Genes Environment and Alzheimer s Disease

Genes, Environment and Alzheimer's Disease discusses the role that activities such as exercise can play in cardiovascular health, while also highlighting the fact that the last 10 years have brought great discoveries in the strong environmental component of brain disorders, neurodegeneration, and cognitive decline. It is now clear that brain insult is an environmental risk factor for AD, while on the other hand, lifestyle components such as exercise and level of education may play a protective role, delaying the onset and/or severity of the disease. Evidence from experiments in rodent models of Alzheimer's disease contributes major insight into the molecular mechanisms by which the environment plays its role in AD. Additionally, there are diseases related to lifestyle that may lead to AD. This volume reviews new discoveries related to all these factors, serving as a translational tool for clinicians and researchers interested in genetic and environmental risk factors for the disease. Provides the first volume to link genetic and environmental risk factors for Alzheimer's disease and dementia Aids researchers and clinicians in understanding the basic mechanisms of Alzheimer's disease and cognitive decline Brings the basic science and clinical perspectives together in a single volume, facilitating translational possibilities Includes a range of molecular to behavioral components assembled into a single volume that creates an excellent resource for basic and clinical neuroscientists

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  • Author : Orly Lazarov
  • Publisher : Academic Press
  • Pages : 350 pages
  • ISBN : 9780128028513
  • Rating : 4/5 from 21 reviews
CLICK HERE TO GET THIS BOOKGenes Environment and Alzheimer s Disease

Genes, Environment and Alzheimer's Disease

Genes, Environment and Alzheimer's Disease
  • Author : Orly Lazarov
  • Publisher : Academic Press
  • Release : 01 March 2016
GET THIS BOOKGenes, Environment and Alzheimer's Disease

Genes, Environment and Alzheimer's Disease discusses the role that activities such as exercise can play in cardiovascular health, while also highlighting the fact that the last 10 years have brought great discoveries in the strong environmental component of brain disorders, neurodegeneration, and cognitive decline. It is now clear that brain insult is an environmental risk factor for AD, while on the other hand, lifestyle components such as exercise and level of education may play a protective role, delaying the onset and/

Update on Dementia

Update on Dementia
  • Author : Davide Moretti
  • Publisher : BoD – Books on Demand
  • Release : 28 September 2016
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The dementia challenge is the largest health effort of the times we live in. The whole society has to move to a realization of the significance of prioritization to make an attempt in the direction of mental health promotion and dementia risk reduction. New priorities for research are needed to go far beyond the usual goal of constructing a disease course-modifying medication. Moreover, a full empowerment and engagement of men and women living with dementia and their caregivers, overcoming stigma

Environmental Causes and Prevention Measures for Alzheimer’s Disease

Environmental Causes and Prevention Measures for Alzheimer’s Disease
  • Author : George J. Brewer
  • Publisher : Academic Press
  • Release : 26 September 2017
GET THIS BOOKEnvironmental Causes and Prevention Measures for Alzheimer’s Disease

Environmental Causes and Prevention Measures for Alzheimer’s Disease examines the increased incidence of the disease in developed countries and aims to educate neuroscientists, medical practitioners and other educated individuals on new insights into environmental causation, primarily metals. This book looks into the web of evidence around the hypothesis of copper toxicity and the additional role that a high fat diet plays in disease progression and cognition loss. The data and its implications are discussed, along with potential prevention measures.

Environmental Factors in Neurodevelopmental and Neurodegenerative Disorders

Environmental Factors in Neurodevelopmental and Neurodegenerative Disorders
  • Author : Michael Aschner,Lucio G. Costa
  • Publisher : Academic Press
  • Release : 18 June 2015
GET THIS BOOKEnvironmental Factors in Neurodevelopmental and Neurodegenerative Disorders

Environmental Factors in Neurodevelopmental and Neurodegenerative Disorders presents a state-of-the-art review of the effects of environmental contaminants on the development and degeneration of the human nervous system, brought together by world-leading experts in the field. Part One describes the adverse effects that the environment can have on neurological development, and how these effects may exhibit. Specific contaminants and their possible consequences of exposure are addressed (lead, methylmercury, alcohol), as well as specific disorders and the environmental factors associated with them,

Genetic Variants in Alzheimer's Disease

Genetic Variants in Alzheimer's Disease
  • Author : Kevin Morgan,Minerva M. Carrasquillo
  • Publisher : Springer Science & Business Media
  • Release : 22 June 2013
GET THIS BOOKGenetic Variants in Alzheimer's Disease

