Glyceraldehyde 3 Phosphate Dehydrogenase GAPDH

Glyceraldehyde-3-Phosphate Dehydrogenase (GAPDH): The Quintessential Moonlighting Protein in Normal Cell Function and in Human Disease examines the biochemical protein interactions of the multi-dimensional protein GAPDH, further considering the regulatory mechanisms through which cells control their functional diversity. This protein’s diverse activities range from nuclear tRNA export and the maintenance of genomic integrity, to cytoplasmic post-transcriptional control of gene expression and receptor mediated cell signaling, to membrane facilitation of iron metabolism, trafficking and fusion. This book will be of great interest to basic scientists, clinicians and students, including molecular and cell biologists, immunologists, pathologists and clinical researchers who are interested in the biochemistry of GAPDH in health and disease. Contextualizes how GAPDH is utilized by cells in vivo Provides detailed insight into GAPDH post-translational modifications, including functional diversity and its subcellular localization Includes forward-thinking exposition on tough topics, such as the exploration of how GAPDG performs functions, how it decides where it should be present and requisite structural requirements

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  • Author : Michael A. Sirover
  • Publisher : Academic Press
  • Pages : 324 pages
  • ISBN : 0128098988
  • Rating : 4/5 from 21 reviews
CLICK HERE TO GET THIS BOOKGlyceraldehyde 3 Phosphate Dehydrogenase GAPDH

Glyceraldehyde-3-Phosphate Dehydrogenase (GAPDH)

Glyceraldehyde-3-Phosphate Dehydrogenase (GAPDH)
  • Author : Michael A. Sirover
  • Publisher : Academic Press
  • Release : 22 May 2017
GET THIS BOOKGlyceraldehyde-3-Phosphate Dehydrogenase (GAPDH)

Glyceraldehyde-3-Phosphate Dehydrogenase (GAPDH): The Quintessential Moonlighting Protein in Normal Cell Function and in Human Disease examines the biochemical protein interactions of the multi-dimensional protein GAPDH, further considering the regulatory mechanisms through which cells control their functional diversity. This protein’s diverse activities range from nuclear tRNA export and the maintenance of genomic integrity, to cytoplasmic post-transcriptional control of gene expression and receptor mediated cell signaling, to membrane facilitation of iron metabolism, trafficking and fusion. This book will be of

Glyceraldehyde-3-Phosphate Dehydrogenase (GAPDH)

Glyceraldehyde-3-Phosphate Dehydrogenase (GAPDH)
  • Author : Michael A. Sirover
  • Publisher : Academic Press
  • Release : 05 June 2017
GET THIS BOOKGlyceraldehyde-3-Phosphate Dehydrogenase (GAPDH)

Glyceraldehyde-3-Phosphate Dehydrogenase (GAPDH): The Quintessential Moonlighting Protein in Normal Cell Function and in Human Disease examines the biochemical protein interactions of the multi-dimensional protein GAPDH, further considering the regulatory mechanisms through which cells control their functional diversity. This protein's diverse activities range from nuclear tRNA export and the maintenance of genomic integrity, to cytoplasmic post-transcriptional control of gene expression and receptor mediated cell signaling, to membrane facilitation of iron metabolism, trafficking and fusion. This book will be of great

Macromolecular Protein Complexes

Macromolecular Protein Complexes
  • Author : J. Robin Harris,Jon Marles-Wright
  • Publisher : Springer
  • Release : 07 March 2017
GET THIS BOOKMacromolecular Protein Complexes

This volume of the established Subcellular Biochemistry series presents 20 chapters dealing with a broad range of interesting protein complexes. It will enable researchers to readily appreciate the major contribution from both X-ray crystallography and cryo-electron microscopy in this field of study. The biological significance of these structural studies is emphasised throughout the book. The diversity of the material included here indicates the breadth of this field and the tremendous progress that has been made in recent years. The book is

GAPDH: Biological Properties and Diversity

GAPDH: Biological Properties and Diversity
  • Author : Norbert W. Seidler
  • Publisher : Springer Science & Business Media
  • Release : 31 July 2012
GET THIS BOOKGAPDH: Biological Properties and Diversity

The book represents a comprehensive review and synthesis of the biomedical literature that spans over a half-century on a single protein called glyceraldehyde 3-phosphate dehydrogenase (or, GAPDH). Due to the protein’s involvement in a vast array of cellular activities, GAPDH is of interest to the cell biologist, immunologist, virologist, biochemist etc. The protein has a significant role in fertility, cancer and neurodegeneration, suggesting that this book can be a vital resource for drug development. GAPDH function may provide insight

Biochemistry for Medical Professionals

Biochemistry for Medical Professionals
  • Author : Tsugikazu Komoda,Toshiyuki Matsunaga
  • Publisher : Academic Press
  • Release : 25 June 2015
GET THIS BOOKBiochemistry for Medical Professionals

Biochemistry for Medical Professionals contains pivotal advances in the biochemistry field and provides a resource for professionals across medicine, dentistry, pharmaceutical sciences and health professions who need a concise, topical biochemistry reference. Relevant, well-illustrated coverage begins with the composition of the human body and then goes into the technical detail of the metabolism of the human body and biochemistry of internal organs before featuring a biotechnology study inclusive of numerous methods and applications. The work is written at a consistently

