Immunomodulatory Biomaterials

Biomaterials have existed for millennia as mechanical replacement structures following disease or injury. Biomaterial design has changed markedly from structural support with an “inert immune profile as the primary objective to designs that elicit an integrative local tissue response and a pro-repair immune cell phenotype. Immunomodulatory Biomaterials: Regulating the Immune Response with Biomaterials to Affect Clinical Outcome offers a single, comprehensive reference on biomaterials for modulation of the host response, for materials scientists, tissue engineers and those working in regenerative medicine. This book details methods, materials and strategies designed to regulate the host immune response following surgical implantation and thus facilitate specific local cell infiltration and tissue deposition. There has been a dramatic transformation in our understanding of the role of the immune system, both innate and adaptive; these changes include recognition of the plasticity of immune cells, especially macrophages, cross-talk between the immune system and stem cells, and the necessity for in situ transition between inflammatory and regulatory immune cell phenotypes. The exploitation of these findings and the design and manufacture of new biomaterials is occurring at an astounding pace. There is currently no book directed at the interdisciplinary principles guiding the design, manufacture, testing, and clinical translation of biomaterials that proactively regulate the host tissue immune response. The challenge for academia, industry, and regulatory agencies to encourage innovation while assuring safety and maximizing efficacy has never been greater. Given the highly interdisciplinary requirements for the design, manufacture and use of immunomodulatory biomaterials, this book will prove a useful single resource across disciplines. Holistically covers the design, manufacture, testing, and clinical translation of biomaterials that proactively regulate the host tissue immune response Provides a single reference for understanding and utilizing the host response in biomaterials design An international collaboration of leading researchers in the field offering a novel insight into this fast-growing area

Produk Detail:

  • Author : Stephen F. Badylak
  • Publisher : Woodhead Publishing
  • Pages : 294 pages
  • ISBN : 0128214562
  • Rating : 4/5 from 21 reviews
CLICK HERE TO GET THIS BOOKImmunomodulatory Biomaterials

Immunomodulatory Biomaterials

Immunomodulatory Biomaterials
  • Author : Stephen F. Badylak,Jennifer Elisseeff
  • Publisher : Woodhead Publishing
  • Release : 30 July 2021
GET THIS BOOKImmunomodulatory Biomaterials

Biomaterials have existed for millennia as mechanical replacement structures following disease or injury. Biomaterial design has changed markedly from structural support with an “inert immune profile as the primary objective to designs that elicit an integrative local tissue response and a pro-repair immune cell phenotype. Immunomodulatory Biomaterials: Regulating the Immune Response with Biomaterials to Affect Clinical Outcome offers a single, comprehensive reference on biomaterials for modulation of the host response, for materials scientists, tissue engineers and those working in regenerative

Immunomodulatory Biomaterials

Immunomodulatory Biomaterials
  • Author : Stephen F. Badylak,Jennifer Elisseeff
  • Publisher : Elsevier
  • Release : 19 August 2021
GET THIS BOOKImmunomodulatory Biomaterials

Biomaterials have existed for millennia as mechanical replacement structures following disease or injury. Biomaterial design has changed markedly from structural support with an "inert” immune profile as the primary objective to designs that elicit an integrative local tissue response and a pro-repair immune cell phenotype. Immunomodulatory Biomaterials: Regulating the Immune Response with Biomaterials to Affect Clinical Outcome offers a single, comprehensive reference on biomaterials for modulation of the host response, for materials scientists, tissue engineers and those working in regenerative

Biomaterials and Immune Response

Biomaterials and Immune Response
  • Author : Nihal Engin Vrana
  • Publisher : CRC Press
  • Release : 20 July 2018
GET THIS BOOKBiomaterials and Immune Response

The interactions of the biomaterials with the host immune system is crucial for their functionality. This book aims to provide the reader with a better understanding of the role of the immune system in biomaterial applications. For this end, the book has dedicated chapters for i) explaining immune cells taking part in immune response to biomaterials/immune systems interface; ii) the effect of biomaterial shape, form and physicochemical properties on the response of immune system; iii) biofilm formation on implanted

Biomaterials in Regenerative Medicine and the Immune System

Biomaterials in Regenerative Medicine and the Immune System
  • Author : Laura Santambrogio
  • Publisher : Springer
  • Release : 04 September 2015
GET THIS BOOKBiomaterials in Regenerative Medicine and the Immune System

