Genes Environment and Alzheimer s Disease

Genes, Environment and Alzheimer's Disease discusses the role that activities such as exercise can play in cardiovascular health, while also highlighting the fact that the last 10 years have brought great discoveries in the strong environmental component of brain disorders, neurodegeneration, and cognitive decline. It is now clear that brain insult is an environmental risk factor for AD, while on the other hand, lifestyle components such as exercise and level of education may play a protective role, delaying the onset and/or severity of the disease. Evidence from experiments in rodent models of Alzheimer’s disease contributes major insight into the molecular mechanisms by which the environment plays its role in AD. Additionally, there are diseases related to lifestyle that may lead to AD. This volume reviews new discoveries related to all these factors, serving as a translational tool for clinicians and researchers interested in genetic and environmental risk factors for the disease. Provides the first volume to link genetic and environmental risk factors for Alzheimer’s disease and dementia Aids researchers and clinicians in understanding the basic mechanisms of Alzheimer’s disease and cognitive decline Brings the basic science and clinical perspectives together in a single volume, facilitating translational possibilities Includes a range of molecular to behavioral components assembled into a single volume that creates an excellent resource for basic and clinical neuroscientists

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  • Author : Orly Lazarov
  • Publisher : Academic Press
  • Pages : 448 pages
  • ISBN : 0128028858
  • Rating : 4/5 from 21 reviews
CLICK HERE TO GET THIS BOOKGenes Environment and Alzheimer s Disease

Genes, Environment and Alzheimer's Disease

Genes, Environment and Alzheimer's Disease
  • Author : Orly Lazarov,Giuseppina Tesco
  • Publisher : Academic Press
  • Release : 25 February 2016
GET THIS BOOKGenes, Environment and Alzheimer's Disease

Genes, Environment and Alzheimer's Disease discusses the role that activities such as exercise can play in cardiovascular health, while also highlighting the fact that the last 10 years have brought great discoveries in the strong environmental component of brain disorders, neurodegeneration, and cognitive decline. It is now clear that brain insult is an environmental risk factor for AD, while on the other hand, lifestyle components such as exercise and level of education may play a protective role, delaying the onset and/

Update on Dementia

Update on Dementia
  • Author : Davide Moretti
  • Publisher : BoD – Books on Demand
  • Release : 28 September 2016
GET THIS BOOKUpdate on Dementia

The dementia challenge is the largest health effort of the times we live in. The whole society has to move to a realization of the significance of prioritization to make an attempt in the direction of mental health promotion and dementia risk reduction. New priorities for research are needed to go far beyond the usual goal of constructing a disease course-modifying medication. Moreover, a full empowerment and engagement of men and women living with dementia and their caregivers, overcoming stigma

Environmental Causes and Prevention Measures for Alzheimer’s Disease

Environmental Causes and Prevention Measures for Alzheimer’s Disease
  • Author : George J. Brewer
  • Publisher : Academic Press
  • Release : 26 September 2017
GET THIS BOOKEnvironmental Causes and Prevention Measures for Alzheimer’s Disease

Environmental Causes and Prevention Measures for Alzheimer’s Disease examines the increased incidence of the disease in developed countries and aims to educate neuroscientists, medical practitioners and other educated individuals on new insights into environmental causation, primarily metals. This book looks into the web of evidence around the hypothesis of copper toxicity and the additional role that a high fat diet plays in disease progression and cognition loss. The data and its implications are discussed, along with potential prevention measures.

Genetic Variants in Alzheimer's Disease

Genetic Variants in Alzheimer's Disease
  • Author : Kevin Morgan,Minerva M. Carrasquillo
  • Publisher : Springer Science & Business Media
  • Release : 22 June 2013
GET THIS BOOKGenetic Variants in Alzheimer's Disease

Alzheimer’s Disease is the most common form of dementia. The disease is characterised by the loss of synapses and neurons in the cerebral cortex and certain subcortical regions. In the last three years, the genetics of Alzheimer’s Disease has made significant advances; in fact, one could argue more than in the previous two decades. This has resulted in the identification of nine new genes and perhaps more importantly the realization that new pathways could be involved in the

Behavior Genetics of Cognition Across the Lifespan

Behavior Genetics of Cognition Across the Lifespan
  • Author : Deborah Finkel,Chandra A. Reynolds
  • Publisher : Springer Science & Business Media
  • Release : 09 July 2013
GET THIS BOOKBehavior Genetics of Cognition Across the Lifespan

