Low Abundance Proteome Discovery

Low-Abundance Proteome Discovery addresses the most critical challenge in biomarker discovery and progress: the identification of low-abundance proteins. The book describes an original strategy developed by the authors that permits the detection of protein species typically found in very low abundance and that may yield valuable clues to future discoveries. Known as combinatorial peptide ligand libraries, these new methodologies are one of the hottest topics related to the study of proteomics and have applications in medical diagnostics, food quality, and plant analysis. The book is written for university and industry scientists starting proteomic studies of complex matrices (e.g., biological fluids, biopsies, recalcitrant plant tissues, foodstuff, and beverage analysis), researchers doing wet chemistry, and graduate-level students in the areas of analytical and biochemistry, biology, and genetics. Covers methodologies for enhancing the visibility of low-abundance proteins which, until now, has been the biggest challenge in biomarker progress Includes detailed protocols that address real-life needs in laboratory practice Addresses all applications, including human disease, food and beverage safety, and the discovery of new proteins/peptides of importance in nutraceutics Compiles the research and analytic protocols of the two scientists who are credited with the discovery of these landmark methodologies, also known as combinatorial peptide ligand libraries, for the identification of low-abundance proteins

Produk Detail:

  • Author : Egisto Boschetti
  • Publisher : Newnes
  • Pages : 364 pages
  • ISBN : 0124045960
  • Rating : 5/5 from 1 reviews
CLICK HERE TO GET THIS BOOKLow Abundance Proteome Discovery

Low-Abundance Proteome Discovery

Low-Abundance Proteome Discovery
  • Author : Egisto Boschetti,Pier Giorgio Righetti
  • Publisher : Newnes
  • Release : 26 March 2013
GET THIS BOOKLow-Abundance Proteome Discovery

Low-Abundance Proteome Discovery addresses the most critical challenge in biomarker discovery and progress: the identification of low-abundance proteins. The book describes an original strategy developed by the authors that permits the detection of protein species typically found in very low abundance and that may yield valuable clues to future discoveries. Known as combinatorial peptide ligand libraries, these new methodologies are one of the hottest topics related to the study of proteomics and have applications in medical diagnostics, food quality, and

Proteomic and Metabolomic Approaches to Biomarker Discovery

Proteomic and Metabolomic Approaches to Biomarker Discovery
  • Author : Haleem J. Issaq,Timothy D. Veenstra
  • Publisher : Academic Press
  • Release : 24 October 2019
GET THIS BOOKProteomic and Metabolomic Approaches to Biomarker Discovery

Proteomic and Metabolomic Approaches to Biomarker Discovery, Second Edition covers techniques from both proteomics and metabolomics and includes all steps involved in biomarker discovery, from study design to study execution. The book describes methods and presents a standard operating procedure for sample selection, preparation and storage, as well as data analysis and modeling. This new standard effectively eliminates the differing methodologies used in studies and creates a unified approach. Readers will learn the advantages and disadvantages of the various techniques

Neuroscience Biomarkers and Biosignatures

Neuroscience Biomarkers and Biosignatures
  • Author : Institute of Medicine,Board on Health Sciences Policy,Forum on Neuroscience and Nervous System Disorders
  • Publisher : National Academies Press
  • Release : 08 January 2008
GET THIS BOOKNeuroscience Biomarkers and Biosignatures

Biomarkers, or biological markers, are quantitative measurements that offer researchers and clinicians valuable insight into diagnosis, treatment and prognosis for many disorders and diseases. A major goal in neuroscience medical research is establishing biomarkers for disorders of the nervous system. Given the promising potential and necessity for neuroscience biomarkers, the Institute of Medicine Forum on Neuroscience and Nervous System Disorders convened a public workshop and released the workshop summary entitled Neuroscience Biomarkers and Biosignatures: Converging Technologies, Emerging Partnerships. The workshop

Agricultural Proteomics Volume 1

Agricultural Proteomics Volume 1
  • Author : Ghasem Hosseini Salekdeh
  • Publisher : Springer
  • Release : 20 August 2016
GET THIS BOOKAgricultural Proteomics Volume 1

This book will cover several topics to elaborate how proteomics may enhance agricultural productivity. These include crop and food proteomics, farm animal proteomics, aquaculture, microorganisms and insect proteomics. It will also cover several technical advances, which may address the current need for comprehensive proteome analysis.An emerging field of the proteomics aim is to integrate knowledge from basic sciences and to translate it into agricultural applications to solve issues related to economic values of farm animals, crops, food security, health,

Genomics and Proteomics for Clinical Discovery and Development

Genomics and Proteomics for Clinical Discovery and Development
  • Author : György Marko-Varga
  • Publisher : Springer
  • Release : 26 August 2014
GET THIS BOOKGenomics and Proteomics for Clinical Discovery and Development

The book is intended to be a resource for students as well as scientists in education and for the general public to learn about proteomics and genomics. Chromosomes form the basis for our genetic heritage and are the code for protein synthesis. The Human Genome Map came out in 2002, and the Proteome Sequence Map is under currently being created by a global consortia initiative. Proteome and genome building blocks already form the basis of scientific research areas as well as

