Genome Engineering via CRISPR Cas9 System

Genome Engineering via CRISPR-Cas9 Systems presents a compilation of chapters from eminent scientists from across the globe who have established expertise in working with CRISPR-Cas9 systems. Currently, targeted genome engineering is a key technology for basic science, biomedical and industrial applications due to the relative simplicity to which they can be designed, used and applied. However, it is not easy to find relevant information gathered in a single source. The book contains a wide range of applications of CRISPR in research of bacteria, virus, algae, plant and mammalian and also discusses the modeling of drosophila, zebra fish and protozoan, among others. Other topics covered include diagnosis, sensor and therapeutic applications, as well as ethical and regulatory issues. This book is a valuable source not only for beginners in genome engineering, but also researchers, clinicians, stakeholders, policy makers, and practitioners interested in the potential of CRISPR-Cas9 in several fields. Provides basic understanding and a clear picture on how to design, use and implement the CRISPR-Cas9 system in different organisms Explains how to create an animal model for disease research and screening purposes using CRISPR Discusses the application of CRISPR-Cas9 systems in basic sciences, biomedicine, virology, bacteriology, molecular biology, neurology, cancer, industry, and many more

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  • Author : Vijai Singh
  • Publisher : Academic Press
  • Pages : 384 pages
  • ISBN : 0128181419
  • Rating : 4/5 from 21 reviews
CLICK HERE TO GET THIS BOOKGenome Engineering via CRISPR Cas9 System

Genome Engineering via CRISPR-Cas9 System

Genome Engineering via CRISPR-Cas9 System
  • Author : Vijai Singh,Pawan K. Dhar
  • Publisher : Academic Press
  • Release : 18 February 2020
GET THIS BOOKGenome Engineering via CRISPR-Cas9 System

Genome Engineering via CRISPR-Cas9 Systems presents a compilation of chapters from eminent scientists from across the globe who have established expertise in working with CRISPR-Cas9 systems. Currently, targeted genome engineering is a key technology for basic science, biomedical and industrial applications due to the relative simplicity to which they can be designed, used and applied. However, it is not easy to find relevant information gathered in a single source. The book contains a wide range of applications of CRISPR in

Plant Genome Editing with CRISPR Systems

Plant Genome Editing with CRISPR Systems
  • Author : Yiping Qi
  • Publisher : Humana Press
  • Release : 19 February 2019
GET THIS BOOKPlant Genome Editing with CRISPR Systems

This volume provides readers with wide-ranging coverage of CRISPR systems and their applications in various plant species. The chapters in this book discuss topics such as plant DNA repair and genome editing; analysis of CRISPR-induced mutations; multiplexed CRISPR/Cas9 systems; CRISPR-Cas12a (Cpf1) editing systems; and non-agrobacterium based CRISPR delivery systems. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory

Human Genome Editing

Human Genome Editing
  • Author : National Academies of Sciences, Engineering, and Medicine,National Academy of Medicine,National Academy of Sciences,Committee on Human Gene Editing: Scientific, Medical, and Ethical Considerations
  • Publisher : National Academies Press
  • Release : 13 August 2017
GET THIS BOOKHuman Genome Editing

Genome editing is a powerful new tool for making precise alterations to an organism's genetic material. Recent scientific advances have made genome editing more efficient, precise, and flexible than ever before. These advances have spurred an explosion of interest from around the globe in the possible ways in which genome editing can improve human health. The speed at which these technologies are being developed and applied has led many policymakers and stakeholders to express concern about whether appropriate systems are

CRISPR-Cas Systems

CRISPR-Cas Systems
  • Author : Rodolphe Barrangou,John van der Oost
  • Publisher : Springer Science & Business Media
  • Release : 13 December 2012
GET THIS BOOKCRISPR-Cas Systems

CRISPR/Cas is a recently described defense system that protects bacteria and archaea against invasion by mobile genetic elements such as viruses and plasmids. A wide spectrum of distinct CRISPR/Cas systems has been identified in at least half of the available prokaryotic genomes. On-going structural and functional analyses have resulted in a far greater insight into the functions and possible applications of these systems, although many secrets remain to be discovered. In this book, experts summarize the state of

Chromosomal Mutagenesis

Chromosomal Mutagenesis
  • Author : Shondra M. Pruett-Miller
  • Publisher : Humana Press
  • Release : 22 September 2016
GET THIS BOOKChromosomal Mutagenesis

This new edition explores current and emerging mutagenesis methods focusing specifically on mammalian systems and commonly used model organisms through comprehensive coverage and detailed protocols. Since the first edition, major advances and discoveries have made chromosomal mutagenesis a widely used technique and one that is available to any molecular biology laboratory, and this collection provides detailed protocols, case-studies, and reviews from thought-leaders in the field. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to

