Clinical Genomics

Clinical Genomics provides an overview of the various next-generation sequencing (NGS) technologies that are currently used in clinical diagnostic laboratories. It presents key bioinformatic challenges and the solutions that must be addressed by clinical genomicists and genomic pathologists, such as specific pipelines for identification of the full range of variants that are clinically important. This book is also focused on the challenges of diagnostic interpretation of NGS results in a clinical setting. Its final sections are devoted to the emerging regulatory issues that will govern clinical use of NGS, and reimbursement paradigms that will affect the way in which laboratory professionals get paid for the testing. Simplifies complexities of NGS technologies for rapid education of clinical genomicists and genomic pathologists towards genomic medicine paradigm Tried and tested practice-based analysis for precision diagnosis and treatment plans Specific pipelines and meta-analysis for full range of clinically important variants

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  • Author : Shashikant Kulkarni
  • Publisher : Academic Press
  • Pages : 488 pages
  • ISBN : 0124051731
  • Rating : 4/5 from 21 reviews
CLICK HERE TO GET THIS BOOKClinical Genomics

Clinical Genomics

Clinical Genomics
  • Author : Shashikant Kulkarni,John Pfeifer
  • Publisher : Academic Press
  • Release : 10 November 2014
GET THIS BOOKClinical Genomics

Clinical Genomics provides an overview of the various next-generation sequencing (NGS) technologies that are currently used in clinical diagnostic laboratories. It presents key bioinformatic challenges and the solutions that must be addressed by clinical genomicists and genomic pathologists, such as specific pipelines for identification of the full range of variants that are clinically important. This book is also focused on the challenges of diagnostic interpretation of NGS results in a clinical setting. Its final sections are devoted to the emerging

Clinical Genome Sequencing

Clinical Genome Sequencing
  • Author : Aad Tibben,Barbara B. Biesecker
  • Publisher : Academic Press
  • Release : 30 March 2019
GET THIS BOOKClinical Genome Sequencing

Clinical Genome Sequencing: Psychological Aspects thoroughly details key psychological factors to consider while implementing genome sequencing in clinical practice, taking into account the subtleties of genetic risk assessment, patient consent and best practices for sharing genomic findings. Chapter contributions from leading international researchers and practitioners cover topics ranging from the current state of genomic testing, to patient consent, patient responses to sequencing data, common uncertainties, direct-to-consumer genomics, the role of genome sequencing in precision medicine, genetic counseling and genome sequencing,

Handbook of Clinical Adult Genetics and Genomics

Handbook of Clinical Adult Genetics and Genomics
  • Author : Shweta Dhar,Sandesh Sreenath Chakravarthy Nagamani,Tanya Eble
  • Publisher : Academic Press
  • Release : 10 April 2020
GET THIS BOOKHandbook of Clinical Adult Genetics and Genomics

Handbook of Clinical Adult Genetics and Genomics: A Practice-Based Approach provides a thorough overview of genetic disorders that are commonly encountered in adult populations and supports the full translation of adult genetic and genomic modalities into clinical practice. Expert chapter authors supplement foundational knowledge with case-based strategies for the evaluation and management of genetic disorders in each organ system and specialty area. Topics discussed include employing genetic testing technologies, reporting test results, genetic counseling for adult patients, medical genetics referrals,

Genomics in the Clinic

Genomics in the Clinic
  • Author : Ethylin Wang Jabs,Antonie D. Kline
  • Publisher : Academic Press
  • Release : 01 June 2020
GET THIS BOOKGenomics in the Clinic

Genomics to the Clinic: A Practical Guide to Genetic Testing, Evaluation, and Counseling clearly explains central concepts of clinical genomic medicine and testing for non-geneticist clinicians and healthcare affiliates of various types, including pediatricians, internists, general practitioners, family medicine doctors, obstetricians and gynecologists, oncologists and pharmacists. Readers will learn to make appropriate genetic referrals, prepare patients for genetic consultation and testing results, understand basic genetic testing methods and nomenclature, and become versed in the ethical, legal and psychosocial aspects of