The generation of tridimensional tissues, assembled from scaffolding materials populated with biologically functional cells, is the great challenge and hope of tissue bioengineering and regenerative medicine. The generation of biomaterials capable of harnessing the immune system has been particularly successful. This book provides a comprehensive view of how immune cells can be manipulated to suppresses inflammation, deliver vaccines, fight cancer cells, promote tissue regeneration or inhibit blood clotting and bacterial infections by functionally engineered biomaterials. However, long-lived polymers, such as

Cellular Response to Biomaterials

Cellular Response to Biomaterials
  • Author : Lucy Di Silvio
  • Publisher : Elsevier
  • Release : 22 December 2008
GET THIS BOOKCellular Response to Biomaterials

The response of cells to biomaterials is critical in medical devices. Traditionally inert biomaterials were used to minimise the reaction in cells in contact with the material. However, it has been realised that specific cell responses may be beneficial in such areas as encouraging adhesion, healing or cell multiplication. Cellular response to biomaterials discusses the response of cells to a wide range of biomaterials targeted at specific medical applications. Part one discusses cell responses to a variety of polymers and

Handbook of Biomaterials Biocompatibility

Handbook of Biomaterials Biocompatibility
  • Author : Masoud Mozafari
  • Publisher : Woodhead Publishing
  • Release : 17 June 2020
GET THIS BOOKHandbook of Biomaterials Biocompatibility

Handbook of Biomaterials Biocompatibility is a systematic reference on host response to different biomaterials, taking into account their physical, mechanical and chemical properties. The book reviews recent progress in the design and study of biomaterials biocompatibility, along with current understanding on how to control immune system response. Sections provide the fundamental theories and challenges of biomaterials biocompatibility, the role of different biomaterials physicochemical surface properties on cell responses, cell responses to different physicochemical properties of polymers, ceramics, metals, carbons and

Immunomodulatory Biomaterials to Mitigate Material-induced Host Responses

Immunomodulatory Biomaterials to Mitigate Material-induced Host Responses
  • Author : Yoon Kyung Kim
  • Publisher : Unknown Publisher
  • Release : 29 June 2022
GET THIS BOOKImmunomodulatory Biomaterials to Mitigate Material-induced Host Responses

The foreign body response to biomaterial implants has been a major challenge in translating many medical devices into the clinic. The presence of inflammatory cells around the implanted device prevents its functional interaction with the surrounding tissue, and although some inflammation may be desirable to mediate the healing process, a persistent inflammatory response will eventually lead to device failure. Significant efforts to reduce foreign body response have been largely focused on developing hydrophilic and anti-fouling coating materials, however, simply preventing

Tissue Engineering

Tissue Engineering
  • Author : Clemens Van Blitterswijk,Jan De Boer
  • Publisher : Academic Press
  • Release : 10 December 2014
GET THIS BOOKTissue Engineering

Tissue Engineering is a comprehensive introduction to the engineering and biological aspects of this critical subject. With contributions from internationally renowned authors, it provides a broad perspective on tissue engineering for students coming to the subject for the first time. In addition to the key topics covered in the previous edition, this update also includes new material on the regulatory authorities, commercial considerations as well as new chapters on microfabrication, materiomics and cell/biomaterial interface. Effectively reviews major foundational topics

Emerging Trends in Immunomodulatory Nanomaterials Toward Cancer Therapy

Emerging Trends in Immunomodulatory Nanomaterials Toward Cancer Therapy
  • Author : Anubhab Mukherjee,Vijay Sagar Madamsetty
  • Publisher : Springer Nature
  • Release : 31 May 2022
GET THIS BOOKEmerging Trends in Immunomodulatory Nanomaterials Toward Cancer Therapy

Recently, immunomodulatory nanomaterials have gained immense attention due to their involvement in the modulation of the body’s immune response to cancer therapy. This book highlights various immunomodulatory nanomaterials (including organic, polymer, inorganic, liposomes, viral, and protein nanoparticles) and their role in cancer therapy. Additionally, the mechanism of immunomodulation is reviewed in detail. Finally, the challenges of these therapies and their future outlook are discussed. We believe this book will be helpful to a broad community including students, researchers, educators,

Adverse Reactions to Biomaterials: State of the Art in Biomaterial Risk Assessment, Immunomodulation and In Vitro Models for Biomaterial Testing

