Genome Editing Tools and Gene Drives

Genome editing methods are becoming routine tools for molecular and cell biologists. Such tools include ZFNs, CRISPR, megaTALs and TALENs. These tools are revolutionizing the creation of precisely manipulated genomes to modify the characteristics of organisms or cells. Additionally, gene drives have altered the way we understand inheritance laws. They give us the ability to have total control of the inheritance of traits of choice and importance. This succinct volume summarizes the history, principles, and applications - as well as the advantages and disadvantages - of each of these tools and various kinds of gene drives. The book is part of a program to produce books helpful to students and faculties of science at colleges and universities. This volume in the Pocket Guides to Biomedical Sciences series will help demystify these technologies. The book fills the gap between established conventional methods and the novel and exciting newly introduced tools of genome editing and gene drives. It will help young scientists understand the emerging genome editing tools and gene drives thereby promoting related research and adoption. Key Features The book extensively reviews the current genome editing tools and gene drives. Clarifies their targeting mechanisms and specificity of genome editing tools. Details many different types of natural and synthetic gene drives. Highlights concerns with gene drives and genome editing tools. Related Titles Brown, T. A. Genomes 4 (ISBN 978-0-8153-4508-4) Soh, J., et al. Genome Annotation (ISBN 978-1-4398-4117-4) Samuelsson, T. The Human Genome in Health and Disease: A Story in Four Letters (ISBN 978-0-8153-4591-6)

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  • Author : Reagan Mudziwapasi
  • Publisher : CRC Press
  • Pages : 152 pages
  • ISBN : 9780367760663
  • Rating : 4/5 from 21 reviews
CLICK HERE TO GET THIS BOOKGenome Editing Tools and Gene Drives

Genome Editing Tools and Gene Drives

Genome Editing Tools and Gene Drives
  • Author : Reagan Mudziwapasi,Taylor & Francis Group,Ringisai Chekera,Clophas Zibusiso Ncube,Irvonnie Shoko,Berlinda Ncube,Thandanani Moyo,Jeffrey Godfrey Chimbo,Jemethious Dube,Farai Faustos Mashiri,Moira Amanda Mubani,Duncan Maruta,Charity Chimbo,Mpumuzi Masuku,Ryman Shoko,Rutendo Patricia Nyamusamba,Fortune Ntengwa Jomane
  • Publisher : CRC Press
  • Release : 19 October 2021
GET THIS BOOKGenome Editing Tools and Gene Drives

Genome editing methods are becoming routine tools for molecular and cell biologists. Such tools include ZFNs, CRISPR, megaTALs and TALENs. These tools are revolutionizing the creation of precisely manipulated genomes to modify the characteristics of organisms or cells. Additionally, gene drives have altered the way we understand inheritance laws. They give us the ability to have total control of the inheritance of traits of choice and importance. This succinct volume summarizes the history, principles, and applications - as well as

Advances in Animal Genomics

Advances in Animal Genomics
  • Author : Sukanta Mondal,Ram Lakhan Singh
  • Publisher : Academic Press
  • Release : 25 November 2020
GET THIS BOOKAdvances in Animal Genomics

Advances in Animal Genomics provides an outstanding collection of integrated strategies involving traditional and modern - omics (structural, functional, comparative and epigenomics) approaches and genomics-assisted breeding methods which animal biotechnologists can utilize to dissect and decode the molecular and gene regulatory networks involved in the complex quantitative yield and stress tolerance traits in livestock. Written by international experts on animal genomics, this book explores the recent advances in high-throughput, next-generation whole genome and transcriptome sequencing, array-based genotyping, and modern bioinformatics

Targeted Genome Editing Using Site-Specific Nucleases

Targeted Genome Editing Using Site-Specific Nucleases
  • Author : Takashi Yamamoto
  • Publisher : Springer
  • Release : 05 January 2015
GET THIS BOOKTargeted Genome Editing Using Site-Specific Nucleases

This book serves as an introduction to targeted genome editing, beginning with the background of this rapidly developing field and methods for generation of engineered nucleases. Applications of genome editing tools are then described in detail, in iPS cells and diverse organisms such as mice, rats, marine invertebrates, fish, frogs, and plants. Tools that are mentioned include zinc finger nucleases (ZFNs), transcription activator-like effector nucleases (TALENs), and CRISPR/Cas9, all of which have received much attention in recent years as

