Genetic Diseases of the Kidney

Genetic approaches have revolutionized our understanding of the fundamental causes of human disease by permitting the identification of specific genes in which variation causes or contributes to susceptibility to, or protection from, disease. More than 2,000 disease genes have been identified in the last 20 years, providing important new insight into the pathophysiology of diseases in every field of medicine. Genetic Diseases of the Kidney offers expert insight into the role of genetic abnormalities in the pathogenesis of abnormal kidney function and kidney disease. Genetic abnormalities are carefully presented within the appropriate physiologic context so that readers will understand not only which genes are linked to which diseases but also which pathways lead from a genetic “disturbance” to the systemic appearance of disease. * Lays the essential foundation of mammalian genetics principles for medical professionals with little or no background in genetics * Analyzes specific renal diseases – both monogenic disorders confined to the kidney and systemic diseases with renal involvement – and explains their genetic causes *World-renowned editors and authors offer expert frameworks for understanding the links between genes and complex clinical disorders (i.e., lupus, diabetes, HIV, and hypertension)

Produk Detail:

  • Author : Richard P. Lifton
  • Publisher : Academic Press
  • Pages : 848 pages
  • ISBN : 9780080924274
  • Rating : 4/5 from 21 reviews
CLICK HERE TO GET THIS BOOKGenetic Diseases of the Kidney

Genetic Diseases of the Kidney

Genetic Diseases of the Kidney
  • Author : Richard P. Lifton,Stefan Somlo,Gerhard H. Giebisch,Donald W. Seldin
  • Publisher : Academic Press
  • Release : 25 February 2009
GET THIS BOOKGenetic Diseases of the Kidney

Genetic approaches have revolutionized our understanding of the fundamental causes of human disease by permitting the identification of specific genes in which variation causes or contributes to susceptibility to, or protection from, disease. More than 2,000 disease genes have been identified in the last 20 years, providing important new insight into the pathophysiology of diseases in every field of medicine. Genetic Diseases of the Kidney offers expert insight into the role of genetic abnormalities in the pathogenesis of abnormal kidney function and

Genetic Diseases of the Kidney

Genetic Diseases of the Kidney
  • Author : Richard P. Lifton
  • Publisher : Academic Press
  • Release : 01 January 2009
GET THIS BOOKGenetic Diseases of the Kidney

Genetic Diseases of the Kidney identifies and analyzes genetic abnormalities causing renal diseases in human subjects. Although in a sense the genome contains all the instructions required for the formation of a phenotype, the information is encoded in an extremely complicated fashion. In primary genetic diseases, the genetic instruction specifies a phenotype clearly linked with a discreet lesion confined to the kidney. However, the genetic disturbance may be imbedded in a complicated physiologic ensemble, so that the nexus between the

Genetic Diseases of the Kidney

Genetic Diseases of the Kidney
  • Author : Richard P. Lifton,Stefan Somlo,Gerhard H. Giebisch,Martin R. Pollak,Donald W. Seldin
  • Publisher : Academic Press
  • Release : 29 December 2008
GET THIS BOOKGenetic Diseases of the Kidney

The second edition of Genetic Diseases of the Kidney explains how the latest technologies in genetics and genomics have had a tremendous impact on the understanding of kidney disease. In the last 5 years, two new generations of genetic and genomic technology have come into wide use that have had a dramatic impact on the understanding of human renal disease. GWAS have led to the identification of more than 1200 robust associations of common genetic variants with common disease – diseases of the

Molecular and Genetic Basis of Renal Disease

Molecular and Genetic Basis of Renal Disease
  • Author : David B. Mount,Martin R. Pollak
  • Publisher : Elsevier Health Sciences
  • Release : 01 March 2021
GET THIS BOOKMolecular and Genetic Basis of Renal Disease

This companion to Brenner and Rector's The Kidney offers a state-of-the-art summary of the most recent advances in renal genetics. Molecular and Genetic Basis for Renal Disease provides the nephrologist with a comprehensive look at modern investigative tools in nephrology research today, and reviews the molecular pathophysiology of the nephron as well as the most common genetic and acquired renal diseases. A comprehensive clinical review of Medelian renal disease is also be included. Detailed review of the molecular anatomy and

Chronic Renal Disease

Chronic Renal Disease
  • Author : Paul L. Kimmel,Mark E. Rosenberg
  • Publisher : Academic Press
  • Release : 28 August 2019
GET THIS BOOKChronic Renal Disease

Chronic Renal Disease, Second Edition, comprehensively investigates the physiology, pathophysiology, treatment and management of chronic kidney disease (CKD). This translational reference takes an in-depth look at CKD with no coverage of dialysis or transplantation. Chapters are devoted to the scientific investigation of chronic kidney disease, the most common problems faced by nephrologists in the management of chronic kidney disease, specific illnesses in the CKD framework, and how the management of CKD in a polycystic kidney disease patient differs from other

Genetic Disorders of the Indian Subcontinent

Genetic Disorders of the Indian Subcontinent
  • Author : Dhavendra Kumar
  • Publisher : Springer Science & Business Media
  • Release : 20 October 2004
GET THIS BOOKGenetic Disorders of the Indian Subcontinent

The population of the Indian subcontinent consists of a fine amalgamation of people from diverse tribal, cultural, religious and social backgrounds. Mortality and morbidity from a vast number of medical and surgical conditions is significant and well above compared to the developed countries. Although a large component of the human health problem is related to infection, malnutrition and other preventable causes, a significant proportion is linked to hereditary factors reflecting in the form of chromosomal, single gene and complex medical