Along with psychopathology, cognition has been one of the primary phenotypic focal points of the field of behavior genetics since its inception. Francis Galton’s 1874 examination of eminent families in Britain was among the earliest attempts to investigate whether cognitive achievements run in families. This volume presents current methodologies for understanding cognitive abilities that move beyond the outdated nature vs. nurture paradigm. Recent advances in both collection and statistical modeling of twin data, particularly longitudinal twin data, make this an

Apolipoprotein E and Alzheimer’s Disease

Apolipoprotein E and Alzheimer’s Disease
  • Author : A.D. Roses,K.H. Weisgraber,Y. Christen
  • Publisher : Springer Science & Business Media
  • Release : 06 December 2012
GET THIS BOOKApolipoprotein E and Alzheimer’s Disease

There is now considerable genetic evidence that the type 4 allele of the apolipoprotein E gene is a major susceptibility factor associated with late-onset Alzheimer's disease, the common form of the disease defined as starting after sixty years of age. The role of apolipoprotein E in normal brain metabolism and in the pathogenesis of Alzheimer's disease are new and exciting avenues of research. This book, written by the most outstanding scientists in this new filed, is the first presentation of results

Epidemiology of Alzheimer’s Disease: From Gene to Prevention

Epidemiology of Alzheimer’s Disease: From Gene to Prevention
  • Author : Richard Mayeux
  • Publisher : Springer Science & Business Media
  • Release : 06 December 2012
GET THIS BOOKEpidemiology of Alzheimer’s Disease: From Gene to Prevention

This volume contains the proceedings of the 14th Colloque Médecine et Recherche of the Fondation Ipsen pour la Recherche Thérapeutique devoted to Alzheimer's Disease and dedicated to the epidemiological study of this dementia, a very important issue because the incidence and prevalence of Alzheimer's Disease rise exponentially with age. Epidemiological findings not only confirm dementia as a major challenge for the coming years but also contribute defining risk factors, predicting and may be preventing this disease.

Neuroepigenomics in Aging and Disease

Neuroepigenomics in Aging and Disease
  • Author : Raul Delgado-Morales
  • Publisher : Springer
  • Release : 18 May 2017
GET THIS BOOKNeuroepigenomics in Aging and Disease

Epigenetic mechanisms (DNA modifications, histone alterations and non-coding RNAs) are crucial for transcriptional regulation and alterations of the “physiological epigenome” are increasingly associated with human diseases. During the last decade the emerging field of neuroepigenomics have started to impact tremendously in areas such learning and memory, addiction or neurodegeneration. This expert volume covers the role of epigenetic molecular mechanism in regulation of central nervous system’s function, one of the most exciting areas of contemporary molecular neuroscience. The book describes

Environmental Factors in Neurodevelopmental and Neurodegenerative Disorders

Environmental Factors in Neurodevelopmental and Neurodegenerative Disorders
  • Author : Michael Aschner,Lucio G. Costa
  • Publisher : Academic Press
  • Release : 18 June 2015
GET THIS BOOKEnvironmental Factors in Neurodevelopmental and Neurodegenerative Disorders

Environmental Factors in Neurodevelopmental and Neurodegenerative Disorders presents a state-of-the-art review of the effects of environmental contaminants on the development and degeneration of the human nervous system, brought together by world-leading experts in the field. Part One describes the adverse effects that the environment can have on neurological development, and how these effects may exhibit. Specific contaminants and their possible consequences of exposure are addressed (lead, methylmercury, alcohol), as well as specific disorders and the environmental factors associated with them,

Gene Environment Interactions

Gene Environment Interactions
  • Author : Moyra Smith
  • Publisher : Academic Press
  • Release : 24 January 2020
GET THIS BOOKGene Environment Interactions

Gene Environment Interactions: Nature and Nurture in the Twenty-first Century offers a rare, synergistic view of ongoing revelations in gene environment interaction studies, drawing together key themes from epigenetics, microbiomics, disease etiology, and toxicology to illuminate pathways for clinical translation and the paradigm shift towards precision medicine. Across eleven chapters, Dr. Smith discusses interactions with the environment, human adaptations to environmental stimuli, pathogen encounters across the centuries, epigenetic modulation of gene expression, transgenerational inheritance, the microbiome's intrinsic effects on human