Emerging Issues in Climate Smart Livestock Production

Emerging Issues in Climate Smart Livestock Production
  • Author : Sukanta Mondal,Ram Lakhan Singh
  • Publisher : Academic Press
  • Release : 15 December 2021
GET THIS BOOKEmerging Issues in Climate Smart Livestock Production

Emerging Issues in Climate Smart Livestock Production: Biological Tools and Techniques furnishes a detailed reference on livestock sustainability and the role of biotechnology for creating more sustainable livestock production systems. The book is a collection of scientific techniques, including genetic engineering used to modify and improve animals, fishes, and microorganisms for human benefit. The book is particularly attractive for scientists, researchers, students, educators, and professionals in agriculture, veterinary, and biotechnology science. This book promotes several biotechnological approaches that can easily

Animal Biotechnology 2

Animal Biotechnology 2
  • Author : Heiner Niemann,Christine Wrenzycki
  • Publisher : Springer
  • Release : 01 August 2018
GET THIS BOOKAnimal Biotechnology 2

This two-volume textbook provides a comprehensive overview on the broad field of Animal Biotechnology with a special focus on livestock reproduction and breeding. The reader will be introduced to a variety of state-of-the-art technologies and emerging genetic tools and their applications in animal production. Also, ethics and legal aspects of animal biotechnology will be discussed and new trends and developments in the field will be critically assessed. The two-volume work is a must-have for graduate students, advanced undergraduates and researchers

Gene Editing

Gene Editing
  • Author : Yuan-Chuan Chen,Shiu-Jau Chen
  • Publisher : BoD – Books on Demand
  • Release : 29 May 2019
GET THIS BOOKGene Editing

Gene-editing technologies (e.g., ZFNs, TALENs, and CRISPRs/Cas9) have been extensively used as tools in basic research. They are further applied in manufacturing agricultural products, food, industrial products, medicinal products, etc. Particularly, the discovery of medicinal products using gene-editing technologies will open a new era for human therapeutics. Though there are still many technical and ethical challenges ahead of us, more and more products based on gene-editing technologies have been approved for marketing. These technologies are promising for multiple

CRISPR-Cas Systems

CRISPR-Cas Systems
  • Author : Rodolphe Barrangou,John van der Oost
  • Publisher : Springer Science & Business Media
  • Release : 13 December 2012
GET THIS BOOKCRISPR-Cas Systems

CRISPR/Cas is a recently described defense system that protects bacteria and archaea against invasion by mobile genetic elements such as viruses and plasmids. A wide spectrum of distinct CRISPR/Cas systems has been identified in at least half of the available prokaryotic genomes. On-going structural and functional analyses have resulted in a far greater insight into the functions and possible applications of these systems, although many secrets remain to be discovered. In this book, experts summarize the state of

Genome Editing Tools and Gene Drives

Genome Editing Tools and Gene Drives
  • Author : Reagan Mudziwapasi,Ringisai Chekera,Clophas Zibusiso Ncube,Irvonnie Shoko,Berlinda Ncube,Thandanani Moyo,Jeffrey Godfrey Chimbo,Jemethious Dube,Farai Faustos Mashiri,Moira Amanda Mubani,Duncan Maruta,Charity Chimbo,Mpumuzi Masuku,Ryman Shoko,Rutendo Patricia Nyamusamba,Fortune Ntengwa Jomane
  • Publisher : CRC Press
  • Release : 19 October 2021
GET THIS BOOKGenome Editing Tools and Gene Drives

Genome-editing methods are becoming routine tools for molecular and cell biologists. Such tools include ZFNs, CRISPR, megaTALs and TALENs. These tools are revolutionizing the creation of precisely manipulated genomes to modify the characteristics of organisms or cells. Additionally, gene drives have altered the way we understand inheritance laws. They give us the ability to have total control of the inheritance of traits of choice and importance. This succinct volume summarizes the history, principles and applications – as well as the advantages

Viral Vectors for Gene Therapy

Viral Vectors for Gene Therapy
  • Author : Fredric P. Manfredsson,Matthew J. Benskey
  • Publisher : Unknown Publisher
  • Release : 21 May 2022
GET THIS BOOKViral Vectors for Gene Therapy