Kidney Development, Disease, Repair and Regeneration

Kidney Development, Disease, Repair and Regeneration
  • Author : Melissa Helen Little
  • Publisher : Academic Press
  • Release : 06 August 2015
GET THIS BOOKKidney Development, Disease, Repair and Regeneration

Kidney Development, Disease, Repair and Regeneration focuses on the molecular and cellular basis of kidney development, exploring the origins of kidney lineages, the development of kidney tissue subcompartments, as well as the genetic and environmental regulation of kidney development. Special coverage is given to kidney stem cells and possible steps towards kidney repair and regeneration. Emphasis is placed on the fetal origins of postnatal renal disease and our current understanding of the molecular basis of damage and repair. Biomedical researchers

Inherited Disorders of the Kidney

Inherited Disorders of the Kidney
  • Author : Stephen H. Morgan,Jean-Pierre Grünfeld
  • Publisher : Oxford University Press, USA
  • Release : 01 March 1998
GET THIS BOOKInherited Disorders of the Kidney

A high proportion of adults with end-stage renal failure are suffering from an inherited disorder of the kidneys. This is the first book to present a practical approach to the investigation and management of people with inherited renal disorders. Taking an international perspective, it coversthe dramatic clinical and scientific advances that have been made in the past decade.

Comprehensive Pediatric Nephrology E-Book

Comprehensive Pediatric Nephrology E-Book
  • Author : Denis F. Geary,Franz Schaefer
  • Publisher : Elsevier Health Sciences
  • Release : 16 May 2008
GET THIS BOOKComprehensive Pediatric Nephrology E-Book

This new clinical resource brings you a state-of-the-art comprehensive review on every clinical condition encountered in pediatric nephrology in one concise, clinically focused text. International experts provide you with the latest on epidemiology, diagnosis, investigations, management, and prognosis for a full range of pediatric kidney disorders. A full-color, highly visual, meticulously crafted format, makes this material remarkably easy for you to access and apply. Comprehensive Pediatric Nephrology also serves as an ideal resource for board review study for the ABP

Polycystic Kidney Disease

Polycystic Kidney Disease
  • Author : Jinghua Hu,Yong Yu
  • Publisher : CRC Press
  • Release : 13 November 2019
GET THIS BOOKPolycystic Kidney Disease

This volume focuses on the investigatory methods applied to autosomal dominant polycystic kidney disease (ADPKD), one of the most common human genetic diseases. ADPKD is caused by mutations in PKD1 and TRPP2, two integral membrane proteins that function as receptor/ion channels in primary cilia of tubular epithelial cells. Thus, ADPKD belongs to ciliopathies, a group of disorders caused by abnormal cilia formation or function. This proposed book will cover the state-of-the-art methods ranging from molecular biology, biochemistry, electrophysiology, to

Assessing Genetic Risks

Assessing Genetic Risks
  • Author : Institute of Medicine,Committee on Assessing Genetic Risks
  • Publisher : National Academies Press
  • Release : 01 January 1994
GET THIS BOOKAssessing Genetic Risks

Raising hopes for disease treatment and prevention, but also the specter of discrimination and "designer genes," genetic testing is potentially one of the most socially explosive developments of our time. This book presents a current assessment of this rapidly evolving field, offering principles for actions and research and recommendations on key issues in genetic testing and screening. Advantages of early genetic knowledge are balanced with issues associated with such knowledge: availability of treatment, privacy and discrimination, personal decisionmaking, public health

Chronic Kidney Disease

Chronic Kidney Disease
  • Author : Thomas Rath
  • Publisher : BoD – Books on Demand
  • Release : 21 February 2018
GET THIS BOOKChronic Kidney Disease

Known worldwide, chronic kidney disease (CKD) is a disease that affects up to 4% of the population with increasing figures also in the developing countries. Life expectancy of patients affected by CKD is shortened compared to the overall population, and only a minority of patients reach end-stage renal disease (ESRD) with the need for dialysis or renal transplantation; death overtakes dialysis. In the 13 chapters, this book sheds light on the different aspects related to pathophysiology and clinical aspects of CKD, providing

Nephrology Secrets

Nephrology Secrets
  • Author : Edgar V. Lerma,Allen R. Nissenson
  • Publisher : Elsevier Health Sciences
  • Release : 21 June 2011
GET THIS BOOKNephrology Secrets

Nephrology Secrets, 3rd Edition, by Drs. Edgar V. Lerma and Allen R. Nissenson, gives you the nephrology answers you need to succeed on your rotations and boards.. Its unique, highly practical question-and-answer format, list of the "Top 100 Nephrology Secrets," and user-friendly format make it perfect for quick reference. Get the most return for your study time with the proven Secrets® format -- concise, easy to read, and highly effective. Skim the "Top 100 Secrets" and "Key Points" boxes for a fast

Pediatric Kidney Disease

Pediatric Kidney Disease
  • Author : Denis F. Geary,Franz Schaefer
  • Publisher : Springer
  • Release : 16 February 2017
GET THIS BOOKPediatric Kidney Disease

The new edition of this valuable clinical resource offers a state of the art, comprehensive review on every clinical condition encountered in pediatric nephrology. International experts present the latest knowledge on epidemiology, diagnosis, management, and prognosis in one concise, clinically focused text, in which care has been taken to couple just the right amount of "need-to-know" basic science with practical clinical guidance that will enable the reader to make efficient, informed decisions. The topics covered include: disorders of renal development,