus on neurological disorders. The remainder of the chapters present approaches to specific neurological disorders. Each chapter gives an in-depth introduction to the relevant field before diving into the specific tool or application. The book aims to help investigators, students and research staff better understand the principles of gene therapy and its application in the nervous system. Provides background information and experimental details of gene therapy tools applied for neuroscience research and neurological disorders Covers a broad range of gene delivery and regulation tools, therapeutic agents, and target cells, including emerging new technologies such as CRISPR/Cas9 genome editing Discusses applications of gene therapy tools to neurological disorders including neurodegeneration, muscular dystrophy, trauma and chronic pain, and neoplastic diseases

Produk Detail:

  • Author : Mingjie Li
  • Publisher : Academic Press
  • Pages : 450 pages
  • ISBN : 012809821X
  • Rating : 4/5 from 21 reviews
CLICK HERE TO GET THIS BOOKGene Therapy in Neurological Disorders

Gene Therapy in Neurological Disorders

Gene Therapy in Neurological Disorders
  • Author : Mingjie Li,B. Joy Snider
  • Publisher : Academic Press
  • Release : 25 May 2018
GET THIS BOOKGene Therapy in Neurological Disorders

Gene therapy has tremendous potential for the treatment of neurological disorders. There has been substantial progress in the development of gene therapy strategies for neurological disorders over the last two decades. Gene Therapy in Neurological Disorders thoroughly reviews currently available gene therapy tools and presents examples of their application in a variety of neurological diseases. The book begins with general reviews of gene therapy strategies with a focus on neurological disorders. The remainder of the chapters present approaches to specific

Gene Therapy for Neurological Disorders

Gene Therapy for Neurological Disorders
  • Author : Pedro R. Lowenstein,Maria G. Castro
  • Publisher : CRC Press
  • Release : 01 May 2006
GET THIS BOOKGene Therapy for Neurological Disorders

Coedited by internationally recognized leaders in gene therapy research, this guide supplies the most recent advances, studies, and expert opinion on gene therapy for neurological disorders. Spanning conditions such as Parkinsons's and Alzheimer's disease, multiple sclerosis, brain tumors, stroke, epilepsy, and brain and spinal cord trauma, this reference presents the basic science and applications of recombinant gene products, immune and stem cell-mediated therapeutic strategies, and brain tumor gene therapy.

Gene Therapy for Neurological Disorders and Brain Tumors

Gene Therapy for Neurological Disorders and Brain Tumors
  • Author : E. Antonio Chiocca,Xandra O. Breakefield
  • Publisher : Springer Science & Business Media
  • Release : 23 October 1997
GET THIS BOOKGene Therapy for Neurological Disorders and Brain Tumors

Leading gene therapy researchers and clinicians illuminate the field-from basic vector technology to current and future clinical applications in neurology. The authoritative contributors provide cutting-edge reviews of the vectors available for gene transfer to the central nervous system, the strategies against CNS tumors, the potential strategies against neurologic disorder, and the limitations of today's gene therapy approaches. Also discussed are significant applications of gene therapy to brain tumors, Parkinson's disease, ischemia, and Huntington's chorea. Readers will learn the current delivery

Gene Therapy

Gene Therapy
  • Author : Doaa Hashad
  • Publisher : BoD – Books on Demand
  • Release : 26 November 2015
GET THIS BOOKGene Therapy

Gene therapy is becoming a promising technology for the management of many human diseases. Hereditary and acquired disorders can both be tackled using the technique of gene therapy. This book provides detailed, up-to-date topics addressing basic principles of gene therapy and discussing some of the challenges encountered by scientists in developing this relatively novel technology. The development of new and efficient gene transfer vectors is of utmost importance in the progress of the field of gene therapy. Both viral and

