Human Toxicology of Chemical Mixtures

In this important reference work, Zeliger catalogs the known effects of chemical mixtures on the human body and also proposes a framework for understanding and predicting their actions in terms of lipophile (fat soluble) / hydrophile (water soluble) interactions. The author’s focus is on illnesses that ensue following exposures to mixtures of chemicals that cannot be attributed to any one component of the mixture. In the first part the mechanisms of chemical absorption at a molecular and macromolecular level are explained, as well as the body’s methods of defending itself against xenobiotic intrusion. Part II examines the sources of the chemicals discusssed, looking at air and water pollution, food additives, pharmaceuticals, etc. Part III, which includes numerous case studies, examines specific effects of particular mixtures on particular body systems and organs and presents a theoretical framework for predicting what the effects of uncharacterized mixtures might be. Part IV covers regulatory requirements and the need to adjust recommended exposure levels for products containing mixtures. It also contains recommendations on how to limit exposure to mixtures in the products we use and on how to limit release of mixtures into the environment. Providing brief summaries of each mixture and its effects, Zeliger provides a comprehensive reference, a jumping off point for professionals (with extensive chapter bibliographies) and an introduction to the topic for those studying traditional toxicology. Addressing many inadequately understood illnesses and conditions such as asthma, infertility and cancer, it will also be of interest to health professionals, environmental scientists and lawyers. Presents a theoretical framework for predicting the effects of chemical mixtures for which no specific data exists (this predictive aspect is important due to the vast number of different potential chemical combinations - far too many to comprehensively catalog) A quick and convenient source of hard to come by data on the rapidly developing field of chemical mixtures, for groups including chemists and engineers, toxicologists, health professionals and environmental scientists New and updated material comprises over 30% of this timely new edition, which includes the latest research data alongside an expanded introduction to the science and art of predicting the toxicological properties of chemical mixtures

Produk Detail:

  • Author : Harold Zeliger
  • Publisher : William Andrew
  • Pages : 574 pages
  • ISBN : 9781437734645
  • Rating : 4/5 from 21 reviews
CLICK HERE TO GET THIS BOOKHuman Toxicology of Chemical Mixtures

Human Toxicology of Chemical Mixtures

Human Toxicology of Chemical Mixtures
  • Author : Harold Zeliger
  • Publisher : William Andrew
  • Release : 24 June 2011
GET THIS BOOKHuman Toxicology of Chemical Mixtures

In this important reference work, Zeliger catalogs the known effects of chemical mixtures on the human body and also proposes a framework for understanding and predicting their actions in terms of lipophile (fat soluble) / hydrophile (water soluble) interactions. The author’s focus is on illnesses that ensue following exposures to mixtures of chemicals that cannot be attributed to any one component of the mixture. In the first part the mechanisms of chemical absorption at a molecular and macromolecular level are

Mixture Toxicity

Mixture Toxicity
  • Author : Cornelis A. M. van Gestel,Martijs Jonker,Jan E. Kammenga,Ryszard Laskowski,Claus Svendsen
  • Publisher : CRC Press
  • Release : 19 April 2016
GET THIS BOOKMixture Toxicity

In the last decade and a half, great progress has been made in the development of concepts and models for mixture toxicity, both in human and environmental toxicology. However, due to their different protection goals, developments have often progressed in parallel but with little integration. Arguably the first book to clearly link ecotoxicology and classic human toxicology, Mixture Toxicity: Linking Approaches from Ecological and Human Toxicology incorporates extensive reviews of exposure to toxicants, toxicokinetics and toxicodynamics, toxicity of mixtures, and

Toxicology of Chemical Mixtures

Toxicology of Chemical Mixtures
  • Author : Raymond S.H. Yang
  • Publisher : Elsevier
  • Release : 14 May 2016
GET THIS BOOKToxicology of Chemical Mixtures

Although toxicologic studies in the laboratory often focus on a single chemical, in the larger world, mixtures of chemicals are routinely encountered. Toxicology of Chemical Mixtures examines the mechanisms of interactions and health effects stemming from chemical mixtures in the environment. Toxicologists, pharmacologists, environmental scientists, and professionals involved in environmental clean-ups will benefit from its content. Emphasis is on low-level, long-term exposure. Key Features * Some of the issues addressed include: * Target organ toxicities in response to chemical mixture exposures * Risk

