Immunotherapeutic Strategies for the Treatment of Glioma

Immunotherapeutic Strategies for the Treatment of Glioma provides a review of the current state of immunotherapy for primary brain tumors. The topic is of interest to patients, clinicians, and researchers alike, particularly given the recent failure of large clinical trials. This book serves as an overview of the most promising approaches in the field and provides a foundation for considering novel and combination therapies moving forward. The book discusses several types of immunotherapies for glioma, such as peptide, dendritic cell and heat shock protein vaccines; immune checkpoint blockade; myeloid cells as target; oncolytic viruses; and CAR T cell therapy. Additionally, it discusses the mechanisms of immune suppression in patients and immunogenomics. This volume is a valuable source for cancer researchers, oncologists and several members of biomedical field who are interested in novel strategies to fight glioblastoma. Summarizes the work in immunotherapy for glioma to-date, including the available evidence from preclinical studies and clinical trials Reviews the challenges and successes of the most promising strategies for brain tumor immunotherapy Provides a foundation for considering novel and combination therapies moving forward

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  • Author : Christopher Jackson
  • Publisher : Academic Press
  • Pages : 250 pages
  • ISBN : 9780128197554
  • Rating : 4/5 from 21 reviews
CLICK HERE TO GET THIS BOOKImmunotherapeutic Strategies for the Treatment of Glioma

Immunotherapeutic Strategies for the Treatment of Glioma

Immunotherapeutic Strategies for the Treatment of Glioma
  • Author : Christopher Jackson,Michael Lim
  • Publisher : Academic Press
  • Release : 15 August 2021
GET THIS BOOKImmunotherapeutic Strategies for the Treatment of Glioma

Immunotherapeutic Strategies for the Treatment of Glioma provides a review of the current state of immunotherapy for primary brain tumors. The topic is of interest to patients, clinicians, and researchers alike, particularly given the recent failure of large clinical trials. This book serves as an overview of the most promising approaches in the field and provides a foundation for considering novel and combination therapies moving forward. The book discusses several types of immunotherapies for glioma, such as peptide, dendritic cell

Translational Immunotherapy of Brain Tumors

Translational Immunotherapy of Brain Tumors
  • Author : John H. Sampson
  • Publisher : Academic Press
  • Release : 06 February 2017
GET THIS BOOKTranslational Immunotherapy of Brain Tumors

Translational Immunotherapy of Brain Tumors gives researchers and practitioners an up-to-date and comprehensive overview of the field. Chapters include adoptive immunotherapy, immunosuppression, CAR therapy of brain tumors, and dendritic cell therapy for brain tumors. Very few agents have been shown to be efficacious in the treatment of malignant gliomas. Recently, there have been a number of studies demonstrating the potential success of immunotherapy for brain tumors. Immunotherapeutics are becoming the most frequent drugs to be used in cancer therapy. These

Glioma

Glioma
  • Author : ryuya yamanaka
  • Publisher : Springer Science & Business Media
  • Release : 27 May 2012
GET THIS BOOKGlioma

Treatment of glioma is currently one of the most challenging problems in oncology, as well as in neurosurgery. Despite major advances in our understanding of the pathomechanism, diagnosis by imaging and the availability of powerful therapeutic tools, the life expectancy of patients with glioblastoma has only been slightly prolonged and a cure remains elusive. None of the currently available surgical tools, including operative microscopes, lasers and image-guided surgery, can enable the detection and removal of all of the tumor tissue.

Glioblastoma:

Glioblastoma:
  • Author : Swapan K. Ray
  • Publisher : Springer Science & Business Media
  • Release : 31 October 2009
GET THIS BOOKGlioblastoma:

Glioblastoma is the most malignant brain tumor that still remains incurable. It is such a deadly disease that patients do not survive more than a few months after diagnosis. Our understanding of the histopathology and molecular mechanisms of formation of glioblastoma is rapidly advancing so as to provide us clues for devising rational therapeutic strategies for treatment of this malignancy. It is important that we continue to improve our knowledge about the pathogenesis of this devastating disease and explore new