Advancing Gene-Targeted Therapies for Central Nervous System Disorders

Advancing Gene-Targeted Therapies for Central Nervous System Disorders
  • Author : National Academies of Sciences, Engineering, and Medicine,Health and Medicine Division,Board on Health Sciences Policy,Forum on Neuroscience and Nervous System Disorders
  • Publisher : National Academies Press
  • Release : 31 October 2019
GET THIS BOOKAdvancing Gene-Targeted Therapies for Central Nervous System Disorders

On April 23 and 24, 2019 the Forum on Neuroscience and Nervous System Disorders convened a workshop titled "Advancing Gene-Targeted Therapies for Central Nervous System Disorders" in Washington, DC. This public workshop brought together experts and key stakeholders from academia, government, industry, philanthropic foundations, and disease/patient-focused nonprofit organizations to explore approaches for advancing the development of gene-targeted therapies for central nervous system (CNS) disorders, and implications of developing these therapies. Participants explored lessons learned from both successful and unsuccessful clinical development programs;

Gene Therapy of the Central Nervous System: From Bench to Bedside

Gene Therapy of the Central Nervous System: From Bench to Bedside
  • Author : Michael G. Kaplitt,Matthew During
  • Publisher : Gulf Professional Publishing
  • Release : 28 October 2021
GET THIS BOOKGene Therapy of the Central Nervous System: From Bench to Bedside

Few areas of biomedical research provide greater opportunities for radically new therapies for devastating diseases that have evaded treatment so far than gene therapy. This is particularly true for the brain and nervous system, where gene transfer has become a key technology for basic research and has recently been translated to human therapy in several landmark clinical trials. Gene Therapy of the Central Nervous System: From Bench to Bedside represents the first definitive volume on this subject. Edited by two

Gene Therapy Methods

Gene Therapy Methods
  • Author : M. Ian Phillips
  • Publisher : Academic Press
  • Release : 28 October 2021
GET THIS BOOKGene Therapy Methods

This volume in the prestigious Methods in Enzymology series discusses methods currently used in preclinical and clinical gene therapy. Subjects covered in this book, such as the use of adeno-associated virus delivery for treatment of Parkinson's disease, are topical and are presented in the methods-oriented style popularized by this series. This volume in the prestigious Methods in Enzymology series discusses methods currently used in preclinical and clinical gene therapy. Subjects covered in this book, such as the use of adeno-associated

Handbook of Innovations in Central Nervous System Regenerative Medicine

Handbook of Innovations in Central Nervous System Regenerative Medicine
  • Author : António Salgado
  • Publisher : Elsevier
  • Release : 10 June 2020
GET THIS BOOKHandbook of Innovations in Central Nervous System Regenerative Medicine

Handbook of Innovations in CNS Regenerative Medicine provides a comprehensive overview of the CNS regenerative medicine field. The book describes the basic biology and anatomy of the CNS and how injury and disease affect its balance and the limitations of the present therapies used in the clinics. It also introduces recent trends in different fields of CNS regenerative medicine, including cell transplantation, bio and neuro-engineering, molecular/pharmacotherapy therapies and enabling technologies. Finally, the book presents successful cases of translation of

Current Concepts in Movement Disorder Management

Current Concepts in Movement Disorder Management
  • Author : A. Niranjan,L.D. Lunsford,R.M. Richardson
  • Publisher : Karger Medical and Scientific Publishers
  • Release : 12 January 2018
GET THIS BOOKCurrent Concepts in Movement Disorder Management

This book summarizes the current state of movement disorder management and the role of surgical therapies as an alternative to medication. Following a chapter on the history of movement disorder surgery, leaders in their fields describe the pathophysiology, functional neuroanatomy, clinical presentation, and medical management of Parkinson’s disease, dystonia, and essential tremor. This is followed by chapters on the spectrum of movement disorder surgery itself, from the lesioning procedures of radiofrequency ablation, stereotactic radiosurgery, and high-frequency ultrasound to the