Alzheimer’s Disease is the most common form of dementia. The disease is characterised by the loss of synapses and neurons in the cerebral cortex and certain subcortical regions. In the last three years, the genetics of Alzheimer’s Disease has made significant advances; in fact, one could argue more than in the previous two decades. This has resulted in the identification of nine new genes and perhaps more importantly the realization that new pathways could be involved in the

Alzheimer's Disease

Alzheimer's Disease
  • Author : Inga Zerr
  • Publisher : BoD – Books on Demand
  • Release : 01 July 2015
GET THIS BOOKAlzheimer's Disease

There is a wide scope of clinical phenomenology in Alzheimers disease, regarding the age of onset, presenting features, rate of progression and appearance of other clinical manifestation. Although clinical appearance and neuropathological hallmarks have been defining AD since its first description, major factors which trigger pathology are still unknown. The role of comorbidity is discussed controversially. Important environmental risk factors in AD development are continuous stress, low education and cardiovascular risk factors such as alcohol intake, smoking, hypertension. The role

Alzheimer's Disease

Alzheimer's Disease
  • Author : Sangram S. Sisodia,Rudolph E. Tanzi
  • Publisher : Springer Science & Business Media
  • Release : 16 February 2007
GET THIS BOOKAlzheimer's Disease

This book examines every major aspect of Alzheimer disease at a time when there has been no scholarly research volume on the subject published in the last 3-5 years. This edition includes expanded coverage of the cellular-level exploration of related dementing disorders, with in-depth presentation of prion diseases, Pick's disease, fronto-temporal disorders, transgenic models, and biochemistry of presenilins.

Genes, Behavior, and the Social Environment

Genes, Behavior, and the Social Environment
  • Author : Institute of Medicine,Board on Health Sciences Policy,Committee on Assessing Interactions Among Social, Behavioral, and Genetic Factors in Health
  • Publisher : National Academies Press
  • Release : 07 December 2006
GET THIS BOOKGenes, Behavior, and the Social Environment

Over the past century, we have made great strides in reducing rates of disease and enhancing people's general health. Public health measures such as sanitation, improved hygiene, and vaccines; reduced hazards in the workplace; new drugs and clinical procedures; and, more recently, a growing understanding of the human genome have each played a role in extending the duration and raising the quality of human life. But research conducted over the past few decades shows us that this progress, much of

Genomics, Circuits, and Pathways in Clinical Neuropsychiatry

Genomics, Circuits, and Pathways in Clinical Neuropsychiatry
  • Author : Thomas Lehner,Bruce L. Miller,Matthew W. State
  • Publisher : Academic Press
  • Release : 07 June 2016
GET THIS BOOKGenomics, Circuits, and Pathways in Clinical Neuropsychiatry

This foundational work comprehensively examines the current state of the genetics, genomics and brain circuitry of psychiatric and neurological disorders. It consolidates discoveries of specific genes and genomic regions associated with these conditions, the genetic and anatomic architecture of these syndromes, and addresses how recent advances in genomics are leading to a reappraisal of the biology underlying clinical neuroscience. In doing so, it critically examines the promise and limitations of these discoveries toward treatment, and to the interdisciplinary nature of

Rosenberg's Molecular and Genetic Basis of Neurological and Psychiatric Disease

Rosenberg's Molecular and Genetic Basis of Neurological and Psychiatric Disease
  • Author : Roger N. Rosenberg,Juan M. Pascual
  • Publisher : Elsevier
  • Release : 28 October 2014
GET THIS BOOKRosenberg's Molecular and Genetic Basis of Neurological and Psychiatric Disease

Rosenberg’s Molecular and Genetic Basis of Neurologic and Psychiatric Disease, Fifth Edition provides a comprehensive introduction and reference to the foundations and key practical aspects relevant to the majority of neurologic and psychiatric disease. A favorite of over three generations of students, clinicians and scholars, this new edition retains and expands the informative, concise and critical tone of the first edition. This is an essential reference for general medical practitioners, neurologists, psychiatrists, geneticists, and related professionals, and for the

Neurogenetics of Psychiatric Disorders

Neurogenetics of Psychiatric Disorders
  • Author : Akira Sawa,Melvin G. McInnis
  • Publisher : CRC Press
  • Release : 11 May 2007
GET THIS BOOKNeurogenetics of Psychiatric Disorders

Translating bench-based research into effective clinical practice, this source provides a clear understanding of the neurobiology and neurogenetics of psychiatric disorders, the genes responsible for specific psychiatric disorders, and the implications of genetic roots and underlying biology on the development of new diagnostic approaches and treatment therapies for a variety of psychiatric conditions.