Next Generation Plant Breeding

Next Generation Plant Breeding
  • Author : Yelda Ozden Çiftçi
  • Publisher : BoD – Books on Demand
  • Release : 26 September 2018
GET THIS BOOKNext Generation Plant Breeding

Following the green revolution and transgenic crop development, another revolutionary progress has been experienced in plant breeding in the last decade with the application of marker-assisted selection (MAS), next-generation sequencing (NGS), and gene editing techniques together with omic technologies, including genomics, transcriptomics, proteomics, and phenomics. Thus, this book is structured into two sections: "Marker-Assisted Breeding" and "RNA-seq and Gene Editing in Plants," which aim to provide a reference for students, instructors, and scientists on recent innovative advances in plant-breeding programs

Modern Prometheus

Modern Prometheus
  • Author : Jim Kozubek
  • Publisher : Cambridge University Press
  • Release : 26 April 2018
GET THIS BOOKModern Prometheus

This book tells the dramatic story of Crispr and the potential impact of this gene-editing technology.

Transgenic Animal Technology

Transgenic Animal Technology
  • Author : Carl A. Pinkert
  • Publisher : Newnes
  • Release : 17 June 2014
GET THIS BOOKTransgenic Animal Technology

Transgenic animal technologies and the ability to introduce functional genes into animals have revolutionized our ability to address complex biomedical and biological questions. This well-illustrated handbook covers the technical aspects of gene transfer — from molecular methods to whole animal considerations — for important laboratory and domestic animal species. It describes methodologies as employed by leading laboratories and is a key resource for researchers, as well as a tool for training technicians and students. This second edition incorporates updates on a variety

Targeted Genome Editing Using Site-Specific Nucleases

Targeted Genome Editing Using Site-Specific Nucleases
  • Author : Takashi Yamamoto
  • Publisher : Springer
  • Release : 05 January 2015
GET THIS BOOKTargeted Genome Editing Using Site-Specific Nucleases

This book serves as an introduction to targeted genome editing, beginning with the background of this rapidly developing field and methods for generation of engineered nucleases. Applications of genome editing tools are then described in detail, in iPS cells and diverse organisms such as mice, rats, marine invertebrates, fish, frogs, and plants. Tools that are mentioned include zinc finger nucleases (ZFNs), transcription activator-like effector nucleases (TALENs), and CRISPR/Cas9, all of which have received much attention in recent years as

Plant Genomes

Plant Genomes
  • Author : Jean-Nicolas Volff
  • Publisher : Karger Medical and Scientific Publishers
  • Release : 01 January 2008
GET THIS BOOKPlant Genomes

Recent major advances in the field of comparative genomics and cytogenomics of plants, particularly associated with the completion of ambitious genome projects, have uncovered astonishing facets of the architecture and evolutionary history of plant genomes. The aim of this book was to review these recent developments as well as their implications in our understanding of the mechanisms which drive plant diversity. New insights into the evolution of gene functions, gene families and genome size are presented, with particular emphasis on

Gene Editing

Gene Editing
  • Author : Yuan-Chuan Chen,Shiu-Jau Chen
  • Publisher : BoD – Books on Demand
  • Release : 29 May 2019
GET THIS BOOKGene Editing

Gene-editing technologies (e.g., ZFNs, TALENs, and CRISPRs/Cas9) have been extensively used as tools in basic research. They are further applied in manufacturing agricultural products, food, industrial products, medicinal products, etc. Particularly, the discovery of medicinal products using gene-editing technologies will open a new era for human therapeutics. Though there are still many technical and ethical challenges ahead of us, more and more products based on gene-editing technologies have been approved for marketing. These technologies are promising for multiple

CRISPR Gene Editing

CRISPR Gene Editing
  • Author : Yonglun Luo
  • Publisher : Unknown Publisher
  • Release : 07 March 2021
GET THIS BOOKCRISPR Gene Editing

This detailed volume guides readers through strategic planning and user-friendly guidelines in order to select the most suitable CRISPR-Cas system and target sites with high activity and specificity. Methods covering CRISPR gRNA design, CRISPR delivery, CRISPR activity quantification (indel quantification), and examples of applying CRISPR gene editing in human pluripotent stem cells, primary cells, gene therapy, and genetic screening are included. Written for the highly successful Methods in Molecular Biology series, chapters include introductions to their respective topics, lists of

Chromosome and Genomic Engineering in Plants

Chromosome and Genomic Engineering in Plants
  • Author : Minoru Murata
  • Publisher : Humana Press
  • Release : 25 August 2016
GET THIS BOOKChromosome and Genomic Engineering in Plants

This volume assembles protocols for chromosome engineering and genome editing in two recently developed approaches for manipulating chromosomal and genomic DNA in plants. The first approach is a “plant chromosome vector” system, which allows the introduction of desired genes or DNA into target sites on the chromosome vector, particularly by sequence-specific recombination. The second approach is “genome-editing,” which makes it possible to introduce mutations into any of the genes of DNA that we wish to change. In addition, this book