Genomic and Personalized Medicine

Genomic and Personalized Medicine
  • Author : Anonim
  • Publisher : Academic Press
  • Release : 30 October 2012
GET THIS BOOKGenomic and Personalized Medicine

Genomic and Personalized Medicine, Second Edition — winner of a 2013 Highly Commended BMA Medical Book Award for Medicine — is a major discussion of the structure, history, and applications of the field, as it emerges from the campus and lab into clinical action. As with the first edition, leading experts review the development of the new science, the current opportunities for genome-based analysis in healthcare, and the potential of genomic medicine in future healthcare. The inclusion of the latest information on diagnostic

Genomic Medicine

Genomic Medicine
  • Author : Dhavendra Kumar,Charis Eng
  • Publisher : Oxford University Press (UK)
  • Release : 01 March 2021
GET THIS BOOKGenomic Medicine

Preceded by Genomics and clinical medicine / edited by Dhavendra Kumar. [First edition]. 2008.

Clinical Precision Medicine

Clinical Precision Medicine
  • Author : Judy S. Crabtree
  • Publisher : Academic Press
  • Release : 15 November 2019
GET THIS BOOKClinical Precision Medicine

Clinical Precision Medicine: A Primer offers clinicians, researchers and students a practical, up-to-date resource on precision medicine, its evolving technologies, and pathways towards clinical implementation. Early chapters address the fundamentals of molecular biology and gene regulation as they relate to precision medicine, as well as the foundations of heredity and epigenetics. Oncology, an early adopter of precision approaches, is considered with its relationship to genetic variation in drug metabolism, along with tumor immunology and the impact of DNA variation in

Precision Medicine for Investigators, Practitioners and Providers

Precision Medicine for Investigators, Practitioners and Providers
  • Author : Joel Faintuch,Salomao Faintuch
  • Publisher : Academic Press
  • Release : 16 November 2019
GET THIS BOOKPrecision Medicine for Investigators, Practitioners and Providers

Precision Medicine for Investigators, Practitioners and Providers addresses the needs of investigators by covering the topic as an umbrella concept, from new drug trials to wearable diagnostic devices, and from pediatrics to psychiatry in a manner that is up-to-date and authoritative. Sections include broad coverage of concerning disease groups and ancillary information about techniques, resources and consequences. Moreover, each chapter follows a structured blueprint, so that multiple, essential items are not overlooked. Instead of simply concentrating on a limited number

Advancing Healthcare Through Personalized Medicine

Advancing Healthcare Through Personalized Medicine
  • Author : Priya Hays
  • Publisher : CRC Press
  • Release : 24 February 2017
GET THIS BOOKAdvancing Healthcare Through Personalized Medicine

This innovative book provides a unique perspective on the biomedical and societal implications of personalized medicine and how it will help mitigate the healthcare crisis and rein in ever-growing expenditure. It introduces the reader to underlying concepts at the heart of personalized medicine - pharmacogenomics, targeted therapies and individualized diagnosis and treatment - and shows how, with the advent of genomic technologies, clinicians will have the capability to predict and diagnose disease more efficiently. Advocating a patient-centred approach at the

Cardiovascular Genetics and Genomics in Clinical Practice

Cardiovascular Genetics and Genomics in Clinical Practice
  • Author : Donna K. Arnett, PhD,Sanjiv J. Shah, MD
  • Publisher : Demos Medical Publishing
  • Release : 10 November 2014
GET THIS BOOKCardiovascular Genetics and Genomics in Clinical Practice

Weighted Numerical Score: 100 - 5 Stars! This is a systematic guide to cardiovascular genetics and genomics from basic concepts to clinical application. It organizes a large volume of information from an active area of research, which holds promise for future discovery. --Doody's Reviews Cardiovascular Genetics and Genomics in Clinical Practice presents clinical cases to illuminate basic concepts of cardiovascular genetics and genomics as practitioners encounter them in day-to-day practice. The unique use of real-world case discussions facilitates the memorization and understanding