Brain Tumor Immunotherapy

Brain Tumor Immunotherapy
  • Author : Linda M. Liau,Donald P. Becker,Timothy F. Cloughesy,Darell D. Bigner
  • Publisher : Springer Science & Business Media
  • Release : 10 November 2000
GET THIS BOOKBrain Tumor Immunotherapy

An authoritative panel of researchers and clinicians critically reviews the entire field to provide a comprehensive guide to modern brain tumor immunotherapy and thereby enhance future research in this area. The contributors detail many of the key laboratory experiments and clinical protocols that are currently being investigated, integrate the available information from previous and ongoing research, and help define the current status of the field. Topics range from adoptive cellular and antibody-mediated immunotherapy of brain tumors to tumor vaccines and

New Techniques for Management of ‘Inoperable’ Gliomas

New Techniques for Management of ‘Inoperable’ Gliomas
  • Author : Michael E. Sughrue,Isaac Yang
  • Publisher : Academic Press
  • Release : 03 August 2019
GET THIS BOOKNew Techniques for Management of ‘Inoperable’ Gliomas

New Techniques for Management of 'Inoperable' Gliomas radically challenges the assumption that certain gliomas cannot be removed with modern techniques, contesting stereotypical thinking and establishing new paradigms in the field. Gliomas are primary brain tumors which are often fatal. Recent data has demonstrated that despite the fact that surgery cannot cure gliomas, patient survival is substantially improved by removing as much of the tumor as possible. This fact has raised the imperative that neurologists try to improve techniques to bring

Intracranial Gliomas Part III - Innovative Treatment Modalities

Intracranial Gliomas Part III - Innovative Treatment Modalities
  • Author : M.F. Chernov,Y. Muragaki,S. Kesari,I.E. McCutcheon
  • Publisher : Karger Medical and Scientific Publishers
  • Release : 10 July 2018
GET THIS BOOKIntracranial Gliomas Part III - Innovative Treatment Modalities

At present most intracranial gliomas are considered incurable with current treatment strategies, and the search for new modalities that may effectively control tumor growth continues. The chapters in this volume describe basic principles and therapeutic possibilities of several innovative techniques, including photodynamic therapy, laser-induced interstitial thermotherapy, stereotactic cryodestruction, high-intensity focused ultrasound ablation, boron neutron capture therapy, proton and carbon ion irradiation, targeted therapy, immunotherapy, gene therapy, local chemotherapy, and alternating electric fields therapy. Potential applications of extracellular vesicles and nanotechnology

The Duke Glioma Handbook

The Duke Glioma Handbook
  • Author : Allan H. Friedman
  • Publisher : Cambridge University Press
  • Release : 31 March 2016
GET THIS BOOKThe Duke Glioma Handbook

Provides a summary of glioma biology, genetics and management, based on the world-leading Duke University Preston Robert Tisch Brain Tumor Center program.

Current Understanding and Treatment of Gliomas

Current Understanding and Treatment of Gliomas
  • Author : Jeffrey Raizer,Andrew Parsa
  • Publisher : Springer
  • Release : 02 December 2014
GET THIS BOOKCurrent Understanding and Treatment of Gliomas

This book reviews the significant advances in our understanding of glioma biology that have been achieved during the past decade and describes in detail the resultant new approaches to treatment. Improvements in surgical techniques, radiation therapy, and chemotherapy are comprehensively covered, with discussion of their impact in decreasing patient morbidity and increasing survival. In addition, individual chapters are devoted specifically to current treatment for low-grade gliomas, anaplastic gliomas, and glioblastoma multiforme. Other topics addressed include treatment of the elderly patient,

Keto for Cancer

Keto for Cancer
  • Author : Miriam Kalamian
  • Publisher : Chelsea Green Publishing
  • Release : 01 August 2021
GET THIS BOOKKeto for Cancer

A Comprehensive Guide for Patients and Practitioners Although evidence supporting the benefits of ketogenic diet therapies continues to mount, there is little to guide those who wish to adopt this diet as a metabolic therapy for cancer. Keto for Cancer fills this need. Inspired by the work of Dr. Thomas N. Seyfried, PhD, nutritionist Miriam Kalamian has written the first book to lay out comprehensive guidelines that specifically address the many challenges associated with cancer, and particularly the deep nutritional