Chemical Mixtures and Combined Chemical and Nonchemical Stressors

Chemical Mixtures and Combined Chemical and Nonchemical Stressors
  • Author : Cynthia V. Rider,Jane Ellen Simmons
  • Publisher : Springer
  • Release : 16 February 2018
GET THIS BOOKChemical Mixtures and Combined Chemical and Nonchemical Stressors

In this book, both basic and advanced concepts are discussed for considering mixtures from initial exposure characterization through evaluation of risk associated with combined exposures. This book will provide an introduction to key issues and multiple options for evaluating both the toxicity of mixtures as well as the risk associated with exposure to mixtures. Additionally, promising tools adapted from other disciplines will be discussed in the context of mixtures toxicology and risk assessment. Finally, the discussion will move beyond chemical

Biomarkers in Toxicology

Biomarkers in Toxicology
  • Author : Ramesh C. Gupta
  • Publisher : Academic Press
  • Release : 13 February 2019
GET THIS BOOKBiomarkers in Toxicology

Biomarkers in Toxicology, Second Edition, is a timely and comprehensive reference dedicated to all aspects of biomarkers that relate to chemical exposure and their effects on biological systems. This revised and completely updated edition includes both vertebrate and non-vertebrate species models for toxicological testing and the development of biomarkers. Divided into several key sections, this reference volume contains new chapters devoted to topics in microplastics, neuroimmunotoxicity and nutraceuticals, along with a look at the latest cutting-edge technologies used to detect

Assessing the Human Health Risks of Trichloroethylene

Assessing the Human Health Risks of Trichloroethylene
  • Author : National Research Council,Division on Earth and Life Studies,Board on Environmental Studies and Toxicology,Committee on Human Health Risks of Trichloroethylene
  • Publisher : National Academies Press
  • Release : 08 January 2007
GET THIS BOOKAssessing the Human Health Risks of Trichloroethylene

Trichloroethylene is a chlorinated solvent widely used as a degreasing agent in industrial and manufacturing settings. It is also used as a chemical intermediate in making other chemicals and is a component of products such as typewriter correction fluid, paint removers, adhesives, and spot removers. In 2001, EPA issued a draft health risk assessment and proposed exposure standards for trichloroethylene. PA's Scientific Advisory Board (SAB) reviewed the draft and it was issued for public comment. A number of scientific issues were

Handbook of Toxicology of Chemical Warfare Agents

Handbook of Toxicology of Chemical Warfare Agents
  • Author : Ramesh C. Gupta
  • Publisher : Academic Press
  • Release : 02 April 2009
GET THIS BOOKHandbook of Toxicology of Chemical Warfare Agents

This groundbreaking book covers every aspect of deadly toxic chemicals used as weapons of mass destruction and employed in conflicts, warfare and terrorism. Including findings from experimental as well as clinical studies, this one-of-a-kind handbook is prepared in a very user- friendly format that can easily be followed by students, teachers and researchers, as well as lay people. Stand-alone chapters on individual chemicals and major topics allow the reader to easily access required information without searching through the entire book.

Handbook on the Toxicology of Metals: Specific metals

Handbook on the Toxicology of Metals: Specific metals
  • Author : Lars Friberg,Gunnar Nordberg,Velimir B. Vouk
  • Publisher : Elsevier Science Limited
  • Release : 14 April 1986
GET THIS BOOKHandbook on the Toxicology of Metals: Specific metals

Chapters on specific metals include physical and chemical properties, methods and problems of analysis, production and uses, environmental levels and exposures, metabolism, levels in tissues and biological fluids, effects and dose-response relationships, carcinogenicity, mutagenicity, teratogenicity and preventative measures, diagnosis, treatment and prognosis.

Toxicity and Hazard of Agrochemicals

Toxicity and Hazard of Agrochemicals
  • Author : Marcelo Larramendy,Sonia Soloneski
  • Publisher : BoD – Books on Demand
  • Release : 22 July 2015
GET THIS BOOKToxicity and Hazard of Agrochemicals

This edited book, Toxicity and Hazard of Agrochemicals, is intended to provide an overview of toxicology that examines the hazardous effects of common agrochemicals employed every day in our agricultural practices. Furthermore, it is hoped that the information in the present book will be of value to those directly engaged in the handling and use of agrochemicals and that this book will continue to meet the expectations and needs of all interested in the different aspects of human and environmental