Adverse Reactions to Biomaterials: State of the Art in Biomaterial Risk Assessment, Immunomodulation and In Vitro Models for Biomaterial Testing
  • Author : Nihal Engin Vrana,Amir M. Ghaemmaghami,Pinar Zorlutuna
  • Publisher : Frontiers Media SA
  • Release : 15 May 2019
GET THIS BOOKAdverse Reactions to Biomaterials: State of the Art in Biomaterial Risk Assessment, Immunomodulation and In Vitro Models for Biomaterial Testing

Adverse immune reactions to biomaterials are important bottlenecks for translation of novel biomaterials for clinical use. Moreover, recent advances in highthrough-put biomaterial discovery and synthetic biology, while providing exciting new veues, also significantly increases potential risks related to the in vivo reactions to these new materials. For example, the novel materials might have unintended biological activities due to their natural building blocks. In this perspective, biomaterial field needs i) better understanding of cell/biomaterial interactions at systems level; ii) development

The Immune Response to Implanted Materials and Devices

The Immune Response to Implanted Materials and Devices
  • Author : Bruna Corradetti
  • Publisher : Springer
  • Release : 30 November 2016
GET THIS BOOKThe Immune Response to Implanted Materials and Devices

This book provides a comprehensive overview of the cascade of events activated in the body following the implant of biomaterials and devices. It is one of the first books to shed light on the role of the host immune response on therapeutic efficacy, and reviews the state-of-the-art for both basic science and medical applications. The text examines advantages and disadvantages of the use of synthetic versus natural biomaterials. Particular emphasis is placed on the role of biomimicry in the development

Orthopedic Biomaterials

Orthopedic Biomaterials
  • Author : Bingyun Li,Thomas Webster
  • Publisher : Springer
  • Release : 17 August 2018
GET THIS BOOKOrthopedic Biomaterials

This book covers the latest progress in the biology and manufacturing of orthopedic biomaterials, as well as key industry perspectives. Topics covered include the development of biomaterial-based medical products for orthopedic applications, anti-infection technologies for orthopedic implants, additive manufacturing of orthopedic implants, and more. This is an ideal book for graduate students, researchers and professionals working with orthopedic biomaterials and tissue engineering. This book also: Provides an industry perspective on technologies to prevent orthopedic implant related infection Thoroughly covers how

Extracellular Vesicles

Extracellular Vesicles
  • Author : Dr Wojciech Chrzanowski,Professor Chwee Teck Lim,Dr Sally Yunsun Kim
  • Publisher : Royal Society of Chemistry
  • Release : 29 October 2021
GET THIS BOOKExtracellular Vesicles

Extracellular and biofluids vesicles (EVs) are highly specialised yet ubiquitous nanoscale messengers secreted by cells. With the development of stem cell engineering, EVs promise to deliver next generation tools in regenerative medicine and tissue engineering, as well as in diagnostics. A vibrant and promising field, this book provides the first resource to the field. Covering basic cell biology, including EV production and intracellular communication, this book will provide material scientists and engineers with a foundation to the necessary biology. The

Bioactive Materials for Bone Regeneration

Bioactive Materials for Bone Regeneration
  • Author : Jiang Chang,Xingdong Zhang,Kerong Dai
  • Publisher : Academic Press
  • Release : 28 February 2020
GET THIS BOOKBioactive Materials for Bone Regeneration

Bioactive Materials for Bone Regeneration summarizes research advances on the topic, including sections on the characteristics of biomaterial-induced microenvironments, interactions of bioactive materials with stem cells and tissues, and the immunomodulatory microenvironment induced by biomaterials and its effects on osteogenesis. As the regeneration of large-size bone tissue defects represents a significant clinical challenge, this book demonstrates how new biomaterials with specific chemical and physical characteristics may interact with the host and create a unique micro-environment that actively facilitates stem cell

Host Response to Biomaterials

Host Response to Biomaterials
  • Author : Stephen F Badylak
  • Publisher : Academic Press
  • Release : 08 May 2015
GET THIS BOOKHost Response to Biomaterials

Host Response to Biomaterials: The Impact of Host Response on Biomaterial Selection explains the various categories of biomaterials and their significance for clinical applications, focusing on the host response to each biomaterial. It is one of the first books to connect immunology and biomaterials with regard to host response. The text also explores the role of the immune system in host response, and covers the regulatory environment for biomaterials, along with the benefits of synthetic versus natural biomaterials, and the