Biological Mass Spectrometry

Biological Mass Spectrometry
  • Author : A.L. Burlingame
  • Publisher : Gulf Professional Publishing
  • Release : 12 December 2005
GET THIS BOOKBiological Mass Spectrometry

This volume describes and integrates the techniques and fundamentals of more than a decade of revolutionary advances in both chromatographic and mass spectrometric technologies that have enabled the direct investigation of biomacromolecules per se and have provided the analytical power base to usher in the new fields of proteomics and systems biology. It also covers new biophysical applications such as H/D exchange for study of conformations, protein-protein and protein-metal and ligand interactions. Finally it describes atto-to-zepto-mole quantitation of 14C

Proteomic and Metabolomic Approaches to Biomarker Discovery

Proteomic and Metabolomic Approaches to Biomarker Discovery
  • Author : Haleem J Issaq,Timothy D. Veenstra
  • Publisher : Academic Press
  • Release : 20 May 2013
GET THIS BOOKProteomic and Metabolomic Approaches to Biomarker Discovery

Proteomic and Metabolomic Approaches to Biomarker Discovery demonstrates how to leverage biomarkers to improve accuracy and reduce errors in research. Disease biomarker discovery is one of the most vibrant and important areas of research today, as the identification of reliable biomarkers has an enormous impact on disease diagnosis, selection of treatment regimens, and therapeutic monitoring. Various techniques are used in the biomarker discovery process, including techniques used in proteomics, the study of the proteins that make up an organism, and

Protein Purification

Protein Purification
  • Author : Jan-Christer Janson,Lars Rydén,Lars Ryden
  • Publisher : John Wiley & Sons
  • Release : 20 May 1998
GET THIS BOOKProtein Purification

This is a state-of-the-art sourcebook on modern high-resolution biochemical separation techniques for proteins. It contains all the basic theory and principles used in protein chromatography and electrophoresis.

Quantitative Proteomics

Quantitative Proteomics
  • Author : Claire E Eyers,Simon J Gaskell
  • Publisher : Royal Society of Chemistry
  • Release : 11 February 2014
GET THIS BOOKQuantitative Proteomics

As a component of post-genome science, the field of proteomics has assumed great prominence in recent years. Whereas quantitative analyses focussed initially on relative quantification, a greater emphasis is now placed on absolute quantification and consideration of proteome dynamics. Coverage of the topic of quantitative proteomics requires consideration both of the analytical fundamentals of quantitative mass spectrometry and the specific demands of the problem being addressed. Quantitative Proteomics aims to outline the state of the art in mass spectrometry-based quantitative

Serum/Plasma Proteomics

Serum/Plasma Proteomics
  • Author : Richard J Simpson,David W Greening
  • Publisher : Humana Press
  • Release : 01 May 2016
GET THIS BOOKSerum/Plasma Proteomics

Blood science has become a cornerstone of multiple disciplines. This book, contributed to by leading experts in the field, provides a comprehensive resource of protocols for areas, pre-analytical through to analytical, of plasma and serum proteomics.

Foodomics

Foodomics
  • Author : Alejandro Cifuentes
  • Publisher : John Wiley & Sons
  • Release : 05 February 2013
GET THIS BOOKFoodomics

Provides the latest "-omics" tools to advance the study of food and nutrition The rapidly emerging field of foodomics examines food and nutrition by applying advanced "-omics" technologies in order to improve people's health, well-being, and knowledge. Using tools from genomics, transcriptomics, epigenomics, proteomics, and metabolomics, foodomics offers researchers new analytical approaches to solve a myriad of current challenges in food and nutrition science. This book presents the fundamentals of foodomics, exploring the use of advanced mass spectrometry techniques in

Proteomic Applications in Cancer Detection and Discovery

Proteomic Applications in Cancer Detection and Discovery
  • Author : Timothy D. Veenstra
  • Publisher : John Wiley & Sons
  • Release : 30 May 2013
GET THIS BOOKProteomic Applications in Cancer Detection and Discovery

Helps researchers in proteomics and oncology work together tounderstand, prevent, and cure cancer Proteomic data is increasingly important to understanding theorigin and progression of cancer; however, most oncologicresearchers who depend on proteomics for their studies do notcollect the data themselves. As a result, there is a knowledge gapbetween scientists, who devise proteomic techniques and collect thedata, and the oncologic researchers, who are expected to interpretand apply proteomic data. Bridging the gap between proteomics andoncology research, this book explains how proteomic

Rapid Test

Rapid Test
  • Author : Laura Anfossi
  • Publisher : BoD – Books on Demand
  • Release : 26 September 2018
GET THIS BOOKRapid Test

Rapid tests, also known as point-of-care tests, have been in use for decades in the clinical and medical area and have become increasingly popular as an efficient screening method for conducting on-site analysis thanks to their simplicity, speed, specificity and sensitivity. Nowadays, rapid tests are widely applied for clinical, drug, food, forensic and environmental analysis and fields of application are rapidly increasing together with advances in the technology. The growing interest in rapid tests and their expanding application in diverse