Animal Models of Neurological Disorders

Animal Models of Neurological Disorders
  • Author : Puneet Kumar Bansal,Rahul Deshmukh
  • Publisher : Springer
  • Release : 17 January 2018
GET THIS BOOKAnimal Models of Neurological Disorders

This book introduces undergraduate, postgraduate and research students and scientists to animal models of neurological disorders, along with their working principle and brief procedures. Addressing all the disorders related to the central nervous system (CNS) in a single platform, on the basis of various literature surveys it describes different procedures to induce a single disease with the help of toxins/chemicals. It also includes numerous protocols for inducing single neurological diseases, thus fulfilling an urgent need for a book that

Gene Therapy for Neurological Disorders

Gene Therapy for Neurological Disorders
  • Author : Frederic P Manfredsson
  • Publisher : Humana Press
  • Release : 26 November 2015
GET THIS BOOKGene Therapy for Neurological Disorders

This volume provides a clear and detailed roadmap of how to design and execute a gene therapy experiment in order to obtain consistent results. Chapters in this book disseminate bits of unknown information that are important to consider during the course of experimentation and will answer questions such as: What delivery vehicle do you use?; How will you ensure that your vector retains stability?; What expression system best fits your needs?; What route will you choose to deliver your gene

Gene Therapy for Neurological Disorders

Gene Therapy for Neurological Disorders
  • Author : Fredric P. Manfredsson
  • Publisher : Humana Press
  • Release : 23 August 2016
GET THIS BOOKGene Therapy for Neurological Disorders

This volume provides a clear and detailed roadmap of how to design and execute a gene therapy experiment in order to obtain consistent results. Chapters in this book disseminate bits of unknown information that are important to consider during the course of experimentation and will answer questions such as: What delivery vehicle do you use?; How will you ensure that your vector retains stability?; What expression system best fits your needs?; What route will you choose to deliver your gene

Growth Factors as Drugs for Neurological and Sensory Disorders

Growth Factors as Drugs for Neurological and Sensory Disorders
  • Author : Gregory R. Bock,Jamie A. Goode
  • Publisher : John Wiley & Sons
  • Release : 30 April 2008
GET THIS BOOKGrowth Factors as Drugs for Neurological and Sensory Disorders

Degeneration of sensory receptors or of the nerves innervating them leads to a sensory deficit. Various strategies have been tried for promoting regrowth of sensory receptors, particularly in the eye and ear. The latest data from experimental studies in animals are presented in the book including applications of BDNF and CNTF in the eye and epidermal growth factor in the ear.

Pediatric Neurology Part III

Pediatric Neurology Part III
  • Author : Patrick Aubourg
  • Publisher : Elsevier Inc. Chapters
  • Release : 24 April 2013
GET THIS BOOKPediatric Neurology Part III

Though heavily hyped in the early 1990s as the answer to many genetic diseases, gene therapy has largely failed to live up to its promises up to now. The scientific challenges of conveying replacement genes into the brain have prevented it from having an impact on more than a handful of conditions. In addition, gene therapy has been beset by safety problems. During the last 5 years, new vectors and techniques have started to resolve not only safety issues that once

Neurotherapeutics in the Era of Translational Medicine

Neurotherapeutics in the Era of Translational Medicine
  • Author : Richard A. Smith,Brian K. Kaspar,Clive N. Svendsen
  • Publisher : Academic Press
  • Release : 28 November 2020
GET THIS BOOKNeurotherapeutics in the Era of Translational Medicine

For the first time in history, there is now hope for treating neurological disorders that had previously been considered untreatable. The remarkable confluence of events that has heralded this is the focus of Neurotherapeutics in the Era of Translational Medicine. This anthology, written by many of the prominent scientists and researchers in the field of biotechnology, recounts the breathtaking advances that are revolutionizing treatment for disorders such as amyotrophic lateral sclerosis‎, spinal muscular atrophy, multiple sclerosis, Parkinson’s disease, myasthenia