This volume discusses protocols, ranging from vector production to delivery methods, used to execute gene therapy applications. Chapters are divided into four parts, and cover topics such as design, construction, and application of transcription activation-like effectors; multi-modal production of adeno-associated virus; construction of oncolytic herpes simplex virus; AAV-mediated gene delivery to the mouse liver; and intrathecal delivery of gene therapeutics by direct lumbar puncture in mice. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions

Genome Editing in Animals

Genome Editing in Animals
  • Author : Izuho Hatada
  • Publisher : Humana Press
  • Release : 23 June 2017
GET THIS BOOKGenome Editing in Animals

This volume details protocols that can be used for generation of knockout animals. Chapters guide the reader through basic protocols for three genome editing technologies, target design tools, and specific protocols for each animal. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. Authoritative and practical, Genome Editing in Animals: Methods

Safety of Genetically Engineered Foods

Safety of Genetically Engineered Foods
  • Author : National Research Council,Institute of Medicine,Board on Agriculture and Natural Resources,Food and Nutrition Board,Board on Life Sciences,Committee on Identifying and Assessing Unintended Effects of Genetically Engineered Foods on Human Health
  • Publisher : National Academies Press
  • Release : 08 July 2004
GET THIS BOOKSafety of Genetically Engineered Foods

Assists policymakers in evaluating the appropriate scientific methods for detecting unintended changes in food and assessing the potential for adverse health effects from genetically modified products. In this book, the committee recommended that greater scrutiny should be given to foods containing new compounds or unusual amounts of naturally occurring substances, regardless of the method used to create them. The book offers a framework to guide federal agencies in selecting the route of safety assessment. It identifies and recommends several pre-

Transgenesis Techniques

Transgenesis Techniques
  • Author : Alan R. Clarke
  • Publisher : Springer Science & Business Media
  • Release : 21 May 2022
GET THIS BOOKTransgenesis Techniques

The past decade has witnessed a spectacular explosion in both the development and the use of transgenic technologies. In Transgenesis Techniques: Principles and Protocols, Second Edition, authoritative researchers-including members of the Dolly team-take stock of these exciting developments to present a collection of readily reproducible techniques for the generation and analysis of transgenic animals, focusing on the manipulation of the mammalian genome. This second edition devotes much space to the creation of genetically modified murine strains, providing access to the

Human Genome Editing

Human Genome Editing
  • Author : National Academies of Sciences, Engineering, and Medicine,National Academy of Medicine,National Academy of Sciences,Committee on Human Gene Editing: Scientific, Medical, and Ethical Considerations
  • Publisher : National Academies Press
  • Release : 13 August 2017
GET THIS BOOKHuman Genome Editing

Genome editing is a powerful new tool for making precise alterations to an organism's genetic material. Recent scientific advances have made genome editing more efficient, precise, and flexible than ever before. These advances have spurred an explosion of interest from around the globe in the possible ways in which genome editing can improve human health. The speed at which these technologies are being developed and applied has led many policymakers and stakeholders to express concern about whether appropriate systems are

Animal Genomics

Animal Genomics
  • Author : Bhanu P. Chowdhary
  • Publisher : S Karger Ag
  • Release : 21 May 2022
GET THIS BOOKAnimal Genomics

This publication provides an update on the current status of gene maps in different livestock and pet/companion animal species. The findings summarized in species specific commentaries and original articles testify the rapid advances made in the field of animal genomics. Of significant interest is the fact that current investigations are providing headways for two important and exciting research fronts: targeted high-resolution mapping leading to the application of genomic information in addressing questions of economic and biological significance in animals,

Heritable Human Genome Editing

Heritable Human Genome Editing
  • Author : The Royal Society,National Academy of Sciences,National Academy of Medicine,International Commission on the Clinical Use of Human Germline Genome Editing
  • Publisher : National Academies Press
  • Release : 16 January 2021
GET THIS BOOKHeritable Human Genome Editing

Heritable human genome editing - making changes to the genetic material of eggs, sperm, or any cells that lead to their development, including the cells of early embryos, and establishing a pregnancy - raises not only scientific and medical considerations but also a host of ethical, moral, and societal issues. Human embryos whose genomes have been edited should not be used to create a pregnancy until it is established that precise genomic changes can be made reliably and without introducing