Methods of Enzymatic Analysis

Methods of Enzymatic Analysis
  • Author : Hans-UIrich Bergmeyer
  • Publisher : Elsevier
  • Release : 02 December 2012
GET THIS BOOKMethods of Enzymatic Analysis

Methods of Enzymatic Analysis focuses on the general progress in enzymology and in the special field of enzymatic analysis. This book explores the commercial production of biochemical reagents for analysis and explains the transition from the possible use of enzymatic analysis to its various applications in pure and applied biochemistry. Organized into four sections, this book starts with an overview of the basis of enzymatic analysis and provides general experimental guidelines for the techniques of measurement and for the disintegration

Pyridine Nucleotide-Dependent Dehydrogenases

Pyridine Nucleotide-Dependent Dehydrogenases
  • Author : Horst Sund
  • Publisher : Springer Science & Business Media
  • Release : 06 December 2012
GET THIS BOOKPyridine Nucleotide-Dependent Dehydrogenases

The present volume represents the proceedings of the symposium on npyridine Nucleotide-Dependent Dehydrogenases" which was held on the campus of the re cently established University of Konstanz, Germany, from September 15 to 20, 1969. The aim of the symposium was to provide a forum for discussion among the experts interested in the various aspects of pyridine nucleotide-dependent de hydrogenases and the pyridine coenzymes, so as to evaluate the state of the present knowledge and to stimulate further progress in this field. In order

Advances in GAPDH Protein Analysis: A Functional and Biochemical Approach

Advances in GAPDH Protein Analysis: A Functional and Biochemical Approach
  • Author : Shanmugasundaram Ganapathy-Kanniappan
  • Publisher : Springer
  • Release : 16 January 2018
GET THIS BOOKAdvances in GAPDH Protein Analysis: A Functional and Biochemical Approach

This book presents modern and classic analytical approaches that are crucial for the biochemical and functional characterization of the archetypal protein, glyceraldehyde-3-phosphate dehydrogenase (GAPDH). The distinguishing feature of the book is that it covers, in addition to other methods, some of the uncommon but valuable techniques as well. For example, in-gel visualization of enzyme activity, immunoblotting protocols for native (non-denatured) proteins, and proteins resolved by pH-gradient [IEF-isoelectrofocusing], etc. These expedient methods are relevant and vital for the verification of

Sulfhydryl and Disulfide Groups of Proteins

Sulfhydryl and Disulfide Groups of Proteins
  • Author : Yu M. Torchinskii
  • Publisher : Springer Science & Business Media
  • Release : 22 November 2013
GET THIS BOOKSulfhydryl and Disulfide Groups of Proteins

(Written for the original Russian edition) Out of all the functional groups of protein molecules that be long to the side chains of amino acid residues, the sulfhydryl or thiol (SH) groups of cysteine residues and the disulfide (S-S) groups of cystine have for long attracted particular attention from chemists and biochemists. This is due, on the one hand, to the high chemical reactivity of these groups, which enter into many, and often very characteristic and selective, reactions with several

Biochemistry

Biochemistry
  • Author : Donald Voet,Judith G. Voet
  • Publisher : John Wiley & Sons Incorporated
  • Release : 09 March 2004
GET THIS BOOKBiochemistry

CD-ROM includes computer animated interactive exercizes, guided explorations, and color images.

Allosteric Enzymes

Allosteric Enzymes
  • Author : Guy Herve
  • Publisher : CRC Press
  • Release : 25 November 2020
GET THIS BOOKAllosteric Enzymes

This book compiles detailed information concerning a dozen of the best known allosteric enzymes, and so allows the comparison of their regulatory mechanisms and the confrontation of these mechanisms with the theoretical models. Stimulating and unexpected ideas emerge from these comparisons and emphasize the importance of developing various methods of investigation such as crystallography, X-ray solution scattering, and the study of fast movements in proteins and site-directed mutagenesis. This book is addressed to students and researchers interested in structure-function relationship

Essentials of Medical Biochemistry

Essentials of Medical Biochemistry
  • Author : Chung-Eun Ha,N. V. Bhagavan
  • Publisher : Academic Press
  • Release : 28 January 2011
GET THIS BOOKEssentials of Medical Biochemistry

Expert biochemist N.V. Bhagavan’s new work condenses his successful Medical Biochemistry texts along with numerous case studies, to act as an extensive review and reference guide for both students and experts alike. The research-driven content includes four-color illustrations throughout to develop an understanding of the events and processes that are occurring at both the molecular and macrolecular levels of physiologic regulation, clinical effects, and interactions. Using thorough introductions, end of chapter reviews, fact-filled tables, and related multiple-choice questions,

Moonlighting Proteins

Moonlighting Proteins
  • Author : Brian Henderson
  • Publisher : John Wiley & Sons
  • Release : 14 March 2017
GET THIS BOOKMoonlighting Proteins

Moonlighting Proteins: Novel Virulence Factors in Bacterial Infections is a complete examination of the ways in which proteins with more than one unique biological action are able to serve as virulence factors in different bacteria. The book explores the pathogenicity of bacterial moonlighting proteins, demonstrating the plasticity of protein evolution as it relates to protein function and to bacterial communication. Highlighting the latest discoveries in the field, it details the approximately 70 known bacterial proteins with a moonlighting function related to