Growth Factors and Their Receptors in Cell Differentiation Cancer and Cancer Therapy

Recent years have seen a considerable emphasis on growth factors and the elucidation of their mode of function, which has led to the recognition that growth factors, their receptors as well as downstream elements of signalling associated with their function might be potential targets in therapeutic management of human diseases. Humanised monoclonal antibodies raised against growth factor receptors have proved to be valuable for targeted cancer treatment and in patient management. This book reviews the latest developments providing insights into the signalling processes involved in morphogenesis and pathogenesis with emphasis on using the elements of the signalling cascades as targets for therapeutic deployment. Provides a fundamental understanding of the basic functions of growth factors and their receptors, describing how they are linked in biological processes Aids the development of therapeutic treatments for cancer Focuses on the interrelationships and convergence of growth factors and their receptors in development and pathogenesis and encourages greater cooperation and integration in the areas of developmental, cancer and cancer therapeutic research

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  • Author : G V Sherbet
  • Publisher : Elsevier
  • Pages : 368 pages
  • ISBN : 0123878209
  • Rating : 4/5 from 21 reviews
CLICK HERE TO GET THIS BOOKGrowth Factors and Their Receptors in Cell Differentiation Cancer and Cancer Therapy

Growth Factors and Their Receptors in Cell Differentiation, Cancer and Cancer Therapy

Growth Factors and Their Receptors in Cell Differentiation, Cancer and Cancer Therapy
  • Author : G V Sherbet
  • Publisher : Elsevier
  • Release : 12 July 2011
GET THIS BOOKGrowth Factors and Their Receptors in Cell Differentiation, Cancer and Cancer Therapy

Recent years have seen a considerable emphasis on growth factors and the elucidation of their mode of function, which has led to the recognition that growth factors, their receptors as well as downstream elements of signalling associated with their function might be potential targets in therapeutic management of human diseases. Humanised monoclonal antibodies raised against growth factor receptors have proved to be valuable for targeted cancer treatment and in patient management. This book reviews the latest developments providing insights into

Growth Factors and Their Receptors in Cell Differentiation, Cancer and Cancer Therapy

Growth Factors and Their Receptors in Cell Differentiation, Cancer and Cancer Therapy
  • Author : G V Sherbet
  • Publisher : Elsevier
  • Release : 12 July 2011
GET THIS BOOKGrowth Factors and Their Receptors in Cell Differentiation, Cancer and Cancer Therapy

Recent years have seen a considerable emphasis on growth factors and the elucidation of their mode of function, which has led to the recognition that growth factors, their receptors as well as downstream elements of signalling associated with their function might be potential targets in therapeutic management of human diseases. Humanised monoclonal antibodies raised against growth factor receptors have proved to be valuable for targeted cancer treatment and in patient management. This book reviews the latest developments providing insights into

Therapeutic Strategies in Cancer Biology and Pathology

Therapeutic Strategies in Cancer Biology and Pathology
  • Author : Gajanan V. Sherbet
  • Publisher : Elsevier
  • Release : 26 July 2013
GET THIS BOOKTherapeutic Strategies in Cancer Biology and Pathology

Currently, intensive effort is being directed toward the identification of molecular targets that can provide approaches to the development of novel therapeutic strategies in cancer management. This book focuses on metastasis-associated genes, metastasis promoter and suppressor genes, which relate specifically to behavioral alterations of cancer cells in epithelial mesenchymal transition, cancer stem cell maintenance and propagation, and to the acquisition of invasive and metastasis faculty. The function of these genes has implications for cell cycle regulation and cell proliferation and

Differentiation and Neoplasia

Differentiation and Neoplasia
  • Author : R. G. McKinnell,M. A. Diberardino,M. Blumenfeld,R. D. Bergad
  • Publisher : Springer Science & Business Media
  • Release : 09 March 2013
GET THIS BOOKDifferentiation and Neoplasia

There is no commonly accepted mechanism to explain differentiation of either normal or neoplastic cells. Despite this fact, the organizers of the 3 rd International Conference on Differentiation recognized that there is much emerging evidence which supports the view that both normal cells and many cancer cells share common differentiative processes. Accordingly, the organizers perceived that clinical scientists and developmental biologists would greatly benefit by together considering differentiation. In that way, developmental biologists would be apprised of recent insights in cancer

Cytokines and Cancer

Cytokines and Cancer
  • Author : Leonidas C. Platanias
  • Publisher : Springer Science & Business Media
  • Release : 04 March 2005
GET THIS BOOKCytokines and Cancer

The first book to cover both basic science and clinical research, providing a comprehensive review of the current knowledge on cytokines and cancer. Written by leading figures in the field of cytokine biology and cytokine therapeutics.

Signal Transduction in Cancer

Signal Transduction in Cancer
  • Author : David A. Frank
  • Publisher : Springer Science & Business Media
  • Release : 18 April 2006
GET THIS BOOKSignal Transduction in Cancer

One of the most exciting areas of cancer research now is the development of agents which can target signal transduction pathways that are activated inappropriately in malignant cells. The understanding of the molecular abnormalities which distinguish malignant cells from their normal counterparts has grown tremendously. This volume summarizes the current research on the role that signal transduction pathways play in the pathogenesis of cancer and how this knowledge may be used to develop the next generation of more effective and

The Biology of Cancer

The Biology of Cancer
  • Author : Weinberg, Robert A.
  • Publisher : W.W. Norton & Company
  • Release : 24 May 2013
GET THIS BOOKThe Biology of Cancer

Incorporating the most important advances in the fast-growing field of cancer biology, the text maintains all of its hallmark features. It is admired by students, instructors, researchers, and clinicians around the world for its clear writing, extensive full-color art program, and numerous pedagogical features.

Molecular Approach to Cancer Management

Molecular Approach to Cancer Management
  • Author : Gajanan V. Sherbet
  • Publisher : Academic Press
  • Release : 15 June 2017
GET THIS BOOKMolecular Approach to Cancer Management

Molecular Approach to Cancer Management discusses molecular mechanisms of cancer initiation, growth and secondary spread, emphasizing how this information can be used to devise new modes of treatment of cancer, especially in combatting secondary spread. The book addresses the basic concepts relating to cancer biology, the genetic determinants, and the signal transduction cascades associated with tumor growth, EMT, stem cell maintenance and propagation, and invasion and metastasis. The salient features of the signaling systems that are amenable to targeted manipulation

Breast Cancer and Surgery

Breast Cancer and Surgery
  • Author : Nilufer Bulut
  • Publisher : BoD – Books on Demand
  • Release : 21 November 2018
GET THIS BOOKBreast Cancer and Surgery

The book 'Breast Cancer and Surgery' summarizes the treatment options from the onset of breast carcinogenesis to early-local advanced and metastatic breast cancer. Chemotherapy alternatives, drug resistance and local and surgical treatment preferences are extensively discussed and this information is especially directed at clinicians, researchers, and students. This book includes a comparison between different chemotherapy agents and targeted therapies with published phase II-III studies. The importance of palliative care and dietary supplements administered during the treatment course in reducing the