Evaluation of User Satisfaction with a Clinical Genetics Database

Evaluation of User Satisfaction with a Clinical Genetics Database
  • Author : Ferry Oriyo
  • Publisher : Unknown Publisher
  • Release : 01 March 2021
GET THIS BOOKEvaluation of User Satisfaction with a Clinical Genetics Database

Abstract: Fulfilling the personalized medicine ideal involves capturing detailed data on the genomics, genetics and family history of an individual. Recording this information challenges existing patient record systems. Consequently, The Ohio State University's Clinical Cancer Genetics and Medical Genetics program (CCG) developed a comprehensive database to serve as a repository for the program's clinic and research data. Since inception, the application has not undergone any formal evaluation. To ensure the database meets user needs and to identify where improvements and

Genomics, Circuits, and Pathways in Clinical Neuropsychiatry

Genomics, Circuits, and Pathways in Clinical Neuropsychiatry
  • Author : Thomas Lehner,Bruce L. Miller,Matthew W. State
  • Publisher : Academic Press
  • Release : 07 June 2016
GET THIS BOOKGenomics, Circuits, and Pathways in Clinical Neuropsychiatry

This foundational work comprehensively examines the current state of the genetics, genomics and brain circuitry of psychiatric and neurological disorders. It consolidates discoveries of specific genes and genomic regions associated with these conditions, the genetic and anatomic architecture of these syndromes, and addresses how recent advances in genomics are leading to a reappraisal of the biology underlying clinical neuroscience. In doing so, it critically examines the promise and limitations of these discoveries toward treatment, and to the interdisciplinary nature of

Genomic Medicine in Emerging Economies

Genomic Medicine in Emerging Economies
  • Author : George Patrinos,Catalina Lopez-Correa
  • Publisher : Academic Press
  • Release : 29 June 2018
GET THIS BOOKGenomic Medicine in Emerging Economies

Genomic Medicine in Resource-limited Countries: Genomics for Every Nation provides in-depth analysis and key examples of the implementation of medical genomics in low-income nations across the globe, demonstrating how this advancing medical science has not only transformed health systems, but also led to improved patient care in Indonesian, Nepalese, Chilean, Malaysian, Tanzanian, Argentinian, Chinese, Sri Lankan and Columbian populations, among others. In addition to defining tools, diagnostics and treatment pathways at the population-wide level for medical geneticists, genomic researchers and

Economic Evaluation in Genomic Medicine

Economic Evaluation in Genomic Medicine
  • Author : Vasilios Fragoulakis,Christina Mitropoulou,Marc Williams,George P. Patrinos
  • Publisher : Academic Press
  • Release : 20 March 2015
GET THIS BOOKEconomic Evaluation in Genomic Medicine

Economic Evaluation in Genomic Medicine introduces health economics and economic evaluation to genomic clinicians and researchers, while also introducing the topic to health economists. Each chapter includes an executive summary, questions, and case studies, along with supplementary online materials, including process guides, maps, flow charts, diagrams, and economic evaluation spreadsheets to enhance the learning process. The text can easily be used as course material for related graduate and undergraduate courses, providing a succinct overview of the existing, state-of-the-art application of

Progress and Challenges in Precision Medicine

Progress and Challenges in Precision Medicine
  • Author : Mukesh Verma,Debmalya Barh
  • Publisher : Academic Press
  • Release : 22 December 2016
GET THIS BOOKProgress and Challenges in Precision Medicine

Progress and Challenges in Precision Medicine presents an insightful overview to the myriad factors of personalized and precision medicine. The availability of the human genome, large amounts of data on individual genetic variations, environmental interactions, influence of lifestyle, and cutting-edge tools and technologies for big-data analysis have led to the age of personalized and precision medicine. Bringing together a global range of experts on precision medicine, this book collects previously scattered information into one concise volume which covers the most