Re-Irradiation: New Frontiers

Re-Irradiation: New Frontiers
  • Author : Carsten Nieder,Johannes Langendijk
  • Publisher : Springer
  • Release : 25 October 2016
GET THIS BOOKRe-Irradiation: New Frontiers

This book, now in its second edition, provides a comprehensive overview of current re-irradiation strategies, with detailed discussion of re-irradiation methods, technical aspects, the role of combined therapy with anticancer drugs and hyperthermia, and normal tissue tolerance. In addition, disease specific chapters document recent clinical results and future research directions. All chapters from the first edition have been revised and updated to take account of the latest developments and research findings, including those from prospective studies. Due attention is paid

Evolution of the Molecular Biology of Brain Tumors and the Therapeutic Implications

Evolution of the Molecular Biology of Brain Tumors and the Therapeutic Implications
  • Author : Terry Lichtor
  • Publisher : IntechOpen
  • Release : 27 February 2013
GET THIS BOOKEvolution of the Molecular Biology of Brain Tumors and the Therapeutic Implications

A dramatic increase in knowledge regarding the molecular biology of brain tumors has been established over the past few years. In particular recent new avenues regarding the role of stem cells and microRNAs along with further understanding of the importance of angiogenesis, immunotherapy and explanations for the resistance of the tumors to chemotherapeutic agents and radiation therapy has been developed. It is hopeful that this new information will lead to efficacious treatment strategies for these tumors which remain a challenge.

Glioma

Glioma
  • Author : Ibrahim Omerhodzic,Kenan Arnautovic
  • Publisher : BoD – Books on Demand
  • Release : 16 January 2019
GET THIS BOOKGlioma

The past three decades have been marked with huge enthusiasm from scientists and professionals in an effort to find a cure for glioma disease. Methods to confirm the kinds and grades of glioma have taken a path from classical macro- to microscopic pathohystological confirmation of tumors, through morphological-histological, molecular, and genetic diagnosis. Surgically, progress was made possible with the development and use of technological aids, for example neuronavigation, cortical mapping, electrocorticography, neuromonitoring, functional and intraoperative MRI, magnetoencephalography, etc. Great hope

Handbook of Brain Tumor Chemotherapy, Molecular Therapeutics, and Immunotherapy

Handbook of Brain Tumor Chemotherapy, Molecular Therapeutics, and Immunotherapy
  • Author : Herbert B. Newton
  • Publisher : Academic Press
  • Release : 28 March 2018
GET THIS BOOKHandbook of Brain Tumor Chemotherapy, Molecular Therapeutics, and Immunotherapy

Handbook of Brain Tumor Chemotherapy, Molecular Therapeutics, and Immunotherapy, Second Edition, provides a comprehensive overview of the molecular methodologies in the neuro-oncology field. There have been profound changes in the landscape of approaches to brain tumor therapy since the first edition—mainly in the areas of molecular biology and molecular therapeutics, as well as in the maturation of immunotherapy approaches (e.g., vaccines). This updated edition has a new, primary focus on multidisciplinary molecular methods, and is broadened to include

Cancer Immunotherapy: Mechanisms of Cancer Immunity, Engineering Immune- Based Therapies and Developing Clinical Trials

Cancer Immunotherapy: Mechanisms of Cancer Immunity, Engineering Immune- Based Therapies and Developing Clinical Trials
  • Author : Jianxun Song
  • Publisher : Bentham Science Publishers
  • Release : 16 April 2015
GET THIS BOOKCancer Immunotherapy: Mechanisms of Cancer Immunity, Engineering Immune- Based Therapies and Developing Clinical Trials

Clinicians, patients and scientists, alike, have been battling cancer for over several decades; however, patient outcomes have not significantly improved over the years with conventional therapies. In recent years, this has caused researchers to look for a change in the status quo, and, the awareness of the human immune system, which has an intrinsic mechanism to control microbial pathogens and dysfunctional self-tissues, has triggered scientists to look for new modes of cancer therapy. Cancer Immunotherapy has become a major research