Information Resources in Toxicology

Information Resources in Toxicology
  • Author : Steve Gilbert,Asish Mohapatra,Sol Bobst,Antoinette Hayes,Sara T. Humes
  • Publisher : Academic Press
  • Release : 15 May 2020
GET THIS BOOKInformation Resources in Toxicology

This new fifth edition of Information Resources in Toxicology offers a consolidated entry portal for the study, research, and practice of toxicology. Both volumes represents a unique, wide-ranging, curated, international, annotated bibliography, and directory of major resources in toxicology and allied fields such as environmental and occupational health, chemical safety, and risk assessment. The editors and authors are among the leaders of the profession sharing their cumulative wisdom in toxicology’s subdisciplines. This edition keeps pace with the digital world

Toxicology Studies

Toxicology Studies
  • Author : Ana Cristina Andreazza,Gustavo Scola
  • Publisher : BoD – Books on Demand
  • Release : 08 July 2015
GET THIS BOOKToxicology Studies

The increased exposure to toxins, toxicants and novel drugs has promoted toxicology to become one of the most important areas of research with emerging innovative toxicity testing protocols, techniques, and regulation being placed. Since the bioactivation of many toxins and toxicants and its consequences on human health are not clearly known, this book offers a quick overview of cellular toxicology through the cell, drug and environmental toxicity. This book does not strive to be comprehensive but instead offers a quick

Fish Physiology: Organic Chemical Toxicology of Fishes

Fish Physiology: Organic Chemical Toxicology of Fishes
  • Author : Keith B. Tierney,Anthony P. Farrell,Colin J. Brauner
  • Publisher : Academic Press
  • Release : 04 December 2013
GET THIS BOOKFish Physiology: Organic Chemical Toxicology of Fishes

Fish Physiology: Organic Chemical Toxicology of Fishes discusses the different types of organic chemical contaminants and their respective toxic effects in fish. The book also covers the detection of dissolved organic compounds and methods to assess organic toxicity. Substances addressed in this book include organometallics, hydrocarbons, endocrine disrupting compounds (EDCs), insecticides, herbicides, and pharmaceuticals. Fish are exposed to an ever-increasing array of organic chemicals that find their way into rivers and oceans. Some of these compounds are no longer being

Toxicology of Organophosphate and Carbamate Compounds

Toxicology of Organophosphate and Carbamate Compounds
  • Author : Ramesh C. Gupta
  • Publisher : Academic Press
  • Release : 28 April 2011
GET THIS BOOKToxicology of Organophosphate and Carbamate Compounds

This text/reference book provides the most comprehensive coverage of anticholinesterase compounds (Organophosphates and Carbamates), which constitute the largest number of chemicals that are primarily used as insecticides in agriculture, industry, and around the home/garden. Some OPs (nerve agents) have been used in chemical warfare and terrorist attacks, while some OPs and CMs have been recommended as therapeutic agents in human medicine as well as in veterinary medicine. Many chemicals of both classes are extremely toxic and lack selectivity,

Herbicides

Herbicides
  • Author : Andrew Price,Jessica Kelton
  • Publisher : BoD – Books on Demand
  • Release : 12 June 2013
GET THIS BOOKHerbicides

Herbicide use is a common component of many weed management strategies in both agricultural and non-crop settings. However, herbicide use practices and recommendations are continuously updated and revised to provide control of ever-changing weed compositions and to preserve efficacy of current weed control options. Herbicides - Current Research and Case Studies in Use provides information about current trends in herbicide use and weed control in different land and aquatic settings as well as case studies in particular weed control situations.

Globally Harmonized System of Classification and Labelling of Chemicals (GHS)

Globally Harmonized System of Classification and Labelling of Chemicals (GHS)
  • Author : United Nations Economic Commission for Europe
  • Publisher : United Nations
  • Release : 19 June 2015
GET THIS BOOKGlobally Harmonized System of Classification and Labelling of Chemicals (GHS)

The Globally Harmonized System of Classification and Labelling of Chemicals (GHS) addresses classification and labelling of chemicals by types of hazards. It provides the basis for worldwide harmonization of rules and regulations on chemicals and aims at enhancing the protection of human health and the environment during their handling, transport and use by ensuring that the information about their physical, health and environmental hazards is available. The sixth revised edition includes, inter alia, a new hazard class for desensitized explosives